--- Log opened Mon Mar 25 00:00:02 2013 --- Day changed Mon Mar 25 2013 00:00 -!- cpopell [~cpopell@pool-96-231-37-73.washdc.fios.verizon.net] has joined ##hplusroadmap 00:04 -!- Helleshin [~talinck@69-61-156-24.ubr1.dyn.lebanon-oh.fuse.net] has quit [Ping timeout: 252 seconds] 00:05 -!- klafka [~klafka@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Remote host closed the connection] 00:06 -!- Helleshin [~talinck@69-61-156-24.ubr1.dyn.lebanon-oh.fuse.net] has joined ##hplusroadmap 00:15 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has quit [Read error: Connection reset by peer] 00:16 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has joined ##hplusroadmap 00:31 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 245 seconds] 00:33 < kanzure> win 31 00:33 < kanzure> gah. 00:33 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has quit [Read error: Connection reset by peer] 00:34 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has joined ##hplusroadmap 00:39 < Swordsman> eh? win3.1? 00:39 < kanzure> no. irssi input error. 00:40 < Swordsman> ah. 00:42 < Swordsman> I seem to keep bumping into transhumanism, heh 00:42 < Swordsman> like, over the last decade 00:43 < Swordsman> the stuff on the wiki is quite relevant to my interests 00:44 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 00:44 < Swordsman> specifically, I've been interested in artificial intelligence since I was a kid 00:45 < Swordsman> and what's actually physically going on under the hood, when it comes to human thought processes 00:46 < Swordsman> I figure that that sort of information won't be accessible until technology advances quite a bit further though, so I'm more interested in trying to push technology forward because I've been curious for so long 00:47 < Swordsman> I used to read yudkowsky, which got me into lesswrong / overcomingbias, then I forgot about it for a while 00:47 < Swordsman> and now here I am again, entirely by accident 00:48 < kanzure> oh i see "In that system, a servo motor rotates the battery case in order to cause shear in the magnets and allow battery disengagement from the UAV." 00:49 < Swordsman> basically what I'm trying to focus on right now is... I want to see if I can figure out a way for people to build high performance circuits, at low cost, easily, at home 00:49 < kanzure> Swordsman: i wouldn't put much stock in eliezer's operations. 00:50 < Swordsman> I've got most of the model in my head already, there's just one, maybe two more steps left in it 00:50 < kanzure> Swordsman: furthermore, most of the recent results seem to be coming from brain emulation ("let's use science to inform what we do on computers") rather than artificial intelligence labs. 00:51 -!- Coornail_ is now known as Coornail 00:52 < Swordsman> yeah 00:52 < kanzure> http://diyhpl.us/~bryan/papers2/brain-emulation-roadmap-report.pdf 00:52 < Swordsman> I'm not so interested in simulating artificial intelligence 00:53 < Swordsman> I want to come up with ways to mass develop cheap high performance circuits that will make it easier to process large amounts of data, including experimental results from things like brain simulations, eeg scans, etc. 00:53 < kanzure> cheapest way is to own the factory 00:54 < kanzure> http://code.google.com/p/homecmos 00:54 < Swordsman> ah, awesome 00:54 < Swordsman> gonna read through, one sec 00:55 < kanzure> but honestly you can get good performance out of ec2 anyway. 00:55 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has quit [Read error: Connection reset by peer] 00:56 < Swordsman> hmm, well, I think the idea I have in mind might get closer to the nm scale 00:56 < Swordsman> but, this is great, thanks 00:57 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has joined ##hplusroadmap 00:57 < Swordsman> well, I also like to tinker with stuff 00:57 < Swordsman> and I'd like to be able to come up with a design that'd be extremely easy and safe for anyone 00:58 < Swordsman> I'm thinking about going espcially for a reconfigurable system design, so that peple don't have to do all the hardware engineering aspects, they can just reload a new config onto the same hardware 00:59 < kanzure> paperbot: http://xs3d.kaist.ac.kr/paperdata/2011/2011-JIRS-Morrison-UAV%20bat%20replace-Online%20First.pdf 01:00 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/5328bb92cefa879e87a1f55ccb3667c9.pdf 01:00 < Swordsman> and I've pretty much got this worked out... I have this method in mind that I used to use for transforming memory layouts to compensate for various gpu memory sublties back when I was doing game dev 01:01 < Swordsman> it's really quite simple and straightforward 01:02 < Swordsman> so if I can just figure out a way to translate a few rigid square arrays of elements relative to eachother while keeping them intact, then it'll work 01:02 < Swordsman> whether it's folding them, or stacking them, or whatever 01:04 < Swordsman> the end result would be that anyone would be able to make their own cpu / gpu at home, and scale it up as much as they like, for very little cost 01:07 < Swordsman> so yeah, that's what I'm trying to do 01:08 < Swordsman> it's slightly similar to photolithography methods, but it'd remove all the NRE costs 01:10 -!