--- Log opened Sun Oct 08 00:00:40 2017 00:11 -!- zephyr1 [~zephyr1@77.247.178.186] has quit [Quit: My MacBook has gone to sleep. 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(@finchtalk) 07:38 < kanzure> .tw https://twitter.com/MoleculeWorld/status/915647104596316160 07:38 < yoleaux> George Church: We can engineer MHC class I proteins to make tissues compatible for transplantation. #SBBSF17 https://pbs.twimg.com/media/DLUILu6UQAA9axz.jpg (@MoleculeWorld) 07:38 < kanzure> .tw https://twitter.com/GeneMods/status/915620389195255808 07:38 < yoleaux> Wow. $35 billion in new lab equipment purchased every year. Wonder what the avg/median cost/instrument is, and price ∆ over time. #sbbsf17 (@GeneMods) 07:38 < kanzure> .tw https://twitter.com/TwistBioscience/status/915609456997797888 07:38 < yoleaux> Pushing #synbio to a new level—Our historic deal w @Ginkgoo for a 1B genes to power their new foundry: https://buff.ly/2g5NVrV #DNA (@TwistBioscience) 07:39 < kanzure> .tw https://twitter.com/GeneMods/status/915212838607650817 07:39 < yoleaux> We interviewed @DrewEndy about the 10k free genes project and the creation of a biotechnology commons! #synbio https://soundcloud.com/user-632262556-831246168/5-genemods-extra-the-10k-genes-project-w-professor-drew-endy (@GeneMods) 07:40 < kanzure> https://soundcloud.com/user-632262556-831246168/5-genemods-extra-the-10k-genes-project-w-professor-drew-endy 07:45 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 08:02 -!- rpifan [~rpifan@73.106.73.1] has joined ##hplusroadmap 08:06 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 258 seconds] 08:14 -!- rpifan_ [~rpifan@73.106.72.161] has joined ##hplusroadmap 08:17 -!- rpifan [~rpifan@73.106.73.1] has quit [Ping timeout: 248 seconds] 08:18 -!- rpifan_ [~rpifan@73.106.72.161] has quit [Client Quit] 08:19 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 08:22 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 08:32 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 255 seconds] 08:58 -!- mf1008 [~mf1008@unaffiliated/mf1008] has quit [Quit: Cave quid dicis, quando, et cui] 08:59 -!- mf1008 [~mf1008@unaffiliated/mf1008] has joined ##hplusroadmap 09:10 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 09:12 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 09:14 -!- emeraldgreen [~user@188.227.115.178] has quit [Ping timeout: 264 seconds] 09:15 -!- emeraldgreen [~user@70.ip-145-239-90.eu] has joined ##hplusroadmap 09:19 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 09:20 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 09:45 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 264 seconds] 09:59 -!- emeraldgreen [~user@70.ip-145-239-90.eu] has quit [Quit: Leaving.] 10:03 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 10:27 < kanzure> .title https://www.youtube.com/watch?v=rrZk9sSgRyQ 10:27 < yoleaux> BLADE RUNNER 2049 - "Black Out 2022" Anime Short - YouTube 10:52 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 11:02 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 11:02 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Client Quit] 11:02 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 11:03 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 240 seconds] 11:19 -!- Coming [~Coming@55.92-220-69.customer.lyse.net] has joined ##hplusroadmap 11:36 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 11:56 -!- augur [~augur@2600:380:4551:9f42:406f:45f6:b41f:6516] has joined ##hplusroadmap 11:58 -!- mindsForge [~nak@75-172-169-191.phnx.qwest.net] has quit [Quit: Leaving.] 11:58 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 248 seconds] 11:59 -!- mindsForge [~nak@75-172-169-191.phnx.qwest.net] has joined ##hplusroadmap 12:15 -!- zephyr1 [~zephyr1@172.58.139.40] has joined ##hplusroadmap 12:16 -!- augur [~augur@2600:380:4551:9f42:406f:45f6:b41f:6516] has quit [Remote host closed the connection] 12:18 -!- augur [~augur@2600:380:4551:9f42:c03c:167:59f9:db1c] has joined ##hplusroadmap 12:20 -!- augur [~augur@2600:380:4551:9f42:c03c:167:59f9:db1c] has quit [Remote host closed the connection] 12:27 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 248 seconds] 12:47 -!- augur [~augur@2600:380:4551:9f42:ac88:5b85:2a1:a931] has joined ##hplusroadmap 12:50 -!