--- Log opened Sat Jun 10 00:00:18 2017 00:11 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 00:12 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 00:27 -!- preview [~preview@118-92-220-128.dsl.dyn.ihug.co.nz] has quit [Read error: Connection reset by peer] 00:33 -!- preview [~preview@118-92-220-128.dsl.dyn.ihug.co.nz] has joined ##hplusroadmap 00:38 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 00:43 -!- jtimon [~quassel@117.29.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 00:47 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Remote host closed the connection] 01:24 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 01:35 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 01:35 < kanzure> you guys are so boring 01:39 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 01:47 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 01:47 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 01:47 -!- ebowden [~ebowden@2001:8003:1074:bc00:9d38:5d7b:ba20:a7b6] has joined ##hplusroadmap 01:47 -!- ebowden [~ebowden@2001:8003:1074:bc00:9d38:5d7b:ba20:a7b6] has quit [Changing host] 01:47 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 01:47 -!- jenelizabeth [~jenelizab@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 246 seconds] 01:52 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Ping timeout: 255 seconds] 02:24 -!- preview [~preview@118-92-220-128.dsl.dyn.ihug.co.nz] has quit [Remote host closed the connection] 02:25 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 02:27 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 02:32 -!- preview [~preview@118-92-220-128.dsl.dyn.ihug.co.nz] has joined ##hplusroadmap 02:41 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Read error: Connection reset by peer] 02:41 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 02:45 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 246 seconds] 03:11 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 03:18 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 03:22 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Ping timeout: 240 seconds] 03:35 -!- preview [~preview@118-92-220-128.dsl.dyn.ihug.co.nz] has quit [Remote host closed the connection] 03:40 -!- preview [~preview@2407:7000:842d:4078:ab39:1b65:59a7:cd65] has joined ##hplusroadmap 03:50 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 03:53 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 03:56 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 260 seconds] 04:09 -!- cluckj [~cluckj@pool-108-52-166-30.phlapa.fios.verizon.net] has quit [Ping timeout: 246 seconds] 04:13 -!- cluckj [~cluckj@pool-108-52-166-30.phlapa.fios.verizon.net] has joined ##hplusroadmap 04:34 -!- JenElizabeth [~Jen3@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 04:37 -!- Jen [~Jen3@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 240 seconds] 04:44 < JayDugger> Watch those comments, kanzure. I'll retire early, drive to your house, and camp out there with a sign reading "Why doesn't skdb make me a nuclear pulse rocket yet?" 04:48 -!- preview [~preview@2407:7000:842d:4078:ab39:1b65:59a7:cd65] has quit [Remote host closed the connection] 04:49 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 04:49 -!- preview [~preview@2407:7000:842d:4078:ab39:1b65:59a7:cd65] has joined ##hplusroadmap 04:53 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Ping timeout: 255 seconds] 04:54 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Quit: Leaving.] 04:54 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 04:58 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 05:03 < kanzure> that was always your department; you were going to contribute the code and hardware for that. 05:09 < JayDugger> Fair enough. Writing a bug report like that does count as the easy way out. 05:09 < JayDugger> May I at least launch from your yard? 05:16 < kanzure> wait, do i really seem like the type of person to own a yard? 05:17 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 05:19 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap 05:28 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 245 seconds] 05:29 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 05:30 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 05:34 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 05:38 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 05:41 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 05:47 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 240 seconds] 05:49 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 06:19 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 06:22 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 260 seconds] 06:24 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 06:24 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Ping timeout: 255 seconds] 06:36 -!- jtimon [~quassel@117.29.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 07:19 < kanzure> https://www.tillett.info/2016/08/03/carnot-efficient-dyson-spheres-are-undetectable-by-infrared-surveys/ 07:19 < kanzure> https://news.ycombinator.com/item?id=14526933 07:20 -!- jaboja [~jaboja@jaboja.pl] has quit [Quit: Leaving] 07:31 -!- NikopolSohru [~NSohru@185.145.66.252] has joined ##hplusroadmap 07:50 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 07:54 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Ping timeout: 240 seconds] 08:05 -!- sbodin [~sbodin@91.226.141.253] has quit [Ping timeout: 255 seconds] 08:14 -!- preview [~preview@2407:7000:842d:4078:ab39:1b65:59a7:cd65] has quit [Remote host closed the connection] 08:15 -!- preview [~preview@2407:7000:842d:4078:ab39:1b65:59a7:cd65] has joined ##hplusroadmap 08:31 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 08:32 -!- preview [~preview@2407:7000:842d:4078:ab39:1b65:59a7:cd65] has quit [Ping timeout: 240 seconds] 08:43 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 258 seconds] 08:59 < kanzure> .title https://www.youtube.com/watch?v=89iKgdQSbEE 08:59 < yoleaux> Liz Parrish (BioViva CEO) interviewed by Sarah Westall (09/06/2017) - YouTube 09:02 < kanzure> .title https://vimeo.com/219562593 09:02 < yoleaux> Humanist Community Forum (2017-04-30): Cryonics - Preserving Ourselves for the Future (Dr. Ralph Merkle) on Vimeo 09:19 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 09:20 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 09:25 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Ping timeout: 240 seconds] 09:35 -!