- xmj [~xmj@copyfree/advocate/xmj] has left ##hplusroadmap [] 01:11 < Swordsman> which might not be much got the μm level, but it gets pretty high as you get closer to nm 01:12 < Swordsman> got = at 01:12 -!- Viper168_ [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 01:13 < Swordsman> like, you're looking at anywhere from $100k to $500m, I gues 01:13 < Swordsman> er, guess 01:13 < Swordsman> unless if you're going with electron beam lithography, which is painfully slow 01:14 < Swordsman> and still requires some expensive equipment, so it wouldn't be accessible to everyone 01:15 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 264 seconds] 01:15 -!- klafka [~klafka@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap 01:18 < Swordsman> in addition, it could probably produce fully 3d circuits 01:20 -!- klafka [~klafka@c-24-6-18-31.hsd1.ca.comcast.net] has quit [Ping timeout: 245 seconds] 01:22 < Swordsman> there're other advantages it might also have, but I'm not 100% SURE ABOUT THOSE YET 01:22 < Swordsman> caps 01:23 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has quit [Read error: Connection reset by peer] 01:23 < Swordsman> but in terms of diy computational hardware at virtually no cost, I'm pretty certain about that 01:24 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has joined ##hplusroadmap 01:27 < Swordsman> oh, hm. 01:28 < Swordsman> I think I just had an idea for how this might work, actually 01:30 < Swordsman> anyway, if I do manage to get this working, I'll bring you guys the details of how to put it all together, since I can see it being helpful with some of the various nanotech stuff on the wiki 01:30 < Swordsman> if you want, anyway 01:32 < Swordsman> I'm still new to this so maybe I'm missing something, heh 01:32 < Swordsman> but... yeah 01:32 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 264 seconds] 01:34 -!- zdap [~not@bas5-kingston08-1242447600.dsl.bell.ca] has joined ##hplusroadmap 01:34 -!- Coornail_ [~Coornail@li66-97.members.linode.com] has joined ##hplusroadmap 01:34 -!- rigel [~pi@c-76-105-237-98.hsd1.or.comcast.net] has joined 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[~Qfwfq@unaffiliated/washirving] has quit [Ping timeout: 245 seconds] 02:58 -!- Qfwfq [~Qfwfq@175.156.178.100] has joined ##hplusroadmap 02:58 -!- Qfwfq [~Qfwfq@175.156.178.100] has quit [Changing host] 02:58 -!- Qfwfq [~Qfwfq@unaffiliated/washirving] has joined ##hplusroadmap 03:08 < archels> paperbot handles filenames correctly now? 03:08 < archels> paperbot: http://turingbirds.com/temp/Dielectric%20properties%20of%20tissues%20and%20biological%20materials%20-%20a%20critical%20review_Foster,%20Schwan_Crit.%20Rev.%20Biomedical%20Eng.%20Vol%2017,%20Issue%201%20(1989).pdf 03:09 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/73d9a3b4c7bf9c8f525712ac66c0e46d.pdf 03:13 -!- Qfwfq [~Qfwfq@unaffiliated/washirving] has quit [Ping timeout: 240 seconds] 03:13 < archels> no :( 03:13 -!- Qfwfq [~Qfwfq@unaffiliated/washirving] has joined ##hplusroadmap 03:14 < archels> kanzure: still looking for a good place to post this paper that I scanned ^ 03:23 -!- pad2 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[~ielo@host-2-97-162-156.as13285.net] has quit [Ping timeout: 256 seconds] 04:51 < kanzure> http://biotinkering.org/ http://www.raumfahrtagentur.org/ 05:01 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has joined ##hplusroadmap 05:01 -!- zdap [~not@bas5-kingston08-1242447600.dsl.bell.ca] has quit [Read error: Connection reset by peer] 05:16 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has quit [Read error: Connection reset by peer] 05:17 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has joined ##hplusroadmap 05:22 -!- gene_hacker [~chatzilla@cpe-70-113-95-55.austin.res.rr.com] has quit [Quit: ChatZilla 0.9.90 [Firefox 19.0.2/20130307023931]] 05:23 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Remote host closed the connection] 05:29 -!- archbox_ [~archie@unaffiliated/archbox] has quit [Ping timeout: 256 seconds] 05:31 -!- OldCoder_ [~OldCoder_@c-69-181-139-128.hsd1.ca.comcast.net] has quit [Quit: Leaving] 05:34 -!- archbox_ 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-!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap 09:08 -!- Mariu [Jimmy98@89.41.57.33] has quit [Ping timeout: 248 seconds] 09:22 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap 09:37 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 245 seconds] 09:50 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 09:58 -!- augur [~augur@208.58.5.87] has quit [Remote host closed the connection] 10:17 -!- Mariu [Jimmy98@89.41.57.33] has joined ##hplusroadmap 10:23 -!- klafka [~klafka@204-16-157-18-static.ipnetworksinc.net] has joined ##hplusroadmap 10:35 -!- augur [~augur@129-2-129-33.wireless.umd.edu] has joined ##hplusroadmap 10:37 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 245 seconds] 10:42 < kanzure> archels: because often the url has a terrible string that would not be useful 10:47 < kanzure> hmm http://www.opensourcewarehouse.org/contributing-to-the-oshw-doc-jam-from-all-over-the-world-plus-confirmed-location/ 10:47 < kanzure> god damn it, more google docs. what happened to just putting a file in a repository. 10:49 < kanzure> this is the lamest shit i've seen in a while. 