--- Log opened Wed Mar 29 00:00:11 2017 00:15 -!- sbodin [~sbodin@91.226.141.245] has joined ##hplusroadmap 00:25 -!- sbodin [~sbodin@91.226.141.245] has quit [Ping timeout: 246 seconds] 00:30 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 256 seconds] 00:36 -!- augur [~augur@80.234.142.240] has joined ##hplusroadmap 00:39 -!- ExeciN [ExeciN@bnc.stormbit.net] has quit [Excess Flood] 00:42 -!- ExeciN [ExeciN@bnc.stormbit.net] has joined ##hplusroadmap 00:43 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 01:44 -!- augur [~augur@80.234.142.240] has quit [Remote host closed the connection] 02:26 -!- bluebear_ [~dluhos@80.95.97.194] has joined ##hplusroadmap 02:44 -!- augur [~augur@62.252.147.50] has joined ##hplusroadmap 02:46 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: sleep] 02:50 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 246 seconds] 03:03 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 03:32 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 256 seconds] 03:45 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 03:58 -!- augur [~augur@62.252.147.50] has quit [Remote host closed the connection] 04:01 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 258 seconds] 04:02 -!- drewbot [~cinch@ec2-23-20-144-148.compute-1.amazonaws.com] has quit [Remote host closed the connection] 04:03 -!- drewbot [~cinch@54.227.16.11] has joined ##hplusroadmap 04:08 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 04:20 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 04:35 < andytoshi> lol "are you experiencing the anesthetics" 04:35 < andytoshi> obviously not regardless of any robot shit 04:38 -!- sachy [~sachy@nat.brmlab.cz] has quit [Ping timeout: 256 seconds] 04:38 < andytoshi> i think the questions linked to probably haven't taken up very much of anybody's time who could've been doing WBE or useful AI work 04:39 < andytoshi> i have a bunch related to what happens if you encrypt a WBE in various ways but i think the answer to all of them is "wait and see" 04:46 -!- sachy [~sachy@nat.brmlab.cz] has joined ##hplusroadmap 05:16 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-tvedlgyyhljpmodk] has joined ##hplusroadmap 05:17 -!- urchin_ [~urchin@dsl-89-17-8-82.dsl.h-1.hr] has quit [Changing host] 05:17 -!- urchin_ [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 05:17 -!- urchin_ is now known as Urchin 05:22 < archels> pretty good resource on quaternions http://www.turingbirds.com/_lib/math/Andrew_J._Hanson_Visualizing_Quaternions.pdf 05:33 -!- CRM114 [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 05:44 -!- augur [~augur@dynamic-earth.fluency.net.uk] has joined ##hplusroadmap 06:27 < JayDugger> Good morning. 06:27 -!- c0rw1n_ [~c0rw1n@2a00:23c5:a81:ba00:a0c2:a736:122c:dff2] has quit [Ping timeout: 264 seconds] 06:28 -!- augur [~augur@dynamic-earth.fluency.net.uk] has quit [Remote host closed the connection] 06:32 -!- augur [~augur@dynamic-earth.fluency.net.uk] has joined ##hplusroadmap 06:37 -!- augur [~augur@dynamic-earth.fluency.net.uk] has quit [Ping timeout: 268 seconds] 06:53 < kanzure> welllll they might not be working on whole brain emulation, but what about me? 06:56 -!- jtimon [~quassel@70.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 06:59 -!- urchin_ [~urchin@dsl-89-17-5-67.dsl.h-1.hr] has joined ##hplusroadmap 07:00 < gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=c7eee8df Bryan Bishop: another sharding link >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/sharding-the-blockchain/ 07:02 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 258 seconds] 07:02 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Ping timeout: 260 seconds] 07:06 < kanzure> tsk tsk http://news.berkeley.edu/2017/03/28/european-patent-office-to-grant-uc-a-broad-patent-on-crispr-cas9/ 07:09 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 07:15 < kanzure> some hashcash background https://www.reddit.com/r/Bitcoin/comments/62500v/bu_supporter_tells_adam_back_he_should_read_the/dfk4p9q/ 07:16 -!