--- Log opened Tue Apr 01 00:00:21 2014 00:12 < stieruridir> kanzure, you see the Sinclair study that came out a few months ago? I'm 95% sure it's old news to you, but worth checking 00:13 < stieruridir> mice, anti-aging, yadda yadda 00:14 -!- pietra [~hrouhan@24.60.79.55] has quit [Quit: quit] 00:22 -!- HEx1 [~HEx@hexwab.plus.com] has quit [Read error: Connection reset by peer] 00:22 -!- HEx2 [~HEx@hexwab.plus.com] has joined ##hplusroadmap 00:25 -!- HEx2 [~HEx@hexwab.plus.com] has quit [Read error: Operation timed out] 00:33 -!- _sol_ [~SolGr@c-50-166-90-49.hsd1.nj.comcast.net] has quit [Ping timeout: 245 seconds] 00:33 -!- _Sol_ [~SolGr@c-50-166-90-49.hsd1.nj.comcast.net] has joined ##hplusroadmap 01:03 -!- lichen [~lichen@c-50-139-11-6.hsd1.or.comcast.net] has joined ##hplusroadmap 01:33 -!- FourFire [~fourfire@159.171.124.1] has joined ##hplusroadmap 01:45 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 01:52 -!- QuadIngi [~fourfire@159.171.124.1] has joined ##hplusroadmap 01:53 -!- QuadIngi [~fourfire@159.171.124.1] has quit [Client Quit] 01:55 -!- kyknos [~kyknos@89.233.130.143] has quit [Ping timeout: 264 seconds] 03:21 -!- yorick [~yorick@oftn/member/yorick] has joined ##hplusroadmap 03:54 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has quit [Remote host closed the connection] 03:55 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has joined ##hplusroadmap 03:59 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has quit [Ping timeout: 252 seconds] 04:08 -!- FourFire [~fourfire@159.171.124.1] has quit [Quit: Leaving] 04:31 -!- FourFire [~fourfire@128-221-15.connect.netcom.no] has joined ##hplusroadmap 04:37 -!- xyz_ [42e7d3ea@gateway/web/freenode/ip.66.231.211.234] has joined ##hplusroadmap 04:38 -!- xyz_ [42e7d3ea@gateway/web/freenode/ip.66.231.211.234] has quit [Client Quit] 04:42 -!- yorick [~yorick@oftn/member/yorick] has quit [Remote host closed the connection] 04:42 -!- yorick [~yorick@oftn/member/yorick] has joined ##hplusroadmap 05:27 -!- Adifex is now known as Adifex|zzz 05:29 -!- nsh [~nsh@host217-43-194-68.range217-43.btcentralplus.com] has quit [Changing host] 05:29 -!- nsh [~nsh@wikipedia/nsh] has joined ##hplusroadmap 05:43 -!- HEx1 [~HEx@hexwab.plus.com] has joined ##hplusroadmap 06:19 -!- eudoxia [~eudoxia@r190-135-112-101.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 06:25 -!- Burninate [~Burn@pool-173-66-15-196.washdc.fios.verizon.net] has quit [Read error: Connection reset by peer] 06:25 -!- Burninate [~Burn@pool-173-66-15-196.washdc.fios.verizon.net] has joined ##hplusroadmap 06:26 -!- Burninate [~Burn@pool-173-66-15-196.washdc.fios.verizon.net] has quit [Read error: Connection reset by peer] 06:26 -!- Burninate [~Burn@pool-173-66-15-196.washdc.fios.verizon.net] has joined ##hplusroadmap 06:29 -!- ruthie [~ruthie@98.225.143.81] has joined ##hplusroadmap 06:30 -!- ruthie [~ruthie@98.225.143.81] has quit [Remote host closed the connection] 06:30 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has joined ##hplusroadmap 06:35 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has quit [Ping timeout: 245 seconds] 06:59 -!- Baube [~Baube@65.95.14.15] has left ##hplusroadmap [] 07:00 -!- Baube [~Baube@65.95.14.15] has joined ##hplusroadmap 07:01 -!- ThomasEgi [~thomas@185.5.8.81] has joined ##hplusroadmap 07:01 -!- ThomasEgi [~thomas@185.5.8.81] has quit [Changing host] 07:01 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap 07:13 -!- pietra [~hrouhan@24.60.79.55] has joined ##hplusroadmap 07:30 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has joined ##hplusroadmap 07:42 -!- FourFire [~fourfire@128-221-15.connect.netcom.no] has quit [Ping timeout: 240 seconds] 07:46 -!- EnLilaSko [EnLilaSko@unaffiliated/enlilasko] has joined ##hplusroadmap 07:58 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 08:19 -!