--- Log opened Wed May 30 00:00:25 2012 00:07 -!- sylph_mako [~mako@118-93-5-109.dsl.dyn.ihug.co.nz] has joined ##hplusroadmap 00:45 -!- yashgaroth [~f@cpe-66-27-117-179.san.res.rr.com] has quit [Quit: Leaving] 01:07 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has quit [Quit: Leaving.] 01:36 -!- ThomasEgi [~thomas@pppdyn-0f.stud-ko.rz-online.net] has joined ##hplusroadmap 01:36 -!- ThomasEgi [~thomas@pppdyn-0f.stud-ko.rz-online.net] has quit [Changing host] 01:36 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap 01:40 -!- thyla [~userid@c-24-61-126-211.hsd1.nh.comcast.net] has left ##hplusroadmap [] 02:13 < Utopiah> starting tomorrow http://www.seasteading.org/community/events/conference2012/ 02:19 < ThomasEgi> nice, except that "save" and "economical" won't mix. because building a seastead that survives freakwaves just aint too cheap^ 02:20 < ThomasEgi> are you going to attend? 02:21 < Utopiah> nop, I think it's cool as an ideal but in practice, I dont believe one of the spectrum (Sealand, Amsterdam, Switzerland, Jersey) vs. Singapour make such a huge difference in term of lifestyle and creative "output" 02:24 < ThomasEgi> hm. well it can make some sense when you are more interested in political and juristical points 02:25 < ThomasEgi> i still prefer the idea of just digging a hole into the ground and live there. saves you tons of issues from offshore. 02:26 < Utopiah> I still think it's interesting, that's why I keep an eye on it, but again, we all complain about how restrictive our institutions are but usually we find simple loopholes that doesn't make it worth moving all the stuff far away in hard to live places 02:30 < ThomasEgi> basically. all you need to do is to find a place where noone cares what you are doing 02:30 < Utopiah> which IMHO is nowhere as long as it becomes intersting enough 02:30 < Utopiah> if this really takes off and "crazy" stuff happens, Im sure governments will react 02:31 < ThomasEgi> of course they will. 02:31 < ThomasEgi> that is why i prefer to have 2000m of granite between me, and the government :D 02:31 < ThomasEgi> which is also cheaper than the estimated 35mio/yeahr for the ship's operating cost 02:32 < ThomasEgi> or living somewhere in a desert or so. or syberia 02:32 < ThomasEgi> or antarctica 02:33 < ThomasEgi> there are many places that are favorable to open sea. 02:35 < ThomasEgi> talking about cool places to live http://www.geekologie.com/2012/05/instant-evil-villain-status-secret-subma.php 03:31 * Utopiah is looking for http://mitpress.mit.edu/catalog/item/default.asp?ttype=2&tid=12573 03:34 < Urchin> being underground is not exactly safe these days 03:35 < ThomasEgi> Urchin, what's unsave about it? 03:36 < Urchin> modern bunker busters 03:36 < ThomasEgi> ... good luck busting 2000m of granite :D 03:36 < Urchin> good luck digging that deep trough granite 03:37 < Urchin> and good luck not getting the ventilation jammed 03:37 < ThomasEgi> :) hehe. luck is not neccessary. i found a way to do so 03:37 < Urchin> or getting trapped inside 03:37 < Urchin> what would you use for power down there? 03:38 < ThomasEgi> different methods. 03:38 < ThomasEgi> at small scale at the beginning, just the excess water. 03:38 < ThomasEgi> later on deep-drills for geothermic stuff 03:38 -!- splicer [~ubuntu@c83-255-190-140.bredband.comhem.se] has quit [Ping timeout: 252 seconds] 03:38 < Urchin> sounds interesting 03:41 < ThomasEgi> as minimum requirement i need about 200 to 400 watts to start carving. which could be easily supplied by some water or solar power. 03:41 < ThomasEgi> the equipment is almost portaple. 03:41 < ThomasEgi> makes rather thing cuts tho. 04:04 -!- joshcryer [~g@unaffiliated/joshcryer] has quit [] 04:37 -!- chris_99 [~chris@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 05:27 -!- klafka1 [~klafka@c-24-6-19-91.hsd1.ca.comcast.net] has quit [Quit: This computer has gone to sleep] 05:38 -!- jmil [~jmil@c-68-81-252-40.hsd1.pa.comcast.net] has joined ##hplusroadmap 05:39 -!- sylph_mako [~mako@118-93-5-109.dsl.dyn.ihug.co.nz] has quit [Quit: Leaving] 06:36 -!- jmil [~jmil@c-68-81-252-40.hsd1.pa.comcast.net] has quit [Quit: jmil] 07:16 < dixiebassline> there is a conspiracy theory about a thing called a 'subterrene' ThomasEgi 07:17 < dixiebassline> its atomicly heated boring tip allows it to melt its way through the earth at a regular pace, fusing the walls solid as it travels 07:19 < ThomasEgi> dixiebassline, i know. it is not only a conspiracy 07:20 < ThomasEgi> it is a device that was actually build by russians. 07:20 < ThomasEgi> but.. reactor belw up :( 07:20 < ThomasEgi> my idea is not quite as radioactive. but comparebly hot. it thermal-cracks the rock open but only one tiny spot at a time. so i can manage with limited power input 07:23 < ThomasEgi> altho. not sure if subterrene is the thing build by russia. 07:24 < ThomasEgi> but the way it works sounds awfully familliar 07:27 -!- jmil [~jmil@2607:f470:8:3148:e984:451f:7fc1:804a] has joined ##hplusroadmap 07:28 < dixiebassline> instead of building a bunker, it would be quicker to locate one that is existing 07:28 < dixiebassline> theres an abandond cold war unit up the road from me 07:28 < dixiebassline> paid for by taxes.. i figure after zday it belongs to me anyway 07:29 < dixiebassline> albania is littered with bunkers 07:29 < dixiebassline> they dont know what to do with.. some of them are beach front 07:29 < dixiebassline> man... a beachfront concrete bunker on the med 07:29 < dixiebassline> albainia also banned religion a few years back 07:30 < dixiebassline> i think its gotten worse since then thoug 07:38 < ThomasEgi> hm. while bunkers sounds ok, they usualy are build at strategic important points. so in case of a country going to war, they'd raid your home first. 