--- Log opened Fri Sep 04 00:00:00 2015 00:03 -!- strangewarp [~strangewa@50.141.113.47] has quit [Ping timeout: 272 seconds] 00:26 -!- jenelizabeth [~jenelizab@cpc76794-brmb10-2-0-cust21.1-3.cable.virginm.net] has quit [Remote host closed the connection] 00:27 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 00:28 -!- strangewarp [~strangewa@50.141.115.85] has joined ##hplusroadmap 01:01 -!- james4trek [~administr@c-98-195-205-7.hsd1.tx.comcast.net] has joined ##hplusroadmap 01:02 < james4trek> Hello all. Hope to chat friendly-like with nanotechnologists and anyone who still talks about NanoEngineer. I read a log and found only stuff from 2012. Am I missing something, or has this channel moved onto another project? 01:04 < james4trek> hm, I guess everyone might be asleep? 01:04 < james4trek> I might have some free time now, so I was thinking about trying to help out. 01:05 < james4trek> Anybody? Test, one two, three. 01:06 < james4trek> Hm. Well, ... map props to Kanzure, whose exploits I read of this channel's log. :) I'm currently trying to get a chroot working for NanoEngineer. Maybe it's time for me to go to bed too. "Everyone else is doing it!" ... heh 01:08 < justanotheruser> this channel doesn't talk about nanoengineer much 01:08 < justanotheruser> I'm not sure this channel was ever dedicated to NE-1 either 01:08 < james4trek> *sigh* ... Well, hopefully I can try a few things, and maybe get a pointer or too. Sadly, I think I'm about to succumb to the spectre of sleep. 01:08 < justanotheruser> there's an occasional discussion though 01:08 < james4trek> cool, cool 01:09 < james4trek> thanks for the comment, JAU 01:09 < justanotheruser> I too came here for NE-1, but kanzure likes to pretend he recruited me from #bitcoin 01:10 < james4trek> heh 01:10 < james4trek> I see. Maybe he wants to forget it. ;- ( I've been the "last" guy who knows something before. It sucks, even if it's a nice thing you know. 01:10 < gradstudentbot> Well, that paper was actually retracted. 01:11 < james4trek> * becomes entranced by the lights beneath the water, and follows them uh-oh ... 01:17 -!- james4trek [~administr@c-98-195-205-7.hsd1.tx.comcast.net] has quit [Ping timeout: 252 seconds] 01:17 -!- sandeep_ [~sandeep@111.235.64.135] has quit [Ping timeout: 265 seconds] 01:18 < justanotheruser> I don't think he minds discussing it though it doesn't seem to be a topic of interest of his, though he has mentioned wanting to pay some russians to refactor it 01:29 -!- seanph [~seanph@101.230.15.34] has quit [Read error: No route to host] 01:30 -!- seanph [~seanph@101.230.15.34] has joined ##hplusroadmap 01:32 -!- delinquentme [~delinquen@74.61.157.78] has joined ##hplusroadmap 02:26 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 264 seconds] 02:50 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-koewlxpybmxrwdjk] has joined ##hplusroadmap 03:19 -!- superkuh [~superkuh@unaffiliated/superkuh] has quit [Read error: Connection reset by peer] 03:21 -!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap 03:37 -!- juri_ [~juri@vpn166.sdf.org] has quit [Ping timeout: 255 seconds] 04:06 -!- seanph [~seanph@101.230.15.34] has quit [Remote host closed the connection] 04:07 -!- seanph [~seanph@101.230.15.34] has joined ##hplusroadmap 04:16 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-oeljnrshpcgdnhsb] has joined ##hplusroadmap 04:17 -!- sandeep_ [~sandeep@111.235.64.135] has joined ##hplusroadmap 04:28 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Quit: Leaving] 04:31 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 04:31 -!- sandeep_ [~sandeep@111.235.64.135] has quit [Ping timeout: 240 seconds] 04:41 -!- sandeep_ [~sandeep@111.235.64.135] has joined ##hplusroadmap 05:23 -!- sandeep_ [~sandeep@111.235.64.135] has quit [Remote host closed the connection] 05:37 < kanzure> they quit the channel sorta hard to communicate with 'em 05:46 < kanzure> mems lidar for self-driving horses http://pioneer.jp/en/news/press/2015/pdf/0901-1.pdf 05:54 -!