--- Day changed Sun Oct 18 2009 02:06 -!- zancas [n=zancas@c-98-226-200-82.hsd1.il.comcast.net] has quit [Client Quit] 03:46 -!- genehacker [n=thisisno@pool-173-57-48-104.dllstx.fios.verizon.net] has quit [Read error: 113 (No route to host)] 04:42 -!- Trooem [i=Trooem@121.172.10.138] has quit [] 05:41 -!- ve [n=a@94-193-95-252.zone7.bethere.co.uk] has quit [Read error: 110 (Connection timed out)] 06:07 -!- Trooem [i=Trooem@121.172.10.138] has joined #HPLUSROADMAP 07:04 -!- Trooem [i=Trooem@121.172.10.138] has quit [] 07:27 -!- ve [n=a@94-193-95-252.zone7.bethere.co.uk] has joined #hplusroadmap 09:19 -!- Trooem [i=Trooem@121.172.10.138] has joined #hplusroadmap 09:31 < Utopiah> !seen fenn 09:32 < Utopiah> do you guys want a Supybot instance? for this and publishing daily logs? 09:48 -!- Trooem [i=Trooem@121.172.10.138] has quit [Read error: 110 (Connection timed out)] 11:15 < ybit> Utopiah: i suppose it couldn't hurt 11:59 -!- Noahj [n=noah@ip98-182-59-157.ri.ri.cox.net] has joined #hplusroadmap 12:27 < kanzure> ybit: fenn and i were thinking of not sleeping. $50/night looks ok but honestly i think we could do better if we find some transhumans to sleep with. 12:28 < kanzure> ybit: togetic seems to be down? 71.228.183.181 12:28 < kanzure> it doesn't seem to be located at ybit.ath.cx either 12:28 < Utopiah> kanzure: do you have a link to fenn sleeping/activity patterns? iirc he even made colorful visuals 12:29 < kanzure> QuantumG is still around and posts frequently to slashdot. percent thinks i'm the devil and will kill all humans indirectly (and "perhaps directly") 12:29 < kanzure> i'll have to go look at the mailbox in a bit. i'm at the wrong location. 12:30 < kanzure> ybit: kottke is going to have to find some other friends, 6hr is too long 12:30 < kanzure> Utopiah: http://fennetic.net/sleep/ 12:30 < Utopiah> thanks kanzure 12:31 < kanzure> ybit: i was trying to log in to fix your # 12:31 < kanzure> skdb.core.units.UnitError: pi/2 radians: Unknown unit 'pi' 12:32 < kanzure> ybit: you should send paper requests also to getarticles@googlegroups.com, and when you get responses, forward the papers to papers@postbiota.org 12:39 < drazak> kanzure: do people not read the most recent posts before the post to diybio? 12:39 < drazak> I repeated 4 times that GFP was a bad idea 12:43 < kanzure> in general they do not read 12:43 < kanzure> (anything) 12:43 < kanzure> eric hunting just repeated pepakura information from over a year ago from open manufacturing, for instance 12:43 < kanzure> that's something he should have known about back then 12:48 < drazak> that Cathal guy seems to be pretty on top of everything 12:48 < drazak> it's just some of the other moron on the list that have no fucking clue 12:48 < drazak> about anything, really 12:49 < kanzure> i can't seem to find any cheap automatic book scanners that either flip pages or take in a stack of pages. kirtas-tech.com sells one used for $100k USD (wtf) 12:49 < kanzure> my mom made a deal with me- if, in the move, i give up 4 boxes of books, she would buy me a book scanner 12:49 < drazak> get her to spring for the 100k$ one then 12:49 < drazak> :P 12:50 < kanzure> no way, how is it that there's nothing cheaper on ebay? 12:50 < kanzure> i mean, even a $10k used one? really, nothing? 12:51 < kanzure> iirc, xerox machines have this feeder-paper-bay for bulk throughput scanning 12:53 < kanzure> http://www.davidco.com/forum/showthread.php?t=9328 suggests an industrial paper cutter (400 pg/cut) 12:54 < kanzure> lots of those on ebay: http://shop.ebay.com/?_from=R40&_trksid=p3907.m38.l1313&_nkw=industrial+paper+cutter&_sacat=See-All-Categories 12:56 < kanzure> and then a pass-through scanner. how do you tell how big the input bay is? (how many pages it can hold without snapping in half or not accepting more paper)? 