--- Log opened Fri Mar 03 00:00:48 2017
00:03 -!- Gurkenglas [~Gurkengla@dslb-178-000-179-165.178.000.pools.vodafone-ip.de] has joined ##hplusroadmap
00:14 -!- redlegion[m] [redlegionm@gateway/shell/matrix.org/x-dwekumguzpstrfji] has quit [Write error: Connection reset by peer]
00:15 -!- TinKode [~TinKode@unaffiliated/tinkode] has quit [Quit: Practicing escapism.]
00:16 -!- Gurkenglas [~Gurkengla@dslb-178-000-179-165.178.000.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds]
00:20 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds]
00:33 -!- redlegion[m] [redlegionm@gateway/shell/matrix.org/x-dgjqqnnwiyvuswtm] has joined ##hplusroadmap
00:35 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 255 seconds]
00:38 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
00:47 -!- esmerelda [~mabel@2601:602:9603:a3f8:626d:c7ff:fe5f:86c7] has joined ##hplusroadmap
00:47 -!- esmerelda [~mabel@2601:602:9603:a3f8:626d:c7ff:fe5f:86c7] has quit [Changing host]
00:47 -!- esmerelda [~mabel@unaffiliated/jacco] has joined ##hplusroadmap
00:47 -!- esmerelda is now known as mabel
01:38 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection]
01:51 -!- abetusk [~abe@68.175.143.22] has quit [Ping timeout: 246 seconds]
01:55 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
02:04 -!- abetusk [~abe@68.175.143.22] has joined ##hplusroadmap
02:04 -!- abetusk is now known as Guest33321
02:39 -!- augur [~augur@2602:304:cdac:e260:bd34:b5c2:a12b:f231] has joined ##hplusroadmap
02:40 -!- augur [~augur@2602:304:cdac:e260:bd34:b5c2:a12b:f231] has quit [Remote host closed the connection]
02:49 -!- augur [~augur@2602:304:cdac:e260:bd34:b5c2:a12b:f231] has joined ##hplusroadmap
02:54 < streety> can you expand on that, what is the alternative? How can you hope to maximise progress without at least considering the risks involved in different approaches?
02:57 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap
03:06 -!- augur [~augur@2602:304:cdac:e260:bd34:b5c2:a12b:f231] has quit [Remote host closed the connection]
03:06 -!- augur [~augur@2602:304:cdac:e260:bd34:b5c2:a12b:f231] has joined ##hplusroadmap
03:29 -!- augur [~augur@2602:304:cdac:e260:bd34:b5c2:a12b:f231] has quit [Remote host closed the connection]
03:32 < kanzure> streety: people who believe in risk are often terrible, horrible people that don't do actual work
03:33 < kanzure> here is some alternative manifesto stuff http://lists.extropy.org/pipermail/extropy-chat/2004-May/006399.html
03:44 -!- CRM114 [~urchin@unaffiliated/urchin] has joined ##hplusroadmap
03:46 -!- mabel [~mabel@unaffiliated/jacco] has quit [Ping timeout: 240 seconds]
03:52 < kanzure> https://xkcd.com/1805/
03:53 < kanzure> maybe needs to be more militant i guess, to be a manifesto
04:02 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 256 seconds]
04:22 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
05:56 -!- bsm1175322 [~mcelrath@135.84.167.210] has quit [Ping timeout: 256 seconds]
06:15 -!- Gurkenglas [~Gurkengla@dslb-178-000-179-165.178.000.pools.vodafone-ip.de] has joined ##hplusroadmap
06:50 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds]
07:09 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
07:42 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap
07:45 -!- bsm1175322 [~mcelrath@135.84.167.210] has joined ##hplusroadmap
08:19 -!- augur [~augur@2602:304:cdac:e260:bd34:b5c2:a12b:f231] has joined ##hplusroadmap
08:24 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 268 seconds]
08:37 -!- augur [~augur@2602:304:cdac:e260:bd34:b5c2:a12b:f231] has quit [Ping timeout: 246 seconds]
08:41 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving]
08:43 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
08:47 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
08:56 < kanzure> https://primitivetechnology.wordpress.com/2016/07/29/forge-blower/