07:38 < ThomasEgi> that makes it a no-go for me 07:39 < dixiebassline> depends on where youre at and what you think the future holds 07:40 < ThomasEgi> hope for the best, prepare for the worst 07:41 < ThomasEgi> beeing paranoid, one can't be careful enough 07:48 < chris_99> what are you talking about? 07:48 < dixiebassline> build up a return on protection chart 07:48 < chris_99> WWIII? 07:49 < kanzure> a fortress of solitude. 07:49 < dixiebassline> its kind of like a debt snowball calc, but you put the most likely doomsday scenerios on it and figure out which ones are the cheapest and easiest to plan for 07:49 < dixiebassline> and go from there 07:49 < dixiebassline> somethings everyone should do, like store food and water enough for a few days 07:50 < dixiebassline> but you dont have to prepare for hurricanes in north dakota 07:50 < dixiebassline> unless you are just board 07:50 < dixiebassline> :P 07:50 < ThomasEgi> well in case of a geothermic or excess water powered cave system. you can even grow plants in there. 07:51 < dixiebassline> it would be quite a disaster to drive everyone underground to grow food 07:51 < chris_99> does anyone know of a site where you can purchase bioluminescent plankton 07:52 < dixiebassline> it might be a nice way to hide your productino from raiders though 08:07 -!- _F7_ [~forrestfl@safekick-americas-2.consolidated.net] has joined ##hplusroadmap 08:17 -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has quit [Ping timeout: 265 seconds] 08:58 -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has joined ##hplusroadmap 09:36 -!- dixiebassline is now known as Dr_Max 09:36 < kanzure> http://thepiratebay.se/torrent/5491409/Rosetta_Stone_V3_-_Arabic_(L1__L2__L3)_Complete 09:39 < Dr_Max> trying to get a govt job? 09:39 < Dr_Max> you did say we are nsa and cia friendly 09:44 -!- SDr [~SDr@apn-130-43-201-160.vodafone.hu] has joined ##hplusroadmap 09:44 -!- SDr [~SDr@apn-130-43-201-160.vodafone.hu] has quit [Changing host] 09:44 -!- SDr [~SDr@unaffiliated/sdr] has joined ##hplusroadmap 09:47 < kanzure> Dr_Max: haha, well. no.. the fbi is flying a bunch of us out to give some presentations next month 09:47 < kanzure> Dr_Max: and yashgaroth had the brilliant idea of answering an angry phone call in the middle of the workshop, in loud-angry arabi 09:47 < Dr_Max> very nice 09:48 < kanzure> *arabic 09:48 < Dr_Max> even better :P 09:48 < kanzure> another idea i'm considering is using twilio to call all of the agent's phones at once 09:48 < kanzure> *agents' 09:48 < Dr_Max> oh and throw in a jammer 09:48 < Dr_Max> and be like 'the lord givith' and the lord taketh away 09:49 < kanzure> i think i need something more benign though 09:49 < kanzure> like introducing myself in arabic to each agent 09:49 < Dr_Max> yeah 09:49 < kanzure> speak their language and such :P 09:50 < Dr_Max> yeah 10:06 -!- He||eshin [~talinck@cpe-174-101-208-182.cinci.res.rr.com] has joined ##hplusroadmap 10:06 < kanzure> oh wow i didn't know chminf-l went back to 1991 https://iulist.indiana.edu/sympa/arc/chminf-l 10:06 -!- _F7_ [~forrestfl@safekick-americas-2.consolidated.net] has quit [Ping timeout: 252 seconds] 10:07 -!- _F7_ [~forrestfl@safekick-americas-2.consolidated.net] has joined ##hplusroadmap 10:09 -!- Helleshin [~talinck@cpe-174-101-208-182.cinci.res.rr.com] has quit [Ping timeout: 252 seconds] 10:19 -!- Helleshin [~talinck@cpe-174-101-208-182.cinci.res.rr.com] has joined ##hplusroadmap 10:19 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has joined ##hplusroadmap 10:21 -!- He||eshin [~talinck@cpe-174-101-208-182.cinci.res.rr.com] has quit [Ping timeout: 260 seconds] 10:27 < kanzure> nmz787: yo we're all learning arabic for the workshop, you in? 10:28 < nmz787> hah hah 10:28 < nmz787> whats the first word we're learning? 10:29 < kanzure> dunno, any suggestions? 10:29 < nmz787> weapon 10:29 < nmz787> ?/ 10:29 < nmz787> protector 10:29 < nmz787> hah hah hah 10:31 < kanzure> ezproxy pricing info: http://web.archive.org/web/20010304090030/http://www.usefulutilities.com/ezproxy/pricing.shtml 10:31 < kanzure> "On the Linux, Solaris and Windows NT platforms, EZproxy costs US $495 per server, plus 7.5% sales tax for institutions in Arizona. There are no shipping or handling charges." 10:32 < kanzure> "EZproxy has been designed from its inception to be Y2K compliant." 10:35 < kanzure> oh neat, it's back.. 10:35 < kanzure> http://ezproxy.free-webmaster-resources.org/ 10:36 -!- SDr [~SDr@unaffiliated/sdr] has quit [] 10:52 -!- Dr_Max is now known as dixiebassline 10:56 -!- calango [~dnm@pdpc/supporter/active/calango] has joined ##hplusroadmap 10:58 -!- dixiebassline [~adam@75.105.14.63] has quit [Ping timeout: 265 seconds] 10:59 -!- gl00m [~adam@75.105.14.63] has joined ##hplusroadmap 11:13 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Ping timeout: 252 seconds] 11:26 -!- ThomasEgi [~thomas@pppdyn-44.stud-ko.rz-online.net] has joined ##hplusroadmap 11:26 -!- ThomasEgi [~thomas@pppdyn-44.stud-ko.rz-online.net] has quit [Changing host] 11:26 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap 11:37 < _F7_> arabic what what 11:45 < kanzure> hi gl00m 11:45 < gl00m> hello 11:45 * Mokbortolan_ gets gl00m a cheery set of curtains. 11:46 -!- gl00m is now known as dixiebassline 11:55 < strangewarp> Dale Carrico sucks 11:58 < kanzure> he's right though, futurism also sucks 11:58 < kanzure> ray kurzweil invented ocr 40 billion years ago, so what? 11:58 < kanzure> i don't see him in the commit logs in the tesseract repository 11:59 < kanzure> peter diamandis scammed insurance companies into funding the xprize, but that's about all he's known for. so what ? 