10:49 < kanzure> yeah ok these people are clueless. 10:51 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 11:04 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has quit [Read error: Connection reset by peer] 11:05 -!- pad2 [~not@bas5-kingston08-1242447600.dsl.bell.ca] has joined ##hplusroadmap 11:09 < kanzure> https://developer.etrade.com/ctnt/dev-portal/getDetail?contentUri=V0_Documentation-MarketAPI-GetQuotes 11:09 < kanzure> dunno if i prefer quantopian.com or not.. 11:09 < kanzure> or IB. 11:11 -!- He||eshin is now known as Helleshin 11:19 -!- audy [~audy@heyaudy.com] has quit [Changing host] 11:19 -!- audy [~audy@unaffiliated/audy] has joined ##hplusroadmap 11:20 -!- Sanky_ is now known as Sanky 11:23 < archels> kanzure: this is only for when extracting the title from the json object has failed 11:23 < archels> how about this format: "[hostname] filename.pdf" 11:23 < archels> e.g. [iopscience.iop.org] 1741-2552_9_5_056007.pdf 11:24 < archels> which is still a little better than 499998c9cf42322c2029b6a7a0a38a54.pdf 11:24 < kanzure> if you submit a patch then i will merge it in and we can test it for a while. 11:25 < archels> that involves actually setting up phenny somewhere :\ 11:25 < kanzure> not entirely 11:25 < kanzure> it works without phenny 11:25 < kanzure> it doesn't even import anything phenny-related. 11:26 < archels> right, just call it from the ipython shell or so? 11:26 < kanzure> yes 11:26 < kanzure> also if you are feeling super helpful, then you could write some unit tests. 11:28 -!- eudoxia [~eudoxia@r190-134-69-60.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 11:28 < eudoxia> < kanzure> god damn it, more google docs. what happened to just putting a file in a repository. 11:28 < eudoxia> the OSE wiki is worse 11:28 < eudoxia> a bajillion embedded things from a million different places 11:29 < eudoxia> tables, files and pictures for every page are split among at least a dozen different google docs sort of things, timeline and slides plugins, some of which don't even work anymore 11:29 < kanzure> "oh we'll just use semantic mediawiki! everything will be ok!" noooot. 11:30 < klafka> someone needs to make a wiki implementation that doesn't suck 11:30 < kanzure> ikiwiki 11:31 < klafka> actually ok tnhat would be nice a wiki that ran and set itself up off an ami automagically 11:31 < eudoxia> http://opensourceecology.org/wiki/Global_Village_Construction_Set embedded TED and vimeo 11:31 < eudoxia> http://opensourceecology.org/wiki/CEB_Press embedded google docs 11:31 < kanzure> klafka: ikiwiki is very close to running straight out of an ami. sudo apt-get install ikiwiki. 11:31 < eudoxia> and what the fuck is that cooliris thing 11:31 < klafka> oh nice 11:31 < kanzure> or you could install jrayhawk's piny packages. 11:31 < kanzure> this was the point of making diyhpl.us/wiki use git but it seems to be lost on everyone. 11:32 < eudoxia> frankly i've finally realized why kanz was right all along and a bunch of markdown files in a git repo beat the shit out of everything else 11:32 < eudoxia> oh and they have an issuu plugin too 11:32 -!- nsh is now known as tWoah 11:32 < kanzure> it is not useful being right if people only realize it 5 years later 11:32 -!- tWoah is now known as nsh 11:34 < eudoxia> i like the cover on this http://opensourceecology.org/wiki/2012_Annual_Report 11:35 < jrayhawk> i think gitit is probably okay too but i haven't really played with it 11:38 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 245 seconds] 11:38 < kanzure> reprap.org suffers from an almost similar problem. sebastien is good at getting people to use the wiki but mediawiki is awful. 11:43 < brownies> github's markdown-wikis are pretty idiot-proof. it'd be nice to just have those standalone 11:43 < kanzure> there are some gems that do that 11:43 < kanzure> and they are already clonable 11:46 -!- archels [~neuralnet@sascha.esrac.ele.tue.nl] has quit [Read error: Operation timed out] 11:48 -!- archels [~neuralnet@sascha.esrac.ele.tue.nl] has joined ##hplusroadmap 11:50 < nmz787_> http://www.youtube.com/watch?v=Tlas4vQTp8E 11:50 < nmz787_> .title 11:50 < yoleaux> Is China Engineering Smarter Babies? - YouTube 11:50 < nmz787_> i'm banned somewhere? 11:51 < nmz787_> ##electronics Cannot change nickname while banned on channel 11:52 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 11:55 -!- nmz787_ is now known as nmz787 11:59 -!- cpopell [~cpopell@pool-96-231-37-73.washdc.fios.verizon.net] has joined ##hplusroadmap 12:00 < eudoxia> i am rather disappointed that nobody sells watches with Unix time 12:01 < nmz787> i guess this is the 'original' article http://www.vice.com/read/chinas-taking-over-the-world-with-a-massive-genetic-engineering-program 12:02 < nmz787> reall though it's just selection 12:02 < nmz787> the research is in what's interesting to select for 12:02 -!- eudoxia [~eudoxia@r190-134-69-60.dialup.adsl.anteldata.net.uy] has quit [Quit: leaving] 12:05 < kanzure> nmz787: ##electronics requires you to be registered to join 12:05 < kanzure> registered and authenticated 12:11 < ParahSailin> good for china-- first country in the world to eradicate Down's syndrome, a completely preventable congenital disorder 12:24 < nmz787> ParahSailin: that's been done already? 