--- Log opened Sat Jun 04 00:00:20 2016
00:03 < fenn> "Adding heat energy makes it more likely that electrons will shake loose from their current states and fall down into lower states. Heating a glow in the dark toy will make it appear brighter, but the glow will fade way faster."
00:03 < fenn> that's all i know
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04:47 < kanzure> https://www.kickstarter.com/projects/608159144/the-most-mysterious-star-in-the-galaxy
04:47 < kanzure> (KIC 8462852 stuff)
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06:22 < kanzure> "Metalenses at visible wavelengths: Diffraction-limited focusing and subwavelength resolution imaging" http://science.sciencemag.org/content/352/6290/1190
06:27 < kanzure> "TumbleBit: An untrusted tumbler for bitcoin-compatible anonymous payments" http://diyhpl.us/~bryan/papers2/bitcoin/TumbleBit:%20An%20untrusted%20tumbler%20for%20bitcoin-compatible%20anonymous%20payments%20-%202016.pdf
06:45 < kanzure> "Antikernel: A decentralized secure hardware-software operating system architecture" http://eprint.iacr.org/2016/550.pdf
06:45 < kanzure> above seems to be authored by azonenberg
06:49 < kanzure> http://redmine.drawersteak.com/projects/achd-soc/repository
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09:08 < maaku> kanzure: the metalensing could potentially provide optical capabilities to in-situ MEMS devices
09:14  * kanzure checks against http://diyhpl.us/~bryan/papers2/optics/
09:17 < kanzure> http://www.seas.harvard.edu/capasso/wp-content/uploads/publications/sciencejune3-2016.pdf
09:17 < kanzure> interesting that google scholar hasn't indexed that yet.  shouldn't they re-index each of the authors if they notice a new publication?
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10:03 < fenn> http://i2.wp.com/www.deepstuff.org/wp-content/uploads/2016/06/FocusingLensGifforWeb_0.gif
10:15 < ybit> http://www.scientificamerican.com/article/tech-turns-to-biology-as-data-storage-needs-explode/
10:16 < ybit> fenn: what is that?
10:17 < ybit> i see, http://www.deepstuff.org/metalens-works-visible-spectrum-sees-smaller-wavelength-light/
10:18 < fenn> i couldn't easily access the original article so i read a pop science thing instead
10:20 < fenn> "we’re producing a lot more data than the storage industry is producing devices for" what the hell is that supposed to mean
10:39 < kanzure> "we are deleting things", probably
10:50 < nmz787_i> maaku: that paper about 'metalenses' just seem to be diffractive optics, no?
10:51 < nmz787_i> fenn: what original article? the one on sciencemag?
10:52 < kanzure> i think you mean refractive
10:53 < nmz787_i> no, i mean diffractive
10:53 < kanzure> hm
10:54 < nmz787_i> if this is just a diffractive lense, then I see the 'hard' part being software to generate the CAD model that will have the lensing effect you want
10:54 < nmz787_i> fab would be something like LIGA i guess
10:54 < nmz787_i> I am thinking that their use of TiO would make for a nice mirror like surface
10:55 < nmz787_i> so non-weird color effects added into your transformation (lensing)
10:55 < nmz787_i> i.e. I imagine TiO to be silvery like a mirror
10:57 < nmz787_i> the sciencemag article doesnt seem to show a full image of the metalense with the nanostructures in view
10:57 < nmz787_i> the supplement has one that looks like at least 50% complete: http://science.sciencemag.org/content/sci/suppl/2016/06/01/352.6290.1190.DC1/Khorasaninejad-SM.pdf
10:57 < kanzure> use http://www.seas.harvard.edu/capasso/wp-content/uploads/publications/sciencejune3-2016.pdf
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11:01 < nmz787_i> /me this 3D print has been going for almost 24 hours, with probably 8-12 more to go...
