--- Log opened Fri Jun 22 00:00:47 2012
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07:40 < kanzure> beeep
07:44 < ThomasEgi> *honk*
07:48 < chido> good morning, I assume
07:50 < kanzure> "S-52, a novel nootropic compound, protects against β-amyloid induced neuronal injury by attenuating mitochondrial dysfunction." http://www.ncbi.nlm.nih.gov/pubmed/22714678
07:51 < kanzure> "Accumulating evidence suggests that β-amyloid (Aβ)-induced oxidative DNA damage and mitochondrial dysfunction may initiate and contribute to the progression of Alzheimer's disease (AD). This study evaluated the neuroprotective effects of S-52, a novel nootropic compound, on Aβ-induced mitochondrial failure."
07:51 < kanzure> "In an established paradigm of moderate cellular injury induced by Aβ, S-52 was observed to attenuate the toxicity of Aβ to energy metabolism, mitochondrial membrane structure, and key enzymes in the electron transport chain and tricarboxylic acid cycle. In addition, S-52 also effectively inhibited reactive oxygen species accumulation dose dependently not only in Aβ-harmed cells but also in unharmed, normal cells"
07:51 < kanzure> "The role of S-52 as a scavenger of free radicals is involved in the antioxidative effect of this compound. The beneficial effects on mitochondria and oxidative stress extend the neuroprotective effects of S-52."
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07:55 < chido> ad mitochondrial damage: Britain is a step closer to allowing DNA swaps that, when combined with in vitro fertilization, may spare children from inherited mitochondrial diseases.
07:55 < chido> it's sort of cool, having three parents
07:55 < chido> mom, dad and whoever donates the mitochondria
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09:44 < kanzure> http://www.enewman.co.uk/the-joy-of-blogging/this-is-not-a-girl-thing
09:44 < kanzure> man, someone should be shot over that.
09:45 < kanzure> "This is a video released by the European Commission as a “teaser” to a campaign designed to attract more women to careers in science. Let me say that again: released by the European Commission. Not a beauty magazine, not a cosmetics company but a government organisation."
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09:51 < |VIPPER|> jose emmanual baroso
10:00 < Urchin> that's fucked up
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10:11 < audy> it's a commercial for a makeup brand called science?
10:11  * audy hurt himself in his confusion
10:13 < Urchin> lol
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12:58 < Jorgebio> Hi all
12:59 < yashgaroth> hello
12:59 < kanzure> hello
12:59 < Jorgebio> Hi hi
12:59 < Jorgebio> Where you from?
13:01 < kanzure> madrid, spain
13:02 < Jorgebio> kanzure, like me
13:02 < kanzure> well, no.. austin, texas.
13:02 < Jorgebio> ?
13:03 < Jorgebio> You live in texas but born in Madrid?
13:03 < kanzure> no.. i was just trying to figure out where you lived
13:04 < Jorgebio> Yes
13:04 < Jorgebio> I live in Madrid
13:04 < Jorgebio> Which topics you talk about here?
13:08 < mensch> Dirty things
13:09 < kanzure> Jorgebio: do you know starlab?
13:10 < chido> kanzure: I'd gladly do the shooting personally. I am allergic to anything that implies that making something pink will make girls flock to it
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13:10 < Jorgebio> no kanzure what is this?
13:12 < kanzure> eh just something i remembered.. i thought it was a hackerspace in madrid
13:12 < kanzure> maybe it's barcelona
13:13 < Jorgebio> Im PhD in biology and begun researching in systems biology
13:14 < kanzure> how'd you find hplusroadmap?
13:17 < Jorgebio> ah
13:17 < Jorgebio> searching with X-chat
13:19 < kanzure> alright. cool.
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15:28 < kanzure> http://techup.ch/705/vive-la-resistance-workshop-biohacking-discussion
15:28 < kanzure> "Swiss Mechatronic Art Society (SGMK) and hackteria invite you to a "Vive la Resistance" make-away and a biohacking discussion. In this expanded workshop we will build a simple circuit that has an oscillator and a resistive gas sensor self-made out of soot aka saje (carbon nanoparticles)."
15:28 < kanzure> "The output can be both a blinking LED and also a speaker that produces sounds. Breath on it, drink some alcohol and breath on it again, and listen to the resistance sing."
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17:52 < kanzure> http://www.kickstarter.com/projects/763704741/synthboy
17:52 < kanzure> gameboy synthesizer docking station?
17:54 < ThomasEgi> oh VERY YES!! do want!
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17:55 < ThomasEgi> friend of mine went as far as resoldering and reflashing the eeproms of old games to get a synthesizer running ond his gameboy
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19:13 < kanzure> some afm videos:
19:13 < kanzure> http://ocw.mit.edu/courses/biological-engineering/20-309-biological-engineering-ii-instrumentation-and-measurement-fall-2006/tools/
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19:14 < kanzure> some ok microfabrication notes:
19:14 < kanzure> http://ocw.mit.edu/courses/electrical-engineering-and-computer-science/6-152j-micro-nano-processing-technology-fall-2005/lecture-notes/
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22:00 < kanzure> http://www.nature.com/news/scientists-trace-a-wiring-plan-for-entire-mouse-brain-1.10878
22:00 < kanzure> "Cold Spring Harbor Laboratory (CSHL) in Long Island, N.Y., have started making public detailed images of mouse brain circuitry, releasing on June 1 the first installment of about 500 terabytes. The goal of the effort, called the Mouse Brain Architecture Project (MBA), is an entire rodent brain wiring plan that would represent the first such mapping of the circuits of a vertebrate brain."
22:00 < kanzure> http://mouse.brainarchitecture.org/
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22:36 < ParahSailin__> what is the deal with functional programming like haskell, clojure
23:00 < kanzure> http://www.enmcu.com/projects/electromyogramemgamplifier
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23:01 < kanzure> enuresis alarm http://cappels.org/dproj/bwalrm/bedwet.html
23:01 < kanzure> low-cost hearing aid http://www.electronicsforu.com/efylinux/circuit/aug2003/ci-2-hearing-aid.pdf
23:01 < kanzure> footstep detector http://www.discovercircuits.com/DJ-Circuits/geophonealarm1.htm
23:02 < kanzure> ultrasonic transmitter/receiver http://www.4qdtec.com/ultra.html
23:26 < brownies> it takes 500TB to store a mouse brain?
23:26 < brownies> or is it the schematics for a mouse eigen-brain?
23:26  * brownies reads
23:26 < kanzure> it's probably 1 pixel/nm
23:26 < kanzure> or something
23:27 < brownies> looks like i still can't program a mouse to be my personal chef
23:36 < kanzure> you can stare at them funny until they twitch
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--- Log closed Sat Jun 23 00:00:48 2012