--- Log opened Tue Nov 28 00:00:28 2017 00:11 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap 00:13 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 258 seconds] 01:16 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 01:43 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 276 seconds] 01:52 -!- rpifan [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has quit [Quit: Leaving] 01:53 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 01:53 -!- rpifan [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has joined ##hplusroadmap 02:09 -!- rpifan_ [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has joined ##hplusroadmap 02:09 -!- rpifan [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has quit [Read error: Connection reset by peer] 02:14 -!- rpifan_ [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has quit [Ping timeout: 248 seconds] 02:48 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection] 02:56 -!- DataPacRat [~dan@adsl-107.itcanada.com] has joined ##hplusroadmap 02:58 -!- bluebear_ [~dluhos@80.95.97.194] has joined ##hplusroadmap 03:46 -!- jtimon [~quassel@164.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 03:48 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 260 seconds] 04:10 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 04:38 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 05:45 -!- DataPacRat [~dan@adsl-107.itcanada.com] has quit [Ping timeout: 240 seconds] 06:02 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 255 seconds] 06:10 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 06:13 < kanzure> justanotheruser: okay, i have sent an email to freitas asking about that book. 06:13 < kanzure> "Bacterial glycosidases for the production of universal red blood cells" https://www.nature.com/articles/nbt1298 06:14 < kanzure> "Reconstitution in vitro of the entire cycle of the mouse female germ line" https://www.nature.com/articles/nature20104 06:17 < justanotheruser> thanks! 06:58 -!- DataPacRat [~dan@adsl-107.itcanada.com] has joined ##hplusroadmap 07:03 -!- augur [~augur@2600:380:477f:5788:dd5a:80bd:7714:7d36] has joined ##hplusroadmap 07:05 -!- NikopolSohru [~NSohru@185.212.171.77] has joined ##hplusroadmap 07:11 < JayDugger> Yes, thank you for doing that, kanzure. 07:14 -!- mindsForge [~nak@75-171-23-2.phnx.qwest.net] has joined ##hplusroadmap 07:50 -!- augur [~augur@2600:380:477f:5788:dd5a:80bd:7714:7d36] has quit [Ping timeout: 255 seconds] 07:51 -!- augur [~augur@2600:380:454d:5b73:5169:35c9:5038:cb8] has joined ##hplusroadmap 08:54 -!- augur_ [~augur@2600:380:4575:2ebd:e993:6938:c7:bfd1] has joined ##hplusroadmap 08:58 -!- augur [~augur@2600:380:454d:5b73:5169:35c9:5038:cb8] has quit [Ping timeout: 276 seconds] 09:05 -!- augur_ [~augur@2600:380:4575:2ebd:e993:6938:c7:bfd1] has quit [Remote host closed the connection] 09:09 -!- DataPacRat [~dan@adsl-107.itcanada.com] has quit [Ping timeout: 260 seconds] 09:38 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection] 09:40 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 09:46 -!- jtimon [~quassel@164.31.134.37.dynamic.jazztel.es] has quit [Remote host closed the connection] 10:06 < kanzure> .title https://www.youtube.com/watch?v=MiDKOkdbAEg 10:06 < yoleaux> World's smallest tape recorder is built from microbes - YouTube 10:06 < kanzure> "Multiplex recording of cellular events over time on CRISPR biological tape" http://science.sciencemag.org/content/early/2017/11/20/science.aao0958 10:06 < kanzure> oh same one. 10:07 < gradstudentbot> Should this be on ice? 10:07 < kanzure> "CRISPR/Cas9-mediated targeted chromosome elimination" https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1354-4 10:08 < kanzure> https://www.genomeweb.com/gene-silencinggene-editing/crispr-used-eliminate-targeted-chromosomes-new-study 10:08 < kanzure> "Parents may one day be morally obligated to edit their baby’s genes" https://www.sciencenews.org/blog/science-public/ethics-gene-editing-babies-crispr 10:26 < kanzure> .title http://www.cnn.com/2017/09/21/health/uk-human-embryos-crispr-fertility-study/index.html 10:26 < yoleaux> Gene editing of human embryos in UK reveals new fertility clue - CNN 10:28 < gradstudentbot> I am busy researching. 10:31 < bluebear_> kanzure: I believe they are talking about +100 years, at least :-) 10:32 < bluebear_> (regarding the moral obligation to edit baby genes) 10:35 < kanzure> are those internet years or non-internet years? 10:36 < gradstudentbot> The real reason I wanted to join this lab was because I love to clean glassware. 10:37 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 10:43 < spurserh> @gradstudentbot I love to clean glassware, too. we should hang out some time 10:43 < gradstudentbot> Oh, that's problematic. 10:43 < spurserh> haha 10:45 < kanzure> spurserh: he's based on this video https://www.youtube.com/watch?v=ovEghdXC4tE 10:48 < bluebear_> kanzure: I meant 100 normal years (orbits of Earth around the sun); the way from lab to clinic is usually much, much slower than one would guess 10:48 < spurserh> "Gaahd why won't they just kick me out" 11:13 -!- bluebear_ [~dluhos@80.95.97.194] has quit [Quit: Leaving.] 11:33 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has joined ##hplusroadmap 11:35 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection] 11:36 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 11:41 -!- juri_ [~juri@205.166.94.162] has joined ##hplusroadmap 11:56 -!- mindsForge [~nak@75-171-23-2.phnx.qwest.net] has quit [Remote host closed the connection] 11:59 -!- jtimon [~quassel@164.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 12:07 -!- eudoxia [~eudoxia@190.99.101.24] has joined ##hplusroadmap 12:23 < kanzure> something is coming online for neuronal branching/targeting in monkeys soon. 12:25 < kanzure> so if you have specific neuroanatomical changes you want.. start writing it down. 12:25 < spurserh> something coming online? you mean a process becoming commercially available? 