11:01 < nmz787_i> /me I chose too high-quality settings
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11:15 < nmz787_i> kanzure: nice, that paper gives the two equations it looks like, in the first page
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11:16 < nmz787_i> oh, it was TiO2, which is mirrory, not TiO
11:18 < nmz787_i> huh
11:24 < ybit> http://www.indiana.edu/~iulg/qliqc/HQL_fin.pdf
11:24 < ybit> "CATEGORICAL QUANTUM MECHANICS"
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12:16 < kanzure> .title https://groups.google.com/d/msg/diybio/FXaT-MjJQYI/l9yQbvw3BAAJ
12:16 < yoleaux> Google Groups
12:16 < kanzure> grr
12:16 < kanzure> "A hypothetical protocol for DIYBIO DNA synthesis"
12:27 < kanzure> "C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector" http://science.sciencemag.org/content/early/2016/06/01/science.aaf5573"
12:31 < kanzure> er, i mean http://science.sciencemag.org/content/early/2016/06/01/science.aaf5573
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13:02 < docl> https://azizonomics.com/2016/05/30/automation-space-colonization-the-post-transactional-economy/ .title
13:02 < docl> .title
13:02 < yoleaux> Automation, Space Colonization & The Post-Transactional Economy – azizonomics
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13:05 < kanzure> docl: disappointed with the author, he doesn't seem to propose any funding vehicles. pfft.
13:05 < kanzure> he could have, at minimum, proposed using venture capital
13:06 < docl> eder's reply, basically that's too conservative because it doesn't account for self-upgrading systems
13:06 < docl> https://www.reddit.com/r/Automate/comments/4mfxlj/automation_space_colonization_the/d3w02k0
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13:12 < docl> kanzure: well, at least he came up with some language to describe it to a vc: "essentially, a very extreme kind of full-stack real estate development"
13:13 < kanzure> aka "breaking the commodity derivatives markets"
13:13 < docl> from eder: "In reality you need more than one robot, but not more than 5 or so, and a stock of spare parts. If one robot breaks, the other robots swap parts to repair it. As long as you can keep the set running until you start producing new replacement parts, you are good to go."
13:14 < kanzure> no i'm pretty sure he has not figured out the entire set of bootstrapping components
13:14 < kanzure> afaik freitas hadn't either
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13:25 < docl> what do you think he's missing?
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13:34 < docl> .title https://medium.com/made-in-space/how-we-want-to-turn-asteroids-into-spacecraft-e95d3214d787
13:34 < yoleaux> How We Want to Turn Asteroids Into Spacecraft — Made In Space — Medium
13:37 < docl> Made In Space is getting funding to investigate something suspiciously similar to a replicator, albeit slightly less ambitious. the idea is to deliver the machinery needed to produce a giant mechanical catapult + control mechanisms from asteroid materials.
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16:00 < maaku> "The lens can resolve nanoscale features separated by distances smaller than the wavelength of light"
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17:35 < kanzure> maaku: does nasa have any open-source space navigation telemetry library things?
17:35 < kanzure> or public domain, at least. i don't care.
17:40 < maaku> This? https://naif.jpl.nasa.gov/pub/naif/toolkit_docs/C/info/intrdctn.html
17:40 < kanzure> https://github.com/nasa/europa
17:40 < kanzure> unclear whether "SPICE" (seriously nasa? what about the other SPICE) is the thing.
17:41 < kanzure> shouldn't there be something about mass, dynamics, thrust, and trajectory?
17:41 < kanzure> and orbits
17:44 < kanzure> "Evolutionary Mission Trajectory Generator " http://opensource.gsfc.nasa.gov/projects/emtg/EMTGv8.zip
17:45 < kanzure> //all data is public domain except for VASIMR and Xenon Hall thruster models which are kept in a separate sourcefile and are NOT TO BE DISTRIBUTED
17:47 < kanzure> GMAT_interface.cpp:if ((missionbodies_unique[index_body_visited].central_body_name != "Sun") && (missionbodies_unique[index_body_visited].central_body_name != "Mercury") && (missionbodies_unique
17:47 < kanzure> lolz
17:47 < kanzure> ".OrbitSpiceKernelName = {" seems that you were right
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18:04 < kanzure> "The genome project-write" http://science.sciencemag.org/content/early/2016/06/03/science.aaf6850
18:05 < kanzure> i sede church, hessel, carlson, kuiken (ugh), etc.
