--- Log opened Tue Jul 17 00:00:11 2012 00:16 -!- Mokbortolan_ [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has joined ##hplusroadmap 00:18 -!- Mokbortolan_1 [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has quit [Ping timeout: 246 seconds] 00:18 -!- joshcryer [g@unaffiliated/joshcryer] has joined ##hplusroadmap 00:20 * Mokbortolan_ breaks out the liquid electrical tape. 00:21 * Mokbortolan_ stacks four 3v coin cells to make a 12v stack. 00:22 < Mokbortolan_> would anybody mind teaching me how to read my multimeter? 00:23 < Mokbortolan_> it's the analog kind 00:23 < Mokbortolan_> are the numbers on the dial multipliers? 00:26 < Mokbortolan_> n/m, figured it out 00:43 -!- klafka1 [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has quit [Ping timeout: 255 seconds] 00:51 -!- Mokbortolan_ [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has quit [Ping timeout: 246 seconds] 00:52 -!- Moktart [~Mokalypso@c-76-115-136-13.hsd1.or.comcast.net] has quit [Ping timeout: 246 seconds] 00:53 -!- Moktart [~Mokalypso@c-76-115-136-13.hsd1.or.comcast.net] has joined ##hplusroadmap 00:57 -!- Mokbortolan_ [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has joined ##hplusroadmap 01:12 -!- superkuh_ [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap 01:12 -!- superkuh_ [~superkuh@unaffiliated/superkuh] has quit [Read error: Connection reset by peer] 01:13 -!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap 01:40 -!- AdrianG_ [~ircname@unaffiliated/amphetamine] has joined ##hplusroadmap 01:40 -!- AdrianG_ is now known as AdrianG 02:04 -!- AdrianG [~ircname@unaffiliated/amphetamine] has quit [Ping timeout: 248 seconds] 02:19 -!- AdrianG_ [~ircname@unaffiliated/amphetamine] has joined ##hplusroadmap 02:35 -!- klafka [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap 03:00 -!- sylph_mako [~mako@22.67.252.27.dyn.cust.vf.net.nz] has quit [Ping timeout: 248 seconds] 03:13 -!- brownies [u1042@gateway/web/irccloud.com/x-yvwhncambhivnmjt] has quit [Remote host closed the connection] 03:13 -!- Lemminkainen [u2346@gateway/web/irccloud.com/x-ilsmrofveimodtmc] has quit [Remote host closed the connection] 03:14 -!- upgrayeddd [u2969@gateway/web/irccloud.com/x-hycessezbjaagqql] has quit [Remote host closed the connection] 03:19 -!- brownies [u1042@gateway/web/irccloud.com/x-vdxtnldzsiamhpvm] has joined ##hplusroadmap 03:22 -!- AdrianG_ [~ircname@unaffiliated/amphetamine] has quit [] 03:41 < Utopiah> https://www.coursera.org/course/drugsandbrain 04:13 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 04:37 -!- klafka [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has quit [Ping timeout: 246 seconds] 04:37 -!- klafka [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap 05:07 -!- joshcryer [g@unaffiliated/joshcryer] has quit [] 05:09 < rdb> Utopiah, cool, thanks for link 05:09 < Utopiah> np 05:36 -!- chevbird [~chevbird@66-87-83-250.pools.spcsdns.net] has quit [Quit: AndroIRC - Android IRC Client ( http://www.androirc.com )] 07:51 -!- Thorbinator1 [~Thorbinat@c-67-166-146-169.hsd1.ca.comcast.net] has quit [Quit: Leaving.] 07:52 -!- Thorbinator [~Thorbinat@c-67-166-146-169.hsd1.ca.comcast.net] has joined ##hplusroadmap 07:56 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 244 seconds] 08:01 -!- Mokbortolan_ [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has quit [Read error: Connection reset by peer] 08:11 < kanzure> http://www.danielwillingham.com/1/post/2012/05/the-latest-on-intelligence.html 08:11 < kanzure> heh what? "Almost no genetic polymorphisms have been discovered that are consistently associated with variation of IQ in the normal range." 08:11 < kanzure> http://scottbarrykaufman.com/wp-content/uploads/2012/01/Nisbett-et-al.-2012.pdf 08:18 < kanzure> ParahSailin__: did you look at the ben wpan thing from qi hardware? 08:36 -!- Guest_ [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap 08:37 -!- shin-to [~shin-to@ulmg-4d0227d7.pool.mediaWays.net] has joined ##hplusroadmap 08:38 -!- nsh [~nsh@109.144.203.160] has joined ##hplusroadmap 08:38 -!- nsh [~nsh@109.144.203.160] has quit [Changing host] 08:38 -!- nsh [~nsh@wikipedia/nsh] has joined ##hplusroadmap 08:41 -!- Thorbinator [~Thorbinat@c-67-166-146-169.hsd1.ca.comcast.net] has quit [Quit: Leaving.] 08:42 -!- Thorbinator [~Thorbinat@c-67-166-146-169.hsd1.ca.comcast.net] has joined ##hplusroadmap 08:51 -!- Mokbortolan_ [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has joined ##hplusroadmap 09:06 -!- Guest_ [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has quit [Quit: Textual IRC Client: http://www.textualapp.com/] 09:18 -!- shin-to_ [~shin-to@ulmg-5d84d6f2.pool.mediaWays.net] has joined ##hplusroadmap 09:19 -!- shin-to [~shin-to@ulmg-4d0227d7.pool.mediaWays.net] has quit [Ping timeout: 246 seconds] 09:19 -!- shin-to_ is now known as shin-to 09:23 -!- nsh [~nsh@wikipedia/nsh] has quit [Ping timeout: 255 seconds] 09:29 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 09:37 -!- superkuh [~superkuh@unaffiliated/superkuh] has quit [Quit: arma 2] 09:39 -!- Netsplit *.net <-> *.split quits: Guest44728, splicer, chris_99, archels, Urchin, lichen 09:50 -!- Netsplit over, joins: chris_99 09:57 -!- lichen [~lichen@c-24-21-206-64.hsd1.or.comcast.net] has joined ##hplusroadmap 09:57 -!- archels [~foo@sascha.esrac.ele.tue.nl] has joined ##hplusroadmap 09:57 -!