--- Log opened Sat Feb 11 00:00:30 2017
00:07 < JayDugger> Yes, avoid Kress's Beggars in Spain.
00:10 < JayDugger> Nobody knows about Gene Wolfe because they lack hyperthymesia, or more accurately, the ability to fool researchers into it by keeping a mental perpetual calendar.
00:27 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection]
00:33 -!- esmerelda [~mabel@c-73-97-193-100.hsd1.wa.comcast.net] has joined ##hplusroadmap
00:49 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 245 seconds]
01:03 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
01:18 -!- augur [~augur@2601:645:8300:2b03:e879:c413:10e1:174e] has joined ##hplusroadmap
01:40 -!- jenelizabeth [~jenelizab@cpc76810-brmb10-2-0-cust4.1-3.cable.virginm.net] has quit [Ping timeout: 255 seconds]
01:59 -!- Gurkenglas__ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap
02:09 -!- ebowden_ [~ebowden@2001:8003:103c:ee00:ccde:5f6:7b13:156e] has joined ##hplusroadmap
02:09 -!- ebowden_ [~ebowden@2001:8003:103c:ee00:ccde:5f6:7b13:156e] has quit [Changing host]
02:09 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
02:09 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
02:15 -!- ebowden [~ebowden@1.152.97.78] has joined ##hplusroadmap
02:15 -!- ebowden [~ebowden@1.152.97.78] has quit [Changing host]
02:15 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
02:17 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
02:39 -!- augur [~augur@2601:645:8300:2b03:e879:c413:10e1:174e] has quit [Remote host closed the connection]
02:43 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
02:47 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Remote host closed the connection]
02:50 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
03:15 -!- esmerelda [~mabel@c-73-97-193-100.hsd1.wa.comcast.net] has quit [Ping timeout: 240 seconds]
03:37 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 245 seconds]
03:55 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
04:01 -!- nnnn20431 [~nnnn20430@plfgr.eu.org] has quit [Remote host closed the connection]
04:28 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds]
04:34 < kanzure> okay.
04:36 -!- jenelizabeth [~jenelizab@cpc76810-brmb10-2-0-cust4.1-3.cable.virginm.net] has joined ##hplusroadmap
04:41 < kanzure> "Software engineering at Google" https://arxiv.org/pdf/1702.01715.pdf
04:41 -!- Gurkenglas__ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds]
04:44 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
04:56 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection]
04:57 -!- ebowden [~ebowden@1.152.97.78] has joined ##hplusroadmap
04:57 -!- ebowden [~ebowden@1.152.97.78] has quit [Changing host]
04:57 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
05:01 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-obuznndneshkexfj] has joined ##hplusroadmap
05:01 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
05:31 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
05:35 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
06:51 -!- Gurkenglas__ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap
07:31 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has joined ##hplusroadmap
07:31 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has quit [Changing host]
07:31 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
07:32 < pasky> I have heard that the times of 20% time are long past in google?
07:32 < kanzure> i wouldn't know
07:36 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
07:38 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap
07:41 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap
08:00 -!- jenelizabeth [~jenelizab@cpc76810-brmb10-2-0-cust4.1-3.cable.virginm.net] has quit [Read error: No route to host]
08:00 -!- jenelizabeth [~jenelizab@cpc76810-brmb10-2-0-cust4.1-3.cable.virginm.net] has joined ##hplusroadmap
08:19 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds]
08:25 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
08:30 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
08:34 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
08:41 -!- BobaMa [bobama@kapsi.fi] has quit [Ping timeout: 240 seconds]
08:53 < archels> kanzure: met Aviv Bergman yesterday, incredibly nice fellow, very well-versed when it comes to aging research
08:53 < kanzure> what's the scoop
08:54 < archels> he shares the view that aging is a disease, but disagrees strongly with De Grey in that "garbage cleanup" is really going to effect anything; instead he believes aging is pretty hard-wired in the genetic code, and hence we should simply reprogram that
08:55 < archels> the argument he made against SENS was: honeybees
08:55 < archels> queen and workers share same DNA and everything, but workerbees live for four weeks at most, the queen can live up to 30 years
08:56 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap
08:57 < archels> this is, annoyingly, undated  http://thesciencenetwork.org/programs/diet-aging-and-metabolism/aviv-bergman
08:59 < kanzure> huh? "expression matters!" isn't a useful observation about bees...
09:00 < archels> the way I understood is that from this example, you can infer that death (at least in worker bees) is programmed
09:10 < kanzure> any particular epigenetic regulators that he is interested in?
