--- Log opened Fri Jan 24 00:00:00 2014
--- Day changed Fri Jan 24 2014
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00:00 < drewbug> Lemminkainen: Hey, my laptop's battery's going to die soon, but I wanted to say thank you. I'm legitimately considering this now, but even if I never do it, I learned a lot. So, thank you.
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01:44 < jrayhawk> you should make a "can i make my cat glow" FAQ
01:45 < jrayhawk> such a thing would be of distressingly high utility in this room
01:52 < blueskin> haha
02:00 < FourFire> "distressingly high utility"
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07:02 < pasky> https://plus.google.com/116220678599902155344/posts/RzWppAJgQdz
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07:22 <@archels> http://turingbirds.com/temp/IMAG0618.jpg
07:23 <@archels> spotted this in the hallway just now
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07:58 <@kanzure> oh good you can heckle anders sandberg for me
07:58 <@kanzure> "boo, when are you building a moon brain"
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09:10 <@kanzure> archels: have you read http://www.jetpress.org/volume5/Brains2.pdf
09:11 <@kanzure> (the physics of information processing superobjects, anders sandberg etc)
09:17 <@archels> no, I found that googling for 'moon brain' though
09:17 <@archels> I should probably read it.
09:17 <@archels> (instead I added Neverness to my wishlist)
09:17 <@kanzure> good call
09:18 <@kanzure> archels: http://heybryan.org/docs/Zindell,%20David%20-%20Neverness%20(v1.0).txt
09:19 <@archels> what does v1.0 refer to?
09:19 <@kanzure> whoever typed it up originally
09:19 <@kanzure> i dunno
09:19 <@kanzure> people used to type up books manually
09:20 <@kanzure> and then they would put version numbers on it (i dunno why.. who would verify a version number?)
09:20 <@archels> ah. poor souls
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09:22 <@archels> yeah okay like spelling Franz Kafka as Franz Kalka
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09:25 <@kanzure> some of the misspellings are intentional and appear in the original book
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09:26 <@archels> interesting
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09:27 <@kanzure> i assume it was some literary attempt at pretending that information was lost and Newton is now called Newtton
09:28 < justanotheruser> Is there any public database containing full sequences of human DNA?
09:28 <@kanzure> 1000genomes
09:28 <@kanzure> that dump on s3
09:28 <@kanzure> that dump on ncbi
09:28 <@kanzure> etc
09:29 < justanotheruser> kanzure: any with medical records/physical attributes?
09:29 <@kanzure> that's "personal genome project"
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09:31 < justanotheruser> kanzure: cool thanks
09:32 < justanotheruser> I'm guessing there has been a lot of datamining done on this DB?
09:32 <@kanzure> i don't even know what you're asking
09:32 <@kanzure> "have people loaded this data and looked at it"
09:33 <@kanzure> "to a greater degree than people normally looking at data" or something?
09:51 < justanotheruser> kanzure: have people used computers to create statistical models to predict things such as likelyhood of cancer, hair color, etc.
09:51 < justanotheruser> based on a given DNA sequence
09:53 <@kanzure> uh, yes
09:53 <@kanzure> look at single nucleotide polymorphism
09:57 < justanotheruser> Hmm. Are there sequences that people know the exact purpose of then?
09:57 < justanotheruser> Or is it all just guesses based on the fact that many people with <attribute> have <DNA sequence>
09:59 <@kanzure> there's both
09:59 <@kanzure> you can physically observe the construction of a protein from a sequence of mRNA
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10:01 < justanotheruser> interesting.
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10:06 <@kanzure> various methods of freezing a ribosome and other related shit
10:17 <@ParahSailin> justanotheruser: short reads arcchive on ncbi
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12:01 <@kanzure> someone should deploy drones to quantify the number of bazaar/marketplace-transactions in developing countries
12:01 <@kanzure> you could probably monitor for whenever money is changing hands and publish data about that
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13:32 < drewbug> Could we use gene modifications to cure https://en.wikipedia.org/wiki/Cystic_fibrosis
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13:33 < drewbug> By "we", I just mean "people not involved in the medical establishment"
13:33 < pasky> "the medical establishment"?
13:37 < pasky> I think you'll need to get over the same hurdles as the medical establishment, at least per https://en.wikipedia.org/wiki/Cystic_fibrosis#Gene_therapy
13:42 <@kanzure> pasky: hah
13:42 <@kanzure> pasky: you mean we are subjected to the same reality? how inconsiderate.
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13:48 < drewbug> Sorry, I just mean, when you're not bound by rules of law.
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14:10 < pasky> drewbug: i don't think there are many laws the medical establishment is limited by that you'd want to break (specifically, if something needs to go through non-human trials first, you probably want it to go through non-human trials first too, unless you don't care about causalities during cure testing; if you have a basement full of test subjects, scratch what i just wrote and good luck)
14:15 <@kanzure> actually i think there's a lot of paperwork involved at the FDA for conducting the later stages of clinical trials
14:15 <@kanzure> unrelated to an actually useful clinical trial
14:16 <@kanzure> by paperwork i mean something else
14:16 <@kanzure> it would be worthwhile to know the specific things..
14:31 < drewbug> Thank you both.
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--- Log closed Sat Jan 25 00:00:44 2014