--- Log opened Tue Nov 01 00:00:37 2016 00:32 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 265 seconds] 00:35 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 01:36 -!- hehelleshin [~talinck@66-161-138-110.ubr1.dyn.lebanon-oh.fuse.net] has joined ##hplusroadmap 01:39 -!- helleshin [~talinck@66-161-138-110.ubr1.dyn.lebanon-oh.fuse.net] has quit [Ping timeout: 260 seconds] 02:20 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-xlivihgxtbpyqdkl] has quit [Quit: Connection closed for inactivity] 02:35 < fenn> thought this part looked familiar: http://www.vander-bend.com/album_parts/#5.jpg 02:36 < fenn> let's see if anyone can guess what it is 04:09 -!- ebowden [~ebowden@CPE-101-180-233-178.lnse3.cha.bigpond.net.au] has joined ##hplusroadmap 04:09 -!- ebowden [~ebowden@CPE-101-180-233-178.lnse3.cha.bigpond.net.au] has quit [Changing host] 04:09 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 05:37 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 260 seconds] 05:53 -!- esmerelda [~andares@unaffiliated/jacco] has joined ##hplusroadmap 07:03 < kanzure> eurghh 07:10 -!- lexik [~lexik@178.248.248.165] has quit [Remote host closed the connection] 07:12 -!- lexik [~lexik@178.248.248.165] has joined ##hplusroadmap 07:22 -!- ArvinJA [~ArvinJA@web208.webfaction.com] has quit [Ping timeout: 244 seconds] 07:23 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 07:27 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 07:34 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-222-194.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 07:51 < JayDugger1> Out of coffee, or just sleep poorly? 08:01 < kanzure> out of patience for the human condition 08:03 < JayDugger1> Well, you're in the right place for that. What lies next on the roadmap? 08:05 < kanzure> total destruction of the planet 08:06 < JayDugger1> Should've been turned into computronium a long time ago. 08:06 -!- nmz787_i [ntmccork@nat/intel/x-lcpnadfucsqenall] has joined ##hplusroadmap 08:06 < JayDugger1> Silly lazy dinosaurs wasted their age, took a big whack, and their descendants turned into tasty chickens. 08:08 < TMA> JayDugger1: the universe _is_ made of computronium just now. 08:09 < TMA> JayDugger1: oh, you mean _digital_ computronium 08:10 -!- M4l3z [~M4l3z@LFbn-1-4220-37.w92-169.abo.wanadoo.fr] has joined ##hplusroadmap 08:15 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 08:20 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds] 08:37 -!- Orpheon [~Orpheon@213.200.193.129] has quit [Ping timeout: 245 seconds] 08:44 -!- c0rw1n [~c0rw1n@109.128.248.206] has quit [Ping timeout: 256 seconds] 08:52 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 250 seconds] 08:52 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 09:30 -!- nmz787_i [ntmccork@nat/intel/x-lcpnadfucsqenall] has quit [Quit: Leaving.] 09:30 -!- q4 [~textual@user-94-254-167-44.play-internet.pl] has joined ##hplusroadmap 09:33 -!- andares [~andares@2607:fb90:fe5:87f0:6c12:508:11db:b014] has joined ##hplusroadmap 09:33 -!- andares [~andares@2607:fb90:fe5:87f0:6c12:508:11db:b014] has quit [Changing host] 09:33 -!- andares [~andares@unaffiliated/jacco] has joined ##hplusroadmap 09:36 -!- esmerelda [~andares@unaffiliated/jacco] has quit [Ping timeout: 245 seconds] 09:41 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-xsdrjjrnqvwbqkmt] has joined ##hplusroadmap 10:34 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 245 seconds] 10:37 -!- nmz787_i [ntmccork@nat/intel/x-oxjauhgkuczfmrzh] has joined ##hplusroadmap 10:54 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 10:59 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds] 11:09 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 11:27 -!- lexik [~lexik@178.248.248.165] has quit [Remote host closed the connection] 11:28 -!- q4 [~textual@user-94-254-167-44.play-internet.pl] has quit [Quit: Textual IRC Client: www.textualapp.com] 11:29 -!- lexik [~lexik@178.248.248.165] has joined ##hplusroadmap 11:39 < kanzure> weird to see brian behlendorf at foresight institute things. 11:44 -!- dpk [~dpk@xn--ht-1ia18f.nonceword.org] has left ##hplusroadmap ["."] 12:10 -!