09:14 < archels> we didn't get into that much technical detail; at any rate, I believe he's more interested in the principles than in the nitty-gritty
09:16 < kanzure> non-detail :(
09:18 -!- jcluck is now known as cluckj
09:39 < archels> .title http://www.pnas.org/content/99/16/10528.long
09:39 < yoleaux> Waddington's canalization revisited: Developmental stability and evolution
09:39 < archels> .title http://www.nature.com/nature/journal/v424/n6948/abs/nature01765.html
09:39 < yoleaux> Evolutionary capacitance as a general feature of complex gene networks : Abstract : Nature
09:47 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving]
10:15 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
10:19 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
10:24 -!- augur [~augur@2601:645:8300:2b03:8835:ce3b:c0f8:2c44] has joined ##hplusroadmap
10:32 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
10:41 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds]
10:44 < kanzure> https://www.christian-schneider.net/CrossSiteWebSocketHijacking.html
11:04 -!- lastfuture [~Peter@2a02:8071:b287:ec00:897e:686b:4a77:5e66] has joined ##hplusroadmap
11:09 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has joined ##hplusroadmap
11:09 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has quit [Changing host]
11:09 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
11:14 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
11:23 -!- urchin_ [~urchin@185.10.40.250] has joined ##hplusroadmap
11:26 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap
11:27 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 260 seconds]
11:29 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 245 seconds]
12:08 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Quit: Leaving.]
12:08 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap
12:37 -!- Gurkenglas__ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds]
12:55 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has joined ##hplusroadmap
12:55 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has quit [Changing host]
12:55 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
12:59 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
13:01 -!- lastfuture [~Peter@2a02:8071:b287:ec00:897e:686b:4a77:5e66] has quit [Quit: Be back later ...]
13:08 -!- sandeepkr [~Sandeepkr@103.49.155.114] has joined ##hplusroadmap
13:22 -!- augur [~augur@2601:645:8300:2b03:8835:ce3b:c0f8:2c44] has quit [Remote host closed the connection]
13:41 -!- sandeepkr [~Sandeepkr@103.49.155.114] has quit [Quit: Leaving]
13:49 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has joined ##hplusroadmap
13:49 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has quit [Changing host]
13:49 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
13:54 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
13:56 < kanzure> hmph
14:02 -!- lastfuture [~Peter@2a02:8071:b287:ec00:5467:12b0:d34a:220b] has joined ##hplusroadmap
14:06 -!- lastfuture [~Peter@2a02:8071:b287:ec00:5467:12b0:d34a:220b] has quit [Ping timeout: 255 seconds]
14:10 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
14:11 -!- nmz787_w [~ntmccork@134.134.139.76] has quit [Ping timeout: 240 seconds]
14:38 < kanzure> http://www.nature.com/news/climate-scientists-ponder-spraying-diamond-dust-in-the-sky-to-cool-planet-1.18634
14:43 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving]
14:47 < kanzure> not a very good page, hrm
15:02 -!- lastfuture [~Peter@2a02:8071:b287:ec00:dff:12d:bd35:8ae7] has joined ##hplusroadmap
15:05 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:24db:9505:39f5:9ed0] has joined ##hplusroadmap
15:07 -!- jenelizabeth [~jenelizab@cpc76810-brmb10-2-0-cust4.1-3.cable.virginm.net] has quit [Ping timeout: 255 seconds]
15:07 -!- lastfuture [~Peter@2a02:8071:b287:ec00:dff:12d:bd35:8ae7] has quit [Ping timeout: 255 seconds]
15:12 < kanzure> we should have blood replacements specific to brain function or modes
15:35 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has joined ##hplusroadmap
15:35 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has quit [Changing host]
15:35 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
15:39 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds]
15:47 -!- drewbot [~cinch@ec2-54-163-120-226.compute-1.amazonaws.com] has quit [Remote host closed the connection]
15:48 -!- drewbot [~cinch@ec2-54-90-216-155.compute-1.amazonaws.com] has joined ##hplusroadmap
15:58 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has joined ##hplusroadmap
15:58 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has quit [Changing host]
15:58 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
15:59 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection]
15:59 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
16:00 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection]
16:00 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has joined ##hplusroadmap
16:00 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has quit [Changing host]
16:00 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
16:03 -!- lastfuture [~Peter@2a02:8071:b287:ec00:905c:6e9:8c6d:58ee] has joined ##hplusroadmap
16:09 -!- lastfuture [~Peter@2a02:8071:b287:ec00:905c:6e9:8c6d:58ee] has quit [Ping timeout: 255 seconds]
16:11 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Quit: Leaving]
16:16 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:dc63:ae1f:988:67c5] has joined ##hplusroadmap
16:36 < kanzure> bloort
16:57 < kanzure> some sort of group doing open-source hardware for electrophysiology stuff http://www.open-ephys.org/
16:58 -!- pent [~pent@138.197.129.246] has quit [Read error: Connection reset by peer]
17:00 -!- pent [~pent@138.197.129.246] has joined ##hplusroadmap
17:00 < kanzure> "Homer1a drives homeostatic scaling-down of excitatory synapses during sleep" http://science.sciencemag.org/content/355/6324/511
17:01 < kanzure> "Diering et al. found that synapses undergo changes in synaptic glutamate receptors during the sleep-wake cycle, driven by the immediate early gene Homer1a. In awake animals, Homer1a accumulates in neurons but is excluded from synapses by high levels of noradrenaline. At the onset of sleep, noradrenaline levels decline, allowing Homer1a to move to excitatory synapses and drive synapse weakening."
