--- Log opened Wed Dec 07 00:00:31 2016
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05:30 < ebowden> nmz787, __mz_0, DLC is diamond like carbon. When it is pure and of high quality, it is carbon bonded in the manner of diamond but without long-range order, it is amorphous. It can be as hard as diamond, yet not brittle.
05:36 < kanzure> kelu124: you ded?
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07:24 < kanzure> http://www.sciencemag.org/news/2016/12/crispr-patent-hearing-produces-no-clear-winner-only-soft-signals
07:25 < kanzure> "In the most colorful moment on the UC side, its lead attorney, Todd Walters, three times said "there was no special sauce here." He noted that Zhang was one of six labs that showed CRISPR worked in eukaryotes within 6 months of the Doudna-Charpentier paper. Doudna indeed was one of those labs. But the Broad-lead counsel, Steven Trybus, countered that even Doudna acknowledged in a press ar...
07:25 < kanzure> ...ticle that "she experienced 'many frustrations' getting CRISPR to work in human cells." Walters insisted the Doudna never made any statement that it wouldn't work in eukaryotic cells, and indeed the broadly worded UC patent includes eukaryotic applications. What's more, Walters said any time scientists perform experiments they have reasonable expectations of success or they'd mod...
07:25 < kanzure> ...ify it."
07:25 < cluckj> a lawyer saying "special sauce" is really neat
07:26 < kanzure> ".. noting that one judge pointed out that there's a difference between expectation and hope."
07:31 < kanzure> i hopexpect not
07:42 < cluckj> same
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08:21 < chris_99> http://www.smh.com.au/technology/sci-tech/nightvision-glasses-nanocrystals-developed-at-anu-allow-direct-vision-into-the-infrared-20161207-gt5vsf.html sounds very cool
08:30 < kanzure> https://console.aws.amazon.com/polly/home/SynthesizeSpeech
08:41 < __mz_o> i just saw that the other day
08:41 < __mz_o> you can save the audio files. pretty cool imo
08:41 < __mz_o> the lex service is interesting to
08:42 < __mz_o> thats their speech-to-text service
08:43 < __mz_o> If i had a clone, he'd be learning their ML library to
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09:22 < nmz787_w> why don't we have GMO insects that will scratch and clean my head for me?
09:23 < nmz787_w> they'd eat the dead skin and lick up any skin oil, and maybe exude a nice essential oil for perfuming
09:24 < nmz787_w> I guess they could also exude some topical anesthetic too, or something like aftershave, to make your head feel nice and fresh
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09:27 < nmz787_w> actually, why don't bedbugs yet clean our entire  body while we sleep??? those lazy moocher bugs
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09:28 < chris_99> haha
09:28 < cluckj> I am down with some GMO head lice
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09:58 < CaptHindsight> GMO insects as weapons
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10:00 < CaptHindsight> guess that might be covered by the https://www.un.org/disarmament/wmd/bio/
10:01 < nmz787_w> weapons against swampbutt
10:01 < CaptHindsight> but why not a dust mite skin cream?
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10:13 < CaptHindsight> I was actually contacted by a clothing co that is looking for similar tech using coatings for textiles
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10:14 < CaptHindsight> how to keep socks and poopoo undies from stinking
10:15 < CaptHindsight> can you do it with a coating that stays on the fabric?
10:15 < CaptHindsight> can it survive a wash?
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10:46 < nmz787_w> clothing with catalytic platinum sites, or enzymes that were sturdy enough, or just sell washing detergen with microbes like outdoors stores do, but with some microbe that stays on the clothes waiting to breathe farts
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10:59 < CaptHindsight> microbes on tethers
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11:00 < CaptHindsight> titanium as well but it also breaks down the polymers used to bond it to the fabric
11:01 < CaptHindsight> the trick is really finding some middle ground, tech that they buy for a low price that somewhat works
11:03 < CaptHindsight> they can sell without false advertisement and they can mark up the margins on
11:06 < nmz787_w> space suit for daily living, that is filled with bacterial ooze
11:07 < nmz787_w> don't leave home without your statis-suit!
11:07 < CaptHindsight> iSuit
11:08 < CaptHindsight> nmz787_w: McDonalds make clothing?
