--- Log opened Wed Jul 13 00:00:39 2011 00:19 -!- alystair [alystair@24-246-14-18.cable.teksavvy.com] has quit [Quit: ┌(・_・)┘OUTTA HERE└(・o・)┐] 00:43 -!- marainein [~marainein@124-168-86-98.dyn.iinet.net.au] has joined ##hplusroadmap 00:43 < kanzure> boop 00:43 < marainein> ? 00:43 < kanzure> never disturb me when i am booping 00:44 < marainein> my apologies 00:45 < fenn> beep 00:50 < kanzure> hi fenn 00:50 < kanzure> i couldn't sleep so i figured i'd work on my presentation 00:50 < kanzure> what am i presenting? 00:52 < fenn> "directed evolution of pathogens in human sweat bead bioreactors", and "scientific workshops as disease delivery mechanism" 00:52 < kanzure> nah they wanted me to babble about transhumanism 00:52 < fenn> oh. what's that? 00:52 < kanzure> for 10min.. so i figure motivations/goals/trends/projects should be enough 00:53 -!- klafka [~textual@cpe-69-205-70-55.rochester.res.rr.com] has quit [Quit: Computer has gone to sleep.] 00:53 < kanzure> "Your average transhumanist is a balding, middle-aged wanker who had the prime of his life in the 80s or early 90s after experimenting with LSD and acids." 00:54 < fenn> "i only take organic free range herbal acid 00:56 < kanzure> i am going to tell them that the lack of competency in "the upper ranks of the so-called transhumanist communities" is "a biosecurity concern because of the lack of communication, understanding and awareness of practical transhumanism" 00:59 < fenn> um. except it's not, because their incompetence simply ensures that nothing will happen 00:59 < kanzure> their incompetence ensures that they are not aware of what's going on 01:00 < kanzure> and having awareness (in their case) is insufficient 01:02 < kanzure> this isn't too important 01:07 < kanzure> ok i'll just call that "crippled by futorology" 01:39 < Utopiah> http://xkcd.com/924/ on 3D printer 01:41 < kanzure> yeah i don't really understand why people think that 3D printers have to be ubiquitous 02:09 < kanzure> http://diyhpl.us/~bryan/irc/diybiofbi2011.pdf 02:09 < kanzure> not bad for 4am 02:09 < fenn> speaking of 3d printers, the production quality of this video (solar sinter) is amazingly good for a student project vimeo.com/25401444 02:10 < kanzure> fenn: you should look at it and tell me why i suck 02:10 * fenn looks 02:10 < fenn> are you still affiliated with h+? 02:10 < kanzure> nope 02:10 < fenn> humanity+ i mean 02:10 < fenn> so their logo maybe isnt the best thing to put on the first slide 02:10 < kanzure> i realize this is confusing since i have the logo there 02:12 < fenn> so it may be best to frame things as "people will do these illegal things anyway, get used to it" rather than "i'm doing this and i'm here to poison the minds of your children" 02:12 < kanzure> right 02:12 < kanzure> that's prolly not evident by the slides but i do intend that 02:12 < fenn> i have difficulty thinking like an FBI agent so i don't really know what they want to hear 02:13 < kanzure> they want to hear about motivations and what sort of skills you probably have 02:13 < fenn> maybe you should have a slide about yourself then 02:13 < kanzure> ha ha no 02:14 * fenn shrugs 02:14 < kanzure> "Here we have a typical biohacker:" 02:14 < fenn> also may wish to cover patient advocacy 02:14 < kanzure> 'field guide to spotting molecular biologists' 02:14 < kanzure> hrmm okay 02:14 < fenn> orphan diseases etc 02:15 < kanzure> ah right. i forgot these things are called 'orphan' diseases 02:15 < fenn> FDA clinical trials process lets a lot of people die for lack of approval 02:15 < fenn> or