12:00 < strangewarp> Carrico points at the claims disaster capitalists made about exponential economic growth, and claims it's isomorphic to claims abou technological growth 12:00 < strangewarp> That is silly 12:02 < strangewarp> Also I'm peeved because he's snagged Warren Ellis and Charles Stross, and turned them cranky 12:10 -!- strages_work [~c6740838@dev.throwthemind.com] has joined ##hplusroadmap 12:17 < _F7_> there was a point where warren ellis wasn't cranky? 12:18 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has quit [Quit: Leaving.] 12:18 < strangewarp> There was a point when he was visionary-cranky instead of doom-cranky 12:21 < _F7_> ah 12:22 < _F7_> Doktor sleepless is a good kind of doom cranky, though 12:22 < kanzure> "because who the heck would want to be doktor sleepyhead?" 12:23 < _F7_> paprika? 12:37 -!- jmil_ [~jmil@2607:f470:6:2:8ca5:aa9:daed:d31f] has joined ##hplusroadmap 12:41 -!- jmil [~jmil@2607:f470:8:3148:e984:451f:7fc1:804a] has quit [Ping timeout: 248 seconds] 12:41 -!- jmil_ is now known as jmil 12:46 -!- chris_99 [~chris@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 252 seconds] 13:23 < Mokbortolan_> sweet 13:23 < Mokbortolan_> I found a cheap replacement for the felt pads on my epoc 13:38 -!- chris_99 [~chris@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 13:42 -!- sylph_mako [~mako@118-93-5-109.dsl.dyn.ihug.co.nz] has joined ##hplusroadmap 13:42 < Mokbortolan_> http://www.directionsforme.org/index.php/directions/product/EYEPL/00011822654395 13:46 < kanzure> man i hate ieet/james hughes. 14:10 -!- _F7_ [~forrestfl@safekick-americas-2.consolidated.net] has quit [Quit: Computer has gone to sleep] 14:13 -!- sylph_mako [~mako@118-93-5-109.dsl.dyn.ihug.co.nz] has quit [Quit: Leaving] 14:28 < Mokbortolan_> yep, they work great 14:31 < Mokbortolan_> awesome, I get 50 for $6 14:31 < Mokbortolan_> suck it emotiv! 14:42 -!- archels [~foo@sascha.esrac.ele.tue.nl] has quit [Ping timeout: 245 seconds] 14:49 < kanzure> i think nmz787 is graduating today 14:49 -!- gl00m [~adam@75.105.14.63] has joined ##hplusroadmap 14:49 -!- dixiebassline [~adam@75.105.14.63] has quit [Read error: Connection reset by peer] 14:53 -!- archels [~foo@sascha.esrac.ele.tue.nl] has joined ##hplusroadmap 15:17 -!- jmil [~jmil@2607:f470:6:2:8ca5:aa9:daed:d31f] has quit [Quit: jmil] 15:18 < fenn> semax looks like an easy to make nootropic, it's a 7 segment peptide fragment of acth which stimulates BDNF, protects against stroke, and has other learning-enhancement effects 15:20 < fenn> "Some people just don´t approve of genetic engineering" what kind of objection is that 15:20 < fenn> on a transhumanist forum 15:20 < strangewarp> Some people just don't think that kind of objection is invalid 15:20 < strangewarp> obviously 15:22 < fenn> i'd expect the half life to be improved if the peptide were circularized 15:22 < fenn> right now they claim it lasts ~20 hours but with a half life of 4-5 minutes 15:25 < fenn> i love that you can completely specify a drug's structure with 7 letters: MEHFPGP 15:29 -!- _F7_ [~forrestfl@c-98-201-2-186.hsd1.tx.comcast.net] has joined ##hplusroadmap 15:40 < gl00m> trolling 15:40 < gl00m> obv 15:40 < gl00m> nice thing about transhumanisim is civilization is fucked anyway 15:40 < gl00m> so what if we make a few mistakes 15:41 < gl00m> might end up with a place like 'rapture' from bioshick 15:41 < gl00m> but prollt not 15:52 < kanzure> what? 15:52 < kanzure> go away 15:53 < strangewarp> zzzzzz 15:54 < gl00m> i was against h+ before i was for it 15:54 < gl00m> i adopted it as a sort of nihilism 15:55 < strangewarp> do note: the human brain tends to treat fictional examples as though they occurred somewhere for real, when they are in actuality complete fiction, because our minds are wired to think that everything we've seen has actually happened in some manner 15:58 < kanzure> gl00m: what do you mean "for it" 15:59 < fenn> pro-transhumanist, supposedly 15:59 < kanzure> but uh.. 15:59 < kanzure> i'm so tired of "pro" and "anti" advocacy crap 16:00 < kanzure> go advocate your advocacy plans somewhere else, even if it's doom-and-fear related 16:00 < fenn> d00m and gl00m 16:01 < kanzure> i was giong to say 'doom and gloom' but then realized it was a trap 16:01 < kanzure> *going 16:04 < gl00m> haha 16:06 < gl00m> i was just thinking of coming up with an advocacy plan. PATH - postanarchist transhumanist movement 16:06 < gl00m> but i didnt even know there were other ppl till yesterday 16:06 < Urchin> I've been transhumanist since I became aware of transhumanism 16:06 < kanzure> gl00m: advocacy is lame. you should just build the technologies and get on with it. 16:06 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has joined ##hplusroadmap 16:07 < gl00m> trufax 16:07 < kanzure> nmz787: happy fuck-school day 16:07 < gl00m> im into interfaces 16:07 < Urchin> gl00m: anarchism isn't part of the mainstream transhumanism since the '90s 16:07 < kanzure> Urchin: "mainstream" means what 16:07 < kanzure> where are you people making up all these words from 16:07 < gl00m> im from the internet 16:08 < Urchin> I'm just saying anarchists don't make up the core of transhumanists like they once did 16:08 < Urchin> that is my impression right now 16:08 < Urchin> I might be wrong 16:08 < kanzure> Urchin: this seems somewhat anarchist to me. http://www.maxmore.com/extprn3.htm 16:09 < gl00m> theyre not related 16:09 < gl00m> i dont actually like anarchists 16:09 < kanzure> Urchin: there are a lot of people who claim to be transhumanist, but if you look closely, what they really mean is "social media" 16:09 < gl00m> hence post anarchisim 16:09 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has quit [Client Quit] 16:09 < gl00m> its a temporary stage 16:09 < kanzure> what the hell is post-anarchism 16:09 < kanzure> blah 16:09 < gl00m> unless transhumanisim is applied and betters civlizaation to the point where ppl no longer need govt or other systems to regulate their behaviour 16:09 < Urchin> kanzure: max more is no longer all that popular 16:09 < kanzure> Urchin: he was never popular 16:10 < gl00m> i just made it up 16:10 < kanzure> Urchin: and i'm sorta disappointed in him 16:10 < gl00m> off the top of my head yesterday before i found this place 16:10 < gl00m> and realised this morning it was an acronym and decided to roll with it 16:10 < kanzure> maybe you should just say what you mean in the future, instead of post-anarchosynchronicies 16:10 -!