- splicer [~ubuntu@c83-255-190-140.bredband.comhem.se] has joined ##hplusroadmap 09:57 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 09:57 -!- Guest44728 [~quassel@64.31.59.70] has joined ##hplusroadmap 10:08 -!- upgrayeddd [u2969@gateway/web/irccloud.com/x-kjotqzxjcppplkyg] has joined ##hplusroadmap 10:08 < kanzure> http://www.nature.com/scitable/blog/theprometheancell/diybio_first_impressions 10:08 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Read error: Operation timed out] 10:21 -!- Cat4D [182bc9d2@gateway/web/freenode/ip.24.43.201.210] has joined ##hplusroadmap 10:25 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 10:54 -!- shin-to_ [~shin-to@ulmg-5d84da4f.pool.mediaWays.net] has joined ##hplusroadmap 10:56 -!- shin-to [~shin-to@ulmg-5d84d6f2.pool.mediaWays.net] has quit [Ping timeout: 265 seconds] 10:56 -!- shin-to_ is now known as shin-to 11:03 -!- AdrianG_ [~ircname@unaffiliated/amphetamine] has joined ##hplusroadmap 11:03 < AdrianG_> hy guiz 11:03 -!- AdrianG_ is now known as AdrianG 11:05 < kanzure> for x in `find . \( -name url.txt -o -name urls.txt \) -print`; do cat "$x"; done | grep http | wc -l 11:05 < kanzure> 10132 11:06 < kanzure> this is how i keep track of where i download all the things. 11:11 -!- sylph_mako [~mako@22.67.252.27.dyn.cust.vf.net.nz] has joined ##hplusroadmap 11:14 < AdrianG> kanzure when do you sleep 11:14 < AdrianG> are you ever offline 11:15 < kanzure> well, i'm certainly never offline, but that is independent of my sleep 11:15 < kanzure> i usually sleep between 1am and 6am 11:16 < AdrianG> 5 hrs? 11:16 < kanzure> it varies 11:17 < Sanky|test> do you wake naturally or do you use alarms? 11:17 -!- Sanky|test is now known as Sanqui 11:17 -!- Lemminkainen_ [u2346@gateway/web/irccloud.com/x-jenxbrgidyfzcvzl] has joined ##hplusroadmap 11:18 < kanzure> that also varies, i wake naturally at 7 hours but i do tend to set alarms for <7 hours 11:18 < Sanqui> I see. 11:19 < kanzure> why are my sleeping habits of sudden interest? 11:19 < Sanqui> I jumped at it since it was mentioned. 11:19 < kanzure> if you are planning to rob me please rob me between the hours of 4pm and 6pm M-F and 3pm on Saturdays (Sundays aren't OK) 11:20 < Sanqui> I'll try to keep it in mind 11:21 < Lemminkainen_> Sanqui: gonna steal kanzure 's potato 11:26 -!- nmz787 [~Nathan@173-163-203-241-Richmond.hfc.comcastbusiness.net] has joined ##hplusroadmap 11:31 < nmz787> has anyone here actually read that Biopunk book? 11:32 < kanzure> http://diyhpl.us/~bryan/papers2/diybio/biopunk.pdf 11:32 < kanzure> i've flipped through it, but no. my grandma has, does that count? 11:33 < nmz787> have you conversed with her about it? 11:33 < kanzure> hmm, why do you ask? 11:34 < nmz787> read that nature post you mentioned earlier 11:34 < kanzure> did marcus email you when he was writing the book? 11:34 < nmz787> nope 11:34 < kanzure> he sent out emails to pretty much everyone in the book 11:34 < kanzure> asking for permission to include certain things, or to look over certain passages, things like that.. 11:35 < nmz787> hmm 11:35 < nmz787> I don't know why Meredith Patterson is mentioned and quoted so much, seems like openPCR accomplished more than she did 11:36 < nmz787> at one point as I remember she was using the wrong kind of promoters or something, which is an easy google scholar search away 11:36 < kanzure> openpcr was after the book was published 11:37 < kanzure> meredith got a lot of press attention because she was the only alternative to "DIYbio" which had some issues with too-much-connections-to-igem or something 11:38 < kanzure> the other reason is because marcus was the one who originally did the story on meredith on AP 11:39 < kanzure> which sorta started the media spiral death trap 11:39 < nmz787> alternative to DIYbio? 11:39 < nmz787> oh 11:39 < kanzure> well i mean, alternative person to focus on 11:39 -!- nsh [~nsh@wikipedia/nsh] has joined ##hplusroadmap 11:39 < kanzure> remember, mac used to be running some part of igem (i forget which part), and jason was always a part of some harvard lab 11:39 < kanzure> so by those standards, meredith was significantly more amateur :P 11:41 < nmz787> sure 11:42 * nsh wonders about superkuh's quitline 11:42 < kanzure> nmz787: http://openwetware.org/wiki/DIYbio/FAQ/News 11:43 < kanzure> nmz787: he was fascinated by models of neuron firing for a while 11:44 < kanzure> oops, i meant nsh 11:44 < nsh> ah, thanks 11:44 < nsh> is that an accepted statement of fact then? or conjectural? 11:44 < kanzure> http://superkuh.com/library/Neuroscience/Lipid%20Membrane/ 11:45 < kanzure> he lost his files recently in an fbi raid, so it seems that some of the propagating-density-stuff is presently missing 11:45 < nsh> "This FAQ for DIYbio is actively maintained by it's editors" no apostrophe required 11:45 < nsh> heh, fbi raid? 11:45 < kanzure> nsh: http://superkuh.com/library/Neuroscience/Lipid%20Membrane/Rapid%20mechanical%20and%20thermal%20changes%20in%20the%20garfish%20olfactory%20nerve%20associated%20with%20propagated%20impulse_%20Tasaki%20I_%20Kusano%20K_%20Byrne%20PM_%201989.pdf 11:46 < kanzure> nsh: i didn't write that line (that was jonathan cline) 11:46 < kanzure> and it's not actually 'actively' maintained :P i don't think he's edited it in a year. 11:46 * nsh nods - just wasn't sure i could be bothered to create a login to edit it 11:46 < nsh> okay 