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11:29 < nmz787_w> I mean stasis-suit :/
11:29 < nmz787_w> s/mean/meant/
11:30 < nmz787_w> this keyboard either has battery issues, or wireless comms issues
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13:17 < nmz787_w> kanzure: know anyone needing node.js work done for $, asking for a friend
13:17 < nmz787_w> oh, wait
13:17 < nmz787_w> maybe he is looking for someone to do node.js work
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13:18 < kelu124> Hey there from the murgen (DIY ultrasound dev kit) guy ;)
13:19 < kanzure> howdy
13:19 < kanzure> could you give us a status update about murgen things?
13:19 < kelu124> Hi Kanzure
13:20 < kelu124> Humm things are moving on, the kit was redesigned to be used as two breadboard modules, cheaper, lighter, and using more off-the-shelf components
13:20 < kelu124> like using a STM32 on a arduino-compatible wifi adafruit board
13:21 < kelu124> made quite some progress as well on the documentation (shifted from a github manually written to documentation-generating script
13:21 < kelu124> and got the boards on tindie, having some orders already and people using those
13:22 < kanzure> i think our version at one point was planned to use the project icestorm fpga stuff
13:22 < kelu124> got some prize from hackaday too, quite fun
13:22 < kelu124> in short, moving forward =)
13:22 < kanzure> ( https://docs.google.com/document/d/1xvLWDbp0x6z0Ft3AsfxjIsLUNsg5smkTcYb1g4WVo5U/edit )
13:22 < kelu124> saw it recently on HAD at http://hackaday.com/2016/11/05/give-your-rpi-a-cool-fpga-hat/
13:22 < kanzure> i'm a little disappointed in google docs, seems that it did not notify me of your comment on the google doc :o
13:23 < kelu124> "><
13:23 < kanzure> i think we were doing a very basic motor sweep implementation
13:24 < kanzure> and i really want to move towards various phased array approachs for both imaging and stimulation
13:24 < kelu124> yup, I was using both servos and retrofitted probes
13:24 < kelu124> but using multi-channels AFE + FPGA can help bring more channels
13:24 < kelu124> seen some prototypes with a couple of FPGA onboard
13:25 < kelu124> some for channels management, some for beamforming, some for signal acquisition/processing
13:25 < kanzure> fenn: it looks like our html logger went offline the other day. also, it picked up various opentimestamps files (ots).
13:25 < kelu124> but quite unavoidable on multi-element arrays
13:26 < kanzure> prototypes of a derivative of murgen, or what prototypes were those?
13:27 < kelu124> none, just a review from the litterature
13:27 < kanzure> aww. okay.
13:27 < kanzure> yes, lots of fun stuff in the literature
13:27 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/ultrasound/
13:27 < kanzure> http://diyhpl.us/~bryan/papers2/ultrasound/
13:27 < kelu124> Put the more relevant stuff in a recent publi (https://arxiv.org/pdf/1611.10174.pdf)
13:28 < kanzure> .title https://arxiv.org/abs/1611.10174
13:28 < yoleaux> [1611.10174] A low-cost, arduino-like dev-kit for single-element ultrasound imaging
13:29 < kanzure> yeah i think everyone should have these next to their toothbrush
13:30 < kanzure> (various not-for-human-use disclaimers go here)
13:30 < kelu124> There's not only imaging, but some other uses can be interesting -- biofeedback for example for stroke-recovering patients, or bodyfat measurement by getting A-mode lines at 4 or 5 body points
13:31 < kelu124> It's a shame very little was done in terms of open hardware on the topic so far
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13:31 < kanzure> there was an old technique where ultrasound was used for whole body imaging
13:32 < kanzure> essentially the same way that x-ray tomography works (spin a bunch of emitters around a body, collect data)
13:32 < kelu124> in a water/immersion bath I guess
13:32 < kanzure> yes it was the barrel of a.. er.. let me look it up.
13:32 < kelu124> Could be interesting to get both reflected and transmitted signal, maybe the source of some additional information.
13:33 < kelu124> Radon-transform, and you get the image
13:33 < kanzure> 19:17 < kanzure> 19:49 < fenn> The first full-body human ultrasound -- conducted in the turret of a disused B-29 bomber  http://criticalmedia.uwaterloo.ca/courses/necromedia/
13:33 < cluckj> plz be a barrel of undisclosed goo
13:34 < kanzure> kelu124: yep, lots of interesting things can be done with ultrasound contrast agents too -- materials matter, especially for in vivo measurements. but also, external materials can be highly useful -- thus why people use contact gels.