- eridu [~eridu@gateway/tor-sasl/eridu] has joined ##hplusroadmap 08:33 -!- pietra [~hrouhan@24.60.79.55] has quit [Ping timeout: 245 seconds] 08:38 -!- nmz787_i [nmccorkx@nat/intel/x-aqhealmiqcnfagjq] has joined ##hplusroadmap 09:48 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 252 seconds] 09:55 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 10:11 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has quit [Remote host closed the connection] 10:12 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has joined ##hplusroadmap 10:16 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has quit [Ping timeout: 252 seconds] 10:19 < kanzure> you can't yadda yadda mice 10:19 -!- goltho [~hrouhan@24.60.79.55] has joined ##hplusroadmap 10:23 -!- eridu [~eridu@gateway/tor-sasl/eridu] has quit [Quit: Leaving] 10:24 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has joined ##hplusroadmap 10:45 -!- AshleyWaffle [~waffle@gateway/tor-sasl/anastasiawyatt] has joined ##hplusroadmap 10:46 -!- goltho [~hrouhan@24.60.79.55] has quit [Quit: quit] 11:17 -!- eudoxia [~eudoxia@r190-135-112-101.dialup.adsl.anteldata.net.uy] has quit [Quit: leaving] 11:22 < kanzure> stieruridir: nope didn't see it 11:29 -!- drewbot_ [~cinch@ec2-50-17-51-53.compute-1.amazonaws.com] has quit [Remote host closed the connection] 11:29 -!- drewbot [~cinch@ec2-54-82-86-243.compute-1.amazonaws.com] has joined ##hplusroadmap 11:30 -!- AshleyWaffle_ [~waffle@gateway/tor-sasl/anastasiawyatt] has joined ##hplusroadmap 11:31 -!- AshleyWaffle [~waffle@gateway/tor-sasl/anastasiawyatt] has quit [Ping timeout: 265 seconds] 11:37 -!- upgrayeddd [uid2969@gateway/web/irccloud.com/x-wpluqqldruwmumgo] has joined ##hplusroadmap 12:02 -!- AshleyWaffle_ [~waffle@gateway/tor-sasl/anastasiawyatt] has quit [Remote host closed the connection] 12:02 -!- AshleyWaffle [~waffle@gateway/tor-sasl/anastasiawyatt] has joined ##hplusroadmap 12:22 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 12:26 < kanzure> paperbot: http://dl.acm.org/citation.cfm?id=806707 12:26 < paperbot> ConnectionError: [Errno 111] Connection refused (file "/usr/local/lib/python2.7/dist-packages/requests/models.py", line 625, in send) 12:26 < kanzure> paperbot: http://dl.acm.org/citation.cfm?id=806707 12:26 < paperbot> ConnectionError: [Errno 111] Connection refused (file "/usr/local/lib/python2.7/dist-packages/requests/models.py", line 625, in send) 12:26 < kanzure> impressive 12:37 -!- entelechios [~elysium@181.194.151.226] has quit [Read error: Operation timed out] 12:39 -!- goltho [~hrouhan@24.60.79.55] has joined ##hplusroadmap 12:45 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has quit [Remote host closed the connection] 12:46 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has joined ##hplusroadmap 12:50 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has quit [Ping timeout: 240 seconds] 13:14 -!- Viper168_ [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 13:15 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 240 seconds] 13:20 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has joined ##hplusroadmap 13:25 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has quit [Ping timeout: 246 seconds] 13:26 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has joined ##hplusroadmap 13:27 -!- trotsky [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has joined ##hplusroadmap 13:30 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has quit [Ping timeout: 240 seconds] 14:04 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 14:05 -!- Viper168_ [~Viper@unaffiliated/viper168] has quit [Ping timeout: 252 seconds] 14:18 -!