- strangewarp_ [~strangewa@c-76-25-206-3.hsd1.co.comcast.net] has joined ##hplusroadmap 05:57 -!- strangewarp [~strangewa@50.141.115.85] has quit [Ping timeout: 256 seconds] 05:57 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/Why%20you%20are%20probably%20not%20a%20brain%20in%20a%20vat.pdf 06:00 < justanotheruser> yes, my daily dose of ##hplus philosophy 06:02 < kanzure> OP_COPY_SCRIPTSIG https://bitcointalk.org/index.php?topic=164655.msg1720098#msg1720098 06:11 < kanzure> gross, lifespan.io put an add in times square wtf 06:16 -!- jenelizabeth [~jenelizab@cpc76794-brmb10-2-0-cust21.1-3.cable.virginm.net] has joined ##hplusroadmap 06:17 -!- c0rw|zZz is now known as c0rw1n 06:55 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Quit: Namaste] 07:01 -!- seanph [~seanph@101.230.15.34] has quit [Remote host closed the connection] 07:01 -!- seanph [~seanph@101.230.15.34] has joined ##hplusroadmap 07:02 -!- seanph [~seanph@101.230.15.34] has quit [Read error: Connection reset by peer] 07:05 -!- seanph [~seanph@101.230.15.34] has joined ##hplusroadmap 07:11 -!- eudoxia [~eudoxia@r167-57-55-201.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 07:31 -!- jenelizabeth [~jenelizab@cpc76794-brmb10-2-0-cust21.1-3.cable.virginm.net] has quit [Remote host closed the connection] 07:32 -!- jenelizabeth [~jenelizab@cpc76794-brmb10-2-0-cust21.1-3.cable.virginm.net] has joined ##hplusroadmap 07:39 -!- juri_ [~juri@vpn166.sdf.org] has joined ##hplusroadmap 08:52 -!- dustinm [~dustinm@105.ip-167-114-152.net] has quit [Ping timeout: 244 seconds] 08:53 -!- dustinm [~dustinm@105.ip-167-114-152.net] has joined ##hplusroadmap 08:57 < kanzure> binary visualization for reverse engineering reasons https://github.com/wapiflapi/binglide http://binvis.io/ https://www.youtube.com/watch?v=4bM3Gut1hIk 09:07 -!- sandeep [~sandeep@111.235.64.135] has joined ##hplusroadmap 09:07 -!- sandeep_ [~sandeep@111.235.64.135] has joined ##hplusroadmap 09:07 -!- sandeep [~sandeep@111.235.64.135] has quit [Read error: Connection reset by peer] 09:22 -!- fleshtheworld- [~fleshthew@2602:306:cf0f:4c20:cb:f721:c57a:5c10] has quit [Read error: Connection reset by peer] 09:22 -!- nmz787_w [8686894b@gateway/web/freenode/ip.134.134.137.75] has joined ##hplusroadmap 09:28 -!- sheena [~home@S0106c8be196316d1.ok.shawcable.net] has joined ##hplusroadmap 10:13 -!- james4trek [~administr@c-98-195-205-7.hsd1.tx.comcast.net] has joined ##hplusroadmap 10:14 < nmz787_w> is github on internet archive? 10:14 < nmz787_w> or is there some github mirror-scraper? 10:14 < nmz787_w> I was just looking at this repo a few days ago and now its gone... but I failed to clone it :/ https://github.com/dstegelman/lightweight-django-scrum 10:16 < nmz787_w> oh, I guess I found some similar repos since it was based on a book example 10:16 < kanzure> http://webcache.googleusercontent.com/search?q=cache:dbKDkfCiM1AJ:https://github.com/dstegelman/lightweight-django-scrum/commits/master+&cd=2&hl=en&ct=clnk&gl=us 10:17 -!- seanph [~seanph@101.230.15.34] has quit [Remote host closed the connection] 10:17 < kanzure> probably from https://github.com/lightweightdjango/examples 10:18 < kanzure> or https://github.com/whatsupdan/lightweight-django/tree/master/scrum-repo/scrum 10:18 < nmz787_w> yeah 10:18 < nmz787_w> I chose https://github.com/djangopractice/scrum 10:33 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 246 seconds] 10:36 -!- c0rw1n [~c0rw1n@228.208-241-81.adsl-dyn.isp.belgacom.be] has quit [Read error: Connection reset by peer] 10:37 -!- c0rw1n [~c0rw1n@228.208-241-81.adsl-dyn.isp.belgacom.be] has joined ##hplusroadmap 10:42 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 10:45 -!- c0rw1n is now known as greenbat 10:59 -!