13:35 < kelu124> Not only contrast agent, or impedance adaptation gels, but also the materials for the scanner heads encasing, which need to be transparents at those frequencies
13:35 < kelu124> Plus, in terms of ultrasound contrast agents, there were works on local drugs delivery, where bubbles transport the agent, and get popped using ultrasound when they reach a specific site
13:36 < kanzure> for single motor scan, the hardware is obvious/simple, but do you have anything about the more exotic ultrasound emitters by any chance
13:36 < kanzure> yep i'm familiar with (micro)bubble delivery
13:36 < kelu124> ( https://www.researchgate.net/publication/309767553_Subwavelength_far-field_ultrasound_drug-delivery )
13:37 < kanzure> looks recent
13:38 < kelu124> for arrays, I was willing to try at first single channel imaging, using synthetic aperture : you get a poor framerate, but electronics is reaaaally simple
13:38 < kanzure> "synthetic aperture"?
13:40 < kelu124> The wikipedia page is not too bad. Basically, you study the signals produced by pairs of single emitter / single receiver on an array, then combine those to reproduce your image.
13:40 < kanzure> okay, "use math, not hardware"
13:40 < kelu124> Based on the superposition linearity
13:41 < kelu124> exactly. You loose on the framerate, but win on simplicity, and sometimes quality.
13:42 < kelu124> An exciting alternative would be to use time-reversal (time mirrors) using a single element, generating a signal reflected back to the middle to be imaged. I'm quite sure that with a proper training of your scanner, you'd be able to get full field, awesome framerate, quite accurate, images.
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13:42 < kelu124> you won't need an array and FPGAs, just maths, at the extreme.
13:43 < kanzure> with icestorm, FPGAs aren't as much black magic or off-limits anymore, although i do acknowledge the benefits of attempting to avoid FPGAs
13:44 < delinquentme> So theres a piezeo in this ultrasound scanner?
13:44 < kelu124> -see http://slideplayer.com/slide/7645366/ )
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13:44 < kanzure> .title
13:44 < yoleaux> Building Three-Dimensional Images Using a Time-Reversal Chaotic Cavity Gabriel Montaldo, Delphine Palacio, Mickael Tanter, and Mathias Fink IEEE Transactions. - ppt download
13:45 < kelu124> It really depends on what you want/need as a type of signal. I'm quite the proponent for "keeping it as simple a possible".
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13:49 < kanzure> your paper says a scanning head is still TODO?
13:50 < kanzure> a non-mechanical scan maybe?
13:50 < kanzure> oh okay, a non-water immersion scanning head
13:59 < kelu124> Oops I've kept a TODO ?
14:00 < kelu124> AH okay. Yes, a non-water immersion.
14:00 < kelu124> Materials are quite an issue for this matter, that's why I've tried commercial probes for piezo+movement.
14:01 < kanzure> what's the price on the commercial probes?
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14:10 < nmz787_w> sounds like an opportunity for you though, re : (1:31:11 PM) kelu124: It's a shame very little was done in terms of open hardware on the topic so far
14:12 < kelu124> =)
14:13 < nmz787_w> icestorm is only useful for glue logic and small logic from what I've heard
14:13 < kelu124> True, nmz787_w - though I'm missing the second step before step 3. Profit =)
14:13 < nmz787_w> i don't think you'd get any math or crypto boost with one
14:13 < kelu124> kanzure: I can find the used probes I'm using on ebay at around 70$
14:14 < nmz787_w> also, I'm slowly learning SystemVerilog now, during part of my day job
14:14 < kanzure> ah. but mass purchase of them..?
14:14 < nmz787_w> kelu124: aliexpress?
14:17 < kelu124> Today, it's rather Tindie, given the volume of users ;)
14:34 < kelu124> There's also the option of using a DSP to do some processing, and keeping a relatively microcontroler
14:37 < nmz787_w> kelu124: have you looked for probes on aliexpress?
14:38 < nmz787_w> I bought an Intel ComputeStick with the m5 processor in a week ago, and it packs a wallop for its small size
14:39 < nmz787_w> my point is, finding small powerful and cheap computers is getting easier and easier
14:43 < kelu124> Indeed. Even the Pi zero may have enough power. I've been playing as well with the beaglebone black and matching ADC, up to 40Msps, with a 350Mb buffer for acquisition, quite powerful.
