--- Log opened Fri Jan 19 00:00:29 2018 00:01 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap 00:05 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 00:18 -!- aeiousom1thing [~aeiousome@183.82.170.54] has joined ##hplusroadmap 00:21 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Ping timeout: 255 seconds] 00:22 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap 00:24 -!- jtimon [~quassel@41.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 00:37 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 256 seconds] 00:40 -!- emeraldgreen [~user@188.227.115.178] has joined ##hplusroadmap 00:53 -!- gnusha [~gnusha@unaffiliated/kanzure/bot/gnusha] has joined ##hplusroadmap 00:53 -!- Topic for ##hplusroadmap: biohacking, nootropics, transhumanism, open hardware | as investigated by the fbi weapons of mass destruction division | this channel is LOGGED: http://gnusha.org/logs | http://diyhpl.us/wiki | "ray kurzweil is a pessimist" - george church 00:53 -!- Topic set by kanzure [~kanzure@unaffiliated/kanzure] [Tue Aug 29 14:28:52 2017] 00:53 [Users ##hplusroadmap] 00:53 [ adlai ] [ ebowden ] [ juul ] [ Qfwfq ] 00:53 [ aeiousom1thing ] [ eleitl ] [ kanzure ] [ rancyd ] 00:53 [ AgenttiX ] [ emeraldgreen ] [ kuldeep ] [ rancyd_ ] 00:53 [ andytoshi ] [ EnabrinTain ] [ maaku ] [ razzy ] 00:53 [ anonnumberanon ] [ ensign ] [ Madars ] [ red-001 ] 00:53 [ archels ] [ entity8421[m] ] [ Malvolio ] [ redlegion] 00:53 [ Avian-Anathema ] [ ExeciN ] [ mf1008 ] [ rk[ghost]] 00:53 [ balrog ] [ FourFire ] [ mgxm ] [ s0ph1a ] 00:53 [ bbrittain ] [ gnusha ] [ midnightmagic] [ sachy ] 00:53 [ berndj ] [ gwillen ] [ mrdata ] [ sandeepkr] 00:53 [ bkero ] [ heath ] [ Mrkva ] [ saturn2 ] 00:53 [ BobaMa ] [ helleshin ] [ nanotube ] [ saurik ] 00:53 [ brujo_biologica] [ HEx1 ] [ nickjohnson ] [ sivoais ] 00:53 [ bsm117532 ] [ Hooloovo0 ] [ night ] [ streety ] 00:53 [ Burninate ] [ indiebio_ ] [ nmz787 ] [ superkuh ] 00:53 [ caraka ] [ Iriez ] [ nsh ] [ Taek ] 00:53 [ catern ] [ JayDugger ] [ pasky ] [ thundara_] 00:53 [ cloudcell ] [ Jenda` ] [ pepesza ] [ TMA ] 00:53 [ Cory ] [ Joshchamp_ ] [ pompolic ] [ y0no ] 00:53 [ docl ] [ jrayhawk ] [ poppingtonic ] [ yoleaux ] 00:53 [ Douhet ] [ jtimon ] [ potatope ] 00:53 [ drewbot ] [ juri_ ] [ preview ] 00:53 [ dustinm- ] [ justan0theruser] [ Proteus_ ] 00:53 -!- Irssi: ##hplusroadmap: Total of 89 nicks [0 ops, 0 halfops, 0 voices, 89 normal] 00:53 -!- Channel ##hplusroadmap created Thu Feb 25 23:40:30 2010 00:53 -!- Irssi: Join to ##hplusroadmap was synced in 12 secs 00:53 -!- fenn [~fenn@unaffiliated/fenn] has joined ##hplusroadmap 00:59 -!- preview [~quassel@2407:7000:842d:4054:d5cf:344e:df10:15a2] has quit [Ping timeout: 276 seconds] 01:05 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 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host closed the connection] 03:32 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 03:48 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 03:50 -!- nicedice [~nicedice@unaffiliated/nicedice] has joined ##hplusroadmap 03:58 -!- nicedice [~nicedice@unaffiliated/nicedice] has quit [Quit: Leaving] 04:06 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 04:09 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-qoqpubxoidhjqxkf] has joined ##hplusroadmap 04:26 -!- balrog [~balrog@unaffiliated/balrog] has quit [Ping timeout: 248 seconds] 04:27 -!- midnightmagic [~midnightm@unaffiliated/midnightmagic] has quit [Ping timeout: 248 seconds] 04:27 -!- Proteus_ [~proteus@unaffiliated/proteus] has quit [Ping timeout: 248 seconds] 04:27 -!- andytoshi [~apoelstra@unaffiliated/andytoshi] has quit [Ping timeout: 248 seconds] 04:28 -!- midnightmagic [~midnightm@unaffiliated/midnightmagic] has joined ##hplusroadmap 04:28 -!- balrog [~balrog@unaffiliated/balrog] has joined ##hplusroadmap 04:29 -!- andytoshi [~apoelstra@wpsoftware.net] has joined ##hplusroadmap 04:29 -!- Proteus_ [~proteus@unaffiliated/proteus] has joined ##hplusroadmap 04:33 -!- dstrbd_ [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 04:33 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Ping timeout: 276 seconds] 04:34 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has joined ##hplusroadmap 04:45 < kanzure> someone wants an exclusive agreement for my designer bay work O_o 04:46 < kanzure> seems a little premature to... wait. premature. heh. 04:47 < kanzure> "Mechanogenetics for the remote and noninvasive control of cancer immunotherapy" http://www.pnas.org/content/early/2018/01/11/1714900115.abstract 04:48 -!