13:07 < ybit> oh yeah, i forgot percent became a defender of dumbland 13:08 < ybit> 12:32 < kanzure> ybit: you should send paper requests also to getarticles@googlegroups.com 13:08 < ybit> ah forgot i was on that group 13:08 < ybit> why not the lego book scanner? 13:10 < ybit> s/dumbland/non-free&open land? 13:10 < ybit> something like that 13:25 -!- ybit_ [i=ybit@dhcp-84-36.me.utexas.edu] has joined #hplusroadmap 13:25 -!- ybit_ [i=ybit@dhcp-84-36.me.utexas.edu] has quit [Client Quit] 13:47 < ybit> kanzure: so what's this sabbatical you and fenn have been on? :-) 13:47 < kanzure> moved down the street 13:58 * kanzure suspects ybit isn't metric 14:19 -!- genehacker [n=thisisno@pool-173-57-48-104.dllstx.fios.verizon.net] has joined #hplusroadmap 14:44 -!- genehacker [n=thisisno@pool-173-57-48-104.dllstx.fios.verizon.net] has quit [] 14:51 -!- genehacker [n=thisisno@pool-173-57-48-104.dllstx.fios.verizon.net] has joined #hplusroadmap 14:53 -!- ve_ [n=a@94-193-95-252.zone7.bethere.co.uk] has joined #hplusroadmap 15:05 < drazak> kanzure: what time is it in texas? 15:06 < ybit> 3:02 drazak 15:06 < ybit> cst like mine 15:07 < ybit> er, 3:09 my clocked isn't synced :\ 15:08 < genehacker> it is 3:11 pm 15:08 < ybit> drazak: why do you ask? :-) 15:08 < drazak> because I wasn't sure if it was CST or the next one west 15:08 < ybit> genehacker: what classes are you taking this semester, just curious after you mentioned them last night. 15:09 < genehacker> are you in texas drazak? 15:09 < drazak> no 15:09 < drazak> I'm in ny 15:09 -!- ve [n=a@94-193-95-252.zone7.bethere.co.uk] has quit [Read error: 110 (Connection timed out)] 15:09 -!- ve_ is now known as ve 15:10 < drazak> but I might go to rice or that school you guys are at 15:10 -!- zancas [n=zancas@c-24-14-46-37.hsd1.il.comcast.net] has joined #hplusroadmap 15:10 < genehacker> ybit I'm taking hard ones 15:10 < genehacker> the lab for one is insane 15:15 < genehacker> as in it takes 48 hrs of work to complete a lab assigment 15:16 < ybit> genehacker: okay, so what courses are you taking? :P 15:16 < ybit> genehacker: drazak is in buffalo, ny 15:16 < genehacker> why do you ask? 15:16 < ybit> because i'm curious 15:16 < genehacker> ok 15:17 < genehacker> materials processing, statistics, fluids, materials processing lab, and the horror of the old ones 15:18 < ybit> hehe 15:18 < genehacker> I have omitted some though 15:19 < ybit> that's fine, probably just basics or something like that 15:19 < ybit> those are what i was interested in 15:20 < ybit> i've never been able to handle more than 16hrs 15:20 < genehacker> I don't think it's more than 16hrs 15:20 < genehacker> yet it's still insane 15:20 < ybit> i'm sure it is 15:21 * ybit is looking for multimachine parts list, about to head to the junkyard and round up most of them for my exercise today 15:22 < genehacker> a working multimachine? 15:22 < genehacker> impossible 15:22 < ybit> surely 15:22 < genehacker> doe the multimachine just bend stuff? 15:22 < ybit> http://d.yimg.com/kq/groups/13335163/homepage/name/homepage.jpg?type=sn makes me think it exists 15:23 < ybit> "The MultiMachine is an accurate all-purpose machine tool that can be used as a metal or wood lathe, end mill, horizontal mill, drill press, wood or metal saw or sander, surface grinder and sheet metal "spinner". It can be built by a mechanic using just common hand tools. For machine construction, electricity can be replaced with "elbow grease" and all the necessary material can come from discarded vehicle parts and steel bar."d 15:25 < genehacker> http://users.telenet.be/O-tiose/images/sasquatch01.jpg 15:26 < ybit> http://ybit.ath.cx/misc_docs/How%20to%20build%20a%20multimachine.pdf 15:35 < ybit> omfg, imagine that. http://opensourcemachine.org/the-multimachine/multimachine-video 15:36 < ybit> ..it works 15:41 -!