- NonFish[ [~lurking@adsl-99-111-153-229.dsl.ipltin.sbcglobal.net] has joined ##hplusroadmap 16:11 -!- Guest87026 is now known as poptire 16:11 < Urchin> kanzure: Extropy Institute used to contain almost all of the transhumanist movement when he was at the head 16:11 < Urchin> the guy even knew FM-2030 16:11 < kanzure> fm-2030 isn't that interesting from what i can tell 16:12 < kanzure> also he's dead, so he fucked up hard 16:12 < Urchin> frozen 16:12 < Urchin> might get better in time 16:12 < Urchin> lol 16:12 < kanzure> i'm pretty sure it was revealed that the freezing process for the past 10 years was too damaging 16:13 < kanzure> well, i mean the past 10 years from 2005, not 2012 16:13 < Urchin> I haven't been keeping up with cryonics research 16:13 < Urchin> he might have been vitrified 16:13 < Urchin> freezing is a gamble 16:14 -!- NonFish_ [~lurking@adsl-99-111-153-229.dsl.ipltin.sbcglobal.net] has quit [Ping timeout: 256 seconds] 16:14 -!- NonFish[ is now known as NonFish_ 16:15 < chris_99> according to wikipedia it was vitrification 16:15 < Urchin> he's probably fine then 16:15 < Urchin> as much as possible 16:16 < Urchin> it's been a while since I read anything about that period 16:17 < gl00m> heh, Id heard huxly talk about remote controlled (raido reciever in the brain) chickens in the late 50s-60s. and someone just now showed me a book which had an anectdote about some delgado having a remote control bull in 65' that he could stop from charging with the press of a button 16:18 < gl00m> things like this make me wonder what kind of advancements have been made in the past 50-60 years 16:18 < kanzure> lots. 16:18 < kanzure> but not from people who consider themselves "advocates" 16:39 < kanzure> does anyone have a BLAST-like tool for binary blobs? 16:42 -!- chris_99 [~chris@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 16:43 < fenn> try searching for things based on compression distance 16:44 < kanzure> wouldn't that give false positives? 16:45 < fenn> i mean searching google 16:46 < kanzure> oh oh. 16:49 < fenn> there's also agrep, but that may not be what you want 16:49 < fenn> i'm guessing it's something to do with pokemon assembly 16:50 < kanzure> heh 16:50 < kanzure> https://github.com/kanzure/pokecrystal/blob/master/extras/comparator.py 16:50 < kanzure> i scan the pokered source code and extract functions, then read the bytes from the ROM, then find those in the other game that i have less-disassembled 16:50 < kanzure> most functions will be different because pointers will change 16:51 < kanzure> but this difference is only two bytes or something 16:51 < fenn> right 16:55 < kanzure> why haven't i purchased a reading of my exome yet 16:59 < JayDugger1> Where have you been shopping? 16:59 < kanzure> well it looks like 23andme has a beta waiting list thing 16:59 < kanzure> for $999 16:59 < JayDugger1> Oh, yeah, for the low low low price of $999 16:59 < kanzure> otogenetics.com is advertising one for $698 but i'm sure that's spam 17:00 < kanzure> genedx is advertising $1000/trio but what the heck is a trio 17:01 < JayDugger1> Would it provide you any actionable information? 17:01 < JayDugger1> (patient and two family members) 17:01 < JayDugger1> Assuming your insurance covers it. :) 17:02 < JayDugger1> And yes, it might tell you some condition or predisposition exists which you didn't suspect. 17:02 < JayDugger1> Have you done everything you can about those things you already know about? 17:03 < kanzure> well, i'm really unsure in general about when's the right time to splurge on genomic information about myself 17:03 < JayDugger1> Fair enough. 17:03 < kanzure> the most important factor that i consider is that my famiy members don't have any backups of their genetic data 17:03 < JayDugger1> Hm? 17:03 < kanzure> i would really really like to have samples from my living relatives to compare against 17:03 < JayDugger1> I don't understand what you mean--oh, now I do. 17:04 < JayDugger1> Well...perhaps it would be better to first, share your 23andMe results with them. 17:04 < JayDugger1> Second, offer to gift them 23andMe's basic test. 17:04 < kanzure> i should probaby just pay for them to do 23andme, since they haven't yet 17:04 < JayDugger1> Yeah, pretty much. 17:05 < JayDugger1> If you've any family members with genealogy as a hobby, 23andMe will interest them from that angle. 17:05 < JayDugger1> It worked on my Dad, for instance. 17:06 < JayDugger1> My sister and I signed him up for the National Genographic Project, which interested him because he does genealogical research as a hobby. 17:06 < JayDugger1> As for splurging--cheaper than a year's worth of first-run video games, I think? 