- jtimon [~quassel@41.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 04:48 < kanzure> "There is a lack of a general method to noninvasively and remotely manipulate cells with high spatiotemporal precisions. We developed an ultrasound-based mechanogenetics system to achieve this goal. Cells were engineered with the mechanosensor Piezo1 and genetic transducing modules to perceive the mechanical perturbation generated by the ultrasound wave and transduce it into genetic ... 04:48 < kanzure> ...activities. Mechanosensitive and ultrasound-controllable T cells were further engineered to target and eradicate tumor cells with inducible chimeric antigen receptors. This mechanogenetics approach can be extended to remotely control, in principle, any gene activity in live cells for the reprogramming of cellular functions. This method should also provide a general approach to remotely ... 04:48 < kanzure> ...control molecular functions for biological studies and clinical applications, particularly cell-based cancer immunotherapy." 04:48 < kanzure> why not just use the same ultrasound emitters to ablate the tumor? 05:01 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap 05:20 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 06:11 -!- DataPacRat [~dan@adsl-122.itcanada.com] has joined ##hplusroadmap 06:13 -!- dstrbd_ [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Remote host closed the connection] 06:14 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 06:20 -!- dstrbd_ [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 06:21 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Read error: Connection reset by peer] 06:24 -!- dstrbd_ 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dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 07:41 -!- eudoxia [~eudoxia@190.99.101.24] has joined ##hplusroadmap 07:58 < kanzure> hyper blort 1 07:58 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 08:05 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection] 08:19 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Read error: Connection reset by peer] 08:21 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 08:22 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Remote host closed the connection] 08:24 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 08:32 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Read error: Connection reset by peer] 08:32 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 08:41 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10:33 < JayDugger> Only counts as "hyper" if you have a matching key. 10:42 -!- m4l3z [~m4l3z@2a01cb040226f200e403c867db07f8b7.ipv6.abo.wanadoo.fr] has quit [Quit: Leaving] 10:44 < kanzure> https://www.youtube.com/watch?v=aY4q4VUfN-I 10:45 -!- DataPacRat [~dan@adsl-122.itcanada.com] has quit [Ping timeout: 240 seconds] 10:49 -!- jaboja [~jaboja@jaboja.pl] has joined ##hplusroadmap 10:49 -!- rk[ghost] [~rak@cpe-66-61-32-99.neo.res.rr.com] has quit [Ping timeout: 265 seconds] 11:00 -!- jtimon [~quassel@41.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 11:18 -!- emeraldgreen [~user@ip-185-18-126-190.spb.avantel.ru] has quit [Quit: Leaving.] 11:31 -!- namespace [user@2600:3c02::f03c:91ff:fe7b:227f] has joined ##hplusroadmap 11:41 -!- jaboja [~jaboja@jaboja.pl] has quit [Ping timeout: 248 seconds] 11:41 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 256 seconds] 12:12 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 12:18 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 268 seconds] 12:19 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 12:32 -!- eudoxia [~eudoxia@190.99.101.24] has quit [Remote host closed the connection] 12:39 -!- razzy` [~user@static-84-242-120-106.net.upcbroadband.cz] has joined ##hplusroadmap 12:53 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Quit: dstrbd] 13:08 < nmz787> darsie: I work at the company who makes the HD Rosetta stuff... in case you are further interested or want some work done 13:09 < nmz787> kanzure: you have designer baby work? 13:11 < kanzure> thought you saw the proposal 13:18 < darsie> nmz787: cool :) 13:20 < darsie> nmz787: Well, I want to upload my mind and so cryopreserve it till the scanning tech is ready. So I thought of a cryo facility which should run autonomously for up to 1000 years and I might need to store some software for that. But I guess 100 years is long enough, so more mundane storage would do. 13:23 < darsie> nmz787: How much is a disk and how many bytes can you store readable with a "simple" microscope. 