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[~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 07:02 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds] 07:06 -!- sandeepkr [~sandeepkr@103.49.155.114] has quit [Read error: Connection reset by peer] 07:07 -!- sandeepkr [~sandeepkr@103.49.155.114] has joined ##hplusroadmap 07:12 -!- Psyber [~kingp@203.94.46.104] has joined ##hplusroadmap 07:15 -!- ebowden [~ebowden@CPE-101-180-233-178.lnse3.cha.bigpond.net.au] has joined ##hplusroadmap 07:15 -!- ebowden [~ebowden@CPE-101-180-233-178.lnse3.cha.bigpond.net.au] has quit [Changing host] 07:15 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 07:17 -!- Psyber [~kingp@203.94.46.104] has quit [Ping timeout: 260 seconds] 07:20 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e3007947 Bryan Bishop: resistance to sleep deprivation >> http://diyhpl.us/diyhpluswiki/genetic-modifications/ 07:20 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=f1e3e495 Bryan Bishop: add more links to mimblewimble transcript >> http://diyhpl.us/diyhpluswiki/transcripts/sf-bitcoin-meetup/2016-11-21-mimblewimble/ 07:20 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=2d79938c Bryan Bishop: also describe how to spend small utxos in bitcoin >> http://diyhpl.us/diyhpluswiki/bitcoin/somewhat-open-problems-draft/ 07:44 < kanzure> "N-acetylcysteine inhibits muscle fatigue in humans" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC330079/pdf/jcinvest00490-0298.pdf 08:01 -!- Gurkenglas_ [~Gurkengla@dslb-188-106-181-165.188.106.pools.vodafone-ip.de] has quit [Ping timeout: 246 seconds] 08:05 < kanzure> .wik delta sleep-inducing peptide 08:05 < yoleaux> "Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities." -- https://en.wikipedia.org/wiki/Delta_sleep-inducing_peptide 08:06 < kanzure> 'humoral transmission of sleep' http://link.springer.com/article/10.1007/BF00583718 (doesn't seem to work that well?) 08:25 < kanzure> "Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia" http://www.pnas.org/content/113/45/12826.short 09:01 -!- M4l3z [~M4l3z@LFbn-1-4220-37.w92-169.abo.wanadoo.fr] has quit [Remote host closed the connection] 09:06 -!- Gurkenglas_ [~Gurkengla@dslb-188-106-181-165.188.106.pools.vodafone-ip.de] has joined ##hplusroadmap 09:11 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 09:29 -!- xaft [~nope@unaffiliated/xaft] has quit [Quit: Bye] 09:53 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: hacked by DNC] 09:55 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 10:32 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has quit [Quit: No Ping reply in 180 seconds.] 10:34 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 11:00 < kanzure> 'whole cortex electrophysiology' 11:49 -!- jtimon [~quassel@186.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 11:51 -!- _0bitcount [~Big_Byte@92.176.142.156] has joined ##hplusroadmap 12:00 < kanzure> https://en.wikipedia.org/wiki/Hamster_zona-free_ovum_test 12:09 < justan0theruser> cool, now I need some hamsters 12:11 < kanzure> not if you're fertile 12:21 < kanzure> "well i have good news nad i have bad news..." 12:46 < JayDugger> Good news, you're fertile. Bad news, the hamster is suing. 12:54 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 12:56 < kanzure> such is life 13:01 < kanzure> "Contrary to some assertions by medical professionals, if the human sperm penetrates the hamster egg, a hybrid embryo is indeed created. The resulting hamster-hybrid is known as a humster." 13:03 < JayDugger> Not touching that. 13:15 < kanzure> "The predictive value of the zona-free hamster egg penetration test in relation to in-vitro fertilization at various insemination concentrations" https://humrep.oxfordjournals.org/content/13/3/624.full.pdf 13:15 < kanzure> "Thalamic reticular nucleus induces fast and local modulation of arousal state" https://elifesciences.org/content/4/e08760 13:15 < kanzure> "Here, using optogenetics and whole cortex electrophysiology, we show that local tonic activation of thalamic reticular nucleus (TRN) rapidly induces slow wave activity in a spatially restricted region of cortex. These slow waves resemble those seen in sleep, as cortical units undergo periods of silence phase-locked to the slow wave. Furthermore, animals exhibit behavioural changes consistent ... 13:15 < kanzure> ...with a decrease in arousal state during TRN stimulation. We conclude that TRN can induce rapid modulation of local cortical state." 13:16 < kanzure> "Electrical stimulation of the ventral tegmental area induces reanimation from general anesthesia" http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1917619 13:44 < kanzure> "Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci" http://biorxiv.org/content/early/2016/02/02/031369 PAX8 and VRK2 13:50 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=f8eec0ff Bryan Bishop: also TNFα G308A polymorphism for resistance to sleep deprivation >> http://diyhpl.us/diyhpluswiki/genetic-modifications/ 13:50 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=d65be399 Bryan Bishop: also sleep duration >> http://diyhpl.us/diyhpluswiki/genetic-modifications/ 14:26 -!