11:46 < kanzure> http://superkuh.com/library/Neuroscience/Lipid%20Membrane/Phase%20transition%20in%20membrane%20with%20reference%20to%20nerve%20excitation_%20Kobatake%20Y_%20Tasaki%20I_%20Watanabe%20A_%20advbiophys_1971.pdf 11:46 < nsh> thanks and thanks 11:46 < kanzure> oh, yeah, creating logins on openwetware is painful and stupid 11:47 < kanzure> http://superkuh.com/library/Neuroscience/Lipid%20Membrane/Volume%20expansion%20of%20nonmyelinated%20nerve%20fibers%20during%20impulse%20conduction_%20Tasaki%20I_%20Byrne%20PM_%201990.pdf 11:47 < kanzure> well, anyway, i expect he would be better at picking out a good article 11:48 * nsh nods 11:48 < AdrianG> ok 11:48 < AdrianG> what are the most potent nootropics 11:49 < kanzure> well, there are many drugs that modulate the brain 11:49 < kanzure> some just make people feel good, which isn't a bad thing 11:50 < kanzure> if you want an unpopular answer to your question, i would say that a minimum nootropic is one that has some measurable result like, making you better at making a better nootropic, which almost none do 11:50 < nsh> tell that to shulgin 11:50 < nmz787> nsh: what is that quitline you're talking about? 11:50 < nmz787> kanzure: fbi raid? 11:50 < kanzure> that's just shulgin being shulgin 11:50 < nsh> superkuh has quit (Quit: the neuronal action potential is an electrical manipulation of reversible abrupt phase changes in the lipid bilayer) 11:51 < kanzure> nmz787: he doesn't want to talk about the raid 11:51 < nsh> understandably 11:51 < nmz787> nsh: It'd be cool to meet Shulgin, but I think he's too old these days to entertain many folks 11:51 < kanzure> too old? that's the best kind of old 11:51 < AdrianG> kanzure: if it makes me feel good its good enough for me 11:51 < kanzure> AdrianG: then why not just use heroin 11:51 < AdrianG> unsustainable 11:51 < AdrianG> plus a messy administration path 11:52 < kanzure> ok. so it sounds like you don't actually want nootropics though? 11:52 < nsh> AdrianG, http://en.wikipedia.org/wiki/25I-NBOMe 11:52 < nmz787> nsh: i thought you meant like a toll-free phone number, e.g. smoking quitline 11:52 < AdrianG> nah nootropics are good 11:52 < AdrianG> nsh: what is it 11:52 < AdrianG> a psychedelic? 11:52 < nsh> yes 11:52 < kanzure> like, what if the drug made you into a super-working transhumanist, but made you fucking miserable? 11:52 < nsh> like university? 11:52 < AdrianG> nsh: and whats so good about it 11:52 < AdrianG> kanzure: you mean like meth? 11:53 < kanzure> i haven't met any transhumanists on meth, or any productive transhumanists on meth 11:53 * nsh chuckles 11:53 < kanzure> so no, not like meth 11:53 < AdrianG> im pretty sure desoxyn is very popular in the Silicon Valley. 11:53 < AdrianG> ive heard its the most common adhd drug in that area. 11:53 < nmz787> nsh: looks like most of the items in PIHKAL 11:54 < nsh> AdrianG, http://www.erowid.org/experiences/subs/exp_2CINBOMe.shtml 11:54 < nmz787> desoxyn == meth 11:54 < nmz787> in tablet 11:54 < nmz787> :D 11:54 < AdrianG> methamphetamine is methamphetamine 11:54 < AdrianG> nsh: i dont see anything nootropical about this 11:54 < kanzure> i don't see what SV has to do with it 11:54 < nsh> it has some potential, though i suspect the main obstacles in psychedelic-based phenomenological research are intersubjective, rather than stereochemical 11:54 -!- shin-to [~shin-to@ulmg-5d84da4f.pool.mediaWays.net] has quit [Ping timeout: 246 seconds] 11:54 < AdrianG> plus i cannot take psychedelics 11:54 < AdrianG> i have increased risks of HPPD 11:54 < kanzure> i also don't see why it has to be a euphoric drug 11:55 < AdrianG> because hyperthymia is conducive to being productive 11:55 < nsh> creativity and euphoria are correlated 11:55 < AdrianG> and difference between euphoria and hyperthymia is just that of a degree 11:55 < nmz787> http://www.erowid.org/experiences/exp.php?ID=95977 11:55 < nmz787> one of two refs to transhumanist in the experiences 11:55 < kanzure> yes but said "euphoria" hasn't been enough to make any of the meth-heads make better nootropics (which was my original test i offered) 11:55 < AdrianG> meth is a productivity drug. 11:55 < nmz787> ibogaine is active in addiction treament centers in mexico 11:55 < nsh> kanzure, ok 11:56 < kanzure> AdrianG: i am arguing that the production output is not interesting. cleaning? shit, hire someone for <$50/hour to do that. 11:56 < AdrianG> kanzure: it'll increase productivity of anything you are doing 11:56 < AdrianG> increased energy/focus/concentration cant hurt. 11:57 < kanzure> i don't seem to be communicating with you 11:57 < kanzure> what do you think i am saying? 11:57 < AdrianG> production output is not interesting. 11:57 * nsh is dubious 11:57 < AdrianG> that's a strange thing to say. everything you do is an output. 11:57 < kanzure> i was saying, specifically, the production output of meth-heads 11:57 < AdrianG> we are not talking about addicts 11:57 < nsh> efficacy in one domain is generally at the expense of another 11:57 < kanzure> i have never heard of a meth-head making a better drug 11:58 < AdrianG> nsh: stimulants are overdrive drugs 11:58 < kanzure> and i have never heard of a heroin experience leading to a better drug 11:58 < AdrianG> you pay for it later. 11:58 < AdrianG> kanzure: let me guess, LSD led to something else? 11:58 < kanzure> what? 11:58 < nmz787> in shulgins cas 11:58 < nmz787> e 11:58 < AdrianG> what other drugs lead to better drugs? 