--- Log opened Fri Jan 05 00:00:03 2018
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06:21 < kanzure> "Ultrafast near-infrared light-triggered intracellular uncaging to probe cell signalling" https://www.ncbi.nlm.nih.gov/pubmed/29176940
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09:55 < kanzure> .title https://news.ycombinator.com/item?id=16078532
09:55 < yoleaux> Germany vs. Elsevier: universities win temporary free journal access | Hacker News
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15:07 < andytoshi> i'm thinking about buying an amscope b120c-e1 microscope. does anyone have any thoughts about this?
15:13 < MrHindsight> https://www.amazon.com/AmScope-B120C-E1-Siedentopf-Magnification-Illumination/dp/B009VUPIKM
15:14 < MrHindsight> remember to remove the USB cable before viewing with both eyes
15:14 < andytoshi> lol
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15:16 < MrHindsight> andytoshi: check ebay or the auctions for used
15:18 < andytoshi> looks like amazon is cheapest today
15:19 < MrHindsight> only a 1.3MP Camera
15:20 < andytoshi> yeah, it's a crappy camera but it's actually cheaper than the model without a camera because there's a special
15:20 < andytoshi> worst case i throw it away and use my cell cam
15:21 < MrHindsight> you can swap cameras later
15:21 < andytoshi> yeah, that too
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15:29 < kanzure> .wik fluorescence microscope
15:29 < yoleaux> "A fluorescence microscope is an optical microscope that uses fluorescence and phosphorescence instead of, or in addition to, reflection and absorption to study properties of organic or inorganic substances." — https://en.wikipedia.org/wiki/Fluorescence_microscope
15:30 < kanzure> .wik confocal microscopy
15:30 < yoleaux> "Confocal microscopy, most frequently confocal laser scanning microscopy (CLSM), is an optical imaging technique for increasing optical resolution and contrast of a micrograph by means of using a spatial pinhole to block out-of-focus light in image formation." — https://en.wikipedia.org/wiki/Confocal_microscopy
15:31 < andytoshi> i think for now i'll stick with the normal optical one .. this is $200, it looks like fluorescence microscopes are in the $2-10k range
15:31 < andytoshi> so i'd need a pretty good reason :)
15:37 < kanzure> alright
15:37 < nmz787> andytoshi: I got a fluoro scope from a thrift store years ago for <=$50
15:37 < andytoshi> nmz787: oh, cool, i'll keep my eyes open
15:37 < nmz787> yeah that and craigslist can have pretty sporadic-but-awesome deals
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15:54 < kanzure> .title https://news.ycombinator.com/item?id=16079735n
15:54 < yoleaux> kanzure: Sorry, that doesn't appear to be an HTML page.
15:55 < kanzure> "The article complains that the Stanford team is biased because they are not using sequences to represent the molecular structures. But this actually makes a lot of sense because molecular structures are graphs. The article then goes on to say that the Stanford team has an agenda to get everyone to use deepchem instead of TensorFlow or PyTorch. But TensorFlow is a dependency in deepchem, and ...
15:55 < kanzure> ...deepchem looks like a bunch of useful tools wrapped around TensorFlow."n
15:55 < kanzure> .title https://news.ycombinator.com/item?id=16079735
15:55 < yoleaux> AI in drug discovery is overhyped: examples from AstraZeneca, Harvard, Stanford | Hacker News
15:56 < kanzure> .title https://arxiv.org/abs/1706.06689
15:56 < yoleaux> [1706.06689] Chemception: A Deep Neural Network with Minimal Chemistry Knowledge Matches the Performance of Expert-developed QSAR/QSPR Models
15:56 < kanzure> .title https://arxiv.org/abs/1712.02734
15:56 < yoleaux> [1712.02734] ChemNet: A Transferable and Generalizable Deep Neural Network for Small-Molecule Property Prediction
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16:19 < kanzure> "Observation of current-induced, long-lived persistent spin polarization in a topological insulator: A rechargeable spin battery" http://advances.sciencemag.org/content/3/4/e1602531
16:22 < kanzure> "Machine learning in materials informatics: recent applications and prospects" https://www.nature.com/articles/s41524-017-0056-5
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16:48 < kanzure> http://www.andreykurenkov.com/writing/a-brief-history-of-neural-nets-and-deep-learning/
16:48 < kanzure> http://www.andreykurenkov.com/writing/a-brief-history-of-neural-nets-and-deep-learning-part-2/
16:48 < kanzure> http://www.andreykurenkov.com/writing/a-brief-history-of-neural-nets-and-deep-learning-part-3/
16:48 < kanzure> http://www.andreykurenkov.com/writing/a-brief-history-of-neural-nets-and-deep-learning-part-4/
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17:35 < kanzure> testicular organoids https://link.springer.com/protocol/10.1007/7651_2017_48
17:35 < kanzure> http://www.cell.com/stem-cell-reports/abstract/S2213-6711(16)30274-0
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18:00 < kanzure> "The poor take-up of sperm banks offering “superior” sperm, she says, already shows that. For most women, “the emotional significance of reproduction outweighs any notion of ‘optimisation’”. Charo feels that “our ability to love one another with all our imperfections and foibles outweighs any notion of ‘improving’ our children through genetics”."
18:00 < kanzure> that does not seem to factor in the idea of, uh, taking out follies... sperm banks offer *different* fathers.
18:01 < kanzure> https://www.theguardian.com/science/2017/jan/08/designer-babies-ethical-horror-waiting-to-happen
18:01 < kanzure> https://www.theguardian.com/science/2016/dec/02/kazuo-ishiguro-were-coming-close-to-the-point-where-we-can-create-people-who-are-superior-to-others
18:02 < kanzure> "we can create people who are superior to others" hooray
18:03 < kanzure> https://www.theatlantic.com/science/archive/2017/08/us-scientists-edit-human-embryos-with-crisprand-thats-okay/535668/
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18:34 < yoleaux> kanzure: make an open-source somethig something (genemods)
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18:53 < kanzure> hmm
18:54 < kanzure> yes.. right on schedule.
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19:22 < jrayhawk> brb sitting is unhealthy *goes out to smoke* *comes back to sit some more*
19:24 < kanzure> hm?
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21:59 < kanzure> .wik genetic lottery
21:59 < yoleaux> kanzure: Sorry, that command (.wik) crashed.
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22:07 < kanzure> .tw https://twitter.com/kanzure/status/949522691652046848
22:07 < yoleaux> It's unclear to me whether the genetic lottery is legal. (@kanzure)
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--- Log closed Sat Jan 06 00:00:04 2018