12:27 < ParahSailin> i figured thats what your link above was referencing 12:27 < nmz787> no BGI is sequencing smart people and looking for similarities 12:27 < nmz787> then using that info to select IVF candidates 12:27 < ParahSailin> ah 12:28 < ParahSailin> one child policy has been strong incentive to abort when chromosomal abnormalities are detected 12:30 -!- augur [~augur@129-2-129-33.wireless.umd.edu] has quit [Remote host closed the connection] 12:30 < nmz787> local couple sues hospital for 'wrongful birth' when prenatal scan fails to mention down syndrome http://www.oregonlive.com/portland/index.ssf/2012/03/portland_couple_sues_legacy_he.html 12:32 < ParahSailin> damn, mosaic downs 12:38 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 245 seconds] 12:43 < kanzure> "How come +Bryan Bishop is such a genius and still doesn't have a Nobel Prize or something?" 12:43 < kanzure> what the hell internet 12:43 < kanzure> so i am a nobel prize winning fbi agent ?? 12:43 < kanzure> i am so conflicted 12:49 < nmz787> who said that? 12:50 < kanzure> someone on googleplus; i just get alerts. 12:50 < nmz787> damn dude 12:50 < nmz787> no one says i deserve a nobel 12:50 < nmz787> that i know of 12:50 < nmz787> i say congrats to internet famedom 12:51 < kanzure> tell you what. i'll put in a word for you. 12:51 < kanzure> nobel prizes for everyone! 12:51 < kanzure> i think zuck's prize is cooler though. 12:51 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 12:52 < kanzure> this one http://www.breakthroughprizeinlifesciences.org/ 12:52 < kanzure> "The Breakthrough Prize in Life Sciences is founded by Art Levinson, Sergey Brin, Anne Wojcicki, Mark Zuckerberg and Priscilla Chan, and Yuri Milner to recognize excellence in research aimed at curing intractable diseases and extending human life" 12:52 < kanzure> "Founding sponsors of the Breakthrough Prize in Life Sciences include Sergey Brin and Anne Wojcicki, Mark Zuckerberg and Priscilla Chan, and Yuri Milner, who collectively have agreed to establish 5 annual prizes, US$3 million each, going forward." 12:54 < klafka> yeah that's pretty cool 12:59 < nmz787> bah 13:00 < nmz787> SF isn't exactly switzerland or norway or sweden (wherever the nobel thing is from) 13:02 < kanzure> has the nobel prize award money kept with inflation? 13:02 < nmz787> i never really thought it was about the money 13:02 < kanzure> lots of scientists are broke, the money helps. 13:03 < kanzure> "The purse has increased since the 1980s, when the prize money was 880 000 SEK ($350,000 USD ish in 2007-2012 money)" 13:03 < kanzure> "In 2009, the monetary award was 10 million SEK ($1.4 million USD)" 13:03 < kanzure> "In June 2012, it was lowered to 8 million SEK" huh 13:06 < kanzure> there seems to be a "new lab equipment" bias in nobel prizes (which is okay, just an interesting trend). i wonder if that will happen with zuck's fund. 13:06 < nmz787> what do you mean 13:06 < nmz787> against buying new equipment? 13:06 < nmz787> against buying new equipment? 13:07 < kanzure> biased towards awarding to individuals who have built new types of lab equipment 13:07 < kanzure> positive-bias 13:07 < nmz787> lab companies donating the $ 13:07 < nmz787> ? 13:07 < kanzure> no 13:07 < kanzure> a bias does not necessarily mean corruption 13:08 < kanzure> for instance, there were prizes awarded for the work involved in constructing or resulting from the construction of the electron microscope, thermocycler, etc. 13:08 < kanzure> and polypeptide synthesizers. 13:10 -!- augur [~augur@208.58.5.87] has joined ##hplusroadmap 13:12 < ParahSailin> there was a nobel prize for thermocycler? 13:13 < kanzure> kary mullis 13:13 < kanzure> http://www.nobelprize.org/nobel_prizes/chemistry/laureates/1993/press.html 13:13 < kanzure> "with half to Dr Kary B. Mullis, La Jolla, California, U.S.A., for his invention of the polymerase chain reaction (PCR) method," 13:15 < kanzure> "Session One (May 14-15, 1992), was recorded at Cetus Corporation, Emeryville, California. Kwok, Sninsky, Saiki, Scharf, Leath, Widunas, Jones, Watson, Respess, Erlich, Gelfand, Mullis and Faloona discussed the invention of the PCR technique, early applications, and development of technologies for automating the process, c. 1980-1992, including:" 13:15 < kanzure> "invention of the pcr technique; design and engineering of automated thermocycling machines; development of commercial thermocycling instruments;" 13:16 < kanzure> "operations of Mr. Cycle, the first generation cycling machine; demonstrations of the second- and third-generation thermocycling machines; Perkin-Elmer TC 4800 and 9600 thermocyclers; demonstration of the gel electrophoreses process using the TPCR 9600; gel from first successful experiment;" 13:16 < kanzure> haha first successful gel... that's going a bit far. 13:16 < kanzure> confirmation is important but i dunno about mounting the gel on the wall or something. 13:16 < nmz787> ahh, i thought you meant bias for how a winner spent the money 13:18 < kanzure> i wonder if that video session is on youtube 13:20 < kanzure> damn. no. 13:20 < kanzure> "The first thermocycling machine, "Mr. Cycle" was developed by Cetus engineers to address that need to add fresh enzyme to each test tube after the heating and cooling process. And the purification of the Taq polymerase resulted in the need for a machine to cycle more rapidly among different temperatures. In 1985, Cetus formed a joint venture with the Perkin-Elmer Corporation in Norwalk, Connecticut, and introduced the DNA Thermal Cycler." 