--- Log opened Mon Jun 11 00:00:37 2012 00:10 < sylph_mako> Does anyone remember the name of that city which didn't appear to be built for humans? 00:10 < Utopiah> Brasilia? 00:11 -!- Coornail_ is now known as Coornail 00:12 < strangewarp> The Chaco Canyon pueblo complexes? Although it was probably a forced-tribute architectural project extorted out of slaves.. 00:12 < sylph_mako> -_- no. Like. Ancient ruins; unnavigable without climbing gear, apparently by design. Might be a crock but I have a WHACKY THEORY I want to investigate if it's not. 00:12 < strangewarp> Oh, not Chaco Canyon then 00:13 < sylph_mako> That was in reply to an earlier comment. 00:13 * strangewarp nods 00:14 < strangewarp> Chaco Canyon is mostly flat though, which is why I say it can't be that :p 00:26 < Utopiah> Machu Picchu? 00:35 < sylph_mako> seems unlikely. 00:36 < sylph_mako> At least most of it is hospitable. 00:37 < strangewarp> If it's Mesa Verde, they already probably figured it out - it was built as a last line of defense against a rampaging band of Aztecs, probably by the descendents of the people who were probably enslaved to build the Chaco Canyon pueblo complexes 00:39 * strangewarp lots of "probably" caveats, since there is still some controversy I think 01:30 -!- NonFish_ [lurking@adsl-108-79-213-97.dsl.ipltin.sbcglobal.net] has quit [Read error: Connection reset by peer] 01:30 -!- NonFish_ [lurking@adsl-108-79-213-97.dsl.ipltin.sbcglobal.net] has joined 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[~neuro@unaffiliated/neurosys/x-283974] has joined ##hplusroadmap 10:56 -!- Mariu [Jimmy98@89.41.57.33] has joined ##hplusroadmap 11:19 -!- gl00m [~adam@75-105-14-63.cust.wildblue.net] has joined ##hplusroadmap 11:26 < delinquentme> anyone happen to have the research paper on whatever process was used to get insulin from microbes? 11:26 < delinquentme> was this written about in a research paper? 11:30 < chris_99> are you thinking of that video a while back 11:30 < chris_99> because what he did wasn't actually creating insulin 11:30 < chris_99> it was an 'art' project apparently 11:46 -!- Mokbortolan_ [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has joined ##hplusroadmap 11:55 -!- upgrayeddd [u2969@gateway/web/irccloud.com/x-vanpbsqhhhgwfneb] has joined ##hplusroadmap 12:03 < delinquentme> chris_99, I can think of one video which was on jalopnik or something that was makin prozack or something 12:03 < delinquentme> Is there some hello world for novel compound creation in yeast? 12:04 < chris_99> oh yeah it was prozac 12:04 < chris_99> i'd be interested in that too delinquentme 12:04 < chris_99> just bought a book about yeast 12:04 < delinquentme> chris_99, I've got some in my freezer :D 12:05 < chris_99> for what? 12:05 < delinquentme> and a bunch of 96 well microplates 12:05 < chris_99> ooh cool 12:05 < delinquentme> baking I think lol 12:05 < chris_99> nice, i do brewing 12:05 < delinquentme> you know about the iGem group that put resveratrol into beer right? 12:05 < chris_99> nope 12:05 < delinquentme> google that shit! 12:06 < delinquentme> i think it was last years iGem 12:06 < chris_99> very interesting, so it extends the life of yeast? 12:06 < delinquentme> bewm! 12:06 < delinquentme> http://www.iptv.org/exploremore/ge/what/insulin.cfm 12:07 < chris_99> cool 12:25 <@kanzure> update: walnut creek sucks 12:25 < jrayhawk> i bet it's not even made of walnuts :mad: 12:25 <@kanzure> in a walut up a creek without a paddle 12:25 <@kanzure> .. i a walutshell 12:25 <@kanzure> *in a walnutshell 12:26 <@kanzure> i kept trying to think of brilliant walnut/creek jokes, but i've got nothing yet 12:26 <@kanzure> but it's def. nice to see the FBI go all out on a 1-star hotel 12:28 < jrayhawk> the GSA took all the nice ones 12:29 <@kanzure> http://images.memegenerator.net/instances/21869192.jpg 12:41 -!- SDr [SDr@unaffiliated/sdr] has joined ##hplusroadmap 12:49 -!- eudoxia [~eudoxia@r186-52-179-25.