17:07 < kanzure> yeah, it's not much of a splurge now is it? 17:07 < kanzure> but, the costs are also falling anyway - or they are supposed to (haha, yeah right) 17:07 < JayDugger1> I waited for the sales, and then offered it to family members. Only my wife took me up on it. 17:07 < kanzure> so in 5 years, i will feel stupid for having spent $900 in 2012, vs. $10 in 2017 17:07 < kanzure> (i will also feel stupid if all of my family is dead by then, and i don't have any data to work with) 17:08 < JayDugger1> Well, yeah. 17:08 < kanzure> ((i'd probably resort to graverobbing, but let's not give our friends in suits anything else on me)) 17:09 < JayDugger1> So let me make this suggestion. Work on convincing your oldest family members now. As you convince people to make the tests, prefer to do it from oldest to youngest, 17:09 < JayDugger1> and where-ever you fall in that ranking, get your test too. 17:10 < JayDugger1> Meanwhile, work on the usual doctor's advice: eat right, avoid stress, exercise, etc. 17:10 < JayDugger1> And take good care of your teeth. 17:10 < kanzure> what does that have to do with exome sequencing? 17:10 < kanzure> sorry, you lost me 17:10 < JayDugger1> If you find from genetic testing that you might have a particular test, act on it only in proportion to the seriousness of the risk. 17:11 < JayDugger1> might have a particular predisposition rather, sorry--still on coffee cup #1. 17:11 -!- Jora [~Jora@24-196-83-11.dhcp.mdsn.wi.charter.com] has joined ##hplusroadmap 17:11 -!- Jora [~Jora@24-196-83-11.dhcp.mdsn.wi.charter.com] has quit [Changing host] 17:11 -!- Jora [~Jora@unaffiliated/jora] has joined ##hplusroadmap 17:11 < JayDugger1> This assumes you have the tests done for health, and not for geek cred. :) 17:13 < kanzure> there's also another reason- just curiosity 17:13 < JayDugger1> Oh. 17:13 < kanzure> there's no particular health reason that i need to know my exome, or my SNPs, or anything else for that matter 17:13 < JayDugger1> Right. You did write "splurge." 17:13 < JayDugger1> Not until after you've plucked all the "low-hanging fruit," so to speak. 17:13 < kanzure> although, it's entirely possible that i have a high likelihood of getting addicted to cocaine, so that would be cool to know about 17:14 < JayDugger1> Yeah, if you have a pulse, there's a good chance you're at risk, yes. :) 17:15 < JayDugger1> As for splurging, whenever it fits your budget. If your health insurance will pay for it, even better. 17:20 < fenn> s/cocaine/adderall/ 17:20 < JayDugger1> Ditto my earlier comment. 17:21 < fenn> my opinion, best to get your own SNP's now and wait til it's trivially cheap for the rest of the family 17:21 < fenn> you have all of your own genetic information 17:22 < kanzure> the family death factor seems more immediate, i'm unlikely to lose access to my genes 17:22 < fenn> actually, there's a strong trend towards making cool things illegal 17:22 < JayDugger1> Good point, fenn. 17:22 < fenn> so you might "lose access" in the sense that companies like 23andme will no longer exist 17:22 < fenn> that is why i got sequenced 17:23 < kanzure> 23andme is going down the shitter anyway (last i heard they were having problems with becoming profitable) 17:23 < kanzure> not sure how true that is. i should probably not say that. 17:23 < fenn> SELL! SELL! 17:23 < fenn> no wait, BUY! 17:24 < JayDugger1> http://www.personalgenomes.org 17:24 < kanzure> pgp? i'm pretty sure jason bobe hates me, and that's why my application never went through 17:25 < JayDugger1> I don't know whether you'd get any data back. I think so... 17:26 < JayDugger1> Eh...use a fake name. 17:26 < fenn> anyone ever talked to steve fowkes? 17:26 < JayDugger1> Probably easier said than done. 17:26 < kanzure> JayDugger1: didn't they recently upload the data to amazon? 17:26 < kanzure> or was that the 1000 genomes project 17:27 < kanzure> maybe that was a different group 17:27 < fenn> he wrote a popular book about nootropics and maintained newsletters and a nootropics help line for several years 17:27 < JayDugger1> I hadn't heard of that. 17:27 < kanzure> here we go 17:27 < kanzure> JayDugger1: https://groups.google.com/forum/?fromgroups#!topic/diybio/vhy4ghUWCGM 17:27 < kanzure> fenn: a help line? like a phone line? 17:27 < fenn> yeah 17:28 < kanzure> "Apparently in the next few months, there will around a hundred people with maintained human cell lines, and their full genomic sequences will soon follow (reference: http://chirpstory.com/li/6877 ). To paraphrase: PGP will sequence about a dozen human genomes per month." 17:28 < kanzure> JayDugger1: if you scroll down in that thread you will also see some links i dropped to the 1000 genomes project data dump on amazon aws 17:28 < JayDugger1> Fenn, I hadn't heard of Mr. Fawkes until now. 17:29 < fenn> "CERI is currently in hibernation mode, due to financial constraints. We would very much like to resume services. If you appreciate the quality and independence of our efforts and know somebody with philanthropic leanings, please make the introduction." 17:29 < fenn> oddly they are located in menlo park, home of the gigabucks 17:29 < kanzure> fenn: chris peterson knows him 17:29 < kanzure> and he went to or spoke at personalized life extension conference 17:29 < kanzure> but that's the only data i have on him 17:30 < fenn> currently reading ceri.com 17:30 < fenn> seems to be as much about anti-aging as nootropics 17:31 < kanzure> the anti-aging crowd is really weird to figure out 17:31 < kanzure> like, where are all these russian publications coming from? 17:32 < fenn> maybe the russian government has bought into the medical tourism strategy 17:33 < fenn> nobody buys nuclear bombs anymore :P 17:33 < kanzure> i keep trying to but they won't take my money 17:35 < JayDugger1> Shouldn't that be, "they keep taking my money but they won't deliver?" 17:50 -!