13:24 < darsie> Why don't they mention data storage? 13:24 < darsie> Like, binary. 13:26 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has joined ##hplusroadmap 14:01 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 256 seconds] 14:02 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 256 seconds] 14:25 < nmz787> darsie: they've never done any binary data storage, but a rough estimate would be about 4 GB in 3 to 6 days of write time, but that's using 20nm pixels which is well below "simple" microscope 14:29 < darsie> thx 14:53 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 255 seconds] 15:25 -!- DataPacRat [~dan@adsl-122.itcanada.com] has joined ##hplusroadmap 15:53 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has quit [Ping timeout: 240 seconds] 16:47 < kanzure> remote: error: cannot lock ref 'HEAD': Unable to create '/srv/git/diyhpluswiki.git/HEAD.lock': Permission denied 16:47 < kanzure> jrayhawk: ^ 16:49 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has joined ##hplusroadmap 17:16 -!- augur [~augur@192.195.83.130] has joined ##hplusroadmap 17:36 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 256 seconds] 17:43 < jrayhawk> ugh 17:44 < kanzure> what'd i do? 17:45 < jrayhawk> I forgot to hold that package. 17:45 < jrayhawk> Oh hey, there's security advisories to care about on this downgrade. 17:45 < jrayhawk> Try again? 17:46 < jrayhawk> i wonder if i should learn C just to fix that 17:49 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=bd700e64 Bryan Bishop: transcript: mimblewimble and scriptless scripts (2018) >> http://diyhpl.us/diyhpluswiki/transcripts/realworldcrypto/2018/mimblewimble-and-scriptless-scripts/ 17:51 < kanzure> thank you 17:52 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e859eda7 Bryan Bishop: tweeter link >> http://diyhpl.us/diyhpluswiki/transcripts/realworldcrypto/2018/mimblewimble-and-scriptless-scripts/ 17:53 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has joined ##hplusroadmap 18:18 -!- augur [~augur@192.195.83.130] has quit [Ping timeout: 264 seconds] 18:21 -!- strages [uid11297@gateway/web/irccloud.com/x-ppokvabxicawjabf] has joined ##hplusroadmap 18:25 -!- augur [~augur@192.195.83.130] has joined ##hplusroadmap 19:11 -!- emeraldgreen [~user@188.227.115.178] has joined ##hplusroadmap 19:27 -!- drewbot [~cinch@54.226.121.51] has quit [Remote host closed the connection] 19:29 < JayDugger> Thanks for the transcript. 19:34 -!- ebowden_ [~ebowden@101.180.202.22] has joined ##hplusroadmap 19:38 -!- ebowden [~ebowden@2001:8003:103f:8600:3953:760:75c:1349] has quit [Ping timeout: 265 seconds] 19:58 -!- augur [~augur@192.195.83.130] has quit [Remote host closed the connection] 19:59 -!- augur [~augur@192.195.83.130] has joined ##hplusroadmap 20:03 -!- augur [~augur@192.195.83.130] has quit [Ping timeout: 264 seconds] 20:14 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 20:39 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Quit: dstrbd] 21:07 < andytoshi> awesome transcript, thanks! 21:22 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 21:26 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 260 seconds] 21:37 -!- DataPacRat [~dan@adsl-122.itcanada.com] has quit [Ping timeout: 240 seconds] 21:41 -!- rk[ghost] [~rak@cpe-66-61-32-99.neo.res.rr.com] has joined ##hplusroadmap 21:52 -!- DataPacRat [~dan@adsl-137.itcanada.com] has joined ##hplusroadmap 22:08 -!- preview [~quassel@2407:7000:842d:4054:d5cf:344e:df10:15a2] has quit [Read error: Connection reset by peer] 22:46 -!- DataPacRat [~dan@adsl-137.itcanada.com] has quit [Ping timeout: 248 seconds] 22:54 -!- sivoais [~zaki@unaffiliated/sivoais] has quit [Ping timeout: 260 seconds] 23:01 -!- DataPacRat [~dan@vdsl-54.itcanada.com] has joined ##hplusroadmap 23:03 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: SCIENTISTS PREDICT ICE AGE] 23:04 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 23:08 -!- emeraldgreen [~user@188.227.115.178] has quit [Quit: Leaving.] 23:18 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 23:56 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 260 seconds] --- Log closed Sat Jan 20 00:00:28 2018