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 13:01 -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Ping timeout: 245 seconds] 13:04 -!- devrandom [~devrandom@gateway/tor-sasl/niftyzero1] has quit [Remote host closed the connection] 13:09 -!- eudoxia [~eudoxia@r186-52-179-25.dialup.adsl.anteldata.net.uy] has quit [Ping timeout: 256 seconds] 13:10 -!- devrandom [~devrandom@gateway/tor-sasl/niftyzero1] has joined ##hplusroadmap 13:11 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has quit [Remote host closed 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<@kanzure> lolz it's just raining money in SF isn't it? 13:36 <@kanzure> (nailed another contract; haven't been here for long) 13:47 <@kanzure> in other news: turtles fall out of love after 115 years http://news.discovery.com/animals/tortoise-couple-breaks-up-120611.html (yes i'm kidding, i don't expect any of you to click) 14:23 < _Sketch_> kanzure: What do you do for work? 14:24 <@kanzure> sit around naked all day 14:25 <@kanzure> mostly software contracting- web apps, mobile apps, the works 14:26 < _Sketch_> aha. 14:26 < _Sketch_> Dangit. Is all mind-mapping software in Java? :( 14:27 <@kanzure> mind-mapping software tends to suck immensely 14:27 < _Sketch_> WikkaWiki is PHP! yaaaaay 14:27 < _Sketch_> So it would seem, kanzure. 14:28 < _Sketch_> I could write my own... amazing, programming is like having superpowers. ;) 14:29 < _Sketch_> But I'm pressed for time, so searching is way easier. Hee. 14:37 <@kanzure> i don't think php is the right solution for your problem 14:37 <@kanzure> but i you are married to php, i think semanticmediawiki has some silly mindmapping mod/plugin thing 14:37 <@kanzure> *if you are 14:38 -!- sylph_mako [~mako@149.66.252.27.dyn.cust.vf.net.nz] has joined ##hplusroadmap 14:42 -!- sylph_mako [~mako@149.66.252.27.dyn.cust.vf.net.nz] has quit [Ping timeout: 248 seconds] 14:44 < _Sketch_> 'yaaaay' being entirely sarcastic. 14:48 -!- sylph_mako [~mako@149.66.252.27.dyn.cust.vf.net.nz] has joined ##hplusroadmap 14:50 <@kanzure> someone was asking for the current location of a library genesis.. 14:50 <@kanzure> http://libgen.info/ 15:06 <@kanzure> "Wow, I love my room btw. I've got a sliding glass door that leads out directly to the pool area. I'm thinking after-hours get togethers. :-)" 15:06 -!- _Sketch_ [~Sketch@71-81-148-153.dhcp.stls.mo.charter.com] has quit [Read error: Connection reset by peer] 15:06 <@kanzure> 1) is he coming on to me 15:07 <@kanzure> 2) why does he get the cool room >:( 15:07 -!- _Sketch_ [~Sketch@71-81-148-153.dhcp.stls.mo.charter.com] has joined ##hplusroadmap 15:16 -!- SDr [SDr@unaffiliated/sdr] has quit [Remote host closed the connection] 15:17 -!- Magic-Smoke [~Magic-Smo@h254.158.185.173.static.ip.windstream.net] has joined ##hplusroadmap 15:17 -!- Magic-Smoke [~Magic-Smo@h254.158.185.173.static.ip.windstream.net] has quit [Client Quit] 15:18 < chris_99> do you use Flask kanzure? 15:18 -!- srangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has joined ##hplusroadmap 15:19 -!- strages_shop [~strages@256.makerslocal.org] has joined ##hplusroadmap 15:22 -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap 15:22 -!- ybit2 [~ybit@131.252.130.248] has joined ##hplusroadmap 15:27 -!- Magic-Smoke [~Cody@h254.158.185.173.static.ip.windstream.net] has joined ##hplusroadmap 15:29 -!- |G|00M| [~adam@75-105-14-63.cust.wildblue.net] has quit [Ping timeout: 240 seconds] 15:29 -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has quit [Ping timeout: 248 seconds] 15:29 -!- ybit [~ybit@unaffiliated/ybit] has quit [Ping timeout: 248 seconds] 15:29 -!- srangewarp is now known as strangewarp 15:30 -!- drazak [~ahdfadkfa@drazak.net] has quit [Ping timeout: 240 seconds] 15:30 -!- Tukotih [~Tukotih@81-231-85-111-no39.tbcn.telia.com] has quit [Quit: Leaving.] 15:30 -!- |G|00M| [~adam@75.105.14.63] has joined ##hplusroadmap 15:32 <@kanzure> chris_99: sometimes, but not on anything in production at the moment 15:32 -!