09:10 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap
09:14 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 246 seconds]
09:15 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection]
09:19 -!- bsm1175322 [~mcelrath@135.84.167.210] has quit [Remote host closed the connection]
09:26 -!- bsm1175322 [~mcelrath@135.84.167.210] has joined ##hplusroadmap
09:33 -!- Burn_ [~Burn@pool-108-56-208-224.washdc.fios.verizon.net] has joined ##hplusroadmap
09:35 -!- thxffo [smdikus@ircbouncehouse.com] has quit [Ping timeout: 240 seconds]
09:36 -!- strages_ [sid11297@gateway/web/irccloud.com/x-cqvuuriekkxprwhv] has joined ##hplusroadmap
09:38 -!- Taek42 [~quassel@2001:41d0:1:472e::] has joined ##hplusroadmap
09:38 -!- thxffo [smdikus@ircbouncehouse.com] has joined ##hplusroadmap
09:40 -!- maaku_ [~mark@173.234.25.100] has joined ##hplusroadmap
09:40 -!- liead [~adlai@unaffiliated/adlai] has joined ##hplusroadmap
09:41 -!- pent_ [~pent@138.197.129.246] has joined ##hplusroadmap
09:41 -!- jrayhawk_ [~jrayhawk@unaffiliated/jrayhawk] has joined ##hplusroadmap
09:41 -!- Jenda`_ [~bablbam@dekatron.hrach.eu] has joined ##hplusroadmap
09:41 -!- Dumuzi- [Dumuzi@Dont.Blink.PanicBNC.org] has joined ##hplusroadmap
09:43 -!- Netsplit *.net <-> *.split quits: Burnin8, strages, pent, Guest55178, nsh, Dumuzi, WizJin, adlai, ensign_, maaku,  (+4 more, use /NETSPLIT to show all of them)
09:44 -!- strages_ is now known as strages
09:44 -!- HEx [~HEx@hexwab.plus.com] has joined ##hplusroadmap
09:44 -!- kwgwk [~kwgwk@boole.london.hackspace.org.uk] has joined ##hplusroadmap
09:44 -!- HEx is now known as Guest78080
09:47 -!- ensign- [~ensign@2001:41d0:8:d711::1] has joined ##hplusroadmap
09:50 -!- nsh [~lol@wikipedia/nsh] has joined ##hplusroadmap
10:16 < kanzure> docker-compose to kubernetes migration tool thingy https://news.ycombinator.com/item?id=13783546
10:23 < kanzure> .title http://www.thespacereview.com/article/3181/1
10:23 < yoleaux> The Space Review: A radically easier path to space settlement
10:27 < kanzure> "Accelerating the domestication of new crops: feasibility and approaches" http://www.cell.com/trends/plant-science/abstract/S1360-1385(17)30015-8
10:27 < kanzure> "The domestication of new crops would promote agricultural diversity and could provide a solution to many of the problems associated with intensive agriculture. We suggest here that genome editing can be used as a new tool by breeders to accelerate the domestication of semi-domesticated or even wild plants, building a more varied foundation for the sustainable provision of food and fodder in t...
10:27 < kanzure> ...he future. We examine the feasibility of such plants from biological, social, ethical, economic, and legal perspectives."
10:27 < kanzure> (pop sci version: https://www.sciencedaily.com/releases/2017/03/170302133427.htm )
10:29 < kanzure> "Scalable design of paired CRISPR guide RNAs for genomic deletion" http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005341 ( https://phys.org/news/2017-03-genome-delete-button-dna.html )
10:30 < kanzure> "The Johnson lab recently created a tool based on CRISPR-Cas9, called "DECKO", which can be used to delete any desired piece of non-coding DNA. The unique advantage of DECKO is that it uses two individual sgRNAs, acting like two "molecular scissors" that snip out a piece of DNA. The approach was widely adopted, but as no software was available for designing the pairs of sgRNAs that are require...
10:30 < kanzure> ...d, designing deletion experiments was time-consuming. In response to this, the researchers in this study led by Carlos Pulido, created a software pipeline called CRISPETa, a flexible solution for designing CRISPR deletion experiments. The user tells CRISPETa what region they wish to delete, and the software returns a set of optimised pairs of sgRNAs."