14:44 < nmz787_w> I have yet to really play with my LPC link v2 with the 80 MSPS ADC (though only something like 7 or 8 bits)
14:50 < kelu124> if you have some analog log compression, you don't really need much more
14:51 < kelu124> the human eye cannot distinguish between a lot of level of gray
14:51 < nmz787_w> yeah but software might be able to do something... zoom in maybe?
14:52 < nmz787_w> would there be a way to image the insides of walls of a building?
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14:52 < nmz787_w> I could sure use an easy way to see where to rip out drywall and drill through wood, etc, for new wiring and renovation formulation/research/preparation
14:53 < kelu124> zoom in would still be limited by the sensor resolution
14:53 < kelu124> NDT uses a lot of ultrasound, I've heard some as well for walls control
14:53 < kelu124> but haven't seen much
14:54 < kelu124> got to go, was a pleasure touching base! Will keep an eye on the logs
14:54 < kanzure> cool, talk soon
14:55 < kanzure> facebook should do a mutantpedia--- collect everyone's genome, then ask them what their special mutant powers are
14:56 < kanzure> also, it would be trivial to identify a million+ people that do well on <5 hours of sleep/night
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14:58 < kanzure> also it might be possible to genetically remove hunger pangs
15:00 < kanzure> someone suggests that mutant DEC2 could be delivered orally
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15:00 < kanzure> DEC2 mutation is like a 40% lifespan increase (at last in terms of active time awake)
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15:01 < kanzure> that's probably the biggest longevity impact that we know about right now, by many orders of magnitude
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15:16 < nmz787_w> orally eh?
15:16 < nmz787_w> so post-birth?
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15:22 < kanzure> well i was previously thinking of CRISPR + lentivirus of adults, which is post-birth too
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15:30 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/sleep/
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15:58 < kanzure> http://www.ligandal.com/ "'Gene therapy requires delivery. Ligandal has developed a breakthrough nanotechnology for the precise and high-efficiency delivery of nucleic acids (CRISPR, TALEN, and RNA) to specific cells and organelles without the limitations of viruses, enabling a new standard for genetic medicine. '"
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16:05 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=ae0c8970 Bryan Bishop: milano allele >> http://diyhpl.us/diyhpluswiki/genetic-modifications/
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16:07 < kanzure> http://blog.gen9bio.com/largest-synthetic-virus-could-be-a-breakthrough-in-treating-cancer
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16:13 < kanzure> whatever happened to Lemminkainen?
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16:14 < kanzure> 'apparently very rare antibodies have been found in people that confer complete resistance to all influenza variants'
16:16 < kanzure> ah he was cofounder of ligandal. i didn't know that.
16:19 < TMA> he has apparently drowned in the river of Tuonela
16:21 < kanzure> what?
16:23 < TMA> according to wikipedia, Lemmink?inen drowned in a river in Tuonela (the Underworld), his body was found by his mother. she has resurrected him afterwards
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16:28 < kanzure> no, the other one. from hplusroadmap.
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16:30 < kanzure> "phage-assisted continuous evolution" (PACE) http://www.sculptingevolution.org/pace
16:30 < kanzure> "During phage-assisted continuous evolution (PACE), we harness the fastest-evolving replicator in nature, the bacteriophage, to continuously evolve proteins or nucleic acids toward desired functions in vivo.  We link the phage's ability to reproduce to the desired molecular activity by moving a gene required for phage infection (gene III) from the phage genome into the host cell and replacing ...
16:31 < kanzure> ...it with the gene(s) we want to evolve.  We then engineer the host cell to produce the missing phage protein (pIII) in proportion to the desired activity."
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16:36 < kanzure> as a precursor to homologous recombination for DNA assembly, perhaps it would be useful to select for cells that are able to combine just two input DNA fragments--- i think homologous recombination presently is done with more than this?