decades long approval process 02:15 < kanzure> 1. read about some amazing cure from 15 years ago 02:15 < kanzure> 2. look up the patent 02:15 < kanzure> 3. cry because the VC money hasn't produced a drug yet 02:15 < fenn> the fallout from these diy medical researchers might lead to some epic transhuman technology 02:15 < kanzure> 4. do what the patent says anyway 02:17 < fenn> did you read that book with the mind-erasing fractal basilisk, uh... 02:17 < kanzure> basiwhat 02:18 < fenn> main character falls into a pond in winter and half of his brain cells die. they use some sort of stem cell therapy to rejuvenate the dead parts of his brain, but he comes out of it smarterthan he was before 02:18 < fenn> intrigued by the possibilities of this, he starts researching the mechanisms of the drug or therapy or whatever, and bootstraps his own intelligence 02:18 < kanzure> zindell probably stole that and put it into neverness 'cept it was bio-nano-something fixing the brain 02:18 < fenn> no this was pretty straightforward, you kill the existing brain and re-grow it better 02:19 < kanzure> short story? 02:19 < fenn> yeah 02:19 < fenn> one moment 02:19 < kanzure> "undrstand" by te chiang-something-or-other? 02:19 < kanzure> *understand 02:20 < kanzure> i'm gonna try me some more of that sleeps 02:20 < fenn> hm. it's not "none so blind" but that's a good one too 02:21 < fenn> can't find it. nevermind. 02:21 < fenn> oh, yes, "understand" by ted chiang 02:22 < fenn> why isnt that in my book list 02:24 < fenn> i love how the doctors are all, "we've never one this before, but don't worry, you'll be fine." 02:36 < fenn> this is sort of how i felt last week 02:37 < fenn> last weekend. time seems to be going faster 02:42 < kanzure> i wonder which part of the brain i need to melt to stop the time thingy 02:43 < kanzure> also why is sunrise at 5am in nyc 02:43 < fenn> hm? why would you want to do that 02:43 < kanzure> what sort of black magic is this 02:43 < kanzure> i want time to be slower, not faster 02:43 -!- ybit2 [~yottabit@c-69-137-22-58.hsd1.al.comcast.net] has joined ##hplusroadmap 02:43 < fenn> eh, well its sort of hard to explain 02:43 < fenn> on the one hand i seem to do a lot of stuff in any given hour 02:43 < fenn> on the other hand i look up and the day's halfway over already and i havent had breakfast 02:44 < kanzure> i thought that's normal? 02:44 < fenn> no 02:44 < kanzure> oorly 02:44 < kanzure> steve hasn't had breakfast in like five years! 02:44 < fenn> good for him 02:44 < kanzure> :p but really, it happens to me all the time 02:44 < fenn> i usually make a point to have breakfast within an hour of waking up 02:44 < kanzure> speaking of which.. 02:45 < fenn> today (yesterday actually) i had: half an apple, half a glass of apple juice, 02:45 < fenn> yogurt and pine nuts 02:46 < fenn> and two slices of pizza an hour ago 02:47 -!- ybit [~yottabit@c-69-137-22-58.hsd1.al.comcast.net] has quit [Ping timeout: 255 seconds] 02:52 < kanzure> i wonder if this hotel serves cold pizza for breakfast 02:57 < fenn> try the dumpster behind the pizza place :) 03:03 < foucist> genius 03:03 < foucist> fenn: you are a master dumpster diver! 