- augur [~augur@dynamic-earth.fluency.net.uk] has joined ##hplusroadmap 07:21 -!- augur [~augur@dynamic-earth.fluency.net.uk] has quit [Ping timeout: 256 seconds] 07:25 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 07:50 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 08:04 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 08:05 < kanzure> if you were able to graffiti anything on to the walls and floors of the defense distributed factory, what would it be? 08:16 < kanzure> .title http://nature.com/articles/doi:10.1038/nbt.3805 08:16 < yoleaux> Large-scale design of robust genetic circuits with multiple inputs and outputs for mammalian cells : Nature Biotechnology : Nature Research 08:16 < kanzure> lotta interesting recombinase stuff in there 08:28 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Quit: Leaving.] 08:33 -!- nmz787_i [~ntmccork@134.134.139.78] has joined ##hplusroadmap 08:41 < TMA> kanzure: something like this: http://www.morethanmaths.com/wp-content/gallery/illusions2/black-white-tiles.gif 08:42 < nmz787_i> that works in all directions! 08:43 < kanzure> i was thinking something more like https://www.blogcdn.com/www.engadget.com/media/2011/05/pirate-bay-2011-05-12.jpg 09:18 < kanzure> .title https://news.ycombinator.com/item?id=13985902 09:18 < yoleaux> Bigger brains are not always better | Hacker News 09:18 < kanzure> ( https://www.scientificamerican.com/article/the-genius-of-pinheads-when-little-brains-rule/ ) 09:18 < kanzure> womp womp "When I got to that part of the article, it just seemed to me he was expecting the same CPU to perform better at a specific, more-or-less optimized task just because it was larger, regardless of architecture or the amount of components within the CPU." 09:29 < kanzure> asheville diybio wiki has been spammed to death :| 09:46 -!- augur [~augur@176-35-60-83.xdsl.murphx.net] has joined ##hplusroadmap 09:49 -!- Urchin[emacs] [~user@unaffiliated/urchin] has joined ##hplusroadmap 09:57 -!- augur [~augur@176-35-60-83.xdsl.murphx.net] has quit [Remote host closed the connection] 10:14 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 10:16 < kanzure> .tw https://twitter.com/TheCryptoShow/status/846385223176798210 10:16 < yoleaux> The Crypto Show with Randolph Hencken & Joe Quirk on Seasteading https://letstalkbitcoin.com/blog/post/the-crypto-show-with-randolph-hencken-joe-quirk-on-seasteading @joequirkexults @Seasteading @randolphhencken (@TheCryptoShow) 10:16 < kanzure> .tw https://twitter.com/kenshishido/status/843665584768323584 10:16 < yoleaux> Typical Bitcoin company office in Texas, USA. @TheCryptoShow https://pbs.twimg.com/media/C7VNV7AV0AAcuhF.jpg (@kenshishido) 10:17 < kanzure> cc jrayhawk 10:17 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 10:19 < kanzure> .tw https://twitter.com/kanzure/status/847135284919709698 10:19 < yoleaux> I'll be on @TheCryptoShow 89.1 FM in Austin, Texas at 8pm this evening. (@kanzure) 10:20 -!- Guest64522 [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 246 seconds] 10:27 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 10:28 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 10:31 < kanzure> .wik defense distributed 10:31 < yoleaux> "Defense Distributed is an online, open-source organization that designs firearms, or "wiki weapons", that may be downloaded from the Internet and "printed" with a 3D printer. Among the organization's goals is to develop and freely publish firearms-related design schematics that can be downloaded and reproduced by anyone with a 3D printer." -- https://en.wikipedia.org/wiki/Defense_distributed 10:33 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 268 seconds] 10:38 < nmz787_i> hmm, found a guy offering phd student position, focusing on DNA synthesis 10:38 < nmz787_i> but he's in Ontario Canada :/ 10:40 < nmz787_i> and another in Michigan, eww 10:41 < nmz787_i> I guess that's slightly more interesting terrain than Ontario 10:41 < nmz787_i> I think 10:42 < nmz787_i> no, I guess not 10:43 < JayDugger> hmm...how long do you suppose before the audio appears on Soundcloud? 