- mabel [~andares@unaffiliated/jacco] has quit [Ping timeout: 256 seconds] 14:28 < kanzure> "I think megabase-scale genome assembly can be evolved in single cells... the easiest path I can see experimentally... definitely will work, question of sequence space and scaffolding... if I think of something better I'll let you know." 14:28 < kanzure> "and yeah, like a genome geared toward Gibson assembly... you could get that... select for it too... shoot 1e5 100mers into the right (maybe eukaryotic?) bug... would need to carefully chart the selections and de-selections but I can see it working" 14:44 -!- Douhet [~Douhet@unaffiliated/douhet] has quit [Ping timeout: 248 seconds] 14:48 -!- Douhet [~Douhet@unaffiliated/douhet] has joined ##hplusroadmap 14:53 -!- _0bitcount [~Big_Byte@92.176.142.156] has quit [Quit: Leaving] 15:03 -!- andares [~andares@2607:fb90:837a:fdb6:2d1a:6d1b:55eb:49fc] has joined ##hplusroadmap 15:03 -!- andares [~andares@2607:fb90:837a:fdb6:2d1a:6d1b:55eb:49fc] has quit [Changing host] 15:03 -!- andares [~andares@unaffiliated/jacco] has joined ##hplusroadmap 15:24 -!- chris_99 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[~M4l3z@LFbn-1-4220-37.w92-169.abo.wanadoo.fr] has quit [Client Quit] 18:51 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:c9ad:3c39:7a06:dafa] has joined ##hplusroadmap 18:55 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has quit [Quit: No Ping reply in 180 seconds.] 18:56 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 19:04 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Read error: Connection reset by peer] 19:05 < kanzure> .tw https://twitter.com/AndrewHires/status/802542688511766528 19:05 < yoleaux> EM Drive thrust effect may be due to thermal expansion? Shouldn't this be on @PubPeer instead of a reddit thread? https://np.reddit.com/r/Physics/comments/5ewj86/so_nasas_em_drive_paper_is_officially_published/dafqhw2/ (@AndrewHires) 19:30 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-eywlcjbirvbgxncd] has quit [Quit: Connection closed for inactivity] 20:01 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 20:13 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 20:15 -!- Darius [~quassel@cpe-158-222-160-123.nyc.res.rr.com] has quit [Remote host closed the connection] 20:16 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 260 seconds] 20:22 -!- Gurkenglas_ [~Gurkengla@dslb-188-106-181-165.188.106.pools.vodafone-ip.de] has quit [Ping timeout: 246 seconds] 20:58 < fenn> the reddit thread boils down to "but look at the curve, it's a classic cooling curve!" when almost half of the paper is spent discussing thermal expansion and how to subtract out the cooling curve 20:59 < fenn> i don't understand how that soldered copper foil piece of crap costs $13k to fabricate 21:00 < fenn> er, maybe they were talking about a different apparatus 21:02 -!- Aurelius [~cpopell@50.35.79.117] has quit [Ping timeout: 260 seconds] 21:04 < fenn> anyway they should have included a cylindrical control 21:09 < ybit> there has to be negative consequenceswhen you remove the link between circadian rhythms and sleep. i'll have to read the paper now :) 21:09 < fenn> they should be directly comparing on-resonance vs off-resonance curves to determine "thrust" 21:10 < fenn> if the power level is the same, the thermal expansion should be the same 21:10 -!- Aurelius [~cpopell@50.35.79.117] has joined ##hplusroadmap 21:11 < ybit> ah, or just the quote from kanzure 21:15 < fenn> "a cavendish balance approach properly designed to allow very large rotation angles such as 90, 180, or 360 degrees will not be susceptible to this kind of thermal false positive" well then why the fuck didn't you just build that instead 21:16 < fenn> ugh this paper is not even wrong 21:36 < fenn> .wik john michell 21:36 < yoleaux> "John Michell (25 December 1724 - 29 April 1793) was an English clergyman and natural philosopher who provided pioneering insights in a wide range of scientific fields, including astronomy, geology, optics, and gravitation." -- https://en.wikipedia.org/wiki/John_Michell 21:36 < fenn> john michell was the actual inventor of "the cavendish balance" 21:37 < fenn> a very sensitive torsion pendulum 21:38 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-ujukrediqmkxxvtu] has joined ##hplusroadmap 21:54 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has quit [Quit: No Ping reply in 180 seconds.] 21:54 < __mz_o> ybit: ive read report regarding circadium rhythms and carcinogenesis 21:55 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 21:59 < __mz_o> ybit: http://www.medscape.com/viewarticle/715702 22:05 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has quit [Quit: No Ping reply in 180 seconds.] 22:06 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 22:08 -!- Guest79488 [~abe@68.175.143.22] has quit [Ping timeout: 260 seconds] 22:15 < kanzure> .title 22:15 < yoleaux> Medscape: Medscape Access 22:15 < kanzure> bleh 22:16 < __mz_o> .title http://ar.iiarjournals.org/content/32/7/2747.long 22:16 < yoleaux> Role of Melatonin in Cancer Treatment 22:18 -!- jtimon [~quassel@186.31.134.37.dynamic.jazztel.es] has quit [Ping timeout: 250 seconds] 22:31 -!- Douhet [~Douhet@unaffiliated/douhet] has quit [Ping timeout: 248 seconds] 23:14 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] --- Log closed Sun Nov 27 00:00:22 2016