03:03 < foucist> lets build a rocket ship with your skills and my know how! 03:04 < foucist> we'll colonize a NEA as the first step 03:04 < foucist> then spin it for centripetal gravity 03:27 < fenn> gravity is for landlubbers 03:27 < fenn> but i agree 03:34 < foucist> fenn: at least i'm avoiding the pure silliness of colonizing planets (gravity holes are lame!) 03:35 < foucist> fenn: but we do need some gravity or some way of keeping our bodies from falling apart 03:35 < foucist> unless we develop genetic engineering or other tech to deal with that 03:48 < fenn> electric bone tissue stimulation should help with calcium loss/porosity 03:48 < fenn> of course exercise is necessary but i'm not sure we need gravity for that 03:48 < fenn> anyway you dont have to spin the whole damn asteroid 03:49 < fenn> bernal had the right idea 03:49 < fenn> 1929 holy fuck 04:47 -!- uniqanomaly [~ua@dynamic-78-8-82-200.ssp.dialog.net.pl] has joined ##hplusroadmap 05:35 -!- Juul [~Juul@2001:470:dc98:2:218:deff:fe2a:4335] has joined ##hplusroadmap 05:44 -!- lumos [~lumos@afae237.neoplus.adsl.tpnet.pl] has joined ##hplusroadmap 06:02 -!- el_kevino [~el_kevino@tor.office.avidlifemedia.com] has joined ##hplusroadmap 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[~neuralnet@unaffiliated/archels] has joined ##hplusroadmap 09:32 -!- eridu [~eridu@gateway/tor-sasl/eridu] has quit [Ping timeout: 250 seconds] 09:33 < foucist> fenn: i was thinking train tracks around the asteroid could work 09:57 -!- eridu [~eridu@gateway/tor-sasl/eridu] has joined ##hplusroadmap 10:16 -!- uniqanomaly [~ua@dynamic-78-8-82-200.ssp.dialog.net.pl] has quit [Quit: uniqanomaly] 10:38 -!- Juul [~Juul@2001:470:dc98:2:218:deff:fe2a:4335] has quit [Quit: Leaving] 10:53 -!- eridu [~eridu@gateway/tor-sasl/eridu] has quit [Ping timeout: 250 seconds] 11:35 -!- eridu [~eridu@gateway/tor-sasl/eridu] has joined ##hplusroadmap 11:40 -!- He||eshin is now known as Helleshin 12:01 -!- eridu [~eridu@gateway/tor-sasl/eridu] has quit [Quit: Leaving] 12:22 -!- AlonzoTG [~atg@dsl092-168-049.wdc2.dsl.speakeasy.net] has quit [Ping timeout: 260 seconds] 12:22 -!- ybit2 [~yottabit@c-69-137-22-58.hsd1.al.comcast.net] has quit [Ping timeout: 240 seconds] 13:07 -!- outer_space 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15:17 -!- AlonzoTG [~atg@dsl092-168-049.wdc2.dsl.speakeasy.net] has joined ##hplusroadmap 15:28 -!- ybit [~yottabit@c-69-137-22-58.hsd1.al.comcast.net] has quit [Ping timeout: 255 seconds] 15:52 -!- ybit [~yottabit@108-199-8-125.lightspeed.brhmal.sbcglobal.net] has joined ##hplusroadmap 15:55 -!- eudoxia [~eudoxia@r190-135-27-90.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 16:21 -!- marainein [~marainein@124-149-84-47.dyn.iinet.net.au] has joined ##hplusroadmap 16:25 -!- elmom [~elmom@hoasnet-fe2add00-191.dhcp.inet.fi] has quit [Ping timeout: 240 seconds] 16:39 -!- elmom [~elmom@hoasnet-fe2add00-191.dhcp.inet.fi] has joined ##hplusroadmap 16:55 -!- lumos [~lumos@afaa199.neoplus.adsl.tpnet.pl] has joined ##hplusroadmap 17:03 -!- outer_space [~josh@12.117.161.34] has quit [Read error: Operation timed out] 17:16 -!- thesnark [~michael@cblmdm24-53-167-49.buckeyecom.net] has joined ##hplusroadmap 17:37 < fenn> foucist: you read that in red mars didnt you 17:37 < fenn> kanzure: can you recommend a php crash course? (don't ask) 17:37 < fenn> something along the lines of "dive into python" 17:45 -!- PixelScum [~PixelScum@ip98-177-175-88.ph.ph.cox.net] has quit [Read error: Connection reset by peer] 17:46 -!- Drakkar [~PixelScum@ip98-177-175-88.ph.ph.cox.net] has joined ##hplusroadmap 17:47 -!- thesnark [~michael@cblmdm24-53-167-49.buckeyecom.net] has quit [Remote host closed the connection] 17:54 -!- eudoxia [~eudoxia@r190-135-27-90.dialup.adsl.anteldata.net.uy] has quit [Ping timeout: 246 seconds] 18:01 -!- ybit [~yottabit@108-199-8-125.lightspeed.brhmal.sbcglobal.net] has quit [Changing host] 18:01 -!