- giantabc [40c9f6c6@gateway/web/freenode/ip.64.201.246.198] has joined ##hplusroadmap 14:18 < giantabc> paperbot: http://www.sciencedirect.com/science/article/pii/S0092867414002803 14:18 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/629577148d6e23c163fb276b38eb006a.txt 14:19 < kanzure> better luck next time 14:19 < kanzure> also hi 14:19 < giantabc> let's try again :) 14:19 < giantabc> paperbot: http://www.cell.com/abstract/S0092-8674(14)00280-3 14:19 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/Integrating%20Biological%20Redesign%3A%20Where%20Synthetic%20Biology%20Came%20From%20and%20Where%20It%20Needs%20to%20Go.pdf 14:21 -!- giantabc [40c9f6c6@gateway/web/freenode/ip.64.201.246.198] has quit [Client Quit] 14:21 < kanzure> how rude 14:24 < kanzure> proposal to make bitcoin a finite money supply https://gist.github.com/sipa/9920696 14:24 < kanzure> "This style relies less heavily on clever C++ and is more familiar to the Core Dev Team who are primarily PHP programmers." 14:29 < jrayhawk_> paperbot: http://www.sciencemag.org/content/325/5937/201.full.pdf 14:29 < paperbot> XMLSyntaxError: None (file "/home/bryan/code/paperbot/phenny/modules/scihub.py", line 51, in _go) 14:30 < jrayhawk_> exciting 14:30 < kanzure> congratulations you found a new problem 14:31 < kanzure> paperbot: http://www.sciencemag.org/content/325/5937/201 14:31 < paperbot> ConnectionError: [Errno 111] Connection refused (file "/usr/local/lib/python2.7/dist-packages/requests/models.py", line 625, in send) 14:31 < kanzure> wtf? 14:31 < kanzure> my ultimate goal is to be banned by every major science institution in the world 14:32 < kanzure> for reading too much 14:54 -!- AshleyWaffle [~waffle@gateway/tor-sasl/anastasiawyatt] has quit [Ping timeout: 265 seconds] 14:55 -!- upgrayeddd [uid2969@gateway/web/irccloud.com/x-wpluqqldruwmumgo] has quit [Quit: Connection closed for inactivity] 15:04 -!- trotsky [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has quit [Remote host closed the connection] 15:04 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has joined ##hplusroadmap 15:10 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has quit [Ping timeout: 252 seconds] 15:10 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has joined ##hplusroadmap 15:27 -!- kuldeepdhaka [~kuldeepdh@unaffiliated/kuldeepdhaka] has quit [Ping timeout: 246 seconds] 15:31 -!- EnLilaSko [EnLilaSko@unaffiliated/enlilasko] has quit [Remote host closed the connection] 15:41 < stieruridir> kanzure: http://hms.harvard.edu/news/genetics/new-reversible-cause-aging-12-19-13 15:41 < stieruridir> from December 15:50 -!- yorick [~yorick@oftn/member/yorick] has quit [Remote host closed the connection] 15:59 -!- eudoxia [~eudoxia@r186-55-38-103.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 16:15 -!- Dapple01 [40c9f6c6@gateway/web/freenode/ip.64.201.246.198] has joined ##hplusroadmap 16:16 -!- Dapple01 [40c9f6c6@gateway/web/freenode/ip.64.201.246.198] has quit [Client Quit] 16:29 -!- AshleyWaffle [~waffle@gateway/tor-sasl/anastasiawyatt] has joined ##hplusroadmap 16:30 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has quit [Remote host closed the connection] 16:30 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has joined ##hplusroadmap 16:33 < kanzure> nick pinkston is doing another startup, 16:33 < kanzure> https://angel.co/plethora 16:33 < kanzure> "Our Mission: We're making hardware as easy as software by giving you "engineering superpowers" - tools that eliminate the complexity, guess work, and schlepping that hardware engineering currently full of. To do this, we put the brain of a manufacturing engineer inside software to give you real-time feedback and make your parts super-fast." 16:33 < kanzure> "+ Full-Auto Factory: It's like Amazon Web Services meets a Robotic Factory: you send us CAD files and we automatically manufacture your parts as fast as next day." 16:33 < kanzure> "+ CAD Plug-in (pictured above): This acts like a debugger for mechanical designs. We highlight any errors you have, show you how to reduce costs, show what the turnaround time will be, etc. Then when you're ready, press "Make" and your design is manufactured in our factory and sent directly to you." 16:33 < kanzure> "We're starting off offering CNC milling services, but we'll quickly expand into other manufacturing / finishing processes in the near future." 