- augur [~augur@2600:380:4551:9f42:ac88:5b85:2a1:a931] has quit [Remote host closed the connection] 12:52 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 12:59 -!- zephyr1 [~zephyr1@172.58.139.40] has quit [Ping timeout: 255 seconds] 13:05 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 13:16 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 240 seconds] 13:19 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 13:19 -!- mindsForge [~nak@75-172-169-191.phnx.qwest.net] has quit [Remote host closed the connection] 13:20 -!- mindsForge [~nak@75-172-169-191.phnx.qwest.net] has joined ##hplusroadmap 13:21 < heath> i've been keeping up with holochain. the people behind it have been thinking about alt currencies before bitcoin. they are the metacurency folk, and they aren't trying to "cash in." they are just approaching the problem of wealth distribution differently 13:21 < heath> that should somehow be sent to eudoxia 13:22 < heath> i've a few more thoughts that are more concrete, but i'd rather just have a conversation with eudoxia 13:31 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 13:42 < heath> nmz787: mind linking to "paper describing a high-volume manufacture technique for making a nice 3-electrode sandwich through the nanopore"? 13:42 < heath> oh, i just needed to keep reading, ignore :) 13:52 < heath> https://cloud.google.com/storage/archival/ 13:53 < heath> didn't realize google had a public facing service for cold storage 13:56 < heath> and it's cheaper than glacier at 0.007/gb 13:59 < heath> http://www.quickbase.com/customers/google-manages-sox-compliance-efforts-with-intuit-quickbase 14:02 < heath> https://www.syscloud.com/blog/sox-compliance-through-google-apps/ 14:05 < heath> biz idea: store data in your dna archival solution and offer integrations with slack, google apps, and quick base for sox compliance 14:14 -!- strages [uid11297@gateway/web/irccloud.com/x-dlsaobqnuxifevui] has joined ##hplusroadmap 14:17 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 14:22 < streety> heath: not difficult to find cheaper services than amazon glacier 14:22 < streety> https://wasabi.com/pricing/ 0.0039/GB/month 14:23 < streety> https://www.backblaze.com/b2/cloud-storage-pricing.html 0.005/GB/month 14:24 < streety> those both offer install access at sub-glacier pricing 14:24 < streety> *instant 14:26 < heath> oh wait, glacier is 0.004/gb. not sure what was going on in my brain 14:28 < streety> glacier is difficult to price, the access fees can be complex and get high quickly. google seemed less likely to surprise 14:41 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Ping timeout: 260 seconds] 14:51 -!- Coming [~Coming@55.92-220-69.customer.lyse.net] has quit [Ping timeout: 255 seconds] 14:55 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 14:57 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 14:58 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Client Quit] 14:58 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 260 seconds] 14:58 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 15:05 -!- aeiousomething [~aeiousome@223.237.58.220] has joined ##hplusroadmap 15:05 -!- aeiousomething [~aeiousome@223.237.58.220] has quit [Client Quit] 15:06 -!- aeiousomething [~aeiousome@223.237.58.220] has joined ##hplusroadmap 15:08 -!- aeiousomething [~aeiousome@223.237.58.220] has quit [Read error: Connection reset by peer] 15:11 -!- aeiousomething [~aeiousome@223.237.58.220] has joined ##hplusroadmap 15:15 -!- Proteus [~Proteus@unaffiliated/proteus] has joined ##hplusroadmap 15:40 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 15:42 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 240 seconds] 15:48 < kanzure> heath: tell me about "open currency" things from 2008 16:09 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 16:15 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 16:15 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 16:27 -!