- JenElizabeth [~Jen3@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 240 seconds] 09:36 < JayDugger> Huh. Thanks for the link to the Merkle talk. 09:43 -!- Guest32508 is now known as abetusk 09:47 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 10:24 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 10:35 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 10:39 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 10:46 -!- jenelizabeth_ [~jenelizab@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 11:22 -!- Jen [~Jen3@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 11:26 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Remote host closed the connection] 11:31 -!- sbodin [~sbodin@91.226.141.253] has joined ##hplusroadmap 11:31 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 11:59 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit 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14:47 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 14:48 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 14:49 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 15:10 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 15:12 -!- emeraldgreen [~user@188.227.115.178] has joined ##hplusroadmap 15:34 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 15:38 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has quit [Ping timeout: 246 seconds] 15:41 -!- emeraldgreen [~user@188.227.115.178] has quit [Ping timeout: 260 seconds] 15:54 -!- emeraldgreen [~user@188.227.115.178] has joined ##hplusroadmap 16:00 -!- preview [~preview@118-92-220-128.dsl.dyn.ihug.co.nz] has joined ##hplusroadmap 16:02 -!- HEx1 [~HEx@hexwab.plus.com] has quit [Remote host closed the connection] 16:06 -!- HEx1 [~HEx@hexwab.plus.com] has joined ##hplusroadmap 16:07 -!- jtimon [~quassel@117.29.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 16:12 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:d9fa:7ec5:183f:f076] has joined ##hplusroadmap 16:35 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds] 16:43 -!- cluckj [~cluckj@pool-108-52-166-30.phlapa.fios.verizon.net] has quit [Ping timeout: 268 seconds] 16:44 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 255 seconds] 16:48 -!- augur [~augur@2601:643:8400:9b9b:90cf:201e:3de7:2570] has joined ##hplusroadmap 17:04 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-seavntqekwixdnjj] has quit [Quit: Connection closed for inactivity] 17:10 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 268 seconds] 17:14 -!- emeraldgreen [~user@188.227.115.178] has quit [Quit: Leaving.] 17:14 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 17:29 -!- emeraldgreen [~user@188.227.115.178] has joined ##hplusroadmap 17:53 -!- emeraldgreen [~user@188.227.115.178] has quit [Quit: Leaving.] 18:01 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 18:01 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 240 seconds] 18:32 < kanzure> "A single-cell anatomical blueprint for intracortical information transfer from primary visual cortex" http://biorxiv.org/content/early/2017/06/09/148031 https://twitter.com/biorxivpreprint/status/873238367357599744 18:34 < kanzure> https://www.statnews.com/2017/06/08/george-church-narcolepsy/ https://twitter.com/wyssinstitute/status/872852768435908611 18:36 < kanzure> https://www.technologyreview.com/s/608073/gene-editing-companies-hit-back-at-paper-that-criticized-crispr/ https://twitter.com/techreview/status/873250739677736960 18:41 < kanzure> "The promise of organ and tissue preservation to transform medicine" http://www.nature.com/nbt/journal/v35/n6/full/nbt.3889.html https://twitter.com/NatureBiotech/status/872633971833790464 18:42 < kanzure> "Chimeric CRISPR guides enhance Cas9 target specificity" http://biorxiv.org/content/early/2017/06/08/147686 https://twitter.com/biorxivpreprint/status/872936300420235265 18:43 < kanzure> "Rich cell-type-specific network topology in neocortical microcircuitry" https://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.4576.html 18:43 < kanzure> from https://twitter.com/wake_sleep/status/872081556587859969 18:44 < kanzure> "Here we map the projection patterns of axonal arbors from 595 individual neurons in mouse primary visual cortex (V1) using two complementary methods: whole-brain fluorescence-based axonal tracing and high-throughput DNA sequencing of genetically barcoded neurons (MAPseq). Although our results confirm the existence of dedicated projections to certain cortical areas, we find these are the excep... 18:44 < kanzure> ...tion, and that the majority of V1 neurons broadcast information to multiple cortical targets. Furthermore, broadcasting cells do not project to all targets randomly, but rather comprise subpopulations that either avoid or preferentially innervate specific subsets of cortical areas. Our data argue against a model of dedicated lines of inter-areal information transfer via "one neuron -- one ta... 18:44 < kanzure> ...rget area" mapping. Instead, long-range communication between a sensory cortical area and its targets is based on a principle whereby individual neurons copy information to, and potentially coordinate activity across, specific subsets of cortical areas." 18:56 < kanzure> "whole-brain fluorescence-based axonal tracing" 18:57 < kanzure> "Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers" https://www.nature.com/articles/nmicrobiol2016162 19:36 < kanzure> .wik larotrectinib 19:36 < yoleaux> "Larotrectinib (LOXO-101, ARRY-470) is an experimental drug for the treatment of cancer. It is an inhibitor of tropomyosin kinase receptors TrkA, TrkB, and TrkC. It was discovered by Array BioPharma and licensed to Loxo Oncology in 2013." -- https://en.wikipedia.org/wiki/Larotrectinib 19:37 < kanzure> https://www.loxooncology.com/docs/presentations/Hyman_Larotrectinib_ASCO_2017_FINAL.PDF 20:36 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 255 seconds] 22:07 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 240 seconds] 22:17 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 22:18 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 22:30 -!- jtimon [~quassel@117.29.134.37.dynamic.jazztel.es] has quit [Ping timeout: 246 seconds] 22:51 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap 23:05 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:d9fa:7ec5:183f:f076] has quit [Quit: Leaving] 23:37 -!- sbodin [~sbodin@91.226.141.253] has quit [Ping timeout: 260 seconds] --- Log closed Sun Jun 11 00:00:19 2017