--- Log opened Fri Sep 09 00:00:47 2016
--- Day changed Fri Sep 09 2016
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03:30 < abetusk> kanzure, any recommendations on ps -> gcode (open source)?
03:31 < gradstudentbot> I am sponsored by Genentech.
04:03 < abetusk> pstoedit seems to get most of the way there?
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07:25 < kanzure> dunno. maybe a brlcad tool.
07:28 < spaes> is anyone aware of any disruption in the dna sequencing library generation space?
07:28 < spaes> not necessarily diy, could be just a smaller player
07:29 < spaes> i'm interested in cheaper alternatives to the expensive kits from illumina, agilent, et al
07:31 < kanzure> that is a very specific request. you'll have to wait around for a few hours.
07:32 < kanzure> but... look at barcode generation techniques.
07:35 < spaes> k
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11:23 < nmz787_i> sup w/all you deuterostomes?
11:24 < kanzure> i wonder how much good stuff is in failed clinical trial data sets. like so what if it makes you cough up blood if it gives you perfect memory?
11:25 < gradstudentbot> I'll be at the microscope.
11:28 < nmz787_i> haha
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13:23 < FourFire> Is anyone in here presently located in Germany?
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16:53 < kanzure> https://en.wikipedia.org/wiki/Intracellular_parasite
16:53 < kanzure> intracellular parasites might be an interesting vector for novel types of surface display in vitro selection/evolution stuff. you can select for host-parasite interactions.
16:54 < kanzure> and you can maybe transfer parasites from one host to another in some circumstances
16:56 < kanzure> oh. i thought toxoplasma also did external-to-cell cysts. maybe that wasn't right. or maybe this classification is wrong.
17:04 < nmz787_i> any good ideas for STEM home schooling curriculum? K-12 but K is the thing I am immediately faced with for a single student
17:05 < kanzure> coxiella burnetii survives in aerosols (emulsions etc). that is useful. but also it's a bioweapon. so.... hrm.
17:17 < nmz787_i> is there an online song remixer?
17:17 < nmz787_i> I want to take a clip of one song/video and use it to replace the occurence of a lyric (that is repeated sometimes) in another song
17:18 < kanzure> use ffmpeg
17:19 < gradstudentbot> My project sucks.
17:21 < nmz787_i> I want to use this 'kwyjibo' https://youtu.be/o8M8GBWVXD8?t=18 word to replace "love you so" just after this https://youtu.be/rVeMiVU77wo?t=128 (and I think elsewhere)
17:22 < kanzure> use youtube-dl to grab the files. then use ffmpeg and mencode to do your video editing tasks.
17:23 < nmz787_i> actually a lot of this song could just be kwyjibo repeated
17:23 < nmz787_i> with different intonations
17:23 < nmz787_i> kanzure: well that simplistic approach would not work nicely though, my brain can synthesize internally a very nice rendering... but I cannot export :(
17:24 < kanzure> what?
17:24 < nmz787_i> i mean, ideally I'd need to remove the pre-existing lyrics, or at least some of the high freq components
17:24 < nmz787_i> then lay kwyjibo on top of the music nicely
17:25 < kanzure> use audacity for audio editing. or go pirate some actual video editing software. i'm not sure why you think mencoder can't export, but it definitely does.
17:25 < nmz787_i> no my brain can't export
17:25 < nmz787_i> I can hear exactly what I want, in my head...
17:26 < nmz787_i> I'd like to post it to youtube or facebook or whatever, to amuse others
17:27 < nmz787_i> http://stackoverflow.com/questions/14461210/matlab-removing-vocals
17:27 < nmz787_i> I wonder if that audio transcoding neural network stuff would be better at this
17:28 < nmz787_i> heh, 'now that you've found the speech accurately, subtract it'
17:28 < nmz787_i> instead of saving a transcript
17:34 < nmz787_i> http://www.yourepeat.com/watch/?v=o8M8GBWVXD8&start_at=18&end_at=18
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19:08 < kanzure> "Eye movements reveal epistemic curiosity in human observers" http://www.sciencedirect.com/science/article/pii/S0042698915003430
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19:36 < kanzure> "In contrast to this neuron-centric view of memory formation, studies of learning-related plasticity revealed that plasticity was synapse-specific, that is, it could occur at some but not all synapses made by an individual neuron [38]. This finding raised questions about how the products of gene expression, synthesized in the nucleus, could be targeted to alter structure and function at subsets of synapses within a single, highly ...
19:36 < kanzure> ... polarized and compartmentalized neuron. One solution to this question came from findings that mRNAs localized to distal dendrites and synapses [39], where their translation could be regulated by activity. These findings included detection of polyribosomes at the base of synapses as well as the identification of a subset of mRNAs that localized to distal dendrites. Studies from several labs have identified hundreds to thousands of ...
19:36 < kanzure> ... dendritically localized mRNAs [40, 41, 42] translation of which could alter the structure and function of synapses, thereby making the synapse (or neighborhood of synapses), rather than the entire neuron, the unit of plasticity."
19:37 < kanzure> from http://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0261-6
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--- Log closed Sat Sep 10 00:00:50 2016