- ybit [~yottabit@unaffiliated/ybit] has joined ##hplusroadmap 18:29 -!- ybit [~yottabit@unaffiliated/ybit] has quit [Ping timeout: 260 seconds] 18:30 -!- ybit [~yottabit@c-69-137-22-58.hsd1.al.comcast.net] has joined ##hplusroadmap 18:42 -!- outer_space [~josh@12.117.161.34] has joined ##hplusroadmap 18:44 < kanzure> fenn: surprisingly no 18:44 < kanzure> php doesn't work like that 18:46 < kanzure> so that was an interesting day 18:46 < kanzure> nathan mccorkle is like charlie manion in person 18:46 < kanzure> (genehacker) 18:46 < kanzure> outer_space: are you perfetto 18:47 < outer_space> is that 'perfect' in a romance language? 18:47 < kanzure> no it's someone's name (josh perfetto) 18:47 < outer_space> I wouldn't disagree 18:47 < outer_space> no, josh jordan 18:47 < kanzure> did i do something with your daughter 18:47 < outer_space> did i do something to make a daughter? 18:47 < outer_space> maybe.... 18:49 < kanzure> hm then i probably don't know you 18:49 < kanzure> what's up 18:49 < outer_space> lol you got people hunting you or something? 18:50 < outer_space> im in san antonio, i need some cnc work 18:51 < kanzure> neat looking for anything in particular 18:51 < outer_space> is your austin machine shop there yet? 18:51 < kanzure> there's a few shops available 18:51 < outer_space> yes, robot arms from the thingiverse design 18:51 < kanzure> the omegle thing? 18:52 < kanzure> er, omioron 18:52 < outer_space> not for sale thru thingiverse for some reason 18:52 < kanzure> er.. i forget the spelling 18:52 < outer_space> but the design is for download 18:52 < kanzure> is it the laser cut acrylic arm thing from a group starting with 'o'? 18:52 < outer_space> by oomlout 18:52 < kanzure> ah yes 18:53 < kanzure> btw have you tried the san antonio hackerspace 18:53 < outer_space> never heard of it 18:54 < kanzure> oomlaut makes money selling those btw so you can probably look them up 18:54 < outer_space> i didnt think a hackerspace could happen in san antonio 18:56 < outer_space> i would buy from oomlaut but i cant find a link or a price 18:58 < outer_space> plus I want a bigger one that uses cordless drill dc server-motors 19:06 < kanzure> oh geeze i'm looking through the results of the iftf open fabrication workshop i attended 19:06 < kanzure> they spend a lot of time talking about "DNCA" and thingiverse 19:06 < kanzure> the Digital Necrophilia Copyright Act? 19:07 < QuantumG> heh 19:08 < kanzure> i'm "not supposed to distribute this" 19:08 < kanzure> so get in line.. you know the drill 19:09 -!- ybit [~yottabit@c-69-137-22-58.hsd1.al.comcast.net] has quit [Ping timeout: 258 seconds] 19:10 < outer_space> sa hackerspace has a few cordless drills and a drill press 19:10 < outer_space> i need a CNC do we have computers in san antonio or what 19:11 -!- ybit [~yottabit@108-199-8-125.lightspeed.brhmal.sbcglobal.net] has joined ##hplusroadmap 19:11 -!- archels [~neuralnet@541ED8B0.cm-5-7d.dynamic.ziggo.nl] has quit [Ping timeout: 260 seconds] 19:11 < outer_space> they dont even have a cnc on their wishlist 19:11 -!- archels [~neuralnet@541ED8B0.cm-5-7d.dynamic.ziggo.nl] has joined ##hplusroadmap 19:12 < outer_space> my dad's garage is a better hackerspace than this 19:25 < kanzure> yes some of these hackerspaces are pretty sad 19:25 < kanzure> fenn: there's a group of people at noisebridge doing biology stuff now.. you should go say hi 19:25 < kanzure> (the bioboard stuff that i ignored) 19:39 < outer_space> so is there a cnc somewhere in austin that i could pay to use or pay someone to use? 19:43 < QuantumG> try http://hackerspaces.org/wiki/Austin 19:44 -!