11:58 < nmz787> I generally revere psychedelics 11:58 < nmz787> but they aren't for everyyday 11:58 < kanzure> AdrianG: my point is that so far there hasn't been anything that reliably leads to better systematic search of nootropics 11:59 < AdrianG> you can take them daily anywya, its impossible 11:59 < nsh> AdrianG, have you tried playing buckaroo after 12 cups of coffee? 11:59 < AdrianG> kanzure: that has no bearing on their effectivness 11:59 < nmz787> sure you can 11:59 < AdrianG> you expect a breakthrough in a pill 11:59 < kanzure> a LSD trip might lead to some strange concept by accidet, but that's not a nootropic effect 11:59 < kanzure> that's a psychedelic effect 11:59 < AdrianG> nsh: ofc not, i dont drink coffee 11:59 < nmz787> the dose doesn't have to be tripping-level 11:59 < AdrianG> nmz787: tolerance 12:00 < nmz787> sub-active doses improve things in a less perceptible manner, such that you aren't going crazy with colors and can't talk to people 12:00 < AdrianG> tryptamine/phenethylamines build up tolerance really quick 12:00 < kanzure> i strongly disagree with the premise that tripping and randomly disrupting the brain is the only way to design new drugs 12:00 < nmz787> so dose heroin and meth 12:00 < nmz787> does* 12:00 < AdrianG> nmz787: amphetamines maintain their concentrating/focusing effect 12:00 < nmz787> kanzure: I'm not advocating that 12:00 < nsh> kanzure, you can find bugs by analysis of source code, you can also find bugs by fuzzing 12:00 < kanzure> nmz787: AdrianG is. 12:00 < rdb> AdrianG, they also build off tolerance really quick 12:00 < AdrianG> euphoria/mood boost will go away 12:00 < nsh> if people are willing to do that to themselves, i won't try to talk them out of it 12:00 < AdrianG> rdb: concentration stays, only mood elevation goes away 12:01 < kanzure> nsh: there are millions of people "fuzzing" their brain, and the results aren't that interesting to me so far 12:01 < kanzure> nsh: so, that argument doesn't make sense to me. 12:01 * nsh shrugs 12:01 < rdb> AdrianG, I mean tryptamines and serotoninergic psychedelics build off tolerance quickly 12:01 < kanzure> nsh: specifically we are talking about nootropics 12:01 < AdrianG> rdb: yes i am well aware thx cpt obvious 12:01 < nsh> right 12:01 < nmz787> AdrianG: I took amphetamines prescribed for many years and the concetration isn't maintained 12:01 < AdrianG> nmz787: adhd? 12:01 < kanzure> nsh: randomly fuzzing your brain and breaking things has various benefits for personal development blah blah blah, but that's not the conversation 12:01 < nsh> kanzure, sure 12:02 < nmz787> there's no rule book that says you need to take nootropics daily 12:02 < AdrianG> ITS LAW 12:02 < nmz787> you can definitely sustain a weekly trip 12:02 < AdrianG> lol a weekly trip 12:03 < nmz787> I think psychedelics are more about paradigm transcending or shifting 12:03 < AdrianG> they just demolish your ego 12:03 < AdrianG> so that you are not constrained by your monkey/reptile brain 12:03 < nmz787> not in all dose levels though 12:03 < AdrianG> its a matter of degree 12:03 < AdrianG> ego death vs ego weakening 12:03 < rdb> not really 12:03 -!- pasky [pasky@nikam.ms.mff.cuni.cz] has quit [Ping timeout: 245 seconds] 12:03 < kanzure> man, everyone talks about that 12:04 < AdrianG> what else is useful about psychedelics? 12:04 < kanzure> and they all think they are being insightful because they have had trips 12:04 < AdrianG> except unchaining you? 12:04 < nmz787> like I said, in sub-active doses they merely do things to subconscious rather than modify your whole personality... i.e. make patterns more recognizable 12:04 < AdrianG> nmz787: so ok your brains are loosened up slightly 12:04 < nmz787> a good book is http://www.amazon.com/Food-Gods-Original-Knowledge-Evolution/dp/0553371304 12:04 < rdb> in low doses psychedelics are very productive with barely any of the distracting effects 12:04 < AdrianG> whats the difference between a total unravelling 12:04 < AdrianG> and a slight loosening up? 12:05 < nmz787> AdrianG: worlds of difference 12:05 < rdb> how much experience do you have with psychedelics and different dosages? 12:05 < AdrianG> i dont like psychedelics 12:05 < kanzure> nsh: well so much for the noots conversation. 12:05 < nmz787> laying on the floor slobbering and making random noises vs in your business office and interacting with society 12:05 < AdrianG> yes it quickly degenerated 12:05 < AdrianG> nmz787: how quickly your amps lost the focus effect 12:06 < rdb> AdrianG, how often have you used psychedelics? 12:06 < AdrianG> rdb: i plead the 5th 12:06 < kanzure> nsh: maybe i am impossible to understand 12:06 < nmz787> they lost their efficacy after I started high school 12:07 -!- pasky [pasky@nikam.ms.mff.cuni.cz] has joined ##hplusroadmap 12:07 < AdrianG> nmz787: since grade 1 until high school? 12:07 < nsh> kanzure, sorry, i'm distracted 12:07 < nmz787> so time-wise it was years, but I agree that it detracted from the rest of my brains development in social/out-of-box thinking 12:07 < nmz787> grade 4 - 9 12:07 < nmz787> but i didn't need them 12:07 < nmz787> i was misdiagnosed 12:07 < nmz787> and hated them 12:08 < nmz787> i hated the high 12:08 < AdrianG> how were u misdiagnosed 12:09 < nmz787> Nootropics ( /noʊ.