--- Log opened Sun Dec 24 00:00:52 2017
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07:31 <@kanzure> ya dont need custom dna for randim tags.... but still need to sequence everything.
07:32 <@kanzure> army of electron microscopes for first version... dna geometty imaging for long-term nondestructive uploading (can redo procedure multiple years later)
07:33 <@kanzure> i think 1e18 base/sec sequencing can be constructed
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12:43 <@kanzure> "one illumina novaseq: 3e12 bases/day. so we just need 33.3 billion Illumina Novaseqs working continuously for one year."
12:45 <@kanzure> also i mentioned to someone else the idea of pre-selling slave uploads/emulations to fund the preservation+uploading costs upfront
12:54 <@kanzure> would be nice to figure out if ion beam milling is really feasible to get all the data out from a 10-30 nm thick slice of brain tissue.  if multi-beam electron microscopy can get all the receptors and other data in this strategy then that's already looking cheaper than sequencing.
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13:04 < jrayhawk> kanzure: is it okay if i compress zc-testnet-public-alpha-proving.key
13:04 < jrayhawk> 2 gigs of plaintext seems a bit ill-advised
13:12 <@kanzure> uhh how about we hash it and check if anyone else on the web has it, then delete it
13:13 < jrayhawk> Yeah, they have it on their s3
13:13 < jrayhawk> https://s3.amazonaws.com/zcashalpha/zc-testnet-public-alpha-proving.key
13:13 <@kanzure> nuke it
13:14 < jrayhawk> Done.
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13:17 <@fenn> i doubt em sources would be valuable commodities anyway. the cost of an em is in running it and training it for the task
13:18 <@fenn> aside from their historical value of course
13:19 <@fenn> also ems are icky. can we please stop talking about it
13:20 <@kanzure> what is ecky about an electron microscope..?
13:20 <@fenn> re: "pre-selling slave uploads/emulations to fund the preservation+uploading costs"
13:21 <@kanzure> icky how?
13:21 <@fenn> the whole person-not-person-sorta-willing-slave thing
13:22 <@fenn> i don't like it
13:22 <@fenn> clear boundaries please
13:22 <@kanzure> you want a rule like "no total enslavement of uploaderkind"?
13:22 <@fenn> yeah that would be great
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13:23 <@fenn> also i have no problem with reverse engineering uploaded connectomes and making neuromorphic AI from that
13:24 <@kanzure> yeah i guess the value of enslavement will be pretty low anyway if market gets flooded
13:25 <@fenn> we still have manual labor, i wonder why
13:25 <@kanzure> because we suck at automation?
13:26 <@fenn> i think because manufacturing is an overly conservative industry
13:26 <@kanzure> where you going to get the money to develop the super manufacturing robots
13:26 <@fenn> normal robots are fine
13:26 <@fenn> but like why are chinese girls putting together consumer electronics
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13:27 <@kanzure> cheaper than robots
13:27 <@fenn> how is that possible
13:27 <@fenn> they could just put together a robot and replace themselves in no time
13:27 <@kanzure> you can find people jut like on the streets
13:27 <@kanzure> *just
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13:43 <@kanzure> i wonder if halcyon's failure tainted the "large number of electron microscopes" plans
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14:34 < nmz787> kanzure: yeah you should be able to shift the FIB beam by 1nm
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14:36 < nmz787> I guess this might need to be done with cryo cooling? otherwise I guess the brain would need fixed somehow, but idk if that is possible (what's faster, whole-brain freezing/vitrfication, or perfusion with fixative?)
14:41 <@kanzure> the brain will be fixed/vitrified with glutaraldehyde
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18:05 <@kanzure> https://www.theguardian.com/science/2017/dec/24/josiah-zayner-diy-gene-editing-therapy-crispr-interview
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23:43 < adlai> .tell CaptHindsight wouldn't it be much easier to employ the spiders GOD gave you rather than try to reverse insect brains?
23:43 < yoleaux> adlai: I'll pass your message to CaptHindsight.
23:43 < adlai> unless you have a god complex, in which case, god right ahead
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--- Log closed Mon Dec 25 00:00:53 2017