- lumos [~lumos@afaa199.neoplus.adsl.tpnet.pl] has quit [Quit: Leaving] 19:50 < kanzure> this was exactly what it was like at the fbi today 19:50 < kanzure> including the black agent 19:50 < kanzure> http://www.youtube.com/watch?v=zMk1W9jE4xs#t=30 19:52 < outer_space> so there only 1 hackerspace in austin that has a cnc and its "<100% working" ? 19:52 < kanzure> uh well i have a bridgeport available 19:53 < kanzure> but i'm sort of on the wrong side of the continent 19:53 < kanzure> at the moment 19:59 -!- klafka [~textual@cpe-69-205-70-55.rochester.res.rr.com] has joined ##hplusroadmap 20:00 -!- eridu [~eridu@gateway/tor-sasl/eridu] has joined ##hplusroadmap 20:20 < QuantumG> why is that even up? 20:20 < QuantumG> like, was there a point to uploading that? 20:20 < QuantumG> it just seems like the most mundane bit of sci-fi ever 20:21 < QuantumG> roll intro credits 20:25 < outer_space> is there a cnc anywhere in texas? 20:29 < QuantumG> you know there's hundreds of them right? It's just that people use them for *manufacturing business* and don't generally allow random people access to them. 20:29 < QuantumG> try a tech college or something 20:45 -!- outer_space [~josh@12.117.161.34] has quit [Ping timeout: 246 seconds] 21:02 -!- eridu [~eridu@gateway/tor-sasl/eridu] has quit [Quit: Leaving] 21:10 < kanzure> rob pointed me to basically 21:10 < kanzure> http://nextbigfuture.com/2011/04/gene-synthesis-costs-have-been-slower.html 21:10 < kanzure> "135 pages of supplemental material - High-fidelity gene synthesis by retrieval of sequence-verified DNA identified using high-throughput pyrosequencing" 21:13 < kanzure> those numbers seem to be all over the place 21:14 < kanzure> http://omicsomics.blogspot.com/2011/02/will-cheap-gene-synthesis-squelch.html 21:16 < kanzure> apparently one of the 20under20 kids is working on this, but i forget which 21:17 < kanzure> http://nar.oxfordjournals.org/content/38/8/2514.long 21:18 < kanzure> "In this work, we describe a microfluidic platform for parallel solid phase synthesis of oligonucleotides that can greatly reduce the cost of gene synthesis by reducing reagent consumption (by 100-fold) while maintaining a ~100 pmol synthesis scale." 21:28 < kanzure> http://www.reddit.com/r/nootropics looks less active than imminst.org 21:30 < kanzure> someone should make a nootstack.org site to rate nootropic stacks. everyone posts the same questions everywhere except it's not organized. and it should be. 21:36 < foucist> kanzure: a stack overflow type site for noots? 21:37 < foucist> i like that idea! 21:38 < kanzure> apparently they raided this guy's place a while back 21:38 < kanzure> found lentiviral engineering going on 21:39 < kanzure> district attorney decided not to press any charges.. nothing they could do after that 21:45 < kanzure> okay here are my notes from today 21:45 < kanzure> http://diyhpl.us/~bryan/irc/2011-07-13-diybio-fbi-notes.txt 21:46 < kanzure> i'll push my commits later.. but for now there's that 22:20 < kanzure> wonder where this came from http://mass-customization.blogs.com/files/tseng-2010-open-manufacturing.pdf 23:05 -!- superkuh [~superkuh@unaffiliated/superkuh] has quit [Ping timeout: 250 seconds] 23:07 -!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap 23:11 < kanzure> welcome back superkuh 23:35 -!- PixelScum [~PixelScum@ip98-177-175-88.ph.ph.cox.net] has joined ##hplusroadmap 23:39 -!- Drakkar [~PixelScum@ip98-177-175-88.ph.ph.cox.net] has quit [Ping timeout: 276 seconds] --- Log closed Thu Jul 14 00:00:41 2011