əˈtrɒpɨks/ noh-ə-trop-iks), also referred to as smart drugs, memory enhancers, neuro enhancers, cognitive enhancers, and intelligence enhancers, are drugs,supplements, nutraceuticals, and functional foods that improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.[1][2] The word nootropic was coined in 1972[3][4] by the  12:09 < nmz787> from wikipedia 12:09 < kanzure> i think the biggest problem is that all of those things are hard to measure 12:09 < kanzure> so some people conflate concentration with euphoria 12:10 < nmz787> for instance methadone helps my motivation way more than amphetamine 12:10 < kanzure> there are psychometric tests for each of those topics 12:10 < nmz787> which is weird, and I haven't used it in years... but amphetamine stopped motivating me when I finally said fuck this drug, because while on it I couldn't be social 12:10 < AdrianG> yeah 12:10 < kanzure> but i'm not 100% convined that the existing psychometric tests measure anything meaningful in the brain 12:11 < AdrianG> its not like amphetamines increase performance in any tests 12:11 < AdrianG> like CPT II, trails AB, etc 12:11 < kanzure> i think it would be more useful if we knew one exact microcircuit that we know can have two types of performance (terrible, and obviously better), and then develop a psychometric test for that 12:11 < AdrianG> supraphysiological doses of thyroxine are probably also nootropic to some extent 12:11 < kanzure> "stroop test" verges on almost pathetic to me :( 12:12 < AdrianG> design something better 12:12 < kanzure> that's what we're talking about, i thought 12:12 < AdrianG> increasing intelligence is hard 12:13 < AdrianG> it'd help to know what makes us intelligent in the first place 12:13 < rdb> intelligence is kind of an abstract concept in itself 12:13 < kanzure> "intelligence" is a load of poop 12:13 < rdb> an umbrella term for an array of cognitive abilities 12:13 < nmz787> i think biology may be too complex and we don't know enough to pinpoint answers today 12:14 < kanzure> nmz787: "too complex" is hand waving 12:14 < nmz787> random dosing works for some, and makes lazy bums in others 12:14 < kanzure> "intelligence" and "consciousness" is also handwaving 12:14 < nmz787> monte carlo is a bitch, but its evolution i guess 12:14 < kanzure> it's not intelligence, it's improved performance of your hippocampal-thalamocortical tract 12:14 < kanzure> (well, no) 12:15 < kanzure> (also, that white matter tract doesn't exist) 12:15 < kanzure> but none of you called me out on that :( 12:16 -!- Cat4D [182bc9d2@gateway/web/freenode/ip.24.43.201.210] has quit [Ping timeout: 245 seconds] 12:17 * nsh delves back momentarily 12:17 * nmz787 doesn't know about them cellulars 12:17 < AdrianG> is hyperthymia a nootropic 12:18 < kanzure> AdrianG: i don't think any of the tests you proposed are nootropically-relevant, but maybe i've missed something you can point to? 12:18 * nsh blinks 12:18 < AdrianG> kanzure: how arent they nootropically relevant 12:18 < AdrianG> they attempt to measure executive function. 12:19 < kanzure> because "executive function" was defined by psychologists who didn't know about the brain 12:19 < kanzure> i want something based on neuroscience 12:21 < AdrianG> thats an arbitrary whim. 12:22 < nmz787> so if no good metric exists, I fall back to that we're left to chance 12:22 < AdrianG> so if u do insist on neuroscience 12:22 < kanzure> nmz787: or you make up metrics 12:22 < nsh> there's a law for that 12:22 < AdrianG> look into frontal dementia and executive function tests 12:22 < AdrianG> i doubt anyone will argue frontal lobes are kind of important 12:23 < kanzure> ok sure, if you remove parts of the brain things will happen 12:23 < kanzure> but that's not useful to a nootropic designer 12:23 < kanzure> if you deactive parts of the brain through remote stimulation, that might be somewhat helpful, although that's not a drug and outside the current discussion 12:23 < AdrianG> is ability to direct and deploy the focal point of your attention important to nootropic designers? 12:23 < kanzure> "attention" means what though? 12:24 * AdrianG sighs 12:24 < kanzure> please tell me which particular brain system you're talking about hacking, and don't resort to folk psychology 12:25 < AdrianG> the brain is not a lego set. 12:25 < kanzure> nobody says it was 12:25 < AdrianG> and plasma ligands are not a precise enough method 12:25 < AdrianG> to tweak specific systems 12:26 < kanzure> there are many ways to target regions, worst case scenario you get intersecting magnetic fields in the location that you want, where the accumulative field strength blah blah blah 12:27 -!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap 12:28 < AdrianG> TMG is garbage. 12:28 < kanzure> g? 12:28 < AdrianG> kanzure: u should talk to salamandyr about 12:29 < kanzure> what is psychophysics, again? 