- Trooem [i=Trooem@121.172.10.138] has joined #hplusroadmap 15:42 -!- Trooem [i=Trooem@121.172.10.138] has quit [Client Quit] 15:43 < genehacker> ok 15:43 < genehacker> then 15:43 < genehacker> good luck 15:46 < ybit> heh, thanks. i figure it's something to play around with afk 15:47 < genehacker> almost forgot 15:47 < genehacker> I learned of something amazing the other day 15:48 < genehacker> amazing software that does the impossible 15:48 < genehacker> software that does fatigue testing in software 15:54 < ybit> genehacker: link? 15:57 < ybit> or just a name of the program.. 15:57 < ybit> you can't leave me hanging with "oh i have this great life-changing secret, well ttyl" :-) 15:58 < drazak> i'm leaving to go to ac/dc in a few 16:02 < ybit> A study in humans published in 2006 hints at a link between 16:02 < ybit> Parkinson's and a prolonged exposure to amphetamine in any form (not just 16:02 < ybit> that prescribed for ADHD). 16:03 < ybit> ...Before Parkinson's symptoms such as tremors and 16:03 < ybit> muscle rigidity appear, however, dopamine's function in the brain must 16:03 < ybit> decline by 80 to 90 percent, or by about twice as much as what Ricaurte and 16:03 < ybit> his colleagues saw in baboons that were drinking a more moderate dose of the 16:03 < ybit> drug. And some studies have found no connection between stimulant use and 16:03 < ybit> Parkinson's. 16:06 < genehacker> they feed in electron microscope data and it tells where an engine block will fail 16:06 < genehacker> I have no link 16:06 < genehacker> that is the problem 16:06 < genehacker> I heard about it from a friend 16:07 < genehacker> but if we could apply it to skdb it would allow skdb to do pretty much everything 16:16 < ybit> if you could get that friend to recall the name of it, that would be appreciated 16:17 < drazak> mmmm ac/dc 16:32 -!- zancas [n=zancas@c-24-14-46-37.hsd1.il.comcast.net] has quit [Client Quit] 16:35 -!- genehacker [n=thisisno@pool-173-57-48-104.dllstx.fios.verizon.net] has quit [Read error: 113 (No route to host)] 16:39 < ybit> kanzure: i know you are aware of it, but maybe you have forgotten, if the $10k funding falls through, y-combinator might be an option later on, they will fund you ~$15k for a couple of months so that you can prepare to have a product ready to be presented to VCs. 16:39 < ybit> http://ycombinator.com/ 16:40 < Utopiah> iirc #startups has people with Y-Combinator funding 16:43 < ybit> thanks Utopiah 16:45 < ybit> "Heath, everything begins at 9 am both Saturday and Sunday. There will be a 16:45 < ybit> party Saturday night. Ticket prices are still $150, but go up for each 50 16:45 < ybit> that we sell. " 16:46 * ybit will have to double the dosage of stimulants to be the least bit attentive that early 16:46 < ybit> or at least 20mg 16:47 < ybit> drazak: enjoy that concert, represent the channel and do something nerdy 16:58 * ybit wonders who bct, boogles, branstrom, chizu, flamoot, kanzure, ve, and zvader are. 16:58 < ybit> -kanzure 16:59 < ybit> er, s/kanzure/ kardan_ 16:59 < branstrom> Fairly recently converted h+ wannabe from Sweden 17:00 < ybit> branstrom: we're all transhuman wannabes :) 17:00 < ybit> branstrom: what are your research interests and hobbies? 17:01 < branstrom> I've read a lot of Dennett... Then I read On Intelligence. Then I started reading Overcoming Bias & Less Wrong. 17:01 < ybit> who here do you know? how did you hear about the channel? do you like cream with your coffee? ;) 17:02 < branstrom> I'm working on my GED to get into college and study AGI/neuroscience 17:02 < branstrom> Don't know anybody here :) 17:02 < ybit> http://www.google.com/url?sa=t&source=web&ct=res&cd=2&ved=0CA4QFjAB&url=http%3A%2F%2Fwww.grossmont.edu%2Fbertdill%2Fdocs%2FCollegeWaste.pdf ;; "College is a Waste of Time and Money" 17:03 < branstrom> I think I found a link somewhere on a website to this channel. Coffee tastes like donkey poo. 17:03 < ybit> and yet i keep going back to it 17:04 < ybit> it, being college 17:04 < ybit> think this may be my third time to sit out for a semester 17:05 < branstrom> Interesting, I'll take a look at that article. 