--- Log opened Sat Jan 25 00:00:44 2014
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01:20 < Lemminkainen> peparbut: https://www.cell.com/abstract/S0092-8674%2813%2901521-3
01:20 < Lemminkainen> paperbot: https://www.cell.com/abstract/S0092-8674%2813%2901521-3
01:20 < paperbot> http://libgen.org/scimag/get.php?doi=10.1016%2Fj.cell.2013.11.037
01:20 < Lemminkainen> kanzure that's all part of the IND
01:21 < Lemminkainen> the initial Phase 1AB tends to run 800 pages
01:21 < Lemminkainen> by the time it hits Phase IV trials the DMFs and INDs generally hit 15,000 pages
01:21 < Lemminkainen> the composition of which tends to run companies about $250K in man-hours alone
01:22 <@kanzure> what else?
01:22 < Lemminkainen> and the "can I make my cat glow" FAQ is actually a good idea
01:23 < Lemminkainen> I may record some with Dreg
01:23 < Lemminkainen> what else? quite a bit in legal fees, clinical administrators, and insurance along the way
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01:24 < Lemminkainen> along with patient care and renumeration, data processing costs, and the actual research costs of conducting biopsies and other medical tests
01:24 <@kanzure> the glowing cat stuff is just really annoying, creating a FAQ will attract more of those people
01:24 < Lemminkainen> and then they'll ask more intelligent questions
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08:42 <@kanzure> drewbug: did you say you're in sf?
08:43 < drewbug> I live in Harrisburg, PA, but I'll be in SF from Thursday to Sunday.
08:45 <@kanzure> oh well. i'm leaving tomorrow.
08:45 < drewbug> Aww. Darn.
08:45 < drewbug> Where do you normally reside?
08:46 <@kanzure> austin
08:47 < drewbug> Cool. If I'm ever in the area, I'd love to visit.
08:47 < drewbug> And if you're ever in good ole Pennsylvania, feel free to stop by for however long you'd like.
08:47 < gradstudentbot> That's not really surprising since they did it ex vivo.
08:51 <@kanzure> agreed w/ gradstudentbot on this one
08:51 < gradstudentbot> I lost my pipette.
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09:22 <@kanzure> "New Bio DIY space to be open @ Addis Ababa Ethiopia"
09:23 <@kanzure> "Hello I am Apneet Aseffa I am very much interest on DIY Bio , and want to have branch at Ethiopia. basically there are a lot of masters, PHD graduates and also importantly high school students too interested on bio tech hacking i want to create this DIYBio Space in my area, before this idea off-course we worked on DIY Artificial intelligence Robotics lab. We just want to expand more on bio hacking too"
09:26 < drewbug> Fun.
09:27 < gradstudentbot> Who the hell stole my pipette?
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09:31 < FourFire> kanzure, is gradstudentbot's random science related outbursts helpful to the channel?
09:31 < gradstudentbot> Who has the latest version of the paper?
09:32 < drewbug> Morale booster.
09:34 <@kanzure> FourFire: no
09:34 <@kanzure> FourFire: but nobody has proposed banning him yet
09:35 < FourFire> ok, fair enough
09:35 <@kanzure> i am open to the idea
09:35 <@kanzure> of not having him around
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09:39 < FourFire> maybe, have the creator further diversify it's dialogue?
09:46 < chido> I like him
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10:04 < drewbug> I like him, too.
10:04 < drewbug> Or her.
10:04 < drewbug> Or it.
10:04 < chido> them.
10:05 < drewbug> Yeah, but sometimes people get mad at me for using "them" as a singular pronoun.
10:06 < gradstudentbot> Wasn't there a paper about that?
10:06 < chido> sometimes people get mad at me when I don't
10:08 < chido> gradstudentbot: stop reading gender studies
10:08 < gradstudentbot> Wow, I'm definitely not including this data in the paper.