12:29 < kanzure> oh, sensor research 12:29 < AdrianG> sry TMS 12:29 < AdrianG> type. 12:29 < AdrianG> typo* 12:29 < kanzure> magnetic stimulation isn't the best example i could have used, that's true 12:31 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 248 seconds] 12:32 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 12:33 < nmz787> I think life productivity is relative 12:33 < AdrianG> no shit 12:34 < kanzure> i think the "design a better nootropic" test is somewhat relevant 12:34 < nmz787> some people love making art, and its way productive to them... others love making nanostructures, and making a fuckton of chips is productive to them 12:34 < AdrianG> yeah, good luck integrating a super-computer into your brain 12:34 < kanzure> besides, what's the point of the transhumanist takeoff if it isn't a takeoff 12:34 < nmz787> either of the two could say the other is missing out on life 12:34 < kanzure> AdrianG: supercomputers-in-a-human-skull aren't step one or necessarily anywhere in your future 12:34 < AdrianG> nmz787: thats the stupidest thing ive heard today 12:35 < AdrianG> obv productivity would be measured on a standard test 12:35 < AdrianG> i.e. your performance. 12:35 < nmz787> AdrianG: A lot of people think I say stupid things, but its relavant to me 12:35 < kanzure> nmz787: it's not whether or not other people think you are happy 12:35 < AdrianG> anything that boosts cerebral metabolism is going to be nootropical 12:35 < AdrianG> or enhances energy utilization 12:35 -!- nsh [~nsh@wikipedia/nsh] has quit [Ping timeout: 250 seconds] 12:35 < kanzure> AdrianG: not true; just because you consume energy doesn't mean you're doing anything 12:35 < AdrianG> kanzure: the brain has a limited supply of glucose. 12:35 < AdrianG> understand? limited. 12:35 < kanzure> nmz787: "making art" is cool and all, but can you scale that up a million times? a billion times? 12:35 < nmz787> right but Richard Feynamn sucked at drawing compared to Jirary Zorthian, and ZOrthian sucked at physics/science (like, totally, he always changed the subject) 12:36 < nmz787> but they were both great in their own fields 12:36 * nmz787 lived at the Zorthian ranch years ago 12:36 < AdrianG> lol wow nmz 12:36 < kanzure> nmz787: most artists seem content to limitations on their artistic creation, so i don't think that's a relevant argument against performance enhancement 12:36 < nmz787> kanzure: I imagine there are millions or billions of artists living now 12:37 < kanzure> AdrianG: if you look at the studies you will see a decrease in metabolism for increased performance (at least in some scenarios) 12:37 < AdrianG> wat 12:37 < kanzure> nmz787: i don't think you should be concerned with what other people think about you 12:38 < kanzure> nmz787: if you're not interested in personal technological enhancement, it's not a crime 12:38 < nmz787> kanzure: yeah I'm not really, but I'm trying to get my point across and it seems that AdrianG doesn't see eye to eye 12:38 < kanzure> well, i should say s/enhancement/ability-to-create-more-technology 12:38 < nmz787> kanzure: i'm interested in personal tech enhancment 12:38 < nmz787> ! 12:39 < nmz787> kanzure: that's why I want a DNA synthesizer! to create enzymes to make drugs! 12:39 < nmz787> to test on some prototype organism to see if they work 12:39 < nmz787> rather than myself 12:39 < AdrianG> you could implant a meth enzyme in yo brainz :o 12:40 < nmz787> because as I said, testing on yourself can lead to addiction/toxic problems 12:40 < kanzure> nmz787: i was making comments related to your "live and let live" "performance measurement" comment, sorry if that wasn't clear. 12:41 < nmz787> kanzure: well retrospect is what I was getting at there 12:42 < nmz787> kanzure: i.e. if we don't have a good metric /now/, we can only look at a dead person's life history to see if they were productive 12:42 < kanzure> huh? 12:43 < nmz787> well Shulgin says he started with mescaline... whether that got him interested as a chemist to pursue making more psychedelics I'm not sure 12:43 < kanzure> i don't want to argue for some universal entropic work measurement 12:43 < nmz787> so what metric could we have used on the day before he took mescaline to see if mescaline would have benefitted him positively or negatively 12:44 < nmz787> if he wouldn't have taken that, would he have never delved into making more psychedlics, or would he made even better more kickass nootropic-like chems 12:44 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 252 seconds] 12:44 < nmz787> entropic? 12:45 < kanzure> yes, entropy is one way of measuring work production 12:45 < kanzure> i specifically don't want to argue for some universal work metric 12:45 < nmz787> i was mentioning him because of your "design a better nootropic" test 12:46 < nmz787> I would argue he did "design a better nootropic", in fact two books full of them 12:46 < nmz787> or at least some of them are good 12:46 < kanzure> he seems to be the type of person that would have done that anyway, and not because of any particular drug 12:46 < kanzure> there are many people who write many volumes of books about drugs they have synthesized 12:47 < nmz787> he's the only one I know of 12:48 < kanzure> what about whitesides, karplus, corey, heeger, gratzel, huber, langer, schleyer, wutrich, bax, bard, lehn, schreiber, ... 12:48 < nmz787> but you saying he seems to be the type of person to do that anyway doesn't help us ge to a metric 12:48 < kanzure> these are all individuals who have written mountains of literature about synthesis (some percent of which they have synthesized) 12:48 < nmz787> whitesides made drugs? 12:48 < kanzure> no, i'm just talking about people who write lots of books about chemicals 12:48 < nmz787> i don't recognize the other names 12:48 < kanzure> independent of drug ingestion 12:49 < kanzure> i'm saying that writing volumes of books about chemicals is not a trait bestowed by some nootropic effect 12:49 -!