- greenbat is now known as c0rw1n 11:04 < james4trek> Show of hands, who's a bot? 11:13 < kanzure> false question, bots don't have hands 11:16 < nmz787_w> they can have 'handlers' 11:16 < nmz787_w> or 'handles' 11:20 -!- nmz787_w [8686894b@gateway/web/freenode/ip.134.134.137.75] has quit [Ping timeout: 246 seconds] 11:28 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 11:31 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:5461:5141:b45c:69bb] has joined ##hplusroadmap 11:34 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 11:35 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 11:43 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 11:44 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 11:46 -!- c0rw1n [~c0rw1n@228.208-241-81.adsl-dyn.isp.belgacom.be] has quit [Ping timeout: 244 seconds] 11:46 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 11:47 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 11:51 -!- c0rw1n [~c0rw1n@228.208-241-81.adsl-dyn.isp.belgacom.be] has joined ##hplusroadmap 11:57 < delinquentme> i have a coffee grind balloon omnigripper nmz787 11:58 < delinquentme> i shove it into things then suck 11:58 < delinquentme> on a call w the CSO from oxford biotherapeutics 11:58 < delinquentme> let me know if anyone has specific questawns 11:59 < gradstudentbot> I haven't written the abstract. 12:03 < kanzure> delinquentme: ask them if they work with any CROs (if they contract out any of their services) and if so which services or how they handle that 12:03 -!- erasmus [~esb@unaffiliated/erasmus] has joined ##hplusroadmap 12:03 < kanzure> delinquentme: also ask them if they know joseph jackson at biotechnbeyond in carlsbad 12:28 -!- eudoxia_ [~eudoxia@r167-57-96-88.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 12:30 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-koewlxpybmxrwdjk] has quit [Quit: Connection closed for inactivity] 12:30 -!- eudoxia_ [~eudoxia@r167-57-96-88.dialup.adsl.anteldata.net.uy] has quit [Client Quit] 12:31 -!- eudoxia [~eudoxia@r167-57-55-201.dialup.adsl.anteldata.net.uy] has quit [Ping timeout: 240 seconds] 12:37 < kanzure> http://www.strengthandconditioningresearch.com/hypertrophy/ 12:42 < delinquentme> sorry didnt ask 12:42 < delinquentme> wasnt interesting question for him 12:42 < delinquentme> also https://hackaday.io/post/2978 12:42 < delinquentme> for pee 12:43 -!- eudoxia [~eudoxia@167.57.96.88] has joined ##hplusroadmap 12:44 < gradstudentbot> Can I borrow some sulphuric acid? 12:44 < delinquentme> kanzure, trying to get consistent hypertrophy sucks. Had back day yesterday and im barely sore 12:44 < kanzure> delinquentme: roids, man, roids. 12:44 < delinquentme> 40 pullups and 200x reps of 190 12:45 < delinquentme> cooling glove also possible ... I've been meaning to run self-tests on water across my arms / legs / head though 12:45 < delinquentme> i dont have persistent butthole thermometer 12:45 < kanzure> such is life 12:45 < delinquentme> you're aware of the cooling glove claims right kanzure ? that dropping core body temp was, in stanford words: "comparable to effects of steroids " 12:46 < kanzure> no did not see 12:50 < CaptHindsight> http://www.dtic.mil/dtic/tr/fulltext/u2/a004776.pdf Evaluation of a Water-Cooled Helmet Liner 12:56 -!- juul [~juul@juul.io] has quit [Quit: WeeChat 0.4.2] 12:56 < kanzure> gradstudentbot: https://xkcd.com/451/ 12:56 < gradstudentbot> My pub of choice is pubmed. 12:58 < delinquentme> gradstudentbot, I like yew 12:58 < gradstudentbot> Blah, why won't they just kick me out. 12:59 < delinquentme> kanzure, thats awesome. 13:00 < CaptHindsight> only 4 minutes for Sociology? 13:01 < kanzure> engineering would be like a few seconds at most.. maybe a few milliseconds. they just know. they can sense it. 13:06 -!- juul [~juul@juul.io] has joined ##hplusroadmap 13:09 -!- hehelleshin [~talinck@66-161-138-110.ubr1.dyn.lebanon-oh.fuse.net] has joined ##hplusroadmap 13:12 -!