17:01 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap
17:02 < kanzure> .tw https://twitter.com/CPW_Plymouth/status/825037459583021057
17:02 < yoleaux> 34th Microelectrode Techniques for Cell Physiology Workshop Plymouth UK Aug/Sept 2017 Apply: 31/03/2017 https://www.mba.ac.uk/microelectrode-techniques-for-cell-physiology/ ... Please RT https://pbs.twimg.com/media/C3MfKtrW8AEZtTD.jpg (@CPW_Plymouth)
17:04 < kanzure> how the hell is there enough content for 34 different conferences about microelectrode techniques
17:04 -!- lastfuture [~Peter@2a02:8071:b287:ec00:2128:1929:1339:49b3] has joined ##hplusroadmap
17:09 -!- lastfuture [~Peter@2a02:8071:b287:ec00:2128:1929:1339:49b3] has quit [Ping timeout: 255 seconds]
17:14 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-obuznndneshkexfj] has quit [Quit: Connection closed for inactivity]
17:18 -!- cluckj [~cluckj@pool-173-49-237-221.phlapa.fios.verizon.net] has quit [Ping timeout: 255 seconds]
17:18 < streety> It's a workshop, there have been trainees beginning to use microelectrode techniques for 34 years
17:23 -!- FiveBroDeepBook [~gk.1wm.su@2606:f180:1:2ea:2ea:af60:f0b8:8f26] has joined ##hplusroadmap
17:23 -!- FiveBroDeepBook [~gk.1wm.su@2606:f180:1:2ea:2ea:af60:f0b8:8f26] has left ##hplusroadmap []
17:39 < kanzure> hm okay
17:43 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Read error: Connection reset by peer]
17:44 -!- Cory [~Cory@unaffiliated/cory] has quit [Read error: No route to host]
17:49 -!- Cory [~Cory@unaffiliated/cory] has joined ##hplusroadmap
17:52 -!- dequ_ [christy@taurine.csclub.uwaterloo.ca] has quit [Ping timeout: 240 seconds]
17:52 -!- dequ [christy@taurine.csclub.uwaterloo.ca] has joined ##hplusroadmap
18:05 -!- lastfuture [~Peter@HSI-KBW-46-223-1-50.hsi.kabel-badenwuerttemberg.de] has joined ##hplusroadmap
18:10 -!- lastfuture [~Peter@HSI-KBW-46-223-1-50.hsi.kabel-badenwuerttemberg.de] has quit [Ping timeout: 240 seconds]
18:27 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap
18:28 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 240 seconds]
19:06 -!- lastfuture [~Peter@2a02:8071:b287:ec00:d16b:31a1:927f:9ed2] has joined ##hplusroadmap
19:11 -!- lastfuture [~Peter@2a02:8071:b287:ec00:d16b:31a1:927f:9ed2] has quit [Ping timeout: 255 seconds]
19:22 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 255 seconds]
19:47 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap
19:47 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 255 seconds]
19:49 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection]
19:49 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has joined ##hplusroadmap
19:49 -!- ebowden [~ebowden@2001:8003:103c:ee00:2162:738a:19df:d70e] has quit [Changing host]
19:49 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap
20:07 -!- lastfuture [~Peter@2a02:8071:b287:ec00:5542:5609:332b:c4e9] has joined ##hplusroadmap
20:11 -!- lastfuture [~Peter@2a02:8071:b287:ec00:5542:5609:332b:c4e9] has quit [Ping timeout: 255 seconds]
20:19 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap
21:07 -!- lastfuture [~Peter@2a02:8071:b2c0:c100:d2b:1dd4:1e4a:99fd] has joined ##hplusroadmap
21:12 -!- lastfuture [~Peter@2a02:8071:b2c0:c100:d2b:1dd4:1e4a:99fd] has quit [Ping timeout: 255 seconds]
22:05 < maaku> pasky: 20% time at G is long gone
22:08 -!- lastfuture [~Peter@HSI-KBW-46-223-1-54.hsi.kabel-badenwuerttemberg.de] has joined ##hplusroadmap
22:13 -!- lastfuture [~Peter@HSI-KBW-46-223-1-54.hsi.kabel-badenwuerttemberg.de] has quit [Ping timeout: 260 seconds]
22:50 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:dc63:ae1f:988:67c5] has quit [Quit: Leaving]
23:09 -!- lastfuture [~Peter@2a02:8071:b2c0:c100:35a3:877c:8391:1ca1] has joined ##hplusroadmap
23:10 -!- TinKode [~TinKode@unaffiliated/tinkode] has joined ##hplusroadmap
23:12 -!- sandeepkr [~Sandeepkr@103.49.155.114] has joined ##hplusroadmap
23:14 -!- lastfuture [~Peter@2a02:8071:b2c0:c100:35a3:877c:8391:1ca1] has quit [Ping timeout: 255 seconds]
23:19 -!- poohbear [~poohbear@unaffiliated/tigger] has quit [Quit: ZNC - http://znc.in]
23:27 -!- Gurkenglas__ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap
23:42 -!- sandeepkr [~Sandeepkr@103.49.155.114] has quit [Remote host closed the connection]
23:48 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection]
23:50 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 276 seconds]
--- Log closed Sun Feb 12 00:00:31 2017