- sylph_mako [~mako@wireless-nat-7.auckland.ac.nz] has joined ##hplusroadmap 17:56 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Remote host closed the connection] 18:23 -!- joshcryer [~g@c-75-70-40-195.hsd1.co.comcast.net] has joined ##hplusroadmap 18:23 -!- joshcryer [~g@c-75-70-40-195.hsd1.co.comcast.net] has quit [Changing host] 18:23 -!- joshcryer [~g@unaffiliated/joshcryer] has joined ##hplusroadmap 18:26 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has joined ##hplusroadmap 18:27 < brownies> fenn: eh? link to nootropics book? 18:29 < fenn> i havent read it: http://www.amazon.com/Smart-Drugs-II-Drug-Series/dp/0962741876 18:30 < fenn> dammit where's gigapedia gone off to again 18:31 < kanzure> i think you mean libgenesis 18:31 < fenn> sum | uniq 18:32 < kanzure> worse ui, larger dataset i think 18:35 < brownies> clearly all those smart drugs they took did not help them design a book cover that wasn't hideous 18:35 < fenn> that was at http://free-books.dontexist.com/ right? 18:35 < kanzure> fenn: yes 18:35 < fenn> well it's gone too 18:36 < kanzure> you can track him by his reddit username 18:36 < kanzure> http://www.reddit.com/user/bookwarrior 18:37 < kanzure> might be a backup at http://gen.lib.rus.ec/ 18:37 < fenn> i see 18:37 < kanzure> and you can complain here http://gen.lib.rus.ec/forum/ 18:38 < fenn> what am i supposed to complain about? 18:38 < kanzure> gigapedia failing to exist? i don't know 18:38 < fenn> "your free illegal service sucks! wah!" 18:38 < brownies> and it was published in 1993 =/ 18:38 < kanzure> well we could accost jrayhawk until he agrees to make a mirror 18:39 < brownies> so it's only 19 years out of date! 18:39 < fenn> excellent 18:46 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has quit [Quit: Leaving.] 18:47 -!- calango [~dnm@pdpc/supporter/active/calango] has quit [Quit: Leaving] 18:52 < docl> kanzure: I used our discussion of misuse of evolution the other day in a lesswrong article, which has now been promoted on Main. 18:56 < gl00m> Ketamine Improves Bipolar Depression Within Minutes 18:56 < kanzure> docl: hey you're not allowed to use my rants to advance the acclaim of lesswrong :| 18:56 < kanzure> well, i guess i never explained my particular dislike of lesswrong to you 18:56 < docl> oh really? 18:56 < kanzure> so you're probably not aware. also i'm slightly kidding, i'm happy for you :\ 18:57 < docl> :) 18:57 < kanzure> is this it? http://lesswrong.com/lw/coo/avoid_inflationary_use_of_terms/ 18:57 < docl> yep 18:57 < sylph_mako> kanzure, is your dislike expounded somewhere we can all read it? 18:58 < kanzure> docl: you should add "consciousness" and "mind" and "reality" 18:58 < kanzure> well, no, don't add "reality" 18:58 < kanzure> sylph_mako: no, i currently carry a lot of anti-siai debt that i will need to make payments towards one day with actual writing or something 18:58 < sylph_mako> Also have you verbalized your problem with purely philosophical discussions? Because I'm about to verbalize mine and you might save me some effort. 19:01 -!- Juul [~Juul@171.65.196.113] has joined ##hplusroadmap 19:01 -!- Juul [~Juul@171.65.196.113] has quit [Client Quit] 19:03 < kanzure> sylph_mako: mostly it's my lack of interest in babysitting everyone here through their personal identity crises, or having to fight back their horribly unconsidered philosophies 19:03 < kanzure> i don't claim to have "perfect" philosophy either but i do like to think of myself as somewhat careful 19:04 < kanzure> but also because there's so much other work we could be doing than debating the latest edition of IEET monthly or some crap like that 19:04 < sylph_mako> Careful? I'm glad to hear that. 19:05 < kanzure> almost everyone goes into this horrible identity crises when they consider brain scanning, at some point it's tiresome 19:05 < kanzure> surely we don't have to tolerate that forever in here? 19:06 < strangewarp> I saw that LessWrong article earlier, and loved it 19:07 < docl> :) 19:07 < strangewarp> Always good when they make an actually useful point 19:08 < kanzure> however, if you really think there's a relevant philosophy discussion, you could just privately ask me or something, so i don't go ballistic 19:10 < sylph_mako> Hehehehe 19:10 < kanzure> i can imagine various exceptions to the no philosophy rule, like, say you have a paper that proves consciousness exists, that might be worth looking at 19:11 < kanzure> *exists, /that/ might be worth looking at 19:11 < kanzure> (i have recently noticed that a lot of my tonal implications have been dropped from my messages?) 19:12 < sylph_mako> So, the rule is that we must first ask kanzure whether the theory we wish to discuss is tired? 19:12 -!- strages_work [~c6740838@dev.throwthemind.com] has quit [Quit: CGI:IRC (Session timeout)] 19:13 < kanzure> sylph_mako: the rule is to use good judgement 19:15 < docl> good rule! 19:16 < kanzure> and to use better spelling than me (judgment) 19:19 -!- devrandom [~devrandom@gateway/tor-sasl/niftyzero1] has quit [Remote host closed the connection] 19:25 -!- yashgaroth [~f@cpe-66-27-117-179.san.res.rr.com] has joined ##hplusroadmap 19:29 -!