13:21 < kanzure> "By 1988, Cetus was receiving numerous inquiries about licensing to perform PCR for commercial diagnostic purposes. On January 15, 1989, Cetus announced an agreement to collaborate with Hoffman-LaRoche on the development and commercialization of in vitro human diagnostic products and services based on PCR technology. Roche Molecular Systems eventually bought the PCR patent and associated technology from Cetus for $300,000,000." 13:21 < kanzure> "Ramunas Kondratas, curator at the Smithsonian's National Museum of American History (NMAH), documented the discovery, development, commercialization, and applications of PCR technology. Three sessions were recorded May 14 and May 15, 1992 at Emeryville, California; September 25, 1992 at Alameda, California; and February 25, 1993 at Norwalk, Connecticut." 13:21 < nmz787> paperbot: http://www.sciencedirect.com/science/article/pii/S0197458004001411 13:21 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Contribution%20of%20the%20MTHFR%20gene%20to%20the%20causal%20pathway%20for%20depression%2C%20anxiety%20and%20cognitive%20impairment%20in%20later%20life.pdf 13:24 < kanzure> http://en.wikipedia.org/wiki/Stanford_v._Roche "Stanford v. Roche, 563 U.S. ___ (2011), was a United States Supreme Court case in which the Court held that title in a patented invention vests first in the inventor, even if the inventor is a researcher at a federally funded lab subject to the 1980 Bayh–Dole Act.[1] The judges affirmed the common understanding of US Constitutional law that inventors originally own inventions they make, and ... 13:24 < kanzure> ... contractual obligations to assign those rights to third parties are secondary.[2]" 13:24 < kanzure> (different patents) "When Stanford sued Roche for infringing the patents in 2005, Roche countered by claiming that it jointly owned the patents, due an agreement that a Stanford faculty member, Dr. Mark Holodniy, signed in the late 1980s when he did research at Cetus, the biotechnology company that invented PCR and that was later acquired by Roche." 13:24 < kanzure> "When Holodniy had joined the faculty of Stanford shortly before he had visited Cetus, he, like all scientific personnel at companies and research institutions, had signed an agreement in which he agreed that his employer would own any inventions he made. Stanford's agreement, in particular, stated that he "'agree[d] to assign' to Stanford his 'right, title and interest in' inventions resulting from his employment at the University."[1]:2" 13:24 < kanzure> "The Stanford lab in which Holodniy worked had been working on developing better HIV tests, and wanted to try the new PCR method, so Holodniy's supervisor had arranged for him to work at Cetus to learn the technique. .. After completing his training at Cetus, Holodniy then returned to Stanford where he and other Stanford employees tested the HIV measurement technique. Over the next few years, Stanford obtained written assignments of rights ... 13:24 < kanzure> ... from the Stanford employees, including Holodniy, and filed several patent applications related to the procedure." 13:24 < kanzure> hah. 13:25 < kanzure> that seems to be the same cetus that commercialized the first thermocycler 13:25 < kanzure> "the new PCR method" probably refers to kary mullis' pcr method and not a particular variation 13:27 < kanzure> oh i didn't know kary mullis was working for cetus when he patented it. that's curious. 13:27 < kanzure> "Dr. Kary Mullis at Cetus Corporation conceives of Polymerase Chain Reaction (PCR). PCR is a simple yet elegant process that enables the production of virtually unlimited copies of genetic material in the laboratory." 13:28 < kanzure> "Although the Nobel Prize for the conception of PCR was given to Kary Mullis, Ph.D., in 1993, the technology was developed and applied by the labs of Henry Erlich, Ph.D., David Gelfand, Ph.D., and other teams of scientists at Cetus. The full history of the technology’s development and application is marked by an extraordinary collaboration of scientists working in a corporate setting." 13:30 < kanzure> pfft there's a patent on the pcr microcentrifuge tube http://www.google.com/patents/US6015534 issued in 2000 (seems sorta late for that) 13:33 < kanzure> "On Monday, March 27, 1989, a U.S. federal trademark registration was filed for DNA THERMAL CYCLER by Perkin-Elmer Corporation, The, NORWALK 068590181. The USPTO has given the DNA THERMAL CYCLER trademark serial number of 73789096. The current federal status of this trademark filing is ABANDONED-FAILURE TO RESPOND OR LATE RESPONSE." 13:34 < kanzure> man all those patents on pcr are really sad. their claims seem to overlap a lot and none of the patent examiners are the same people. 13:38 -!- archbox_ [~archie@unaffiliated/archbox] has quit [Read error: Connection reset by peer] 13:40 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 264 seconds] 13:42 < ParahSailin> ah i didnt realize the thermocycler was included in the PCR nobel 13:43 < kanzure> well.. pcr definitely came first before any machines, but it was the same people. the award text also does not specifically point to the machine either. but they are both strongly related i think. 