10:34 -!- Guest78080 is now known as HEx1
11:16 < fenn> radiation mitigation for space settlement http://www.popularmechanics.com/space/moon-mars/a25493/magnetic-shield-mars-atmosphere/
11:16 < fenn> not only mars
11:17 < fenn> a superconducting coil 30 meters in diameter placed at mars-sun lagrange point
11:18 < fenn> the magnetic field creates a region shadowed from the solar wind
11:21 -!- Gurkenglas [~Gurkengla@dslb-178-000-179-165.178.000.pools.vodafone-ip.de] has quit [Ping timeout: 256 seconds]
11:30 -!- indiebio [~quassel@quassel.tumbleweed.org.za] has quit [Remote host closed the connection]
12:02 -!- indiebio [~quassel@quassel.tumbleweed.org.za] has joined ##hplusroadmap
12:03 < kanzure> "Alternative strategy for a safe rechargeable battery" http://pubs.rsc.org/en/Content/ArticleLanding/2017/EE/C6EE02888H
12:31 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
12:53 < kanzure> .title https://www.youtube.com/watch?v=luSqmjT6l00
12:53 < yoleaux> Tethon 3D Printing Ceramics Movie making mug v 3 - YouTube
12:55 < kanzure> .title https://www.youtube.com/watch?v=Lz88nsWL4kw
12:55 < yoleaux> Tomato sorting machine Sentinel II - TOMRA Sorting - YouTube
13:01 -!- nmz787_w [ntmccork@nat/intel/x-odwzsbnpxbbmxalh] has joined ##hplusroadmap
13:01 < nmz787_w> didn't we have a pexpect dev in here?
13:01 -!- nmz787_w [ntmccork@nat/intel/x-odwzsbnpxbbmxalh] has quit [Quit: Leaving.]
13:02 -!- nmz787_w [ntmccork@nat/intel/x-fcpnpkqipnhjgxtd] has joined ##hplusroadmap
13:02 -!- nmz787_w [ntmccork@nat/intel/x-fcpnpkqipnhjgxtd] has quit [Client Quit]
13:02 -!- nmz787_w [ntmccork@nat/intel/x-cxmbsfnzzypqtwma] has joined ##hplusroadmap
13:02 -!- nmz787_w [ntmccork@nat/intel/x-cxmbsfnzzypqtwma] has quit [Client Quit]
13:05 -!- nmz787_i [ntmccork@nat/intel/x-ncvasdravpmoxepu] has joined ##hplusroadmap
13:07 < kanzure> jquast
13:46 -!- Guest33321 is now known as abetusk
13:52 -!- computer_ [~computer@66.62.91.10] has quit [Quit: Leaving]
14:02 -!- Gurkenglas [~Gurkengla@dslb-178-000-179-165.178.000.pools.vodafone-ip.de] has joined ##hplusroadmap
14:10 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving]
14:15 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Quit: Leaving.]
14:56 -!- adnan [637f30d1@gateway/web/freenode/ip.99.127.48.209] has joined ##hplusroadmap
15:10 -!- adnan [637f30d1@gateway/web/freenode/ip.99.127.48.209] has quit [Quit: Page closed]
16:15 -!- WizJin [WizJin@gateway/shell/fnordserver.eu/x-npdbagfpgnchhquj] has joined ##hplusroadmap
16:33 -!- nmz787_i [ntmccork@nat/intel/x-ncvasdravpmoxepu] has quit [Remote host closed the connection]
17:02 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 240 seconds]
17:08 -!- nmz787_i [~ntmccork@134.134.139.82] has joined ##hplusroadmap
17:15 -!- eudoxia [~eudoxia@r186-49-245-242.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap
17:15 -!- eudoxia [~eudoxia@r186-49-245-242.dialup.adsl.anteldata.net.uy] has quit [Client Quit]
17:24 < nmz787_i> ugh
17:24 < nmz787_i> all day on pexpect detecting my shell's prompt
17:25 < kanzure> jquast is in #1984 on efnet i think
17:45 < nmz787_i> k, got on there
17:53 < kanzure> george church 23andme data https://my.pgp-hms.org/user_file/download/41
17:54 < kanzure> also 23andme data (in addition to genome of course) http://evidence.personalgenomes.org/genomes?display_genome_id=2e9b86bd7e2fb5b6770c2a9e9a336ba90677f83d&access_token=d6b5dbac12e8ab3afa1f25eef1ad0df5
18:05 < nmz787_i> kanzure: we also need to know his life history/biography though too... nature vs nurture, ya know
18:07 < kanzure> yes, yes... "any debilitating illnesses during childhood? on a scale from zero to john von neumann, please."