- devrandom [~devrandom@gateway/tor-sasl/niftyzero1] has joined ##hplusroadmap 19:29 < kanzure> yashgaroth: http://thepiratebay.se/torrent/5491409/Rosetta_Stone_V3_-_Arabic_ 19:29 < yashgaroth> heh yeah I've been catching up on the logs 19:30 < yashgaroth> my futile attempts at mandarin are occupying my language-learning hours 19:34 < kanzure> i wonder what the minimum percent variation in muscle mass you're supposed to be able to notice is 19:35 < yashgaroth> aside from the crude 'stick a measuring tape around the widest part' I'm not sure there's a good gauge 19:36 < kanzure> well i meant perceptual, without measuring sticks 19:36 < kanzure> erm, uh. 19:36 < kanzure> somethingprioception 19:36 < yashgaroth> myoception or something, I never took greek 19:38 < yashgaroth> oh while I'm on the logs, fenn: circularizing a peptide that short would extend the half-life greatly but would also block it from folding, which would make it useless for doing whatever it'd do in its native conformation 19:38 < yashgaroth> circular peptides are great if you design them from the get-go to be circular, otherwise it's not worth the hassle 19:42 < brownies> ok, well, now i have to know 19:42 < brownies> what the hell sort of identity crisis would come up when someone considers brain scanning? 19:42 < kanzure> hilarious examples commencing 19:42 < kanzure> there's the classic "if you are copied during your sleep, atom-by-atom, and you wake up the next morning, you're really your son!" arguists 19:43 < kanzure> others are troubled by the fact that they go to sleep and wake up not exactly atomically the same 19:43 < yashgaroth> if there's two copies of you, which "one "is "you""" 19:43 < sylph_mako> Both, I am now two people. Not that I'm discussing this. 19:43 < sylph_mako> No no. 19:44 < kanzure> sylph_mako: go ahead, but i will stubbornly refuse to believe that you are two people 19:44 < brownies> those are pretty hilarious 19:44 < kanzure> brownies: others like to trot out the "quantum teleporation" examples 19:45 < brownies> what happens there? 19:45 < brownies> oh, that's the hypothetical one where your'e dstroyed in one place and an exact copy is created elsewhere? 19:45 < kanzure> if you get turned into atomic soup and teleported to another location, then reassembled, to your original self it will look like you're no longer your self, or something 19:45 < kanzure> yes 19:45 < gl00m> or its alternate realities all the way down 19:46 -!- docl [~luke@unaffiliated/docl] has quit [Read error: Connection reset by peer] 19:46 < yashgaroth> I've booked a berth on the ship of theseus, myself 19:46 < kanzure> gl00m: you mean hermit turtle masters all the way down 19:46 < gl00m> all the way up too 19:46 < gl00m> apparently 19:47 < brownies> a turtle tower? 19:47 < kanzure> Kamesenryuu Kitsui Shugyou 19:47 < kanzure> 亀仙流きつーい修業 19:48 < yashgaroth> the google search on that was interesting 19:49 < kanzure> just a turtle's philosophy 19:49 < brownies> anyway, if i could copy myself atom-by-atom, we'd write so much fucking code 19:49 < yashgaroth> the only result was some russian malware shit, at least for the transliterated text 19:49 < brownies> oh! we could sleep in shifts, so that our coding output is always constant 19:50 < kanzure> brownies: 2x code output? that doesn't sound like the best use of time 19:50 -!- srangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has joined ##hplusroadmap 19:52 -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has quit [Ping timeout: 245 seconds] 19:52 -!- srangewarp is now known as strangewarp 20:02 -!- klafka1 [~klafka@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap 20:07 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has joined ##hplusroadmap 20:10 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has quit [Client Quit] 20:16 < kanzure> klafka1: hi 20:16 < klafka1> hey kanzure 20:16 < klafka1> can't get my mcmc sampler to work! 20:17 < kanzure> brownies: you like to pretend to know how to write good mcmc samplers, right? 20:19 < brownies> kanzure: if you're referring to the time when i taught you how to write one because i know how... -_- 20:19 < brownies> anyway, i'm rusty, but i can take a look. 20:19 < klafka1> https://gist.github.com/2840728 20:19 < kanzure> brownies: yep i am :P 20:19 < brownies> your lack of spacing after your commas angers me 20:19 < klafka1> lol 20:20 < klafka1> i guess i failed PEP that way 20:20 < klafka1> i think PEP allows for either way actually 20:20 -!- srangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has joined ##hplusroadmap 20:22 < klafka1> so i modified it to include the distribution i input and the empirical distribution from 10,000 samples 20:22 -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has quit [Read error: Operation timed out] 20:22 -!- srangewarp is now known as strangewarp 20:22 < brownies> ok, i see, self.dist is your distribution? 20:23 < klafka1> yes 20:23 < klafka1> no 20:23 < klafka1> er 20:23 < klafka1> sorry 20:23 < brownies> .... 20:23 < klafka1> yes - self.dist is my distribution 20:23 < brownies> see what happens when you use terrible variable names -_- 20:23 < brownies> ok 20:23 < klafka1> prop_dist is my proposal distribution - the uniform distribution 20:23 < brownies> over a 2-dimensional space the size of self.range[1] 20:23 < klafka1> in this case it's uniform 1/16 20:24 < klafka1> yes 20:24 < brownies> whatever the hell self.range is... 20:24 < brownies> ok 20:24 < klafka1> so i'm looking at binary vectors of length 2 20:24 < klafka1> oh shit 20:24 < klafka1> duh 20:24 < klafka1> no nvm that is right 20:25 < klafka1> the proposal distri bution should be 1/4th 20:25 < klafka1> not 1/16th 20:25 < klafka1> and it is in fact that 20:25 < klafka1> since there are 4 possible states for a 2 length binary vector 20:25 < klafka1> idk why the hell i said 1/16th - anyway 20:26 < brownies> ok so 20:26 < brownies> given that your code is extremely confused about what its doing 20:26 < klafka1> is it? 20:26 < brownies> can you just explain succinctly what you want to do? 20:26 < brownies> sample = proposal; proposal = randint(self.range[0],self.range[1],self.size) 20:27 < brownies> well, anyway, what are you trying to do? 20:28 < klafka1> i'm trying to write a sampler for arbitrary discrete probability distributions using the