16:34 < kanzure> so maybe something like aws/ec2 for accessing a flexible manufacturing cell would be interesting 16:34 < kanzure> but just raw access to a remote cnc lathe is less interesting, because you can't move it or do anything else with the part 16:34 < kanzure> and, just uploading a cad file is nothing like aws 16:34 < kanzure> "+ The "Compiler": This other engine lives in our factory and essentially takes the CAD object and converts it into automation commands, tooling, etc. for our machine tools and robots to fully produce and QC the design." 16:35 < kanzure> "+ The Factory Control System is essentially a web app that deals with the commands, log data, etc. - this is what actually sends the control commands from the "compiler" to the factory." 16:35 -!- ruthie [~ruthie@dhcp-130-58-192-128.swarthmore.edu] has quit [Ping timeout: 240 seconds] 16:35 -!- wwiii [~tpi@c-107-4-148-59.hsd1.va.comcast.net] has quit [Quit: Leaving] 16:35 < kanzure> terrible site too http://www.plethora.io/ 16:37 < eudoxia> it's like a hybrid between a PSD-to-HTML service and an early version of bootstrap 16:43 < kanzure> so if you have to make your hardware parts remotely in a flex cell, does that really fix the prototyping/iteration time 16:44 < kanzure> at minimum there is going to be delivery times getting it to your door 16:44 < kanzure> i suppose that's not bad, it's only a one-way delivery time 16:44 < kanzure> if your prototype doesn't work, you just mail yourself the next one, you don't really have to mail parts back unless you want to 16:52 < nmz787_i> 123d catch seems cooler than that! 16:52 < kanzure> are you just spouting random product names 16:52 < kanzure> none of this was about 3d visualization from 2d images 16:52 < nmz787_i> no 16:52 < nmz787_i> CAD for the cloud 16:52 < nmz787_i> 123d catch is CAD 16:53 < nmz787_i> jrayhawk_: did you get that science article, i can't tell if i have access or its open-access 16:54 -!- soylentbomb [~k@65.79.1.34] has joined ##hplusroadmap 17:05 < kanzure> even with parts being mailed to you, the cycle is still too long compared to software 17:22 -!- ruthie [~ruthie@c-98-225-143-81.hsd1.pa.comcast.net] has joined ##hplusroadmap 18:05 -!- eudoxia [~eudoxia@r186-55-38-103.dialup.adsl.anteldata.net.uy] has quit [Quit: leaving] 18:27 < kanzure> lorenzo is doing a dna ligation startup 18:31 < jrayhawk_> nmz787_i: it's not open access, but it worked fine through not-paperbot 18:36 < kanzure> throwaway: "put a load balancer on every node in the cluster" would probably raise a bunch of venture capital money 18:40 < kanzure> what was the company that took bone marrow from you and then "retrained" your immune system before giving it back to you? 18:40 < kanzure> was that derya unutmaz's company? 18:48 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Remote host closed the connection] 19:10 -!- soylentbomb [~k@65.79.1.34] has quit [Quit: leaving] 19:30 -!- nmz787_i [nmccorkx@nat/intel/x-aqhealmiqcnfagjq] has quit [Quit: Leaving.] 19:35 < kanzure> oh yeah, people have been using ultrasound for plasmid uptake 19:46 -!- goltho [~hrouhan@24.60.79.55] has quit [Quit: quit] 20:00 < kanzure> http://pando.com/2012/12/13/transcriptics-wild-seed-round-the-internet-was-just-trying-to-throw-money-at-us/ 20:01 -!- wwiii [~tpi@c-107-4-148-59.hsd1.va.comcast.net] has joined ##hplusroadmap 20:23 < kanzure> can anyone find a good diagram of a flex cell, that would illustrate to others the point of it 20:23 < kanzure> all i'm seeing are just diagrams of boxes 20:24 < kanzure> aren't they supposed to have robotic arms? 20:27 < kanzure> there should be an api for scienceexchange. how do they not have one. 21:17 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 255 seconds] 21:24 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 21:39 -!