18:05 < kanzure> "The primary goal of HGP-write is to reduce the costs of engineering and testing large (0.1 to 100 billion base pairs) genomes in cell lines by over 1000-fold within 10 years. This will include whole-genome engineering of human cell lines and other organisms of agricultural and public health significance, or those needed to interpret human biological functions—i.e., gene regulation, genetic diseases, and evolutionary processes.
18:06 < kanzure> "This goal is necessarily ambitious, since building a human genome at today’s prices would cost more than HGP-read (9) (see fig. S1). However, an expectation of HGP-write will be to catalyze a sharp price drop as new technology development occurs apace with advancement of the project, as with the cost of DNA sequencing in HGP-read. Small viral (10) and bacterial (11) genomes synthesized from scratch and organisms with recoded genomes ...
18:06 < kanzure> ... (12) derived from large-scale genome editing (13) have demonstrated the feasibility and utility of synthetic genomes. By focusing on building the 3 Gb of human DNA, HGP-write would push current conceptual and technical limits by orders of magnitude and deliver important scientific advances."
18:06 < kanzure> "and Sc2.0 (which is synthesizing a heavily edited yeast genome) "
18:07 < kanzure> "Total Synthesis of a Functional Designer Eukaryotic Chromosome" http://science.sciencemag.org/content/344/6179/55 (2014)
18:09 < kanzure> "constructing specific chromosomes—e.g., chromosome 21"
18:10 < kanzure> $100 million budget
18:10 < kanzure> .. which is enough to cover an inkjet dna synthesizer a few times over.
18:11 < kanzure> "The train has left the station, however. HGP-write has detailed plans and an umbrella institute, the Center of Excellence for Engineering Biology, which will oversee the project. California-based software company Autodesk has committed $250,000. Next steps include organizing working groups of scientists, and raising more money. Kelley said they will look for funding from public and private sources."
18:11 < kanzure> hmm drew endy is against this. wtf.
18:11 < kanzure> "HGP-write will start by synthesizing 1 percent of the human genome and inserting those strings into human cells growing in labs, said Boeke. Its leaders are confident it will drive down the cost of synthesizing long strings of DNA into complete genomes — now 10 base pairs for $1 — by 1,000-fold within a decade, so that synthesizing a 10,000-letter-long strand of DNA will cost $1."
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18:12 < kanzure> autodesk money is obviously thanks to hessel... hrm.
18:12 < kanzure> autodesk seems like a reasonable backer for george church to pick
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18:18 < kanzure> june 8th event in NY with adam marblestone ("director of scientific architecting" in boyden's synthetic neurobiology group) https://www.media.mit.edu/events/2016/06/08/adam-marblestone-wearable-tech-digital-health-nyc-2016
18:19 < kanzure> "He will discuss the “Neurotechnology Roadmap” that he developed with Professor Ed Boyden, and previously presented at a White House BRAIN initiative conference."
18:21 < kanzure> bioviva seems to be moving to fiji
18:40 < kanzure> pmetzger is asking me why he should go to meet/hear marblestone give a talk... i thought the reasons would be obvious.
18:52 < maaku> kanzure: https://www.macfound.org/press/press-releases/new-macarthur-competition-award-100-million-help-solve-critical-social-problem/
18:52 < maaku> SENS should get on that
18:54 < maaku> kanzure: SPICE is used for translating between reference frames, which is itself a complex and interesting problem at interplanetary scales
18:54 < kanzure> someone was recently complaining that sens foundation has switched to too much of a cancer focus
18:54 < kanzure> undoubtedly the reason for focusing on cancer is probably because that's how to get grant dollars
18:54 < maaku> i don't know if there is a general library for encoding telemetry data itself, jcorgan might know
18:55 < maaku> they seem to have a whatever-the-hell-wil-get-us-money focus
18:55 < maaku> see also https://www.macfound.org/press/press-releases/new-macarthur-competition-award-100-million-help-solve-critical-social-problem/
18:55 < kanzure> samelink?