13:48 -!- qu-bit_ [~shroedngr@unaffiliated/barriers] has joined ##hplusroadmap 13:51 -!- qu-bit [~shroedngr@unaffiliated/barriers] has quit [Ping timeout: 260 seconds] 13:53 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 14:21 < ParahSailin> i would hope that any invention would imply some sort of physical manifestation 14:26 < kanzure> i think they had some patents on the protocols themselves. 14:29 -!- Urchin[emacs] [~user@unaffiliated/urchin] has joined ##hplusroadmap 14:32 -!- archbox_ [~archie@unaffiliated/archbox] has joined ##hplusroadmap 14:40 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 256 seconds] 14:46 < ParahSailin> i wonder when sperm sexing will become popular for the chinese ultra-rich 14:47 < ParahSailin> sperm sexing takes huge bull loads to get enough to knock up a cow, but it probably wouldnt cost that much more to accurately sort smaller amounts 14:53 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 15:11 < kanzure> nmz787: cathal's response is pretty funny. he seems to have a very negative opinion of gamete modification. 15:38 -!- superkuh [~superkuh@unaffiliated/superkuh] has quit [Quit: more partitioning] 15:40 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 256 seconds] 15:54 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 16:15 < nmz787> kanzure: yeah or we're just non-ethical? too logical? 16:21 < kanzure> i don't think his opinion is tractable. if you took his opinion to its conclusions then it would mean something like "people should not be allowed to think about who they breed with". 16:21 < kanzure> btw randalla1ordon is also idling in here 16:23 < nmz787> ahh 16:24 < nmz787> the real question was regarding the country with most progressive laws (or most lax) 16:25 < ParahSailin> technology is way too primitive to do any useful gamete modification 16:26 < nmz787> seems like that's because there are too many people scared of god to even start trying 16:27 < ParahSailin> no, there's not even decent technology to do useful transfection of cell lines in dishes 16:27 < nmz787> how do we have whole lines of mice knockouts? 16:27 < nmz787> gfp mice, etc 16:27 < nmz787> ? 16:28 < ParahSailin> for some value of "useful" 16:28 < ParahSailin> its possible to knock out a gene or put one in 16:28 < ParahSailin> there are uses in a lab for that 16:28 < ParahSailin> there's nothing that would be useful in the context of eugenics that can be done at our current technology 16:29 < nmz787> gfp baby 16:29 < ParahSailin> exactly 16:31 < ParahSailin> i dont think there's even a way to do a snp recombination transfection 16:31 < nmz787> or actually lux 16:31 < ParahSailin> much less a dozen snps at a time to be useful in eugenics 16:32 < ParahSailin> much less the ability to modify regulatory elements or predict the effects of that 16:33 < ParahSailin> of course cathal believes its unethical to eat animals, so why are we paying attention to his ethical theories 16:35 < nmz787> i consider his opinion, he's usually pretty smart about things it seems 16:36 < nmz787> how else would i bust into a new paradigmn, if i don't question my own? 16:37 < kanzure> i think you can do genome assembly if you are willing to pay a lot 16:38 < kanzure> ParahSailin: i don't presently remember cathal's stance on gmo food either. since he's european, i imagine it's negative. i would expect given his biology background that it would be less negative. yet, seeing his responses here indicates that i am completely unable to predict his opinion. 16:41 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 264 seconds] 16:54 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 16:55 < nmz787> well if you were able to predict what he were to say, you'd not hear anything new from him ever 17:00 -!- randalla1ordon is now known as randallagordon 17:05 -!- BioGuy [~BioGuy@c-24-21-160-77.hsd1.or.comcast.net] has joined ##hplusroadmap 17:11 -!- gedanken1tuecke [~bastian@phylomemetic-tree.de] has quit [Ping timeout: 264 seconds] 17:13 -!- gedankenstuecke [~bastian@phylomemetic-tree.de] has joined ##hplusroadmap 17:13 -!- klafka [~klafka@204-16-157-18-static.ipnetworksinc.net] has quit [Remote host closed the connection] 17:14 -!- yorick [~yorick@oftn/member/yorick] has quit [Remote host closed the connection] 17:16 < kanzure> BioGuy: hey. 17:16 < BioGuy> Hey! 17:19 -!- gedankenstuecke [~bastian@phylomemetic-tree.de] has quit [Ping timeout: 256 seconds] 17:31 -!- EnLilaSko [EnLilaSko@unaffiliated/enlilasko] has quit [Remote host closed the connection] 17:40 -!- gedankenstuecke [~bastian@phylomemetic-tree.de] has joined ##hplusroadmap 17:42 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 245 seconds] 17:53 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Remote host closed the connection] 17:54 < ParahSail1n> i thought the euopean opposition to gmo was merely trade war shenanigans 17:55 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 17:57 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 18:08 -!