12:28 < kanzure> zymergen has been doing directed evolution with their $100M 12:28 < kanzure> (just some notes on a phone call i'm having) 12:40 < kanzure> church had a stealth ecoli for transfection into humans 12:40 < kanzure> for gene therapy 12:40 < kanzure> we should go fund some european toxoplasma people to do crispr things 12:42 < kanzure> spurserh: you should pick out some ultrasound contrast agents that you like. 12:42 < kanzure> there are some that disrupt BBB 12:43 < kanzure> IVF for designer pets is probably good entry point. 12:46 < kanzure> https://www.asianscientist.com/2017/11/features/asias-rising-scientists-matthew-chang/ 12:57 -!- augur [~augur@192.195.83.130] has joined ##hplusroadmap 12:59 < kanzure> https://techcrunch.com/2016/10/20/bryan-johnson-invests-100-million-in-kernel-to-unlock-the-power-of-the-human-brain/ 12:59 < JayDugger> Still phone notes? 12:59 < kanzure> no 13:04 -!- eudoxia [~eudoxia@190.99.101.24] has quit [Quit: Leaving] 13:28 < kanzure> https://architecht.io/the-immense-promise-and-practical-limitations-of-machine-learning-in-biochemistry-f37f0c927827 13:29 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 13:32 -!- Guest32445 [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 13:42 -!- JayDugger [~jwdugger@47.185.237.246] has quit [Ping timeout: 268 seconds] 15:45 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 240 seconds] 15:46 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 15:52 < kanzure> https://capability.party/memes/2017/09/11/constant-flawless-vigilance.html 16:01 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 276 seconds] 16:17 < juri_> wanted: a cambridge stereoscan 200 scanning electron microscope. for hacking. 16:19 < juri_> I have one, and want a second for parts. 16:23 < kanzure> how much? 16:24 < juri_> I can scrounge together a few K, and transport from most places on the east coast. 16:24 < juri_> possibly more, depending on condition. i'm refurbing the one i have, and it is a slow process. 16:24 < juri_> (down to .34 torr! find those leaks!) 16:37 -!- rpifan [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has joined ##hplusroadmap 16:38 < justanotheruser> freitas say anything? 16:42 < kanzure> no reply 16:43 -!- mindsForge [~nak@75-171-23-2.phnx.qwest.net] has joined ##hplusroadmap 16:48 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 16:53 < justanotheruser> ok, thanks anyways 17:19 -!- preview [~quassel@2407:7000:842d:4000::2] has quit [Ping timeout: 276 seconds] 17:24 -!- sivoais [~zaki@unaffiliated/sivoais] has quit [Ping timeout: 258 seconds] 17:30 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 18:10 -!- DataPacRat [~dan@adsl-107.itcanada.com] has joined ##hplusroadmap 18:10 < kanzure> .title https://www.youtube.com/watch?v=3b7BE8HRyWw 18:10 < yoleaux> Gada Prize Submission Video for Snappy RepRap - YouTube 18:20 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 276 seconds] 18:20 < kanzure> .title https://www.youtube.com/watch?v=dZT1-EUbJJs 18:20 < yoleaux> Reprap Morgan family working together - YouTube 18:24 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 18:25 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 248 seconds] 18:35 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 19:29 -!- DataPacRat [~dan@adsl-107.itcanada.com] has quit [Ping timeout: 260 seconds] 19:45 -!- DataPacRat [~dan@adsl-12.itcanada.com] has joined ##hplusroadmap 19:45 < kanzure> why are you guys so boring 19:51 < kanzure> .wik infliximab 19:51 < yoleaux> "Infliximab (trade names Remicade among others) is a chimeric monoclonal antibody biologic drug that works against tumor necrosis factor alpha (TNF-α) and is used to treat autoimmune diseases." — https://en.wikipedia.org/wiki/Infliximab 20:01 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 268 seconds] 20:03 -!- mindsForge [~nak@75-171-23-2.phnx.qwest.net] has quit [Quit: Leaving.] 20:06 < kanzure> yashgaroth: also there was that crispr chromosome deletion thing earlier today 20:06 < yashgaroth> but I like my chromosomes 20:07 < kanzure> do you 20:07 < yashgaroth> eh...hit or miss, yea 20:11 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection] 20:29 -!- sivoais [~zaki@unaffiliated/sivoais] has quit [Ping timeout: 240 seconds] 20:30 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 20:30 -!- mindsForge [~nak@75-171-23-2.phnx.qwest.net] has joined ##hplusroadmap 20:39 -!- DataPacRat [~dan@adsl-12.itcanada.com] has quit [Ping timeout: 240 seconds] 20:39 -!- sivoais [~zaki@unaffiliated/sivoais] has quit [Ping timeout: 276 seconds] 20:40 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 20:48 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Remote host closed the connection] 20:51 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 21:30 -!- Jenda_ [~jenda@coralmyn.hrach.eu] has quit [Ping timeout: 240 seconds] 21:32 -!- Jenda [~jenda@coralmyn.hrach.eu] has joined ##hplusroadmap 21:50 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 248 seconds] 21:51 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 21:52 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 22:33 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] 22:35 -!- DataPacRat [~dan@adsl-12.itcanada.com] has joined ##hplusroadmap 22:46 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 268 seconds] 22:49 -!- mindsForge [~nak@75-171-23-2.phnx.qwest.net] has quit [Quit: Leaving.] 22:50 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 22:54 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 22:55 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 23:06 -!- NikopolSohru [~NSohru@185.212.171.77] has quit [Ping timeout: 260 seconds] 23:17 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 23:40 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has joined ##hplusroadmap 23:58 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 250 seconds] --- Log closed Wed Nov 29 00:00:28 2017