--- Log opened Sat Mar 25 00:00:08 2017
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02:51 < archels> that sucks
02:52 < archels> kanzure: where does Russell say that? (re BrainBackups)
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04:32 < archels> .title https://twitter.com/sadladbukharin/status/840591916773363713
04:32 < yoleaux> sadbukharin auf Twitter: ""how many levels of tech dystopia you on" "like reactionary cyber personality interrogating an AI over it's deep state connections" https://t.co/BHiKKunxIz"
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06:03 < kanzure> archels: it was facebook :(
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10:53 < kanzure> .tw https://twitter.com/karpathy/status/843887305731395584
10:53 < yoleaux> Excited to join the steering committee of Distill https://blog.ycombinator.com/distill-an-interactive-visual-journal-for-machine-learning-research/ 1) exposition is main focus, 2) articles use modern web technology (@karpathy)
10:55 < kanzure> "Experimental assessment of the safety and potential efficacy of high irradiance photostimulation of brain tissues" http://www.nature.com/articles/srep43997 https://twitter.com/JWietek/status/845309042025205760
10:55 < kanzure> "We studied the spatial distribution of light, potential damage, and non-physiological effects in vivo, in anesthetized rat brains, on large brain volumes, following repeated high irradiance photo-stimulation. We generated 2D irradiance and temperature increase surface maps based on recordings taken during optical stimulation using irradiance and temporal parameters representative of common op...
10:55 < kanzure> ...togenetics experiments. Irradiances of 100 to 600 mW/mm2 with 5 ms pulses at 20, 40, and 60 Hz were applied during 90 s. In vivo electrophysiological recordings and post-mortem histological analyses showed that high power light stimulation had no obvious phototoxic effects and did not trigger non-physiological functional activation. This study demonstrates the ability to illuminate cor...
10:55 < kanzure> ...tical layers to a depth of several millimeters using pulsed red light without detrimental thermal damages."
10:59 < kanzure> .title https://sfbay.craigslist.org/eby/sci/6032033117.html
10:59 < yoleaux> Biotech Start-Up Looking for the Ri(ck)(ta) Sanchez to my Rick Sanchez
11:00 < kanzure> an ad from the-odin
11:00 < kanzure> "In late 2014 I decided to make a DIY Bacterial genome engineering CRISPR kit(http://www.the-odin.com/diy-bacterial-gene-engineering-crispr-kit/) and raised ~$70k through crowdfunding. In 2015 we made around $200k and this year we are projected to make near $500k."
11:02 < kanzure> yashgaroth: you gonna take him up on that?
11:04 < yashgaroth> nnnope
11:11 < nmz787_> if only it was in my neighborhood, or if there was a hyperloop from here to oakland...
11:12 < nmz787_> I lack the PhD he seeks though
11:12 < nmz787_> maybe I could manage to get into Berkeley for a PhD there... and have 2 reasons to move there
11:12 < nmz787_> it is really, really urban, though
11:13 < nmz787_> I enjoy being outnumbered by ~8 to 1 by massive trees
11:14 < nmz787_> I do wonder about what it would take to get an 'intern'
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11:28 < andytoshi> kanzure: a friend of mine is asking about "henle loop lengths in nephron" .... specifically whether these seem to be affected in humans by ancestral climate
11:29 < andytoshi> are you aware of any studies about this?
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12:16 < kanzure> no?
12:17 < andytoshi> heh, kk
12:19 < andytoshi> it's not like anything we've ever talked about, but you've got a lot of esotoric knowledge
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12:29 < kanzure> sure, sure. just haven't heard of thta.
12:29 < kanzure> *that.
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15:31 < streety> it's not clear from that posting but I'm assuming the figures given are revenue. Or is it profit?
15:33 < streety> andytoshi: I work in the kidney field but haven't seen anything along those lines mentioned. Most of the serious structural studies are from back in the '70s and '80s. Potentially returning to interest with tissue clearing and 3D imaging but more mouse work so far
15:36 < kanzure> streety: still doing iDISCO things?
15:36 < kanzure> or on to a new technique?
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15:51 < streety> I actually haven't done any tissue clearing of any sort since last summer. The group I'm in doesn't have a strong imaging focus so I was dependent on collaborating with others. The couple of options I had were looking like they would require a major, largely unsupported, effort to getting working.
15:52 < streety> I moved on to projects that required less new tech.
15:52 < streety> Easier to keep the key parts within the group and keep momentum
15:56 < kanzure> did you see the two-antibody imaging system mentioned in here the other day?
15:56 < kanzure> "Rapid sequential in situ multiplexing with DNA-exchange-imaging" http://biorxiv.org/content/early/2017/03/20/112227
15:57 < kanzure> "Multiplexed confocal and super-resolution fluorescence imaging of cytoskeletal and neuronal synapse proteins" http://www.biorxiv.org/content/early/2017/02/25/111625
15:59 < streety> I missed that, I'll take a look, thanks
16:00 < kanzure> as for the-odin, i would guess revenue not profit
16:12 < streety> yeah, that was my interpretation as well. It's an interesting way of phrasing it though. I wonder how many people that can support the cost of living for in that area of the world
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19:04 < kanzure> random news article about that startup 'egenesis' for pig organ xenotransplantation stuff http://medcitynews.com/2017/03/egenesis-bets-crispr-domesticate-pig-organs-safer-xenotransplantation/
19:45 < kanzure> calcium carbonate geoengineering stuff for anti climate change http://geoengineering.environment.harvard.edu/
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22:14 < kanzure> randal koene in the news i guess https://www.theguardian.com/science/2017/mar/25/animal-life-is-over-machine-life-has-begun-road-to-immortality
22:15 < kanzure> bryan johnson stuff http://osfund.co/
22:17 < kanzure> http://bryanjohnson.co/
22:17 < kanzure> oh right, he is also doing http://kernel.co/
22:48 < kanzure> which is ted berger's hippocampus implants
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--- Log closed Sun Mar 26 00:00:08 2017