17:05 < ybit> let's see.. i've sat out more than that... wow, 3.5 years, total, i've sat out 17:06 < branstrom> I'm probably a good fit for college though... 17:07 -!- ve [n=a@94-193-95-252.zone7.bethere.co.uk] has quit [Read error: 110 (Connection timed out)] 17:07 < ybit> i fit in well, just get tired of it 17:10 < kardan_> hi ybit, just found your ping but didnt get the context 17:27 * katsmeow-afk swaps out all branstrom's coffee 17:28 < branstrom> Seems to be a lot of people into DIY biology here 17:28 < ybit> diy in general 17:29 < ybit> kardan_: was just wondering who you were, research interests, hobbies, etc 17:34 -!- kardan_ is now known as kardan 17:35 < kardan> ybit: my interest is open source hardware in general: https://we.riseup.net/opensourcehardware 17:36 < kardan> we develop web applications on rails. crabgrass is one of our projects: crabgrass.riseup.net 17:38 < ybit> kanzure: http://superjared.com/entry/quick-django-benching/ 17:39 < kardan> we still have an open ticket with db specifications by kanzure. unfortunately we could not implement them yet .. too many side projects 17:39 < ybit> interesting 18:10 -!- Phreedom [n=quassel@195.216.211.175] has quit ["No Ping reply in 180 seconds."] 18:10 -!- Phreedom [n=quassel@195.216.211.175] has joined #hplusroadmap 18:26 -!- Phreedom [n=quassel@195.216.211.175] has quit ["No Ping reply in 180 seconds."] 18:26 -!- Phreedom [n=quassel@195.216.211.175] has joined #hplusroadmap 19:25 < branstrom> Oh, I'm coding Rails as well 19:25 < branstrom> Been toying/working with it since 2005 19:56 -!- ve [n=a@94-193-95-252.zone7.bethere.co.uk] has joined #hplusroadmap 19:59 -!- genehacker [i=genehack@wireless-128-62-38-232.public.utexas.edu] has joined #hplusroadmap 20:13 -!- kardan [n=kardan@p54BE6A2F.dip.t-dialin.net] has quit [Read error: 110 (Connection timed out)] 20:14 -!- kardan| [n=kardan@p54BE4859.dip.t-dialin.net] has joined #hplusroadmap 21:39 < kanzure> ybit: i got your package 21:41 < ybit> o good 21:41 < ybit> you should get another one tomorrow 21:42 < ybit> they're gifts, ya know, for taking the time to do this. it's to be split with fenn even if he does give you ugly looks while backing up the stuff :P where is he btw? 21:45 < ybit> kanzure 21:49 < ybit> and uh, you might not care for one of them :P i tried to cancel the order but the warehouse had already shipped it within 2 hours of the order o.O so, um, just wing it, pretend like it was useful :P 21:50 * ybit is feeling emotiriffic 21:50 < ybit> ..ya know because of all the emoticons.. maybe i should stop making up words 21:50 < katsmeow-afk> porque why? 21:51 < ybit> ^ 21:51 < katsmeow-afk> i don't know 21:51 < katsmeow-afk> you are making emoticons? 21:52 < ybit> i typed 3 of them in one line 21:52 < ybit> 21:18 "mom i need photos for the site. buy a camera and get a tax-writeoff." "heath, i've got a better idea, i'm about to buy one of those flip cameras and upload videos to youtube _and_ you can take stills from the video." 21:52 < ybit> i laughed 21:54 * katsmeow-afk is gonna unload apache and other webservers for one she made : http://designerthinking.com/images/Euphoria/euv4webserver2.html 21:54 < katsmeow-afk> it's only for local use behind a firewall, etc etc etc, and all those caveats 21:56 < ybit> grr for having to create html and css bologna 21:57 < katsmeow-afk> i used as little as possible for the ftp views, i even used