16:44 < kanzure> ok i think i should go find a yeast person
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16:58 < kanzure> "Parallel in vivo DNA assembly by recombination: Experimental demonstration and theoretical approaches" http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056854
17:04 < kanzure> also http://diyhpl.us/~bryan/papers2/bio/Recent%20advances%20in%20DNA%20assembly%20technologies%20-%202015.pdf
17:05 < kanzure> ah "counter-selection markers": if the organism assembles the DNA wrong, then you could have it express some kind of poison, or a bright signal that would allow for FACS to sort out that cell and deselect it
17:11 < nmz787_w> I remember being a fan of PACE when I first saw it
17:11 < kanzure> did you change your mind?
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17:22 < nmz787_w> no, just never had the initial DNA and also microfluidics, along with analytic equipment to put an evolver together
17:26 < kanzure> kent wants to do lots of evolver projects. and so do i. the trick is to find good targets to work on.
17:40 < kanzure> .wik cotard delusion
17:40 < yoleaux> "Cotard delusion is a rare mental illness in which the affected person holds the delusional belief that they are already dead, does not exist, is putrefying, or has lost their blood or internal organs." -- https://en.wikipedia.org/wiki/Cotard_delusion
17:41 < kanzure> "paradoxically, 55% of the patients present delusions of immortality"
17:41 < kanzure> i wonder if those delusions were tested
17:42 < kanzure> and how would you correctly test a "delusion of immortality" anyway...? wtf
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17:48 < TinKode> idk guys i cannot get over the idea that we live in a simulation. i mean it should be obvious by now
17:49 < TinKode> every elegant simulation should allow for simulations within
17:50 < kanzure> what would it matter if we did?
17:50 < TinKode> additionally we just start to barely scratch the idea of quantum entanglement
17:50 < kanzure> TinKode: i dunno who you are, but here's something to get you stuck http://lesswrong.com/lw/n1r/timeless_quantum_immortality/ (i hate this stuff)
17:50 < TinKode> suggesting something like the matrix where everything is interconnected at some basic level
17:50 < TinKode> kanzure, thx gonna check
17:51 < TinKode> kanzure, it matters because that makes me wonder who is the Simulator
17:51 < kanzure> wouldn't you wonder that anyway, though?
17:52 < TinKode> what would be rather is purpose is more interesting to contemplate
17:52 < TinKode> his*
17:53 < TinKode> kanzure, what would be one of the reasons you hate that stuff?
17:54 < TinKode> does it conflict with your inner sense of naturalism?
17:54 < kanzure> it doesn't cause its adherents to be productive individuals
17:54 < kanzure> hence it is hateworthy
17:56 < cluckj> haha
17:57 < TinKode> also the idea of free will goes off the charts in that deterministic view
17:57 < cluckj> philosophy alert
17:57 < TinKode> sure you just wrote that out of free will
17:57 < kanzure> why are you here
17:58 < TinKode> to understand my purpose
17:58 < kanzure> you chose this channel for that...?
17:58 < cluckj> your purpose is to pass butter
17:59 < TinKode> cluckj, i identified your purpose: trolling
17:59 < kanzure> TinKode: https://www.youtube.com/watch?v=ekP0LQEsUh0
17:59 < cluckj> that's probably accurate in this case
17:59 < kanzure> but yes, we really do have a no philosophy rule
17:59 < kanzure> TinKode: http://diyhpl.us/wiki/hplusroadmap
17:59 < TinKode> like transhumanism is 100% philosophy free... sure
18:00 < cluckj> I violate the no philosophy rule so frequently and egregiously; I am familiar with the intricacies...
18:04 < kanzure> TinKode: what's wrong with determinism, again?
18:04 < nmz787_w> TinKode: gotta understand the system no matter what level you start at
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18:05 < kanzure> yashgaroth: i'm still confused why nobody knows about homologous recombination
18:05 < TinKode> it kind of imposes a certain limit on the way of thinking
18:05 < TinKode> "Quantum Immortality states that my consciousness will follow the path of branchings in which it survives"
18:05 < TinKode> what state of mind determines that
18:06 < TinKode> how does my consciousness know which combination of thoughts determines survival
18:07 < yashgaroth> kanzure yeah me too; I mean my proposed diagram relies on the exonuclease working perfectly, and I guess fragments with one single-stranded overhang aren't as commonly used as straight ssDNA or dsDNA
18:08 < cluckj> it doesn't know which combination works, the idea behind quantum immortality is more than that
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18:09 < TinKode> also how outdated is the idea that consciousness affects matter? (over the internet too)
18:09 < TinKode> https://www.youtube.com/watch?v=nRSBaq3vAeY
18:10 < TinKode> so which is first matter affects consciousness or the other way around?