- marchtemp [~bitnami@ec2-54-69-125-142.us-west-2.compute.amazonaws.com] has quit [Ping timeout: 244 seconds] 13:12 -!- JayDugger1 [~jwdugger@108.19.186.58] has quit [Ping timeout: 244 seconds] 13:12 -!- helleshin [~talinck@66-161-138-110.ubr1.dyn.lebanon-oh.fuse.net] has quit [Ping timeout: 244 seconds] 13:12 -!- Bakkot [~Bakkot@prime-mover.stanford.edu] has quit [Ping timeout: 244 seconds] 13:12 -!- bkero [~bkero@osuosl/staff/bkero] has quit [Ping timeout: 244 seconds] 13:12 -!- marchtemp [~bitnami@ec2-54-69-125-142.us-west-2.compute.amazonaws.com] has joined ##hplusroadmap 13:13 -!- Bakkot [~Bakkot@prime-mover.stanford.edu] has joined ##hplusroadmap 13:13 -!- bkero [~bkero@216.151.13.66] has joined ##hplusroadmap 13:13 -!- JayDugger [~jwdugger@108.19.186.58] has joined ##hplusroadmap 13:28 -!- augur [~augur@c-73-46-94-9.hsd1.fl.comcast.net] has quit [Ping timeout: 244 seconds] 13:33 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Read error: Connection reset by peer] 13:40 -!- erasmus [~esb@unaffiliated/erasmus] has joined ##hplusroadmap 13:47 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 13:58 < nsh> -- 13:58 < nsh> Many attempts have been made to understand the origin of life and biological complexity both at the experimental and theoretical levels but neither is fully explained. In an influential work, Maynard Smith and Szathmáry (1995) argued that the majority of the increase in complexity is not gradual, but it is associated with a few so-called major transitions along the way of the evolution of life. For each major transition, they identified specific mechanism 13:58 < nsh> s that could account for the change in complexity related to information transmission across generations. In this work, I propose that the sudden and unexpected improvement in the functionality of an organism that followed a major transition was enabled by a phase transition in the network structure associated with that function. The increase in complexity following a major transition is therefore directly linked to the emergence of a novel structure–fun 13:58 < nsh> ction relation which altered the course of evolution. As a consequence, emergent phenomena arising from these network phase transitions can serve as a common organizing principle for understanding the major transitions. As specific examples, I analyze the emergence of life, the emergence of the genetic apparatus, the rise of the eukaryotic cells, the evolution of movement and mechanosensitivity, and the emergence of consciousness. Finally, I discuss the im 13:58 < nsh> plications of network associated phase transitions to issues that bear relevance to the history, the immediate present and perhaps the future, of life. 13:58 < nsh> -- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322530/ 14:00 < delinquentme> kanzure, 14:00 < delinquentme> do you advertise as a hard tech consultant ? 14:00 < delinquentme> you should. 14:01 < kanzure> "technology consultant wizard dude" 14:01 < kanzure> close enough? 14:01 < kanzure> i can mock up some force lightning if that will help 14:02 < kanzure> nsh: yes yes, there's various stu kauffman stuff about punctuated equilibrium in complex dissipative systems 14:02 < nsh> right 14:05 -!- juul [~juul@juul.io] has quit [Ping timeout: 264 seconds] 14:08 -!- souljack [souljack@shell.xshellz.com] has quit [Ping timeout: 250 seconds] 14:08 -!- bkero [~bkero@216.151.13.66] has quit [Ping timeout: 264 seconds] 14:09 < delinquentme> someone made an interesting statement in comparing the stability of biological systems to those of typical chemical systems at very low temps 14:09 < delinquentme> was an interesting observation 14:09 < delinquentme> esp considering the stability / difference of complexity 14:10 -!- augur [~augur@c-73-46-94-9.hsd1.fl.comcast.net] has joined ##hplusroadmap 14:15 < delinquentme> kanzure, who in here could get me bulk pricing on FBS ? 