- sylph_mako [~mako@22.67.252.27.dyn.cust.vf.net.nz] has quit [Ping timeout: 248 seconds] 12:50 < nmz787> right, but I'm saying shulgin did attempt and may have succeeded to "design a better nootropic" 12:50 < nmz787> that was practically his mission statement 12:50 < kanzure> i just remember it getting him high 12:50 < kanzure> i haven't read his books in a long time 12:50 < kanzure> a very long time 12:58 -!- Netsplit *.net <-> *.split quits: ParahSailin__, klafka 13:02 -!- Netsplit over, joins: ParahSailin__ 13:02 -!- Steel2 [ad42e490@gateway/web/freenode/ip.173.66.228.144] has quit [Ping timeout: 245 seconds] 13:04 -!- klafka [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap 13:07 -!- shin-to [~shin-to@ulmg-5d84dc3c.pool.mediaWays.net] has joined ##hplusroadmap 13:24 -!- Mokbortolan_1 [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has joined ##hplusroadmap 13:25 -!- Mokbortolan_ [~Nate@c-76-115-136-13.hsd1.or.comcast.net] has quit [Ping timeout: 248 seconds] 13:37 -!- yorick [~yorick@unaffiliated/yorick] has joined ##hplusroadmap 13:38 < kanzure> damn, someone should do cclive/youtube-dl for mediafire and all those other terrible sites 13:38 < kanzure> i guess that has to be me 13:42 -!- Moktart [~Mokalypso@c-76-115-136-13.hsd1.or.comcast.net] has quit [Read error: Connection timed out] 13:43 -!- Moktart [~Mokalypso@c-76-115-136-13.hsd1.or.comcast.net] has joined ##hplusroadmap 13:56 < kanzure> huh, mediafire takes surprisingly little precautions from multiple ip addresses using the same exact authentication tokens 13:56 < kanzure> so what's the point of these "wait to download the file" things if i can just bypass that completely by distributing wget scripts 13:57 < nmz787> how long is the token good for though 13:58 < kanzure> nmz787: let's try it.. one sec 14:00 < kanzure> nmz787: curl http://diyhpl.us/~bryan/irc/download-android-malware-from-mediafire.sh | bash 14:01 < kanzure> oh uh, 14:01 < kanzure> well, you should probably redirect the output to some file like malware.dat 14:01 < kanzure> so .. curl http://diyhpl.us/~bryan/irc/download-android-malware-from-mediafire.sh | bash > malware.dat 14:06 < nmz787> http://www.forbes.com/sites/andygreenberg/2012/07/16/hacker-opens-high-security-handcuffs-with-3d-printed-and-laser-cut-keys/ 14:06 < nmz787> he says he wont release CAD for two of the keys, but the article has an image of the key... so combined with that software for using images to reproduce keys... he kind of released it 14:07 < nmz787> downloading here 14:07 < kanzure> congratulations you are now the proud owner of 1.5 GB of android malware, trojans and viruses 14:09 < kanzure> there's also this (165 MB, but included in that): wget --user-agent="blah" "http://www.mediafire.com/file/1ch8uzgd9evcawb/Android-Malware_SortedTYPE-MD5.zip" 14:09 * nmz787 cancelled that download :P 14:09 < kanzure> ooh CarrierIQ-android-blackberry.zip 14:11 < kanzure> http://www.malgenomeproject.org/ 14:11 < kanzure> "In this project, we focus on the Android platform and aim to systematize or characterize existing Android malware. Particularly, with more than one year effort, we have managed to collect more than 1,200 malware samples that cover the majority of existing Android malware families, ranging from their debut in August 2010 to recent ones in October 2011." 14:18 -!- eudoxia [~eudoxia@r186-52-156-56.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 14:19 -!- skorket [~skorket@cpe-24-58-232-122.twcny.res.rr.com] has joined ##hplusroadmap 14:21 < kanzure> "Medre.A is a an AutoCAD worm, written in AutoLISP and is a very unusual piece of malware. It was 14:21 < kanzure> ACAD/Medre.A – 10000′s of AutoCAD files leaked in suspected industrial espionage and the corresponding whitepaper ACAD/Medre.A and ESET technical analysis is here ACAD/Medre.A Technical Analysis" 14:21 < kanzure> http://blog.eset.com/2012/06/21/acadmedre-10000s-of-autocad-files-leaked-in-suspected-industrial-espionage 14:21 < kanzure> http://blog.eset.com/2012/06/21/acadmedre-a-technical-analysis-2 14:21 < kanzure> "ESET reported Peru and neighboring countries as the target but I noticed that one of the samples' (MD5 25c7e10bb537b4265f6144f2cd7f6d95) original name is 未命名1 ( Unnamed 1), so I wonder if some targets/sources were Chinese speaking." 14:22 < kanzure> http://contagiodump.blogspot.com/2012/06/medrea-autocad-worm-samples.html#more 14:25 -!- rdb [~rdb@panda3d/developer/rdb] has left ##hplusroadmap [] 14:28 -!- skorket [~skorket@cpe-24-58-232-122.twcny.res.rr.com] has quit [Quit: Leaving] 14:31 -!- eudoxia [~eudoxia@r186-52-156-56.dialup.adsl.anteldata.net.uy] has quit [Quit: Leaving] 14:35 < nmz787> David House Grand Jury Notes http://pastebin.com/q0hTkwFh 14:37 -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has quit [Ping timeout: 250 seconds] 14:38 < nmz787> "I notice you are taking notes. Attempting to create your own transcript is a violation of rule 6(e) of this grand jury." 14:38 < kanzure> oh noes 14:44 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 14:46 -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has joined ##hplusroadmap 15:04 -!- klafka [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has quit [Quit: Computer has gone to sleep.] 15:08 -!