- Urchin[emacs] [~user@unaffiliated/urchin] has quit [Quit: ERC Version 5.2 (IRC client for Emacs)] 18:10 < BioGuy> So, I'm thinking a good starter project for working with Python would be to write a program to search through the ##hplusroadmap logs. So any pythonistas here do you have any suggestions? Can this all be accomplished with the standard library? Which modules would you suggest primarily looking into? 18:11 -!- OldCoder_ [~OldCoder_@209.237.22.146] has quit [Remote host closed the connection] 18:17 -!- eudoxia [~eudoxia@r190-135-25-84.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 18:17 < eudoxia> import os 18:17 < eudoxia> def search(derp): 18:18 < eudoxia> os.system('grep ' + derp + ' *.log') 18:19 < eudoxia> on that note, i've been meaning to write a script that downloads today's log every couple of minutes 18:19 < ParahSail1n> BioGuy, help out with paperbot 18:19 < BioGuy> paperbot? 18:19 < ParahSail1n> paperbot needs to be able to scrape more sites 18:20 < eudoxia> and uses libnotify to search for terms of interest 18:20 < BioGuy> thanks for the tips! 18:20 < ParahSail1n> https://github.com/kanzure/paperbot 18:21 < eudoxia> (correction: it uses libnotify to alert me when it's found something of interest, like when kirka logs on or people start talking about mnt) 18:23 -!- klafka [~klafka@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap 18:24 < BioGuy> paperbot looks interesting, but I'm not sure if I quite understand how it works. 18:24 < BioGuy> hi paperbot 18:24 < BioGuy> Ha! That didn't do anything 18:25 < ParahSail1n> paperbot: http://www.nature.com/nature/journal/v450/n7168/full/nature06325.html 18:25 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/Crystal%20structure%20of%20the%20human%202%20adrenergic%20G-protein-coupled%20receptor.pdf 18:25 < eudoxia> somebody needs to implement .paperbotsnack 18:25 < eudoxia> somebody = kanzure 18:26 < eudoxia> or i guess i could give it a try 18:26 < ParahSail1n> paperbot: http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/191/ra60 18:26 < paperbot> error: HTTP 500 http://diyhpl.us/~bryan/papers2/paperbot/bae2146a588663bdcbc033f0758f14c1.txt 18:26 < ParahSail1n> paperbot: http://stke.sciencemag.org/cgi/content/full/sigtrans;4/191/ra60 18:26 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/eb539b0a9f0223d3a7514f5f5e394599.txt 18:26 < eudoxia> dammit paperbot we're trying to show you off to BioGuy stop failing like that 18:27 < ParahSail1n> no, this is exactly what bioguy needs to see 18:27 < ParahSail1n> on some publishers, paperbot can't scrape 18:28 < BioGuy> HAHA! So if you reference something behind a pay wall it finds an actual copy? 18:28 < BioGuy> ROFL @ ParaSail1n 18:28 < BioGuy> That is really cool! 18:29 -!- klafka [~klafka@c-24-6-18-31.hsd1.ca.comcast.net] has quit [Ping timeout: 240 seconds] 18:29 < ParahSail1n> bioguy yes it is located inside a paywall 18:29 < eudoxia> in an undisclosed location~ 18:30 < BioGuy> so do you manually feed it sites where the article is available or are there "scraper sites" that can find the article? 18:30 < BioGuy> Ahhh 18:30 < eudoxia> you give it the url and it extracts it directly 18:30 < BioGuy> Thats awesome! 18:31 < eudoxia> took me a whole afternoon to figure out how it works 18:33 -!- yashgaroth [~ffffff@cpe-66-27-118-94.san.res.rr.com] has joined ##hplusroadmap 18:34 < BioGuy> paperbot: http://onlinelibrary.wiley.com/doi/10.1002/bip.360340210/abstract 18:34 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/c12baf5c5c7658c41c0110599eff8095.txt 18:35 < BioGuy> paperbot: http://onlinelibrary.wiley.com/doi/10.1002/bip.360340210/pdf 18:35 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/b16020afcae6e58b52694b70b3d627b8.txt 18:36 < ParahSail1n> yeah, wiley doesnt work so good 18:36 < ParahSail1n> try sciencedirect 18:38 < eudoxia> i'm like the only guy here who's never used paperbot, it feels kinda weird 18:38 < eudoxia> alright paperbot, i don't know you and you don't know me, but i think we can make this work 18:38 < eudoxia> paperbot: http://pubs.acs.org/doi/pdfplus/10.1021/nl400542n 18:38 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/57aab5cad8625c8b413baa3d39c069b6.pdf 18:39 < eudoxia> .paperbotsnack 18:39 < eudoxia> i sure hope i don't get droned for this 18:40 < ParahSail1n> BioGuy, another thing you could work on is making it give helpful names for the ones it fetches vs the hex hash stuff 18:40 < ParahSail1n> for a lot, it grabs the names already http://diyhpl.us/~bryan/papers2/paperbot/ 18:41 < BioGuy> paperbot: http://www.sciencedirect.com/science/article/pii/0005278772904261 18:41 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/The%20gel%20electrophoresis%20of%20DNA.txt 18:42 -!- klafka [~klafka@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap 18:42 < BioGuy> I would love to add what I could... but I feel like I'm a bit out of my league. ie I have no idea what hex hash is ---though I do know what hexadecimal is! 18:42 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 264 seconds] 18:43 < ParahSail1n> hash is how dict works 18:43 < eudoxia> i know what a hash is but i don't know where hex comes into play 18:44 < BioGuy> I really want to tell other people about paperbot, but I don't want to get anyone into any copyright legal troubles. 