 to avoid css formatting if i could
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22:18 < genehacker> node quake
22:28 < drazak> I'm a little deaf
22:32 < kanzure> todo: grab  Genome evolution and adaptation in a long-term experiment with Escherichia coli
22:33 < katsmeow-afk> it's in Nature mag, i think
22:34 < katsmeow-afk> yep
22:34 < katsmeow-afk> Nature advance online publication 18 October 2009
22:36 < kanzure> there was a paper from this group from a while back about this experiment
22:36 < kanzure> it was what caused the lenski bullshit
22:36 < kanzure> anyway, anna salamon and i once schemed up a way to do this with human stem cell lines
22:36 < kanzure> so that we could do maybe 40,000 generations of selection on stem cells and then boot up the rest of the human at some future date
22:37 < kanzure> so that you don't have to actually have 40,000 generations of offspring living for at least 12+ years each
22:37 < drazak> so you want say
22:37 < drazak> 10000 passage stem cells
22:37  * drazak laughs
22:37 < drazak> glwt
22:38 < kanzure> passage?
22:38 < drazak> all immortalized cells start to deform after 500 passages
22:38 < drazak> passage is when you move the cells from one container to another
22:38 < drazak> usually after 3-6 doublings
22:38 < katsmeow-afk> i don't see how you can serialise genetic pressure and atthe same time shorten the evolution time
22:38 < kanzure> no i don't want to move them
22:38 < drazak> yes.. you do...
22:38 < kanzure> bullshit
22:38 < drazak> they will die if you don't
22:38 < kanzure> you don't even know my environment
22:38 < kanzure> i think you should stop while you're "ahead"
22:39 < drazak> go ahead and tell me
22:39 < katsmeow-afk> yea, kanzure has a fenn inhis environment!
22:39 < kanzure> no i mean there's no reason that we have to grow stem cells in a situation where we have to transfer them from plates
22:39 < kanzure> that's kind of silly for high throughput projects anyway
22:39 < kanzure> and apparently it's also silly for biological reasons too
22:39 < drazak> high throughput use large roller bottles
22:39 < kanzure> not always
22:39 < drazak> also transfering isn't what kills them
22:40 < kanzure> good night
22:40 < drazak> you don't seem to understand
22:40 < genehacker> heiflick limit?
22:40 < genehacker> hayflick
22:40 < drazak> genehacker: kind of
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22:41 < drazak> genehacker: it's a little different with stem cells
22:41 < drazak> genehacker: their chromosomes become no longer diploid
22:41 < drazak> kanzure: so how much cell culture have you actually done?
22:42 < genehacker2> now what books do I read to learn these things would probably be a better question to ask
22:46 < genehacker2> so what do you recommend?
22:46 < drazak> genehacker: a couple good biochem books
22:46 < genehacker2> ok
22:46 < drazak> I've read like 3 or 4 of them
22:46 < drazak> and I can't pick
22:47 < drazak> if you like medical biochem read stryers
22:49 < drazak> kanzure has stryers
22:49 < genehacker2> ok
22:51 < genehacker2> and these biochemistry books have this sort of information? or is this information that can only be gleaned from laboratory experience?
22:52 < drazak> well
22:52 < drazak> some of it is in there
22:53 < drazak> I have yet to find a good book on cell culture
22:53 < genehacker2> go figure
22:53 < genehacker2> it's a developing field
22:54 < drazak> most cell culture techniques haven't changed in 15 years
22:54 < genehacker2> many deformation processing techniques weren't put into a good book that compiled them for about 30 years
22:55 < genehacker2> I'll see if I can't digest stryers before moving on
22:55 < drazak> yeah
22:55 < drazak> it's big
22:55 < drazak> like 1700 page
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