14:18 < kanzure> fbwho? 14:19 -!- souljack [souljack@shell.xshellz.com] has joined ##hplusroadmap 14:19 -!- juul [~juul@juul.io] has joined ##hplusroadmap 14:21 < delinquentme> fecal bovine serum 14:21 < delinquentme> lulz no fetal bovine serum 14:22 < delinquentme> used for growth factors in human cell line rearing to get them to gogogogogogogrowth 14:24 -!- bkero [~bkero@216.151.13.66] has joined ##hplusroadmap 14:24 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 14:25 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 14:26 < drethelin> often used in 10 percent amounts 14:26 < drethelin> delinquentme: why are you shopping in here 14:27 < drethelin> for a standard laboratory product 14:27 < drethelin> you know who could probably get you bulk prices? a bulk distributor like fisher 14:27 < drethelin> http://www.omegascientific.com/ top hit on google for bulk fetal bovine serum 14:27 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 14:28 < kanzure> drethelin: actually, gradstudentbot resells basic reagents because we don't pay him enough 14:28 < gradstudentbot> How many papers do you have published? 14:28 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 14:29 < delinquentme> drethelin, because looking for like 1/10th the price 14:30 < delinquentme> I need to know how little I can pay to start cell line werk 14:30 < delinquentme> plz donate 14:30 < kanzure> steal some from john schloendorn isn't he down the street from you 14:31 < drethelin> just buy a cow 14:31 < drethelin> and draw your own cow blood 14:34 < drethelin> I could ask my dad if you want 14:34 < drethelin> he might know a cheap source 14:35 < drethelin> he's pretty thrifty about lab supplies 14:36 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 14:37 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 14:45 < delinquentme> drethelin, yeah if you think he might have significantly cheaper FBS 14:45 < delinquentme> absoroot rey 14:47 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 14:53 < drethelin> I dunno 14:53 < drethelin> we might just pay retail for it 14:53 < drethelin> since we don't use lot 14:55 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 14:56 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 14:57 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 14:58 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Ping timeout: 255 seconds] 15:01 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 15:02 -!- nmz787_w [8686894b@gateway/web/freenode/ip.134.134.137.75] has joined ##hplusroadmap 15:03 -!- nmz787_w is now known as nmz787_i 15:04 < delinquentme> i've picked up a new trick when recruiters try to get me on the phone: 15:04 < delinquentme> " I make it a point to not take extra phone calls until we know theres real possibility for a hire. " 15:06 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 15:09 -!- sheena [~home@S0106c8be196316d1.ok.shawcable.net] has quit [Ping timeout: 250 seconds] 15:09 < kanzure> delinquentme: "In the mean time you can talk with my assistant over the phone, but her assistant might have to schedule you for later next week. Is that OK?" 15:13 -!- eudoxia [~eudoxia@167.57.96.88] has quit [Quit: Leaving] 15:13 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 15:22 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 15:25 < delinquentme> ^^^^ 15:28 < kanzure> "We can always sign my standard agreement immediately, which offers you a flexible paid at a reasonable $3k per 8 hour reserved block." 15:33 < kanzure> https://www.kernel.org/doc/Documentation/CodingStyle 15:56 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-oeljnrshpcgdnhsb] has quit [Quit: Connection closed for inactivity] 16:01 < mgin> $3k per day? not bad 16:05 -!- math3 [uid54897@gateway/web/irccloud.com/x-qgnbigmqhzcmhcmz] has joined ##hplusroadmap 16:43 -!