18:55 < maaku> no unrelated
18:56 < maaku> gahh
18:56 < maaku> https://www.indiegogo.com/projects/dracos-may-be-effective-against-all-viruses#/
18:56 < kanzure> yeah we have lots of stuff in the backlogs about DRACOs
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18:57 < maaku> I reference only to point out it is a SENS Research Foundation project.
18:57 < maaku> Not that related to life exentsion though...
18:57 < kanzure> iirc it was mostly venturecommunism in here who was talking about DRACOs and he has some sort of (nebulous?) connection to sens foundation maybe
18:58 < maaku> I have a low probability for macfound giving SENS that grant, but objectively they should and de Grey should get on that
18:58 < kanzure> i can't believe we lost parahsailin, bleh
18:59 < kanzure> and if NIH isn't going to fund "human genome synthesis project" then where are they going to find their $3 billion
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19:07 < maaku> parahsailin quit or just isn't around?
19:09 < kanzure> channel was ultimately not making biology progress quickly enough, so he left
19:10 < kanzure> also i think he got abducted by google
19:14 < nmz787_i> .title https://gist.github.com/nmz787/83a826ca4d40011262e7382b46c22570
19:14 < yoleaux> diffractive lens nanopillar outlines via openCV · GitHub
19:14 < nmz787_i> http://imgur.com/PKFXtCV
19:14 < nmz787_i> .title
19:14 < yoleaux> Imgur: The most awesome images on the Internet
19:17 < maaku> that is disappointing, but what can you do
19:17 < nmz787_i> now to reverse this https://gist.github.com/jblake/160932cc4cd5b6f9e5a4 and output .str files for loading into the FIB... or alternatively turn it into g-code for the bluray laser etcher (which is not yet ready here)
19:17 < nmz787_i> .title
19:17 < yoleaux> Convert FEI .str format rasters to PGM images. · GitHub
19:17 < kanzure> in pythonland i think you can use imagemagick for image drawing instead of opencv
19:18 < kanzure> or PIL things
19:19 < nmz787_i> well there's really only about 6 lines, 8 including imports, that are related to opencv... so someone else should easily be able to swap those out
19:19 < kanzure> using opencv for image editing is unfortunate because it's a rather large dependency too
19:20 < nmz787_i> meh, 19MB by my count here
19:20 < nmz787_i> for the wheel
19:20 < kanzure> :)
19:20 < nmz787_i> it runs in like a second
19:20 < nmz787_i> (not verified)
19:23 < nmz787_i> 0.11 seconds
19:23 < nmz787_i> :)
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19:27 < nmz787_i> i guess that isn't counting numpy, which ranges from 3MB to 14MB depedning on OS reqs
19:27 < kanzure> it has been a good few weeks for privacy in bitcoin land:
19:27 < kanzure> tumblebit http://diyhpl.us/~bryan/papers2/bitcoin/TumbleBit:%20An%20untrusted%20tumbler%20for%20bitcoin-compatible%20anonymous%20payments%20-%202016.pdf
19:27 < kanzure> chaumian ecash for bitcoin (before tumblebit paper) http://diyhpl.us/~bryan/papers2/bitcoin/Blindly%20signed%20contracts:%20Anonymous%20on-blockchain%20and%20off-blockchain%20bitcoin%20transactions%20-%202016.pdf
19:27 < kanzure> coinshuffle++ http://diyhpl.us/~bryan/papers2/bitcoin/P2P%20mixing%20and%20unlinkable%20p2p%20transactions%20-%20Scalable%20strong%20anonymity%20without%20external%20routers%20-%20coinshuffle++%20-%202016.pdf
19:27 < kanzure> zero knowledge contingent payments without script http://diyhpl.us/~bryan/papers2/bitcoin/Efficient%20zero%20knowledge%20contingent%20payments%20in%20cryptocurrencies%20without%20scripts%20-%202016.pdf
19:27 < kanzure> joinmarket economic analysis http://diyhpl.us/~bryan/papers2/bitcoin/Join%20me%20on%20a%20market%20for%20anonymity%20-%20joinmarket%20-%202016.pdf
19:27 < kanzure> witness encryption http://diyhpl.us/~bryan/papers2/bitcoin/Extractable%20witness%20encryption%20and%20timed-release%20encryption%20from%20bitcoin%20-%202016.pdf
19:28 < kanzure> address clustering http://diyhpl.us/~bryan/papers2/bitcoin/The%20unreasonable%20effectiveness%20of%20address%20clustering%20-%202016.pdf
19:33 < kanzure> mostly those are recent.