- aeiousomething [~aeiousome@223.237.58.220] has quit [Ping timeout: 258 seconds] 16:37 < heath> in short... ernie yacub headed the open money project which aimed to allow communities to create thier own variants of https://en.wikipedia.org/wiki/Local_exchange_trading_system 16:37 < heath> arthur brock and eric harris braun are the metacurrency project. they essentially think there are various forms of wealth and they are still trying to create an open platform for managing and exchanging this wealth. 16:37 < heath> http://metacurrency.org/wp-content/uploads/2016/05/Levels-of-Wealth_Water.png 16:41 < heath> here is the latest effort: http://ceptr.org i'd like to see more effort around maintaining local sources of truth / independence from a central source of truth 16:42 < heath> iirc, the kerberos folk at mit hosted a meeting with them awhile back 16:49 < kanzure> why was there there was lots of "open money" stuff flying around in 2008? 16:49 < heath> not sure 16:49 < heath> 10.1038/319618a0 "The RNA world" 16:51 < heath> oh, right. there was a financial crisis around that time 16:51 < heath> ^ re: why "open money" around 2008 16:52 < kanzure> ah i see. 16:52 < kanzure> heath: but why did satoshi go to p2pfoundation of all places? 16:52 < kanzure> (i know one possible reason but it's a little weird.) 16:58 < heath> because it was a way for him to find others who might be interested in the idea? 16:59 < kanzure> ah but there were many places. 16:59 < kanzure> except this place was special for a certain reason 16:59 < heath> her/him/it 16:59 < heath> her/him/they rather 16:59 < kanzure> the p2pfoundation mailing list subscriber list was actually the same as some prior p2p hacker mailing lists (i think possibly started by bram cohen and/or others) 17:00 < kanzure> the mailing lists had been morphed and copied multiple times into different fungus/spore child mailing lists 17:00 < kanzure> so it is conceivable that it was someone who was an original subscriber 17:00 < kanzure> http://diyhpl.us/~bryan/irc/bitcoin-satoshi/mailing-lists.txt 17:00 < heath> makes sense 17:00 < kanzure> http://diyhpl.us/~bryan/irc/bitcoin-satoshi/p2p-research-members.txt.tar 17:00 < kanzure> http://diyhpl.us/~bryan/irc/bitcoin-satoshi/ning-users-p2pfoundation-2013-05-19.pdf 17:01 < kanzure> 208 and 273.. heh. 17:05 < heath> yeah, i just had a laugh. i wish i were that person right about now given my terrible financial choice quiting and then looking for new work 17:05 < heath> +of 17:06 < kanzure> have some music https://www.youtube.com/watch?v=p2rIOTby0gk&t=22m3s 17:06 < kanzure> .title 17:06 < yoleaux> Carbon Based Lifeforms "Derelicts" [Full Album - 2017] - YouTube 17:09 < heath> #entertainment tv: the orville (sci-fi star trek parody tv show). short films: HENRi - https://vimeo.com/61686359 C - https://vimeo.com/58429056 17:13 < superkuh> It isn't a star trek parody. 17:13 -!- zephyr1 [~zephyr1@172.58.139.82] has joined ##hplusroadmap 17:13 < superkuh> It may be marketed that way to avoid litigation. But it's more Trek than Discovery is. 17:14 < heath> star trek like parody* 17:14 < kanzure> zephyr1: hi. 17:14 < superkuh> It's not parody though. 17:15 < superkuh> It has comedy, but it's not a parody of anything. 17:16 < heath> ok :) i guess that's a useful clarification 17:17 -!- zephyr1 [~zephyr1@172.58.139.82] has quit [Client Quit] 17:23 -!- mindsForge [~nak@75-172-169-191.phnx.qwest.net] has quit [Remote host closed the connection] 17:30 < heath> https://www.autm.net/resources-surveys/material-transfer-agreements/uniform-biological-material-transfer-agreement/ 17:31 < heath> "addgene defaults right now to the UBMTA, which disallows redistribution of the material, so if you get a plasmid from them, which is great and way better than what's happened before, you can't redistribute that to somebody else, like a lab in your building." 17:33 < heath> "similarly, if you're a startup company,..., although addgene might wish to provision you stuff to get started, they actually can't because the UBMTA disallows commercial use." 17:33 < heath> https://www.openplant.org/openmta/ 17:35 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 260 seconds] 17:35 < heath> "the major difference between the openmta and the UBMTA is the openmta purposefully allows for redistribution and purposefully allows for commercial use" 17:36 < kanzure> is this because universities require material transfer agreements, and you have to write something down? why not just give it to them anyway without an agreement? 