uniform distribution as the proposal distribution 20:28 < klafka1> in this test case i'm wanting to sample binary vectors of length two with probabilities represented in a 2x2 matrix 20:29 < klafka1> so i defined the proposal distribution to be uniform (in this case 1/4). I generate the first sample point from randint - a uniform sampler 20:30 < klafka1> until i reach the number of samples I calculate the (acceptance probability) (named erroneously proposal probability, 20:31 < klafka1> if acceptance probability of sample >= 1 ACCEPT otherwise accept with probability - acceptance_probability, 20:31 < klafka1> set the proposed point to the current point, and generate a new proposal point 20:33 < brownies> i see 20:36 < klafka1> http://www.youtube.com/watch?v=_TSIhOyXk5M 20:37 < brownies> (i'm pondering your code) 20:37 < brownies> you didn't even use the burn_in variable? 20:37 < brownies> it almost looks like you're trying to run simulated annealing, but you're missing a couple salient features of that approach... 20:38 < klafka1> burn-in is something i would implement once i got the base line working 20:38 < klafka1> many people would argue that burn-in is pointless 20:38 < klafka1> and also that if i'm generating 10,000 samples for a state space of size 4 i should be able to converge for sure 20:39 < brownies> converge to what, exactly? that's what's unclear about this code 20:40 < klafka1> well by detailed balance the samples generated by the markov chain should be represented of the distribution self.dist 20:40 < klafka1> *representative 20:40 < klafka1> i mean that's the point of MCMC 20:46 < brownies> so you have a distribution... and you're trying to produce 10,000 samples from that distribution? 20:46 < brownies> what does self.dist return when you give it a vector? the probability of the mystery distribution producing that vector? 20:47 < brownies> the line where you calculate proposal_prob is suspicious to me 20:51 -!- sylph_mako [~mako@wireless-nat-7.auckland.ac.nz] has quit [Quit: Leaving] 20:53 < klafka1> i'm actually generating a Markov chain composed of 10,000 samples some of which will eventually be from that distribution 21:43 -!- Jora [~Jora@unaffiliated/jora] has quit [Quit: Leaving] 21:59 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has joined ##hplusroadmap 22:20 < kanzure> yashgaroth: blah i am missing plans for doing a reasonable hplc 22:21 < yashgaroth> well shucks 22:21 < kanzure> *poke* 22:21 < yashgaroth> I'm not a mechanical engineer 22:21 < nmz787> fenn still around? 22:21 < kanzure> fenn: pingo 22:25 < nmz787> kanzure: PM 22:28 < yashgaroth> all you reeeeally need is a peristaltic pump that can do maybe 0.1-1.0 ml/min, a way to inject sample into that, and inline pressure & UV sensors...and temperature control, conductivity meter, degasser 22:29 < nmz787> cant HPLC be found on CL or ebay? 22:29 < yashgaroth> indeed, and it's probably way easier to just buy one from the 80's than building one from scratch 22:29 < nmz787> the injectors are pretty cool 22:30 < yashgaroth> hells yeah they are 22:30 < nmz787> it rotates fludic paths to change from buffer to sample injection going to the column, then back again to begin separation 22:32 < yashgaroth> I've only had to manipulate the larger FPLC ones, but yeah it's basically just a rotor with holes running through 22:54 -!- sylph_mako [~mako@118-93-5-109.dsl.dyn.ihug.co.nz] has joined ##hplusroadmap 23:24 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has quit [Quit: Leaving.] 23:25 -!- nmz787 [~Nathan@cpe-67-242-177-23.rochester.res.rr.com] has joined ##hplusroadmap 23:33 < strangewarp> PZ Meyers sucks 23:34 < kanzure> probably 23:36 < strangewarp> He claims to be a rationalist, but he makes a beginner-level mistake by assuming transhumanism is a silly cult because it shares several attributes with silly cults 23:36 < yashgaroth> link plz 23:37 < strangewarp> This may take a second - it was an old blog post, from before I stopped reading him 23:37 < strangewarp> I was just reminded about it, by seeing some fellow atheists gush with respect for him 23:40 * strangewarp reads them quickly to make sure he has rememberedthem properly 23:43 < strangewarp> Oh hm 23:43 < strangewarp> Maybe I'm thinking of one of the Skepticblog people 23:43 < strangewarp> Okay, flipping out now, who wrote these blog posts I'm remembering 23:45 < sylph_mako> I vaguely recall their existing. 23:45 < sylph_mako> I remember blue on white. Was the author a technologist of some kind? 23:46 < joshcryer> strangewarp, must be another deathist. 23:46 < joshcryer> :) 23:47 < joshcryer> I remember one where a "rationalist" atheist talked about a discussion he had with his daughter who was, at a child-like level, arguing against death. 23:47 < joshcryer> (vague recollections, but children tend to express distaste for death that adults somehow irrationally accept) 23:47 < strangewarp> sylph_mako: I think it was by one of those celebrity-scientist types, who all gradually fell off my blogroll one by one for being obnoxious or boring 23:49 < strangewarp> joshcryer: Ha, and I'm assuming this so-called "rationalist" used the fact that a naive child hates death as an argument that non-naive people should love death? 23:50 < joshcryer> strangewarp, it's been so long, but he basically used a "death is change" argument. 23:50 < strangewarp> urgh 23:58 < strangewarp> Oh my god, I may have had faulty memories 23:58 < joshcryer> You find it? 23:59 < joshcryer> Now I'm going to have to find the one I remember. 23:59 < strangewarp> Meyers has some posts on transhumanism/singularity stuff, but nothing as obnoxious as what I remember reading --- Log closed Thu May 31 00:00:26 2012