18:11 < kanzure> TinKode: keep in mind that i linked that as an example of bullshit
18:11 < TinKode> kanzure, a so by extension all of my approaches are under the possibilty to be considered bs
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18:13 < nmz787_w> kanzure: lots of people know about homologous recombination
18:15 < kanzure> nmz787_w: did you see the thing about using it for dna assembly from many 100mers?
18:22 < TinKode> What is the chance of a cell to pop out a sea?
18:27 < TinKode> Basically nil guys... even if the cell were able to exist in order to survive would have to develop and perfect the system of cellular division in one life spawn. I would doubt strongly doubt it could be possible.
18:28 < cluckj> zzz
18:29 < yashgaroth> shit he's right, brb converting to religion
18:30 < TinKode> sure constructive criticism at its finest
18:31 < kanzure> making things is more important than philosophy
18:31 < cluckj> ^
18:31 < TinKode> make for what
18:31 < yashgaroth> usually when someone states that life couldn't have evolved from nothing blah blah, it's rather difficult to change their mind
18:31 < cluckj> ^^
18:31 < TinKode> you dont say
18:31 < kanzure> determinism isn't some sort of death sentence. you don't even know the current state, much less all the possible state modifications.
18:32 < cluckj> determinism is boring, to boot
18:32 < kanzure> nah
18:32 < yashgaroth> current biological theory states that simple RNA-based lifeforms, given millions of years and no competition since there's no other life, could eventually create a self-propagating "cell"
18:32 < cluckj> IDIC, dude
18:32 < yashgaroth> or we're all making it up in order to get grant money and god(s) will be very angry with us after death
18:33 < __mz_o>  
18:33 < kanzure> i don't know what yashgaroth thinks he is replying to
18:33 < yashgaroth> yeah me either
18:33 < kanzure> oh, you interpreted TinKode as asking about origin of self-replication?
18:33 < TinKode> alright now im sure this is the wrong channel... it took me just a few more words to read
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18:34 < kanzure> TinKode: this is the "holy fuck let's upload everyone into computers and destroy the planet" channel
18:34 < TinKode> 4 real?
18:34 < yashgaroth> I mean it's hard to get a definite point from schizophrenics or w/e, but yeah that was my ill-fated intent
18:34 < TinKode> like that movie
18:34 < TinKode> transcendence
18:34 < TinKode> with depp
18:34 < cluckj> and not even in that particular order, sometimes
18:35 < yashgaroth> how me a cell, pop out the sea??
18:35 < TinKode> or the eye or the plasma
18:35 < kanzure> origin of self-replication is easy to explain from a string manipulation standpoint-- random string operations are easy to posit, and self-replication is a consequence of some ligation (combination) and other properties
18:35 < yashgaroth> ooh the eye is an interesting case study, but fuck off
18:36 < TinKode> ok will fuck off now guys
18:36 < TinKode> my words are just fucking around
18:36 < kanzure> string manipulation operations are things like appends, prepends, joins, splits, ligation, combination, inversions, etc.
18:36 < kanzure> http://diyhpl.us/~bryan/papers2/ai/The%20evolution%20of%20self-replicating%20computer%20organisms%20-%20A.%20N.%20Pargellis.pdf
18:37 < TinKode> once  you were able to make that in your water pot at home ill buy plane tickets to you at once
18:38 < cluckj> got half a billion years to wait around for it to happen?
18:38 < yashgaroth> and can my pot be the size of the earth
18:39 < TinKode> but anyway mind uploading is tricky
18:39 < TinKode> true mind hack
18:39 < TinKode> no need of o2
18:39 < TinKode> food
18:39 < TinKode> you live as an information
18:39 < cluckj> I do have something funky in my toilet that is relevant to this
18:39 < TinKode> computational information
18:40 < TinKode> but i doubt you will be the same as before
18:42 < kanzure> why would sameness matter?