17:37 < heath> if you don't specify one, e.g., stanford will default to UBMTA 17:39 < heath> this is coming directly from https://soundcloud.com/user-632262556-831246168/5-genemods-extra-the-10k-genes-project-w-professor-drew-endy 17:53 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 17:56 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 17:59 < heath> /win 11 18:14 < kanzure> "Large-scale screening of rare genetic variants in humans reveals frequent splicing disruptions" https://www.biorxiv.org/content/early/2017/10/08/199927 https://twitter.com/biorxivpreprint/status/917132595493855232 18:15 < kanzure> "Reconstruction of developmental landscapes by optimal-transport analysis of single-cell gene expression sheds light on cellular reprogramming" https://www.biorxiv.org/content/early/2017/09/27/191056 https://twitter.com/dgmacarthur/status/913375312771207168 18:15 < kanzure> .tw https://twitter.com/brainmaps/status/909038695663259648 18:15 < yoleaux> a now for a little humor! thanks to Tony Zador @TonyZador for directing my attention to this one https://bsdneuro.wordpress.com/ (@brainmaps) 18:16 < kanzure> "Elife – This improbably named blog is not a dating service as I once learned in a most embarrassing mixup that resulted in the formation of several investigatory committees at my university and my participation in an excruciating 15-minute online sensitivity training module. No, the truth is even sillier. The crackpots running this enterprise have the sad and naïve goal of forcing ... 18:16 < kanzure> ...everyone who reviews for them to reveal their identity. I have steadfastly avoided publishing there, yet enduring an occasional round of the review process is a very convenient way to shore up your enemies list." 18:16 < kanzure> "Journal of Neurophysiology – Who are you, Charles Sherrington? Welcome to the 21st century! Studies published here seem to be best described as hybrid undergraduate lab exercises/steampunk cosplays. If I see your paper here, I immediately know three things about you: 1) You’ve got the cleanest recordings around, 2) You’ve never been invited to speak at a Gordon Conference, 3) Your lab ... 18:16 < kanzure> ...looks like a RadioShack in 1980." 18:16 < kanzure> "Nature Protocols – Look, I’m all in favor of methods development, but seriously, why don’t you just title your paper “Here are all my secrets. Please scoop me.” This is a useful receptacle for when you’ve made the classic mistake of hiring a physicist postdoc who has spent the last 7 years building a custom microscope or an immersive VR environment for mouse pups but can’t do ... 18:16 < kanzure> ...an experiment to save their life. Come up with an acronym, dump it here, and move on." 18:19 < kanzure> wat "1. Some methods don’t scale. You might say, “Seems like Markram is running the Human Brain Project like you run your lab, Bob.” True…and a huge mistake. Remember the stick and the carrot? This only works when you put people through repeated cycles of highly personalized and thorough emotional abuse and humiliation followed by kudos and ego stroking. After 6 months of this, a ... 18:19 < kanzure> ...postdoc won’t know if they’re Paul or Ringo, and they will be putty in your hands. What Hank failed to understand is that the BGB style doesn’t work for large, scattered groups: If the betas don’t constantly smell an alpha around, they start to get uppity." 18:19 < kanzure> "The Graybeard Strategic Command Center for Decoding the Brain" 18:21 < kanzure> "Postdocalypse – This refers to the crisis caused by a shocking vacuum of talent and commitment among young scientists. If I’m having trouble finding worthy talent (me!), imagine how hard it must be for the regular working Joe at say Princeton." 