- entelechios [~elysium@181.194.151.226] has joined ##hplusroadmap 21:56 -!- kyknos [~kyknos@89.233.130.143] has joined ##hplusroadmap 21:57 -!- Adifex|zzz is now known as Adifex 22:21 -!- poppingtonic [~poppingto@212.49.88.107] has joined ##hplusroadmap 22:22 < poppingtonic> paperbot: http://dx.doi.org/10.1007/978-1-61779-564-0_20 22:22 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/b2c28d5ad9cf89945568529f6090a850.txt 22:24 < poppingtonic> paperbot: http://link.springer.com/content/pdf/10.1007%2F978-1-61779-564-0_20.pdf 22:24 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/550212e027642d4385200ab7cbf930ee.txt 22:26 -!- naish411 [43a90b5d@gateway/web/freenode/ip.67.169.11.93] has joined ##hplusroadmap 22:27 < naish411> paperbot: http://www.nature.com/nrm/journal/v15/n4/full/nrm3767.html 22:30 < paperbot> ConnectionError: [Errno 110] Connection timed out (file "/usr/local/lib/python2.7/dist-packages/requests/models.py", line 625, in send) 22:31 < kanzure> you guys are not having good luck with paperbot today 22:31 < kanzure> i suggest bugfixing 22:31 < naish411> <- newbie... how does one do that? 22:32 < kanzure> https://github.com/kanzure/paperbot 22:32 < kanzure> the old fashion way... with code. and programming. 22:33 < kanzure> and maybe a pizza 22:36 < naish411> see if this one works 22:36 < naish411> paperbot: http://dx.doi.org/10.1038/nrm3767 22:36 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/fe78eb15dba3ca2c3088b458cf9726e3.txt 22:39 < naish411> paperbot: http://www.nature.com/nrm/journal/vaop/ncurrent/full/nrm3767.html 22:39 < kanzure> yeah i think it's having some problems. 22:40 < kanzure> sorry, but you'll just have to file a bug report and wait until i fix whatever the underlying bug is 22:40 < kanzure> which is non-obvious to me at the moment 22:40 < naish411> not a problem. Thanks for having a look. I'll check out the github repo myself 22:41 < kanzure> 22:40 ConnectionError: [Errno 110] Connection timed out (file "/usr/local/lib/python2.7/dist-packages/requests/models.py", line 625, in send) 22:41 < kanzure> probably blocked 22:42 < paperbot> ConnectionError: [Errno 110] Connection timed out (file "/usr/local/lib/python2.7/dist-packages/requests/models.py", line 625, in send) 22:46 < naish411> one last try 22:46 < naish411> paperbot: http://www.nature.com/nrm/journal/v15/n4/pdf/nrm3767.pdf?WT.ec_id=NRM-201404 22:46 < kanzure> you are very desperate to read about terrible synthetic biology opinions 22:46 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/fcf7c44acfcb74a5f12a0cd17f34f296.pdf 22:46 < kanzure> wat how did that work 22:47 < naish411> it became less about the article and more about seeing what was happening with paperbot 22:48 < kanzure> "why everyone should be a sleepless synthetic biologist, signed by dr. sleepless himself" 22:49 < kanzure> "the authors would like to note that george church owns basically a tiny portion of literally every conceivable company that you will ever encounter in this industry" 22:49 * kanzure taps the channel topic 22:51 < kanzure> "due to the massive amount of ink that it would cost to print out his entire list of conflicts of interest, he has decided to forego the remainder of his career and retire in a puff of smoke" 22:52 < kanzure> which of course isn't very unusual for these biologist types. they escape easily, like the octopus.. 23:00 < naish411> don't know why that worked. 23:03 -!- naish411 [43a90b5d@gateway/web/freenode/ip.67.169.11.93] has quit [Quit: Page closed] 23:23 -!- Baube [~Baube@65.95.14.15] has quit [Ping timeout: 240 seconds] --- Log closed Wed Apr 02 00:00:23 2014