- strages_home [~strages@adsl-98-81-21-7.hsv.bellsouth.net] has quit [Ping timeout: 269 seconds] 15:32 -!- drazak [~ahdfadkfa@drazak.net] has joined ##hplusroadmap 15:32 < chris_99> aha cool, i've just started using it, i've had to give up on Play unfortunately do to memory issues 15:32 <@kanzure> Magic-Smoke: are you the magic smoke that keeps escaping my resistors? 15:32 <@kanzure> chris_99: give django a shot 15:33 <@kanzure> chris_99: and then repent and learn rails/sinatra anyway 15:33 < chris_99> django/rails are too heavy weight for what i need 15:33 <@kanzure> have you used them before? 15:33 -!- strages_home [~strages@adsl-98-81-21-7.hsv.bellsouth.net] has joined ##hplusroadmap 15:33 < chris_99> i've looked into them 15:33 < chris_99> but not used them 15:37 <@kanzure> the biggest shock to me when i picked up rails was how many more gems and plugins there were than for django. 15:37 <@kanzure> flask is more similar to sinatra, of course 15:39 < chris_99> because i've only got a limited amount of ram i want something that's as small as possible really 15:42 <@kanzure> jrayhawk: so, i made a merge commit in a feature branch a few weeks ago, committed a bunch of new stuff, and now want to rebase on master instead of merging things around 15:42 <@kanzure> jrayhawk: how do i correct this? i have to "undo" my merge from a thousand commits ago? 15:42 <@kanzure> or is the solution something else 15:57 < jrayhawk> well, the 'i don't have a particular reason to give a shit about the history' approach is to revert it 16:00 < jrayhawk> if this is an educational exercise or an excersize in pedanticism you can rebase or filter-branch depending on exactly what it is you want 16:00 <@kanzure> i'd like to keep the work i did, heh 16:01 <@kanzure> basically i want to pretend like i was rebasing on top o master the entire time, instead of that nasty merge commit in the iddle. 16:01 < jrayhawk> yeah, that's rebase's job 16:01 <@kanzure> someone else requested this; i convinced him that this isn't necessary.. but now i'm wondering how i would do it anyway. 16:01 <@kanzure> *on top of 16:01 <@kanzure> ok 16:01 -!- _Sketch_ [~Sketch@71-81-148-153.dhcp.stls.mo.charter.com] has quit [Read error: Connection reset by peer] 16:07 -!- _Sketch_ [~Sketch@71-81-148-153.dhcp.stls.mo.charter.com] has joined ##hplusroadmap 16:12 -!- lichen [~lichen@c-76-105-164-184.hsd1.or.comcast.net] has joined ##hplusroadmap 16:13 -!- Jora [~Jora@unaffiliated/jora] has quit [Quit: Leaving] 16:22 -!- NonFish[ [~lurking@adsl-108-79-213-97.dsl.ipltin.sbcglobal.net] has joined ##hplusroadmap 16:26 -!- NonFish_ [lurking@adsl-108-79-213-97.dsl.ipltin.sbcglobal.net] has quit [Ping timeout: 252 seconds] 16:26 -!- NonFish[ is now known as NonFish_ 16:31 -!- ThomasEgi [~thomas@pppdyn-07.stud-ko.rz-online.net] has joined ##hplusroadmap 16:31 -!- ThomasEgi [~thomas@pppdyn-07.stud-ko.rz-online.net] has quit [Changing host] 16:31 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap 16:34 -!- strages_shop [~strages@256.makerslocal.org] has quit [Ping timeout: 252 seconds] 16:36 -!- strages_shop [~strages@256.makerslocal.org] has joined ##hplusroadmap 16:40 -!- strages_shop [~strages@256.makerslocal.org] has quit [Ping timeout: 244 seconds] 16:46 -!- strages_shop [~strages@256.makerslocal.org] has joined ##hplusroadmap 17:01 -!- chris_99 [~chris@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 17:06 < delinquentme> I think the term " hit site " that I've been using is incorrect 17:07 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Remote host closed the connection] 17:07 < delinquentme> anyways I'm looking for a program that I could compare a list of chemicals to a binding site for possible candidates 17:07 <@kanzure> CHARMM. 17:07 <@kanzure> or other molecular physics simulators. 17:10 < delinquentme> so like 17:11 < delinquentme> I need to do folding type processing to get out candidates? 