- Orpheon [~Orpheon@213.200.193.129] has joined ##hplusroadmap 12:10 -!- nmz787_i [ntmccork@nat/intel/x-oxjauhgkuczfmrzh] has quit [Quit: Leaving.] 12:15 -!- q4 [~textual@user-94-254-167-44.play-internet.pl] has joined ##hplusroadmap 12:21 -!- andares [~andares@unaffiliated/jacco] has quit [Ping timeout: 260 seconds] 12:36 -!- Orpheon [~Orpheon@213.200.193.129] has quit [Read error: Connection reset by peer] 12:40 -!- Orpheon [~Orpheon@213.200.193.129] has joined ##hplusroadmap 12:51 -!- ebowden [~ebowden@2001:8003:1163:5800:740a:9ad6:dd89:5e1d] has joined ##hplusroadmap 12:51 -!- ebowden [~ebowden@2001:8003:1163:5800:740a:9ad6:dd89:5e1d] has quit [Changing host] 12:51 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 12:57 -!- crCr62U0 [~crCr62U0@mm-42-130-84-93.dynamic.pppoe.mgts.by] has joined ##hplusroadmap 12:59 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 13:00 -!- ebowden [~ebowden@2001:8003:1163:5800:f45b:932c:b375:8bcb] has joined ##hplusroadmap 13:00 -!- ebowden [~ebowden@2001:8003:1163:5800:f45b:932c:b375:8bcb] has quit [Changing host] 13:00 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 13:05 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 13:07 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 13:13 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 13:16 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 13:17 -!- nmz787_i [~ntmccork@134.134.139.70] has joined ##hplusroadmap 13:21 -!- crCr62U0 [~crCr62U0@mm-42-130-84-93.dynamic.pppoe.mgts.by] has quit [Quit: Leaving] 13:22 < jrayhawk_> .title https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692355/ 13:22 < yoleaux> Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum 13:25 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-222-194.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 268 seconds] 13:40 -!- ebowden [~ebowden@CPE-101-180-233-178.lnse3.cha.bigpond.net.au] has joined ##hplusroadmap 13:40 -!- ebowden [~ebowden@CPE-101-180-233-178.lnse3.cha.bigpond.net.au] has quit [Changing host] 13:40 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 13:41 < jrayhawk_> which may simply be HPA upregulation lowering inflammation 13:45 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##hplusroadmap 15:33 -!- Orpheon [~Orpheon@213.200.193.129] has quit [Read error: Connection reset by peer] 16:01 < nmz787_i> yay for all-day long meetings 16:12 < kanzure> i hear your employer is really good at meetings 16:21 < FourFire> nmz787_, are the meetings permitting you to do anything? 16:28 < nmz787_i> i was allowed to sit, eat, drink water/coffee/orange-juice 16:28 < nmz787_i> I guess I was allowed to surf the web, though I guess it would be looked down upon 16:28 < nmz787_i> we are planning the next 12 weeks of work 16:29 < nmz787_i> so I guess it is allowing me to better estimate my ability to produce code 16:29 < nmz787_i> I guess 16:30 -!- nmz787_i [~ntmccork@134.134.139.70] has quit [Quit: Leaving.] 16:55 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Remote host closed the connection] 17:03 < FourFire> nmz787_, so not entirely wasted? 17:24 -!- ebowden [~ebowden@1.136.96.82] has joined ##hplusroadmap 17:24 -!- ebowden [~ebowden@1.136.96.82] has quit 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[~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 18:09 -!- FourFire [~fourfire@81.4.122.176] has quit [Ping timeout: 256 seconds] 18:09 -!- yorick [~yorick@oftn/oswg-member/yorick] has quit [Remote host closed the connection] 18:10 -!- yorick [~yorick@oftn/oswg-member/yorick] has joined ##hplusroadmap 18:15 -!- FourFire [~fourfire@81.4.122.176] has joined ##hplusroadmap 18:21 -!- nmz787_i [ntmccork@nat/intel/x-tygftjyocuuirtgw] has quit [Quit: Leaving.] 18:24 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-222-194.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 260 seconds] 18:28 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 18:37 -!- ebowden [~ebowden@1.136.96.82] has joined ##hplusroadmap 18:37 -!- ebowden [~ebowden@1.136.96.82] has quit [Changing host] 18:37 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 19:06 -!- ebowden_ [~ebowden@2001:8003:1163:5800:1108:52b1:2dba:ddda] has joined ##hplusroadmap 19:06 -!