18:21 < kanzure> https://twitter.com/BSDneuro 18:22 < kanzure> .tw https://twitter.com/BSDneuro/status/909815857802629122 18:22 < yoleaux> Happy postdoc appreciation day to those of you whose progress is adequate. There are potato chips in the break room. https://twitter.com/BSDneuro/status/451392704858304513 (@BSDneuro) 18:29 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap 18:29 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 18:30 < heath> didn't realize walmart has its own data center. kind of makes sense 18:30 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 18:32 < heath> their customer transaction data is generating ≈2.5PB/hr 18:37 < heath> s/generating// 18:39 < nmz787> sup 18:44 < heath> "Currently Walmart processes over 40 Petabytes of data, per day." 18:45 < heath> https://en.wikipedia.org/wiki/Area_71 18:46 < nmz787> huh 18:46 < jrayhawk> haha that wikipedia article must be ancient 18:47 < nmz787> the ref is from 2013 18:47 < jrayhawk> 480 terabytes is a single 4u backblaze storage pod chassis 18:49 < heath> i think the exact numbers are kept secret. harvard biz review was saying 2.5PB/hr in 2012 and a forbes article from jan of this year says is where the 40PB/day quote came from 18:49 < heath> s/says// 18:50 < kanzure> http://diyhpl.us/~nmz787/pdf/Sequence_control_in_polymer_synthesis.pdf 18:50 < heath> guess that sounds like a conspiracy theory, so feel free to ignore 18:57 < nmz787> https://snf.stanford.edu/SNF/processes/ee412/fall-11/EE412%20Final%20Report-ALD%20Conformality_final.pdf 18:57 < nmz787> Characterization of Fiji ALD Film Quality and Conformality in High Aspect Ratio/Deep Etched Structures 18:57 < nmz787> stanford's research lab has one https://snf.stanford.edu/SNF/equipment/chemical-vapor-deposition/ald/fiji-r 18:57 < nmz787> idk if it is available for hire 18:58 < nmz787> Film: Plasma Pt; Deposition rate (A/cycle) @ temp): 0.5 18:58 < nmz787> (that's Angstroms) 18:59 < kanzure> film is still higher performance than other stuff? 18:59 < nmz787> this is just what they call nanofab 18:59 < nmz787> thin films 18:59 < nmz787> and atomic monolayers are the thinnest, I guess 18:59 < nmz787> unless we can someday do some weird sub-atomic deposition 18:59 < nmz787> neutrons? 19:00 < nmz787> basically it's a way of saying we can get half-nanometer wide Platinum electrode with that machine 19:02 < kanzure> i haven't looked at the actual max write density for thin film stuff... silver halide crystal matrices or otherwise. 19:02 < nmz787> apparently the wiki for platinum says the atomic radius is 1.39 angstroms 19:02 < nmz787> this is how they make any mems stuff in high volumes 19:03 < nmz787> https://microlab.berkeley.edu/text/seminars/slides/VTT_ALD.pdf 19:03 < nmz787> Brief Overview of Microsystems and Nanoelectronics 19:05 < heath> i keep in contact with this guy if his experience is useful https://scholar.google.com/citations?user=uxJk2bQAAAAJ&hl=en&oi=sra 19:05 < nmz787> kanzure: the time for ALD (atomic layer deposition) is typically around 50nm per hour 19:06 < nmz787> heath: yeah I guess ask if he knows about atomic-layer deposition of metals... specifically non-reactive ones 19:07 < kanzure> music https://www.youtube.com/watch?v=p2rIOTby0gk&t=28m30s 19:07 < heath> nmz787: what exactly do you want to know about this? 19:07 < heath> still figuring it out? 19:08 -!- fleshtheworld [~fleshthew@c-66-41-209-167.hsd1.mn.comcast.net] has joined ##hplusroadmap 19:08 < nmz787> heath: yeah, i'd just be interested in the first response to that question really. 19:10 < nmz787> heath: specifically, non-reactive in electrochemistry at say sub-100 Volts, or maybe less than 20 Volts 19:10 < nmz787> i.e. electrophoresis voltages at nanofluidic scale 19:20 < kanzure> more musics https://www.youtube.com/watch?v=p2rIOTby0gk&t=40m40s 19:23 -!- mindsForge [~nak@75-172-169-191.phnx.qwest.net] has joined ##hplusroadmap 19:24 < kanzure> https://www.youtube.com/results?search_query=MEMS2013 19:25 < kanzure> .title https://www.youtube.com/playlist?list=PLgO7JBj821uFpjgJdPgtLx6bprye9XvIs 19:25 < yoleaux> mems - YouTube 19:40 < nmz787> I couldn't really find anyone offering contract fab services for MEMS 19:41 < nmz787> where we could i.e. get RIE and ALD done to make some nanopores 19:48 < nmz787> NIR interferometer (found via that VTT link above) https://store.vaisala.com/us/products/product/GMP25210A0A0N1/gmp252-carbon-dioxide-probe-for-ppm-level-measurements?_ga=2.124131978.1432688761.1507420409-2076295685.1507420409 19:48 < nmz787> $650 20:36 -!- Gurkenglas [~Gurkengla@dslb-094-223-135-191.