10:44 < nmz787_i> hmm, Kosuri has a lab at UCLA... that is better than middle-america 10:48 < kanzure> JayDugger: probably an hour after, is my guess 10:48 < kanzure> might be livestreamed on youtube 10:53 < JayDugger> Good, good, thanks. 10:54 < kanzure> https://media0.giphy.com/media/eHYazg6wGDqYE/200_s.gif 10:56 < JayDugger> Hey! My vitamin D deficiency isn't THAT bad. 10:57 -!- augur [~augur@176-35-60-83.xdsl.murphx.net] has joined ##hplusroadmap 10:59 < kanzure> nmz787_i: kosuri is really interested in hiring software people 11:00 < kanzure> nmz787_i: IMHO you should aim for church lab 11:00 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 11:00 < kanzure> i think i had a phone call with kosuri, i typed it out somewhere, ask me later for a copy 11:01 < kanzure> ok sent 11:04 < nmz787_i> reading 11:10 < kanzure> http://joshmitteldorf.scienceblog.com/2017/03/28/senolytics-against-aging-snapshot-of-a-fast-moving-field/ 11:12 -!- Gurkenglas_ [~Gurkengla@dslb-188-103-066-228.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 264 seconds] 11:13 < kanzure> .wik quercetin 11:13 < yoleaux> "Quercetin /'kw?:rs?t?n/ is a flavonol found in many fruits, vegetables, leaves, and grains. It can be used as an ingredient in supplements, beverages, or foods." -- https://en.wikipedia.org/wiki/Quercetin 11:24 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 11:27 < FourFire> kanzure, I've been told by Steve Hill that isoquercetin has superior bioaviliability 11:35 -!- nmz787_i [~ntmccork@134.134.139.78] has quit [Quit: Leaving.] 11:43 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 12:02 -!- augur [~augur@176-35-60-83.xdsl.murphx.net] has quit [Remote host closed the connection] 12:40 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 12:43 -!- bluebear_ [~dluhos@80.95.97.194] has quit [Quit: Leaving.] 12:54 -!- nmz787_i [~ntmccork@134.134.137.71] has joined ##hplusroadmap 12:59 -!- nmz787_i1 [~ntmccork@134.134.139.74] has joined ##hplusroadmap 13:00 -!- nmz787_i [~ntmccork@134.134.137.71] has quit [Ping timeout: 260 seconds] 13:12 -!- bruh21 [~brehBruh@2605:e000:1714:8105:9d6a:a574:981:83ef] has joined ##hplusroadmap 13:22 < kanzure> bruh21: hi. 13:22 < bruh21> hello 13:24 < kanzure> ted chiang in new yorker https://news.ycombinator.com/item?id=13989588 13:24 < kanzure> maybe he will get a second movie 14:48 < jrayhawk> kanzure: are the Harbor Freight moving blankets being used as sound isolation? 14:48 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 258 seconds] 14:53 -!- rancyd [stryfe@unaffiliated/rancyd] has quit [Ping timeout: 246 seconds] 14:56 -!- rancyd [stryfe@unaffiliated/rancyd] has joined ##hplusroadmap 15:14 < abetusk> http://www.prnewswire.com/news-releases/veritas-genetics-collaborates-with-dr-steven-narod-and-womens-college-hospital-to-launch-the-screen-project---a-population-based-brca-screening-initiative-across-canada-300430320.html 15:14 < abetusk> .title 15:14 < yoleaux> Veritas Genetics Collaborates with Dr. Steven Narod and Women's College Hospital to Launch The 15:15 < kanzure> which one was veritas, again. was this the cheapo exome sequencing one? 15:25 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds] 15:50 < kanzure> "Well for a game made by a man who wears a scary moon helmet and calls himself god, it sure came out alright." 