--- Log opened Sat Jul 12 00:00:01 2014
00:22 < ebowden_> paperbot: http://informahealthcare.com/doi/pdf/10.3109/00207454.2011.558225
00:22 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/2207cd66b3974d7def59792ca1fa02f3.txt
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00:23 < ebowden_> :(
00:23 < ebowden_> paperbot: http://informahealthcare.com/doi/abs/10.3109/00207454.2011.558225
00:23 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/ffac3725b7c1233908f8b7d261e8513c.txt
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08:01 < kanzure> hm
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08:18 < kanzure> http://www.techtimes.com/articles/10272/20140711/senators-ask-gilead-sciences-to-explain-itself-high-cost-of-hep-c-drug.htm
08:19 < kanzure> ParahSailin: it's too bad that these companies are on their game re: coverups and settlements for people that die without access to their drugs. otherwise a blackmarket alternative could easily kick up some media storm.
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10:21 < streety> It's interesting that the price is almost exactly the number of people expected to be cured of hepatitis C during the coming year due to this drug
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10:51 < ParahSailin> kanzure: you think there is a coverup conspiracy?
10:53 < kanzure> not a conspiracy, but they are obviously settling with patients' families that die due to non-treatment
10:53 < kanzure> isn't it just a little suspicious that there's never anything in the news about it
10:55 < kanzure> stuff like http://www.dailymail.co.uk/health/article-544112/Lung-patients-condemned-death-NHS-withdraws-expensive-drugs.html
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11:03 < ParahSailin> kanzure: not saying you're wrong, but absence of evidence...
11:04 < ParahSailin> you probably hear more of it in countries with monopsony medicine
11:04 < ParahSailin> that might actually be the market
11:04 < kanzure> ah, like http://www.petertatchell.net/aids/drugprofits.htm
11:05 < kanzure> it's actually a little peculiar
11:06 < kanzure> if people are complaining the drugs are too expensive, why aren't there lots of articles about "my son timmy died because i couldn't pay $30,000/month"?
11:06 < kanzure> i suppose nobody wants to admit it was their own lack of money that killed their kid
11:08 < kanzure> ooh http://www.mamamia.com.au/news/bianca-scott-soliris/
11:09 < kanzure> "We have created a petition to lobby the government to fund this drug as part of the Australia’s Life Saving Drugs Program. This is a program that funds expensive drugs  for people with extremely rare illnesses."
11:09 < kanzure> ok great, so while they are busy reviewing the petition, death
11:11 < kanzure> http://www.gofundme.com/biancas-battle
11:11 < streety> I'm not sure I follow your line of reasoning . . . if I'm a house builder or a landlord and a homeless person dies on the street, am I liable for their death?
11:11 < kanzure> huh?
11:12 < kanzure> no, i'm using their death as a marketing ploy
11:12 < kanzure> for cheap pirate drugs
11:12 < streety> ah right, in that context your comments make more sense
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11:39 < archels> kanzure: with this much money involved, one does begin to wonder why there isn't a larger dark market for these
11:39 < archels> or perhaps there is, and the internet just hasn't discovered it yet?
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11:51 < kanzure> well the total number of under-served patients globally is probably low per each drug
11:51 < kanzure> but probably enough for a single small operation to make money on it
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11:53 < archels> so there have to be organisations that provide these services
11:53 < archels> in a clandestine manner
11:54 < kanzure> why?
12:02 < kanzure> you mean there should be, or there already are?
12:12 < archels> it depends on the ease with which these drugs can be reproduced
12:12 < archels> for example, "Eculizumab (INN and USAN; trade name Soliris) is a humanized monoclonal antibody that is a first-in-class terminal complement inhibitor"
12:12 < archels> how straightforward is it to create these monoclonal antibodies?
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12:18 < kanzure> a monoclonal antibody? well it's not $100k worth of work
12:19 < kanzure> if you were to go get some grad students to write up a bid, it'd come in under $100k
12:19 < cluckj> get gradstudentbot on it
12:22 < archels> http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2189015/summary.html#Details
12:22 < kanzure> .title
12:22 < yoleaux> 2189015
12:23 < archels> it's the Canadian patent database
12:27 < archels> hm same thing https://www.google.nl/patents/US6355245
12:33 < kanzure> not surprising
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13:43 < streety> For a single course it might come to $100k due to setup costs (equipment etc). The variable costs would be much lower
13:44 < kanzure> entirely possible.
13:45 < kanzure> also i'm sure you can always find ways to increase costs, like purchasing overpriced equipment.
13:46 < streety> indeed
13:46 < streety> there is a minimal set of checks needed before injecting something though
13:46 < streety> although that is going to be variable depending on desperation
13:51 < kanzure> animals
13:55 < streety> what about them?
14:02 < kanzure> "set of checks".
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14:17 < streety> That wasn't actually what I was thinking about. If you're trying to copy an existing therapeutic I would aim to establish that what you have is what you were trying to copy. I don't think you need to show that it works and/or is non-toxic in an animal
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--- Log closed Sun Jul 13 00:00:02 2014