--- Log opened Fri Jun 02 00:00:11 2017
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05:11 < kanzure> "So far, 70 people have been treated, all of whom paid Ambrosia $8000 to be included in the study."
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07:27 < archels> http://naviauxlab.ucsd.edu/wp-content/uploads/2016/09/cell_danger_response.pdf
07:28 < kanzure> you are late to the party, check backlog
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07:35 < kanzure> more DPRK CNC propaganda during a birthday celebration of some kind https://www.youtube.com/watch?v=Yh0bwh6hXIc
07:41 < archels> ah, cheers
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09:28 < nmz787_i> beam source refill person said sometimes you can get double the manufacturer's quoted beam time... and he said run the one I've got til I know it's dying
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09:29 < chris_99> heh interesting
09:30 < chris_99> does the machine warn you if it gets low, is it just something you notice from the images
09:30 < chris_99> *or is it
09:31 < nmz787_i> not sure, was just wondering that myself
09:31 < nmz787_i> i was thinking maybe the beam current starts falling
09:31 < nmz787_i> or as you said, some random noise in the images
09:31 < chris_99> ah so it could have a warning circuit then maybe?
09:31 < nmz787_i> well, it has a picoammeter
09:31 < chris_99> oh interesting
09:32 < nmz787_i> since you can use a physical aperture to block the beam, to reduce current
09:32 < nmz787_i> not sure it would have a warning
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09:37 < nmz787_i> hrmmm, is there a biopython IRC room?
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09:39 < nmz787_i> I'm trying to use a sequence alignment tool to match 1000s of names that a series of tools has mangled.... I need to map the pre-mangled and post-mangled... and the biopython sequence alignment stuff is pretty tricky to tune parameters for
09:39 < nmz787_i> I'm not sure how to handle duplications and insertions
09:40 < nmz787_i> almost seems a regex might be better, but then I wouldn't get a score to sort 'best' hits with.... or ideally do some sort of outlier analysis to prune a bunch of bad scoring hits
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11:06 < streety> what are you using that mangled the names so badly? Is the rest of the output trustworthy? Would it not be better to fix the issue at the source?
11:06 < streety> fuzzywuzzy would be a potential alternative depending on exactly what you need
11:07 < nmz787_i> streety: haha, "some say I'm a dreamer, but I'm not the only one"
11:07 < nmz787_i> it /would/ seem correct to fix the issue at the source, leave some metadata of the original name
11:07 < nmz787_i> but no...
11:08 < nmz787_i> I work in a big hulking company with too much inertia to get something like that changed in any reasonable amount of time
11:09 < nmz787_i> I added another rule-based method of de-mangling... maybe that will at least reduce the amount of guess-matching it has to attempt with the bioinformatic tool
11:09 < nmz787_i> /me checking out fuzzywuzzy now
11:10 < nmz787_i> it indeed appears that adding another rule upped my 'direct hits' by ~10X
11:10 < streety> glorious inertia, good luck with it. sounds like an 'interesting' challenge
11:11 < streety> https://github.com/seatgeek/fuzzywuzzy implementations in various languages
11:13 < nmz787_i> hmm, yeah this looks like I can definitely give it a shot
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12:27 < superkuh> via hackernews, http://www.cell.com/cell/abstract/S0092-8674%2817%2930584-6
12:29 < superkuh> "Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields" Edward Boyden involved.
12:35 < superkuh> tldr; two pairs of electrodes with same polarity electrodes close to each other. The two groups operate at freq too high to trigger neural activity, 2 KHz and 2.01 KHz, but where the current flows in the brain overlap the superposition beats at 10 Hz and that can trigger 10 Hz spiking.
12:36 < archels> thx
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13:34 < nmz787_i> read that one via twitter earlier... or facebook maybe
13:34 < nmz787_i> unfortunately that was on another device and crossposting is not readily straightforward
13:46 < nmz787_i> I replied to GP-write survey saying to invite Marvin Caruthers and more chemists
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14:09 < kanzure> what is the targeting resolution of that electric current interference phase stuff?
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16:17 < nmz787_i> kanzure: Figure S4. seems the one you want to parse
16:27 < nmz787_i> and it seems (F) is the point you want: "(F) Percentage of c-fos  -positive cells within a DAPI-labeled cortical area (500 ?m x 500 ?m) underneath the electrode..."
16:27 < nmz787_i> but looking at their bar graph, it is annotated "n.s." which either means non-stimulated... or maybe idk non-significant??
16:28 < nmz787_i> then they have supplementary table 2, an Excel file
16:28 < nmz787_i> idk
16:31 < nmz787_i> yeah, idk... this paper seems a bit 'all over the place'... or maybe they were somehow only looking to induce longterm changes?
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21:04 < nmz787_i> .wik electron beam welding
21:04 < yoleaux> "Compare the main article "Elektronenstrahl-Materialbearbeitung" within the German Wikipedia." -- https://en.wikipedia.org/wiki/Electron_beam_welding
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21:09 < kanzure> "Discreet log contracts" https://adiabat.github.io/dlc.pdf
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--- Log closed Sat Jun 03 00:00:11 2017