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 255 seconds] 20:42 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Quit: Leaving...] 21:14 -!- jtimon [~quassel@199.31.134.37.dynamic.jazztel.es] has quit [Ping timeout: 248 seconds] 22:10 < heath> http://www.ebay.com/itm/QIClick-Color-QImaging-camera-12-Bit-High-Tech-Lab-Photomicrography-/222660319895?hash=item33d796da97:g:OKsAAOSwBdhZzwsZ 22:10 < heath> also $650 22:11 < heath> was looking for https://www.qimaging.com/products/cameras/scientific/exi_aqua.php on ebay to get a price estimate 22:12 < heath> related: https://www.elphel.com/wiki/Sensors_table 22:33 < heath> .title https://www.nytimes.com/interactive/2017/08/04/science/crispr-gene-editing.html 22:33 < yoleaux> Can Gene Editing Actually Do That? - The New York Times 22:33 < heath> "...even if the United States decides that only certain types of modifications are legal, other countries can opt to approach the matter entirely differently. And so yes, one day a small, unexpected town somewhere may become the Amsterdam of gene editing; a place where so long as you have money, any snip goes." 22:44 < nmz787> ;) 22:57 -!- fleshtheworld [~fleshthew@c-66-41-209-167.hsd1.mn.comcast.net] has quit [Quit: Leaving] 23:22 < nmz787> https://lirias.kuleuven.be/bitstream/123456789/496274/1/thesis.pdf 23:22 < nmz787> metallic nanopores for single-molecule DNA sensing 23:22 < nmz787> The term “Plasmon” is used to describe the collective oscillations of the free electron gas density – a type of electro-magnetic properties of metals. The rapid oscillations of the electron density in the body of conducting media are bulk plasmons, while surface plasmons are the electro-magnetic excitations between a metal and a dielectric interface. Figure 1.12 show two types of surface 23:22 < nmz787> plasmons. To understand the “Plasmon”, we need to characterize the oscillation of free electrons. For bulk plasmon, it can be described by its dispersion relation, which can be derived from classical Maxwell equations as following 23:24 < nmz787> kbulk = ω/c(√ εm) = ω/c(√(1 − ωp^2/ω2)) 23:24 < nmz787> where kbulk is the wave vector of the bulk plasmon, ω is the angular frequency, c is the speed of light in the vacuum, εm is the dielectric constant of the metal. The dielectric constant of the metal can be expressed with the plasmon frequency ωp which is an intrinsic property of a given metal. 23:25 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 23:27 < nmz787> Below the plasmon frequency ω < ωp, we cannot obtain a real wave vector. Therefore, there is no propagation of electro-magnetic waves in this region. In most metals, the plasma frequency is in the ultra-violet regime. For surface plasmons, we can obtain the wave vector at the the metal and the dielectric interface as ksp = ω/c(√((εm * εd)/(εm + εd)) where ω is the angular frequency, c is 23:27 < nmz787> the speed of light in the vacuum, εm is the dielectric constant of the metal and εd is the dielectric constant of the dielectric medium. Surface plasmons can thus exist only when a metal εm<0 and a dielectric medium εd>0 and fulfill εm=-εd. The dispersion relationship for surface plasmons is shown as the red curve in Figure 1.12a. Resonant surface plasmons (or more exactly surface plasmon 23:27 < nmz787> polaritons, SPPs) can propagate along the interface between a metal and a dielectric medium. 23:28 < nmz787> from the section "METALLIC NANOPORES WITH SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS)" 23:47 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-hcvpfturammsypgm] has quit [Quit: Connection closed for inactivity] 23:51 < nmz787> Figure 1.15 shows our strategy for nanopore fluidics SERS and the electro-magnetic field enhancement inside the nanopore. Compared to the conventional nanopore sequencing method based on ionic current nanofluidics, we are combining surface enhanced Raman spectroscopy (SERS) with solid-state nanopores for real-time DNA detection or even sequencing (as a long-term goal). 23:51 < nmz787> then they go and mention that the same optics you're using to sense this, can be illuminated on the nanopore, and act as optical tweezers 23:52 < nmz787> hmm, I wonder if you can use ALD to deposit optically-clear films --- Log closed Mon Oct 09 00:00:41 2017