19:33 < kanzure> oh wrong window for that last message. ouch.
19:35 < kanzure> maaku: if someone wrote up a response to that anti-kernel paper (from today's backlog) and introduced shared memory, speculative execution, modern cache coherency and caching things, and paxos stuff, would that be something materially helpful to things you are doing, or would that be a misfire? inquiring minds want to know whether that would be timewasting.
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19:52 < kanzure> http://www.pellinglab.net/re-purposed-46/ "In Re-Purposed 46, Modulevsky and Pelling present preserved, lab-grown specimens of apples containing human cells. This work represents a ‘physical biohack’ in which apples have been re-purposed as a supporting matrix for living, artificial human tissues. The samples were created without the use of genetic engineering, instead relying on standard cell culture techniques practiced worldwide. ...
19:52 < kanzure> ... Here, Modulevsky and Pelling highlight the ability to create living, functional, biological composites that do not naturally exist in nature without resorting to the manipulation of DNA."
19:52 < kanzure> "Apple Derived Cellulose Scaffolds for 3D Mammalian Cell Culture" http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097835 (2014)
19:52 < kanzure> nmz787_i: ryan hammond in baltimore is doing a spectrometer project, perhaps you should intervene
19:53 < nmz787_i> kanzure: link/mail?
19:53 < kanzure> "Animal evolution during domestication: the domesticated fox as a model" http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763232/ (from the toronto biohacking group peer review thingy)
19:54 < kanzure> " On Saturday Amsterdam has a workshop guided by Maja Smrekar, Spela Petric, Mary Tsang, and Byron Rich on extracting and deploying your own hormones,"
19:54 < kanzure> "Oakland continues with their evolved bacterial sunscreen project, Seattle will be having a workshop where you can build a SpikerBox to monitor the action potential of neurons" hehe spikerbox is still around, that's good.
19:54 < kanzure> nmz787_i: just from steve stowell's summary.
19:56 < kanzure> juul: are there any public links about the evolved bacterial sunscreen stuff?
19:56 < nmz787_i> eh, I've found most people don't want to think about using a high-quality analog front end... they are looking for good-enough and not-UV so I guess I don't have much to say
19:57 < kanzure> well in general it seems like a good idea to not encourage people to resign themselves to mere mediocrity
19:58 < fenn> just take mediocrity and turbocharge it!
19:59 < nmz787_i> doubled the height and width of the drawing area: http://imgur.com/k7P5OQE
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20:23 < nmz787_i> adjusting parameters now to the 2mm diameter for the metalens overall... and the 0.725mm focal length
20:24 < nmz787_i> not sure if the pillars are supposed to be touching or if that is a code bug
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21:34 < maaku> kanzure: I will review the antikernel paper and get back to you on that
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22:36 < xentrac_> fenn: oh, if that heating-a-glow-in-the-dark-toy thing is correct, it definitely isn't what I saw
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--- Log closed Sun Jun 05 00:00:20 2016