18:42 < kanzure> i would take lots of dissimilarity over not having anything at all
18:42 < TinKode> what was again that russian project 2045
18:43 < cluckj> https://www.youtube.com/watch?v=VjbAgwdBaTI
18:43 < TinKode> with avatars
18:43 < TinKode> can't wait to see that shit
18:45 < kanzure> .title
18:45 < yoleaux> Blade Runner - I want more life... f..... - YouTube
18:46 < kanzure> anyway, 2045 is just a marketing stunt and a waste of time
18:46 < cluckj> oh nice it's fixed
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18:47 < nmz787_w> kanzure: 100mer link plz
18:47 < kanzure> nmz787_w: https://groups.google.com/d/msg/enzymaticsynthesis/uyZqtJO24RE/lApLb4JmCAAJ
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19:00 < kanzure> parahsailin was looking at "Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures"
19:00 < kanzure> .title http://www.nature.com/nature/journal/v453/n7194/full/nature06971.html
19:00 < yoleaux> Access : Mechanism of homologous recombination from the RecA|[ndash]|ssDNA/dsDNA structures : Nature
19:07 < kanzure> recA video thing (start at 15 sec) https://www.youtube.com/watch?v=BmSrjVLb94c&t=15s
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19:23 < kanzure> ensign: hi. sbp was saying something about you earlier today.
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19:54 < kanzure> "Gamma frequency entrainment attenuates amyloid load and modifies microglia" http://www.nature.com/nature/journal/v540/n7632/full/nature20587.html
19:55 < kanzure> "A high-throughput optomechanical retrieval method for sequence-verified clonal DNA" http://www.nature.com/articles/ncomms7073 https://twitter.com/erlichya/status/805786047623950336
19:55 < kanzure> "Writing DNA plays a significant role in the fields of synthetic biology, functional genomics and bioengineering. DNA clones on next-generation sequencing (NGS) platforms have the potential to be a rich and cost-effective source of sequence-verified DNAs as a precursor for DNA writing. However, it is still very challenging to retrieve target clonal DNA from high-density NGS platforms. Here we ...
19:55 < kanzure> ...propose an enabling technology called 'Sniper Cloning' that enables the precise mapping of target clone features on NGS platforms and non-contact rapid retrieval of targets for the full utilization of DNA clones. By merging the three cutting-edge technologies of NGS, DNA microarray and our pulse laser retrieval system, Sniper Cloning is a week-long process that produces 5,188 error-free sy...
19:56 < kanzure> ...nthetic DNAs in a single run of NGS with a single microarray DNA pool. We believe that this technology has potential as a universal tool for DNA writing in biological sciences."
19:56 < kanzure> "Designed proteins induce the formation of nanocage-containing extracellular vesicles" http://www.nature.com/nature/journal/v540/n7632/full/nature20607.html https://twitter.com/NatureBiotech/status/804324588184358912
19:57 < kanzure> "Here we describe the design of self-assembling protein nanocages that direct their own release from human cells inside small vesicles in a manner that resembles some viruses. We refer to these hybrid biomaterials as 'enveloped protein nanocages' (EPNs)."
19:58 < kanzure> .title https://www.youtube.com/watch?v=9_hJOcQu0hU
19:58 < yoleaux> An embolizing hydrogel that shifts its phase in response to mechanical shear forces - YouTube
19:59 < kanzure> "An injectable shear-thinning biomaterial for endovascular embolization" http://stm.sciencemag.org/content/8/365/365ra156
19:59 < kanzure> "Effective treatments for ruptured blood vessels must be rapidly deployed to promote hemostasis. Avery et al. formulated a gelatin and silicate nanoplatelet hydrogel material that occluded blood flow without requiring thrombus formation. When injected into arteries and veins in mice and pigs, the biomaterial occluded blood flow without evidence of fragmentation or displacement for up to 24 day...
19:59 < kanzure> ...s. Occluded vessels showed evidence of connective tissue replacing the biomaterial in the vessel lumen. Shear-thinning biomaterials represent promising alternatives for stable endovascular embolization."
20:00 < kanzure> i wonder why not just cauterize?
20:00 < kanzure> "To stop excessive bleeding or the flow of blood into an aneurysm, clinicians harness the same principle by forming artificial therapeutic emboli that can plug blood-carrying vessels. Using steerable catheters, they place tiny soft-metal coils or liquid embolic agents ("glues") into the affected artery to block the passage of blood"
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23:44 < fenn> maaku: pebble the smartwatch company went out of business
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--- Log closed Thu Dec 08 00:00:32 2016