- erasmus [~esb@unaffiliated/erasmus] has joined ##hplusroadmap 16:45 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 246 seconds] 16:52 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 17:14 -!- poohbear is now known as StuffedwithSteak 17:15 -!- StuffedwithSteak is now known as StuffedBear 17:22 < delinquentme> drethelin, let me know if you can get cheaper than $250 / 500mL 17:22 -!- james4trek [~administr@c-98-195-205-7.hsd1.tx.comcast.net] has quit [Ping timeout: 264 seconds] 17:37 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 17:38 -!- Houshalter2 [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 17:38 -!- Houshalter2 [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 17:38 -!- Houshalter2 [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 17:54 -!- Houshalter2 [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 17:57 -!- nmz787_i [8686894b@gateway/web/freenode/ip.134.134.137.75] has quit [Ping timeout: 246 seconds] 17:57 -!- Houshalter2 [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 18:08 < kanzure> .title http://link.springer.com.sci-hub.org/article/10.1007/s10508-015-0516-2 18:08 < kanzure> 1K4t2vSBSS2xFjZ6PofYnbgZewjeqbG1TM 18:09 -!- math3 [uid54897@gateway/web/irccloud.com/x-qgnbigmqhzcmhcmz] has quit [Quit: Connection closed for inactivity] 18:18 -!- Houshalter2 is now known as Houshalter 18:20 -!- StuffedBear is now known as poohbear 18:25 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 18:29 -!- blueskin [~blueskin@2001:41d0:1:9185::1] has quit [Ping timeout: 256 seconds] 18:30 -!- blueskin [~blueskin@2001:41d0:1:9185::1] has joined ##hplusroadmap 18:39 < kanzure> .title http://www.nature.com/mp/journal/vaop/ncurrent/full/mp2015108a.html 18:39 < yoleaux> Molecular Psychiatry - A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence 18:40 < kanzure> "Although individual differences in intelligence (general cognitive ability) are highly heritable, molecular genetic analyses to date have had limited success in identifying specific loci responsible for its heritability. This study is the first to investigate exome variation in individuals of extremely high intelligence. Under the quantitative genetic model, sampling from the high extreme of the distribution should provide increased ... 18:40 < kanzure> ... power to detect associations. We therefore performed a case–control association analysis with 1409 individuals drawn from the top 0.0003 (IQ >170) of the population distribution of intelligence and 3253 unselected population-based controls. Our analysis focused on putative functional exonic variants assayed on the Illumina HumanExome BeadChip. We did not observe any individual protein-altering variants that are reproducibly ... 18:40 < kanzure> ... associated with extremely high intelligence and within the entire distribution of intelligence. Moreover, no significant associations were found for multiple rare alleles within individual genes. However, analyses using genome-wide similarity between unrelated individuals (genome-wide complex trait analysis) indicate that the genotyped functional protein-altering variation yields a heritability estimate of 17.4% (s.e. 1.7%) based on ... 18:40 < kanzure> ... a liability model. In addition, investigation of nominally significant associations revealed fewer rare alleles associated with extremely high intelligence than would be expected under the null hypothesis. This observation is consistent with the hypothesis that rare functional alleles are more frequently detrimental than beneficial to intelligence." 18:41 < kanzure> heh zip files committed to git 18:43 < kanzure> perhaps there are other aspects of cognitive ability that iq does not measure that might be more strongly genetically correlated, like working memory set size 18:44 < kanzure> .wik PLXNB2 18:44 < yoleaux> "Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene." — https://en.wikipedia.org/wiki/PLXNB2 18:44 < kanzure> "Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002)).