16:50 < abetusk> Veritas offers $1k DTC whole genome sequencing 16:51 < abetusk> https://www.veritasgenetics.com/mygenome 17:16 -!- maaku [~mark@173.234.25.100] has quit [Quit: Lost terminal] 17:17 -!- nmz787_i1 [~ntmccork@134.134.139.74] has quit [Remote host closed the connection] 17:17 -!- maaku [~mark@173.234.25.100] has joined ##hplusroadmap 17:28 < streety> it was another company offering cheap exome sequencing 17:28 < streety> well, cheaper, veritas does do it but not at as attractive a price 17:29 < streety> I think https://genos.co/ was the cheap exome sequencing 17:52 -!- bruh21 [~brehBruh@2605:e000:1714:8105:9d6a:a574:981:83ef] has quit [Quit: Leaving] 18:01 < nmz787_> blaaaa 18:45 < nmz787_> "These soothing chemical patches alter your baby's DNA, while leaving the RNA untouched." 19:10 -!- Gurkenglas_ [~Gurkengla@dslb-188-103-066-228.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 19:19 < juri_> nmz787_: wow. pass along the stupid please. 19:43 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 19:44 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-tvedlgyyhljpmodk] has quit [Quit: Connection closed for inactivity] 20:58 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 20:59 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 246 seconds] 21:11 -!- esmerelda [~mabel@2601:602:9603:a3f8:65e5:be41:3c9c:c816] has joined ##hplusroadmap 21:11 -!- esmerelda [~mabel@2601:602:9603:a3f8:65e5:be41:3c9c:c816] has quit [Changing host] 21:11 -!- esmerelda [~mabel@unaffiliated/jacco] has joined ##hplusroadmap 21:22 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap 21:27 -!- Burnin8 [~Burn@pool-108-56-208-224.washdc.fios.verizon.net] has quit [Ping timeout: 264 seconds] 21:30 < kanzure> https://soundcloud.com/heryptohow/andrew-poelstra-bryan-bishop-and-brian-deery 21:36 -!- dustinm [~dustinm@68.ip-149-56-14.net] has quit [Quit: Leaving] 21:38 -!- dustinm [~dustinm@68.ip-149-56-14.net] has joined ##hplusroadmap 22:12 -!- jcluck [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has joined ##hplusroadmap 22:15 -!- cluckj [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has quit [Ping timeout: 260 seconds] 22:29 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 22:30 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection] 22:33 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 22:35 < entity8421[m]> whats the best longterm nootropic productivity and improving consciousness? semax, pramiracetam, fasoracetam maybe? 22:35 < entity8421[m]> *for 22:35 < entity8421[m]> and i forgot uridine 22:44 < kanzure> now who is going to type that up 22:45 -!- ebowden [~ebowden@1.136.96.7] has joined ##hplusroadmap 22:45 -!- ebowden [~ebowden@1.136.96.7] has quit [Changing host] 22:45 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 22:56 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] 23:05 -!- augur [~augur@195.11.164.221] has joined ##hplusroadmap 23:08 -!- augur [~augur@195.11.164.221] has quit [Remote host closed the connection] 23:22 -!- augur_ [~augur@195.11.164.221] has joined ##hplusroadmap 23:24 -!- augur_ [~augur@195.11.164.221] has quit [Read error: Connection reset by peer] 23:24 -!- augur_ [~augur@195.11.164.221] has joined ##hplusroadmap 23:28 -!- augur_ [~augur@195.11.164.221] has quit [Ping timeout: 240 seconds] 23:32 -!- thundara [~thundara@104.236.109.149] has quit [Ping timeout: 240 seconds] 23:32 -!- thundara [~thundara@104.236.109.149] has joined ##hplusroadmap 23:34 -!- Burninate [~Burn@pool-108-18-203-134.washdc.fios.verizon.net] has joined ##hplusroadmap 23:55 < poppingtonic> kanzure: I'm listening to The Crypto Show --- Log closed Thu Mar 30 00:00:12 2017