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10:21 < FourFire> drewbug I use them sometimes
10:21 < FourFire> but a bot is clearly it
10:21 < drewbug> Why?
10:21 < FourFire> my mind-feel says so
10:21 < FourFire> no agency
10:21 < FourFire> it's not a person
10:21 < drewbug> Ships can be "her", though.
10:22 < gradstudentbot> Yeah, it should take me about 2 days.
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17:43 < justanotheruser> Hello gradstudentbot
17:43 < gradstudentbot> Why did I go to grad school?
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18:38 < Vutral> hi justanotheruser
18:38 < Vutral> ... i need dmso
18:39 < justanotheruser> Vutral: can you not order it online?
18:39 < Vutral> hm i could
18:40 < Vutral> i guess
18:40 < Vutral> i need to check if they ship it
18:40 < Vutral> there are some laws on shipping chemicals
18:40 < Vutral> which are more or less useless partially
18:40 < Vutral> liek that you cant ship F
18:44 < justanotheruser> Vutral: synthesize it from stuff you can order
18:46 < Vutral> did that before
18:46 < Vutral> but then i need to waste solvents
18:46 < Vutral> ^^
18:47 < Vutral> or consult the chemical seller of my trust
18:49 < Vutral> i think i found some kind of ""movement"" which says dmso is good for skin
18:49 < Vutral> and they sell 99,999% dmso because of it
18:49 < Vutral> lol
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19:51 < justanotheruser> Favorite podcast?
19:52 < justanotheruser> Vutral: the wiki says it is being researched to help cancer patients
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20:28 < Vutral> yeah still its toxic if pure
20:28 < Vutral> but i dont like paying for transporting water
20:28 < Vutral> +g+
20:29 < Vutral> i just wondered if capsicum plants got intresting alkaloids beside capsaicine
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20:30 < Vutral> i think if i dont find an analysis i will go over to look for its genome ^^
20:30 < Vutral> thats easier to find *g*
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20:31 < Vutral> The capsicum transcriptome DB: a "hot" tool for genomic research.
20:32 < Vutral> dx.doi.org/10.6026/97320630008043
20:33 < Vutral> all this stress of seeking some breakfast
20:34 < Vutral> i could really need a robot which can make eggs
20:39 < justanotheruser> Vutral: how much of an inconvenience would you say having chemicals shipped, or having to synthesize them yourself is? (a bit of market research)
20:42 < Vutral> well having them shipped can be stress if the seller doesnt keep records of stuff properly
20:43 < justanotheruser> Vutral: Are you a hobby chemist?
20:43 < Vutral> that doesnt matter for that
20:43 < Vutral> if he doesnt keep records you have to confirm that you received the chemicals at least
20:44 < Vutral> i can go to the university to the chemical trade they have there
20:44 < justanotheruser> Vutral: Yeah, I realize. I was just curious if you were professional.
20:45 < Vutral> well i did bioinformatics a while ^^
20:46 < Vutral> i mean i guess everyone can make dmso ^^
20:46 < Vutral> in a quick dirty and dangerous way
20:46 < Vutral> but hm ^^
20:46 < Vutral> i dont like feeling like a microbe
20:47 < justanotheruser> Vutral: Microbes make dmso?
20:48 < Vutral> no
20:48 < Vutral> but if you engineer an organism ^^
20:48 < Vutral> and you dont want some kind of marking that its a GMO
20:48 < Vutral> you use dimethylsulfate
20:48 < Vutral> ^^
20:48 < Vutral> and you can make dmso from dimethylsulfide ^^
20:48 < justanotheruser> what is ^^
20:48 < justanotheruser> a bird?
20:48 < Vutral> a bat
20:48 < Vutral> i guess
20:48 < Vutral> or 2 eyebrows
20:48 < justanotheruser> oh
20:49 < Vutral> no idea why i type it so frequent
20:49 < Vutral> but some people find it more friendly
20:49 < justanotheruser> ¯\_(ツ)_/¯
20:49 < Vutral> have you tried shooting genes in mcirobes with dimethylsulfate ?