- nmz787 [~Nathan@173-163-203-241-Richmond.hfc.comcastbusiness.net] has quit [Quit: Leaving.] 15:34 -!- shin-to [~shin-to@ulmg-5d84dc3c.pool.mediaWays.net] has quit [Quit: systems shutting down_shin-to is entering sleepmode] 15:37 -!- cpopell [ad42e490@gateway/web/freenode/ip.173.66.228.144] has joined ##hplusroadmap 15:42 < kanzure> cpopell: have you considered using an actual irc client for once 15:42 < kanzure> like, i'd expect you'd be the type of person who would like mibbit 15:42 < cpopell> But I like virc and it doesn't work on win7 >_> 15:43 < kanzure> you keep logging in from the freenode thing 15:43 < cpopell> yeah 15:43 < cpopell> shrug 16:05 < kanzure> "You chose to format sda1 to ext3. All data in that partition will LOSE." 16:06 < kanzure> cfdisk has weird grammar 16:10 < Sanqui> it's to make you read it twice 16:12 < kanzure> wow, android-x86 runs much more smoothly than the other emulated junk 16:12 < AdrianG> any android x86 devices 16:14 < AdrianG> ? 16:15 < kanzure> yes they've been out for a few years 16:34 -!- chevbird [~chevbird@209-6-62-26.c3-0.sbo-ubr1.sbo.ma.cable.rcn.com] has joined ##hplusroadmap 16:55 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 17:12 < AdrianG> are there any virtualbox VMs you can download with android x86 on it? 17:12 < kanzure> i'm playing with qemu and android-x86-4.0-RC2-eeepc.iso 17:25 < AdrianG> ic 17:57 < kanzure> hrm the "Behavior Genetics Association" site is supposed to have a mailman installation, anyone have the link? 17:59 -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap 18:04 < kanzure> hmmm i am getting recruiting emails out the gazoo today 18:04 < kanzure> box.net, airbnb, rockmelt (uughhh) all within 30 minutes 18:10 < kanzure> "The 1,000 Genomes Project now at 130 TB and growing" 18:11 < kanzure> "The Human Microbiome Project now at 10 TB and growing" 18:11 < kanzure> "NASA's Solar Observatory: 1.6 TB per day" 18:11 < kanzure> "CERN's LHD: 60 TB per day" 18:11 < kanzure> "Large Synoptic Survey Telescope: 140 TB per day" 18:11 < kanzure> "Square Kilometer Array: 480 PB per day" 18:36 < gnusha> nanoengineer.git: 2237b68 add chroot instructions to README.md 18:39 < kanzure> gnusha: poke 18:39 < kanzure> i guess nanoengineer.git is missing the postreceive hook 18:39 -!- Thorbinator1 [~Thorbinat@c-67-166-146-169.hsd1.ca.comcast.net] has joined ##hplusroadmap 18:39 -!- Thorbinator [~Thorbinat@c-67-166-146-169.hsd1.ca.comcast.net] has quit [Ping timeout: 244 seconds] 18:39 < kanzure> https://github.com/kanzure/nanoengineer/commit/2237b682db2b0c55be81eee747a588b2e073bf0b 18:40 -!- cpopell [ad42e490@gateway/web/freenode/ip.173.66.228.144] has quit [Ping timeout: 245 seconds] 18:40 < kanzure> ah he's just slow. 18:40 < kanzure> i guess that might be ikiwiki's fault or something 18:40 -!- AlonzoTG [~atg@dsl092-168-049.wdc2.dsl.speakeasy.net] has quit [Ping timeout: 244 seconds] 18:40 -!- AlonzoTG [~atg@dsl092-168-049.wdc2.dsl.speakeasy.net] has joined ##hplusroadmap 18:41 -!- Netsplit *.net <-> *.split quits: bkero 18:44 < kanzure> oh look it's perry https://github.com/pmetzger 18:45 < kanzure> he wants to start a facebook group, but so far his only content is me -_- 18:45 < kanzure> https://www.facebook.com/groups/359005944168966/ 18:46 -!- Netsplit over, joins: bkero 18:55 -!- azonenberg [~azonenber@2001:470:888b:2:206:70ff:fe01:46] has quit [Ping timeout: 245 seconds] 19:18 -!- azonenberg [~azonenber@2001:470:888b:2:206:70ff:fe01:46] has joined ##hplusroadmap 19:34 -!- superkuh [~superkuh@unaffiliated/superkuh] has quit [Quit: the neuronal action potential is an electrical manipulation of reversible abrupt phase changes in the lipid bilayer] 21:08 -!- qnm_ [~robsharp@203.48.101.90] has joined ##hplusroadmap 21:13 -!- nmz787 [~Nathan@173-163-203-241-Richmond.hfc.comcastbusiness.net] has joined ##hplusroadmap 21:27 -!- qnm__ [~robsharp@203.48.101.90] has joined ##hplusroadmap 21:27 -!- qnm_ [~robsharp@203.48.101.90] has quit [Read error: Connection reset by peer] 21:28 -!- lichen_ [~lichen@c-24-21-206-64.hsd1.or.comcast.net] has joined ##hplusroadmap 21:30 -!- lichen [~lichen@c-24-21-206-64.hsd1.or.comcast.net] has quit [Ping timeout: 240 seconds] 21:36 -!- qnm__ [~robsharp@203.48.101.90] has quit [Quit: Ex-Chat] 21:43 -!- qnm_ [~robsharp@203.48.101.90] has joined ##hplusroadmap 21:47 -!- qnm__ [~robsharp@203.48.101.90] has joined ##hplusroadmap 21:47 -!- qnm_ [~robsharp@203.48.101.90] has quit [Client Quit] 21:51 -!- qnm__ [~robsharp@203.48.101.90] has quit [Client Quit] 21:51 -!- sylph_mako [~mako@86.38.252.27.dyn.cust.vf.net.nz] has joined ##hplusroadmap 21:53 -!- qnm_ [~robsharp@203.48.101.90] has joined ##hplusroadmap 21:53 -!- qnm_ [~robsharp@203.48.101.90] has quit [Read error: Connection reset by peer] 22:12 -!- qnm_ [~robsharp@203.48.101.90] has joined ##hplusroadmap 22:12 -!- qnm_ [~robsharp@203.48.101.90] has quit [Read error: Connection reset by peer] 22:23 -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Quit: Computer has gone to sleep.] 22:34 -!- devrandom [~devrandom@gateway/tor-sasl/niftyzero1] has joined ##hplusroadmap 23:15 -!- azonenberg [~azonenber@2001:470:888b:2:206:70ff:fe01:46] has quit [Ping timeout: 245 seconds] 23:20 -!- azonenberg [~azonenber@2001:470:888b:2:206:70ff:fe01:46] has joined ##hplusroadmap 23:21 -!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap --- Log closed Wed Jul 18 00:00:12 2012