17:12 <@kanzure> folding is only for folding amino acids into proteins 17:14 < delinquentme> biobricks dont happen to have their yield molecules in that database do they? 17:14 < delinquentme> bc I'd need those to run the site matching 17:14 <@kanzure> what? 17:14 < delinquentme> of the "hit sites" 17:14 < delinquentme> like where the molecules would bind to one another 17:15 <@kanzure> biobricks can't do "yields" because that entirely depends on the circuit, not the component 17:15 <@kanzure> the binding sites are annotated in pdb and on some ncbi somewhere, probably entrez 17:15 <@kanzure> *on some ncbi site somewhere 17:15 < delinquentme> so it would be more what that gene codes for 17:16 -!- strages_1hop [~strages@256.makerslocal.org] has joined ##hplusroadmap 17:16 <@kanzure> what are you doing? 17:16 < delinquentme> biobricks contains genes as well 17:16 < delinquentme> I'm trying to put together a simple example of picking out a molecule from the KEGG database 17:16 < delinquentme> and then matching it with some new gene to make a novel modification 17:16 <@kanzure> do you mean a protein? 17:17 <@kanzure> ok. so you want to find proteins that bind together? 17:17 < delinquentme> yeah 17:17 <@kanzure> look up cofactors or ligand binding 17:18 < delinquentme> what they make is totally arbitrary so long as whatever protein the new gene codes for is non-naturally occuring 17:18 < delinquentme> and it reacts with / matches the selected protein yield from the normal Ecoli pathway 17:18 <@kanzure> ok then that is called "rational protein design" or "rational protein engineering" 17:19 -!- strages_shop [~strages@256.makerslocal.org] has quit [Ping timeout: 245 seconds] 17:20 < delinquentme> kk 17:20 < delinquentme> be back later 17:20 -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Quit: Leaving] 17:26 -!- strages_1hop [~strages@256.makerslocal.org] has quit [Ping timeout: 244 seconds] 17:28 -!- strages_shop [~strages@256.makerslocal.org] has joined ##hplusroadmap 18:21 < fenn> archels: http://nipo1987.web.fc2.com/RRK.html 18:32 -!- lichen [~lichen@c-76-105-164-184.hsd1.or.comcast.net] has quit [Quit: KVIrc 4.0.2 Insomnia http://www.kvirc.net/] 18:38 -!- lichen [~lichen@c-76-105-164-184.hsd1.or.comcast.net] has joined ##hplusroadmap 18:44 -!- Jora [~Jora@unaffiliated/jora] has joined ##hplusroadmap 19:29 -!- klafka1 [~klafka@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap 19:49 -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap 19:50 -!- docl [~luke@unaffiliated/docl] has quit [Quit: Lost terminal] 19:56 -!- klafka1 [~klafka@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Ping timeout: 265 seconds] 19:59 -!- klafka1 [~klafka@c-24-6-19-91.hsd1.ca.comcast.net] has joined ##hplusroadmap 20:42 -!- strages_shop [~strages@256.makerslocal.org] has quit [Ping timeout: 265 seconds] 21:04 -!- McClaw [~claudio@186.129.185.155] has joined ##hplusroadmap 21:06 -!- docl [~luke@71-32-250-171.ptld.qwest.net] has joined ##hplusroadmap 21:06 -!- docl [~luke@71-32-250-171.ptld.qwest.net] has quit [Changing host] 21:06 -!- docl [~luke@unaffiliated/docl] has joined ##hplusroadmap 21:10 -!- McClaw [~claudio@186.129.185.155] has left ##hplusroadmap ["Saliendo"] 21:10 -!- _Sketch_ [~Sketch@71-81-148-153.dhcp.stls.mo.charter.com] has quit [Read error: Connection reset by peer] 21:10 -!- _Sketch_ [~Sketch@71-81-148-153.dhcp.stls.mo.charter.com] has joined ##hplusroadmap 21:23 -!- klafka1 [~klafka@c-24-6-19-91.hsd1.ca.comcast.net] has quit [Ping timeout: 256 seconds] 21:51 -!- Jora [~Jora@unaffiliated/jora] has quit [Quit: Leaving] 22:44 -!- strages_home [~strages@adsl-98-81-21-7.hsv.bellsouth.net] has quit [Ping timeout: 256 seconds] 22:46 -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Ping timeout: 256 seconds] 23:02 -!- Tukotih [~Tukotih@81.231.85.111] has joined ##hplusroadmap --- Log closed Tue Jun 12 00:00:38 2012