20:50 < Vutral> i wouldnt do it with strict personal safety ^^
20:50 < Vutral> without
20:50 < Vutral> ^^
20:50 < Vutral> 10 gramm or so suffice to alkylate all dna in a human
20:50 < gradstudentbot> No, you definitely have a right to your own opinion. I just.. wish you wouldn't voice it.
20:50 < justanotheruser> Vutral: no, but I plan on picking up amateur chemistry
20:50 < Vutral> i made a channel for interdisciplinary science
20:50 < Vutral> thought there arent many people in it yet ^^
20:50 < Vutral> i hope sometime there will be *g*
20:51 < justanotheruser> what is it?
20:51 < Vutral> ##interdisciplinary
20:54 <@kanzure> https://github.com/mitsuhiko/flask-sqlalchemy/issues/60
20:54 <@kanzure> "Here's the scenario: you have some pre-existing sqlalchemy models that you are using to manage your ultra-awesome patch clamp microdialysis beowulf cluster. One day, you decide that you want a simple python web app to expose dish health/status to your meddling advisor, while he's away in Sweden at some technical conference living it up. What is a programmer to do? Maybe something like this."
20:54 <@kanzure> oh, wait that was me
20:54 <@kanzure> fuck
20:54 < gradstudentbot> Hood life: https://www.facebook.com/photo.php?fbid=296519020495014
20:55 < n_bentha> i feel like i'm lost
20:55 < n_bentha> what is the topic?
21:02 < justanotheruser> n_bentha: are you confused? "biohacking, nootropics, transhumanism, open hardware"
21:02 < Vutral> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC204052/pdf/aem00126-0050.pdf baceteria make dmso
21:02 < n_bentha> why are we discussing dmso?
21:03 < Vutral> it was on topic some minutes ago
21:03 < Vutral> ^^
21:03 < justanotheruser> n_bentha: I would consider it biohacking
21:03 < Vutral> yeah dmso is a common solvent
21:03 < justanotheruser> also, science and chemistry seem to be on topic in this channel even though it isn't explicitly stated
21:04 < justanotheruser> Vutral: are you going to replicate their experiment?
21:04 < Vutral> i worked with fungii
21:04 < Vutral> candida
21:04 < Vutral> a bit
21:04 < Vutral> ^^
21:04 < Vutral> but i need to build a new bioreactor/incubator
21:04 < Vutral> for experiments
21:05 < justanotheruser> Vutral: What is your professional field? Biology?
21:06 < Vutral> more chemistry
21:06 < gradstudentbot> Are you published?
21:07 < justanotheruser> okay cool
21:07 < n_bentha> oh ok...just thought dmso was so common that it was a waste to biohack it into a organism
21:08 < justanotheruser> Well I'm going to go. Nice talking to you. Is anyone going to the Texas Bitcoin conference?
21:08 < justanotheruser> Will check answers when I come back
21:08 < Vutral> well i got knowledge on genetics medicine chemistry and biology
21:09 < Vutral> also informatics and engineering
21:09 < Vutral> so this room is right for me
21:09 < Vutral> good luck justanotheruser
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21:21 <@ParahSailin> dmso is biogenic though
21:21 <@ParahSailin> plankton emit it, thats why we associate dmso with sea smell
21:24 < n_bentha> Vutral, use a protein scaffold for your enzymes.
21:24 < n_bentha> Will help the efficiency/productivity of the bacteria
21:25 < n_bentha> http://www.ncbi.nlm.nih.gov/pubmed/23357532
21:25 < paperbot> http://libgen.org/scimag/get.php?doi=10.1016%2Fj.copbio.2013.01.003
21:30 < Vutral> intresting
21:47 < Vutral> so i am eating cake drinking green tea and some chai tea be back in a bit
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--- Log closed Sun Jan 26 00:00:45 2014