18:45 < BioGuy> Kanzure are you worried about that at all? 18:45 < eudoxia> title = "%0.2x" % random.getrandbits(128) 18:45 < eudoxia> oh so that's what it is 18:56 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 19:02 < ParahSail1n> ah, so not a hash 19:02 -!- eudoxia [~eudoxia@r190-135-25-84.dialup.adsl.anteldata.net.uy] has quit [Quit: Leaving] 19:03 -!- BioGuy [~BioGuy@c-24-21-160-77.hsd1.or.comcast.net] has quit [Ping timeout: 245 seconds] 19:42 -!- juri__ is now known as juri_ 19:43 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 256 seconds] 19:56 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 20:06 -!- qu-bit_ [~shroedngr@unaffiliated/barriers] has quit [Read error: Connection reset by peer] 20:07 -!- qu-bit [~shroedngr@unaffiliated/barriers] has joined ##hplusroadmap 20:21 -!- klafka_ [~klafka@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap 20:24 -!- klafka [~klafka@c-24-6-18-31.hsd1.ca.comcast.net] has quit [Ping timeout: 240 seconds] 20:27 < kanzure> BioGuy: you can use an existing irc log parser, like one of these https://pypi.python.org/pypi?%3Aaction=search&term=irc+log&submit=search 20:29 < kanzure> eudoxia: yes, i just use a random filename when i don't trust the given url. 20:31 -!- qu-bit [~shroedngr@unaffiliated/barriers] has quit [Remote host closed the connection] 20:37 -!- qu-bit [~shroedngr@unaffiliated/barriers] has joined ##hplusroadmap 20:39 -!- qu-bit [~shroedngr@unaffiliated/barriers] has quit [Read error: Connection reset by peer] 20:40 -!- qu-bit [~shroedngr@unaffiliated/barriers] has joined ##hplusroadmap 20:44 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 272 seconds] 20:49 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 20:57 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 21:22 < balrog> paperbot: http://link.springer.com.libproxy.temple.edu/book/10.1007/b100535/page/1 21:22 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/3e22c7ceee8ab858e8bc064ab07e9e0a.txt 21:23 < balrog> paperbot: http://link.springer.com/book/10.1007/b100535/page/1 21:23 < paperbot> error: HTTP 300 http://diyhpl.us/~bryan/papers2/paperbot/9cfd924647c123abd9ee79a7bf562db9.txt 21:33 < kanzure> i have no clue where all these shanghai keep getting my email address from. is this just random spam? 21:33 < kanzure> *shanghai companies 21:33 < kanzure> this time it's "we are a professional producer of tungsten carbide cutters" 21:45 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 272 seconds] 21:57 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 22:21 -!- OldCoder_ [~OldCoder_@c-69-181-139-128.hsd1.ca.comcast.net] has joined ##hplusroadmap 22:31 < klafka_> With $6.5M In Tow, Bina Technologies Wants To Bring Big Data Insight To Genomic Sequencing 22:31 < klafka_> LOL 22:32 < klafka_> no one in genome sequencing is using large amounts of data 22:35 < brownies> there's only 4 letters! how can the data be big! 22:35 -!- Qfwfq [~Qfwfq@unaffiliated/washirving] has quit [Ping timeout: 256 seconds] 22:35 -!- Qfwfq [~Qfwfq@175.156.178.100] has joined ##hplusroadmap 22:35 -!- Qfwfq [~Qfwfq@175.156.178.100] has quit [Changing host] 22:35 -!- Qfwfq [~Qfwfq@unaffiliated/washirving] has joined ##hplusroadmap 22:46 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 272 seconds] 22:49 < kanzure> microryza got into ycombinator? 22:58 < klafka_> oh really? 22:58 < brownies> what the hell do they even do? 22:58 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap 22:58 < klafka_> 'kicstarter for scientific resaerch' 22:58 < klafka_> *research 22:58 < kanzure> bleh 23:00 < klafka_> man so far my scipy.weave code is way faster than numba's auto jit 23:00 < klafka_> now i'm testing it against scipy.spatial.distance.jaccard 23:05 -!- mako [~mako@103-9-42-31.flip.co.nz] has joined ##hplusroadmap 23:06 < klafka_> it's crazy but i think that my shit is faster 23:07 < klafka_> oh yes 23:07 < klafka_> the scipy code is pure python / numpy 23:07 < kanzure> numba is the python/llvm thing? 23:07 < klafka_> yeah 23:07 < klafka_> i'm really dissapointed about numba though 23:07 < klafka_> I think I'm going to post to their list and see if I am doing something wrong 23:07 < kanzure> btw have you used hive or pig? 23:08 < klafka_> no 23:08 < klafka_> we dont' use hadoop and I haven't really had too much interest in setting that hsit up 23:08 < klafka_> shit 23:09 < klafka_> and numexpr won't work with what i'm doing 23:14 < kanzure> wait, why are you working on work things so late 23:16 < brownies> 11pm monday? sounds like regular work hours to me 23:18 < klafka_> kanzure: idk why not? 23:18 < klafka_> i like wor 23:18 < klafka_> k 23:26 < kanzure> not being slave driven? 23:35 < klafka_> nope 23:45 -!- yashgaroth [~ffffff@cpe-66-27-118-94.san.res.rr.com] has quit [Quit: Leaving] 23:46 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has quit [Ping timeout: 272 seconds] 23:48 < kanzure> "You could still use the plain old browser web cache to track users. Send a unique image to each user with a long expiry time with an id embedded in it somewhere, then on the page, simply read the image using javascript/canvas to get the id." 23:53 < kanzure> http://en.wikipedia.org/wiki/HTTP_ETag#Tracking_using_ETags 23:58 -!- lupfantomo [~lupfantom@24-159-24-229.dhcp.jcsn.tn.charter.com] has joined ##hplusroadmap --- Log closed Tue Mar 26 00:00:38 2013