18:07 < nmz787_i> have you seen the movie 'lion'?
18:15 < kanzure> no
18:49 < nmz787_i> just found revision dates from 1992
18:58 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap
19:02 -!- Gurkenglas [~Gurkengla@dslb-178-000-179-165.178.000.pools.vodafone-ip.de] has quit [Ping timeout: 256 seconds]
19:56 < abetusk> https://my.pgp-hms.org/profile/hu43860C https://www.openhumans.org/member/geochurch/
20:00 < nmz787_i> yashgaroth: https://biotium.com/product/dnazure-blue-nucleic-acid-gel-stain/
20:00 < nmz787_i> got 'spammed' today
20:00 < nmz787_i> with that
20:06 < yashgaroth> oh weird, fills a niche I guess but SYBR stain is cheaper and doesn't need to develop
20:11 < yashgaroth> nmz787_: note that I don't know what that niche is, since you apparently can't even pre-cast gels with it
20:15 < nmz787_i> well it is certainly a thing
20:15 < nmz787_i> good to know about tools when problems arise
20:15 < nmz787_i> do you have to soak the gels after running?
20:15 < yashgaroth> perhaps some municipality has banned transilluminators, but for the price of that dye you could build/buy one
20:15 -!- Regex [~Cara@2601:1c0:8500:5edb:55dc:9021:bcb8:e743] has joined ##hplusroadmap
20:16 < yashgaroth> yeah gotta soak 'em with that stuff
20:16 < nmz787_i> or does the dye run with the wells?
20:16 < nmz787_i> oh, that isn't so bad
20:16 < nmz787_i> I mean, I did that in school
20:16 -!- Regex [~Cara@2601:1c0:8500:5edb:55dc:9021:bcb8:e743] has quit [Read error: Connection reset by peer]
20:16 < yashgaroth> yeah it's fine, just adds even more time to the development
20:16 -!- Regex [~Cara@2601:1c0:8500:5edb:55dc:9021:bcb8:e743] has joined ##hplusroadmap
20:26 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 264 seconds]
20:33 < kanzure> yashgaroth: have you found where the proposals get posted?
20:33 < kanzure> also nmz787_i was curious about the contents of your proposal, he might appreciate a copy
20:33 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap
20:36 < yashgaroth> no joy on the postings, will ask when they get back to me about presentations; I'll send the proposals to him
20:39 < nmz787_i> you might end up with another hotel-room-mate depending on how this goes
20:39 < nmz787_i> I think I can actually try the high-voltage stuff of this electroporator this weekend
20:39 < nmz787_i> heck, maybe tonight
20:39 < yashgaroth> dibs on not sleeping on pillows in the bathtub
20:40 < nmz787_i> I still don't know if I'm seeing totally glitch-free behavior from the timers, or if it is noise from the first PWM turning on or something... but I think it will be OK for now
20:40 < nmz787_i> working on setting them all up without micropython's help
20:40 < nmz787_i> directly writing their registers
20:41 < nmz787_i> I think I got the timers configured last night, but now I have to setup the GPIO and MUX it to the timer event or something
20:42 -!- nmz787_i [~ntmccork@134.134.139.82] has left ##hplusroadmap []
22:04 < rk[ghost]>  /window 10
22:05 < rk[ghost]> doh..
22:33 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
23:15 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving]
23:20 -!- drewbot [~cinch@ec2-54-211-183-198.compute-1.amazonaws.com] has quit [Remote host closed the connection]
23:21 -!- drewbot [~cinch@ec2-54-80-105-200.compute-1.amazonaws.com] has joined ##hplusroadmap
23:49 -!- esmerelda [~mabel@c-73-97-193-100.hsd1.wa.comcast.net] has joined ##hplusroadmap
23:49 -!- esmerelda [~mabel@c-73-97-193-100.hsd1.wa.comcast.net] has quit [Changing host]
23:49 -!- esmerelda [~mabel@unaffiliated/jacco] has joined ##hplusroadmap
23:50 -!- vicarion [~net@d49-188-0-106.sun1.vic.optusnet.com.au] has joined ##hplusroadmap
23:55 -!- vicarion [~net@d49-188-0-106.sun1.vic.optusnet.com.au] has quit [Ping timeout: 268 seconds]
--- Log closed Sat Mar 04 00:00:49 2017