[supplied by OMIM][3]" 18:46 < kanzure> "In addition, a specific cognitive ability missing from this study, spatial ability, should be added to the mix because spatial ability predicts occupational and creative accomplishments beyond quantitative and verbal reasoning abilities.51, 52" 18:51 -!- blackmacrame [~smuxi@199.187.248.103] has joined ##hplusroadmap 18:52 -!- blackmacrame [~smuxi@199.187.248.103] has quit [Read error: Connection reset by peer] 19:23 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 19:34 -!- hehelleshin [~talinck@66-161-138-110.ubr1.dyn.lebanon-oh.fuse.net] has quit [Ping timeout: 246 seconds] 19:41 < kanzure> .title https://www.youtube.com/watch?v=Lu9dUG3_KNA 19:41 < yoleaux> STAR WARS EP 4: Laser Moon Awakens - YouTube 19:48 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 19:53 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 19:54 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 20:13 -!- Darius [~quassel@108-203-14-66.lightspeed.irvnca.sbcglobal.net] has joined ##hplusroadmap 20:21 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:5461:5141:b45c:69bb] has quit [Disconnected by services] 20:21 -!- fleshtheworld- [~fleshthew@2602:306:cf0f:4c20:5461:5141:b45c:69bb] has joined ##hplusroadmap 20:23 -!- hehelleshin [~talinck@66-161-138-110.ubr1.dyn.lebanon-oh.fuse.net] has joined ##hplusroadmap 20:24 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-lrfwhbzwumpldbxu] has joined ##hplusroadmap 20:26 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 20:27 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 20:29 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-twubzbbeqmsdbofe] has joined ##hplusroadmap 20:49 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 20:50 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 21:07 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 21:08 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 21:13 -!- Burnin8 [~Burn@pool-96-241-89-190.washdc.fios.verizon.net] has quit [Read error: Connection reset by peer] 21:13 -!- Burnin8 [~Burn@pool-96-241-89-190.washdc.fios.verizon.net] has joined ##hplusroadmap 21:15 -!- zamanfou [~zamanfou@c-67-173-75-85.hsd1.il.comcast.net] has quit [Ping timeout: 250 seconds] 21:25 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 21:26 -!- drewbot [~cinch@ec2-54-163-171-146.compute-1.amazonaws.com] has quit [Remote host closed the connection] 21:26 -!- drewbot [~cinch@ec2-54-144-106-184.compute-1.amazonaws.com] has joined ##hplusroadmap 21:26 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 21:27 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 21:28 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has joined ##hplusroadmap 21:45 -!- Houshalter [~Houshalte@oh-71-50-57-55.dhcp.embarqhsd.net] has quit [Read error: Connection reset by peer] 21:49 -!- strangewarp_ [~strangewa@c-76-25-206-3.hsd1.co.comcast.net] has quit [Read error: Connection reset by peer] 21:49 -!- strangewarp_ [~strangewa@c-76-25-206-3.hsd1.co.comcast.net] has joined ##hplusroadmap 21:55 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 246 seconds] 21:58 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 21:59 -!- sandeep_ [~sandeep@111.235.64.135] has quit [Ping timeout: 255 seconds] 22:07 -!- Darius [~quassel@108-203-14-66.lightspeed.irvnca.sbcglobal.net] has quit [Remote host closed the connection] 22:16 -!- sheena [~home@d154-20-225-71.bchsia.telus.net] has joined ##hplusroadmap 22:19 < kanzure> hmph 22:27 -!- wrldpc1 [~ben@174.82.135.27.ap.yournet.ne.jp] has quit [Quit: wrldpc1] 22:36 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-lrfwhbzwumpldbxu] has quit [Quit: Connection closed for inactivity] 22:37 < JayDugger> Good morning, everyone. 23:31 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Ping timeout: 255 seconds] --- Log closed Sat Sep 05 00:00:01 2015