- ebowden_ [~ebowden@2001:8003:1163:5800:1108:52b1:2dba:ddda] has quit [Changing host] 19:06 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 19:09 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds] 19:19 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 19:32 < fenn> .wik MPTP 19:32 < yoleaux> "MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a prodrug to the neurotoxin MPP+, which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain. It has been used to study disease models in various animal studies." — https://en.wikipedia.org/wiki/MPTP 19:33 < fenn> not sure what that has to do with blood brain barrier dysfunction 19:35 < fenn> "MPP+ interferes with complex I of the electron transport chain, a component of mitochondrial metabolism, which leads to cell death and causes the buildup of free radicals" 19:49 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 19:56 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Read error: Connection reset by peer] 20:13 -!- justanotheruser is now known as justanother|CHI 20:13 -!- Jen__ [~Jen@cpc76808-brmb10-2-0-cust35.1-3.cable.virginm.net] has quit [Ping timeout: 250 seconds] 20:16 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 20:24 -!- justanother|CHI is now known as justanother|LBS 20:26 -!- justanother|LBS is now known as justanother\_ub 20:39 -!- AmbulatoryCortex [~Ambulator@173-31-155-69.client.mchsi.com] has quit [Read error: Connection reset by peer] 20:39 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Read error: Connection reset by peer] 20:40 -!- ebowden [~ebowden@war2000509.lnk.telstra.net] has joined ##hplusroadmap 20:40 -!- ebowden [~ebowden@war2000509.lnk.telstra.net] has quit [Changing host] 20:40 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 20:53 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 20:54 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 20:55 -!- justanother\_ub [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 256 seconds] 20:59 -!- ebowden [~ebowden@shelto3.lnk.telstra.net] has joined ##hplusroadmap 20:59 -!- ebowden [~ebowden@shelto3.lnk.telstra.net] has quit [Changing host] 20:59 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 21:13 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 21:15 -!- ebowden [~ebowden@shelto3.lnk.telstra.net] has joined ##hplusroadmap 21:15 -!- ebowden [~ebowden@shelto3.lnk.telstra.net] has quit [Changing host] 21:15 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 21:45 -!- drewbot_ [~cinch@ec2-54-224-81-166.compute-1.amazonaws.com] has quit [Remote host closed the connection] 21:45 -!- drewbot [~cinch@ec2-23-20-238-23.compute-1.amazonaws.com] has joined ##hplusroadmap 22:09 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] 22:10 -!- augur [~augur@2601:645:4100:15f2:4439:d0ea:375d:a0a8] has joined ##hplusroadmap 22:13 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-wsxdhtnhfqzzckco] has quit [Quit: Connection closed for inactivity] 22:27 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 22:58 -!- augur [~augur@2601:645:4100:15f2:4439:d0ea:375d:a0a8] has quit [Remote host closed the connection] 22:59 -!- Orpheon [~Orpheon@213.200.193.129] has joined ##hplusroadmap 23:00 -!- Orpheon [~Orpheon@213.200.193.129] has quit [Client Quit] 23:03 -!- Orpheon [~Orpheon@213.200.193.129] has joined ##hplusroadmap 23:03 < kanzure> hrm 23:03 -!- ebowden [~ebowden@2001:8003:1163:5800:693a:6a58:751f:9074] has joined ##hplusroadmap 23:03 -!- ebowden [~ebowden@2001:8003:1163:5800:693a:6a58:751f:9074] has quit [Changing host] 23:03 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 23:24 -!- nnnn20431 [~nnnn20430@plfgr.eu.org] has joined ##hplusroadmap 23:38 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 23:40 -!- strangewarp [~strangewa@c-76-25-206-3.hsd1.co.comcast.net] has joined ##hplusroadmap 23:54 -!- ebowden [~ebowden@2001:8003:1163:5800:7d5c:aa27:a6bb:5351] has joined ##hplusroadmap 23:54 -!- ebowden [~ebowden@2001:8003:1163:5800:7d5c:aa27:a6bb:5351] has quit [Changing host] 23:54 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap --- Log closed Wed Nov 02 00:00:38 2016