--- Log opened Fri Mar 30 00:00:33 2018 01:05 -!- jtimon [~quassel@142.29.134.37.dynamic.jazztel.es] has quit [Ping timeout: 260 seconds] 01:09 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 01:25 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap 01:32 -!- wrldpc1 [~ben@hccd37dc13f.bai.ne.jp] has quit [Quit: wrldpc1] 01:33 * adlai suspects many lazibois who believe that the universe is a simulation, have given up on recursion; others, such as I, take the long view in which silicon is merely the second nuclear cancer. 01:36 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Ping timeout: 240 seconds] 02:24 -!- red-001 [red@gateway/shell/elitebnc/x-bkwshxjrmhwfoygb] has quit [Ping timeout: 264 seconds] 02:31 -!- Gurkenglas_ [~Gurkengla@dslb-188-103-223-018.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 02:38 -!- red-001 [red@gateway/shell/elitebnc/x-iphzmkgvdazzmoow] has joined ##hplusroadmap 03:44 -!- wrldpc1 [~ben@hccd37dc13f.bai.ne.jp] has joined ##hplusroadmap 03:52 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 03:55 -!- wrldpc1 [~ben@hccd37dc13f.bai.ne.jp] has quit [Quit: wrldpc1] 03:56 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 256 seconds] 04:32 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has joined ##hplusroadmap 05:22 -!- gabbar1947 [uid205515@gateway/web/irccloud.com/x-wuaaakzqcmfiimhv] has joined ##hplusroadmap 05:23 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 05:28 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 248 seconds] 05:36 -!- aeiousomething [~aeiousome@124.123.14.99] has quit [Ping timeout: 260 seconds] 06:13 < archels> https://i.imgur.com/Q0I8zap.gifv 06:33 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 268 seconds] 07:37 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has quit [Quit: Leaving] 07:40 < kanzure> blort 07:51 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has joined ##hplusroadmap 08:03 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has quit [Quit: Leaving] 08:20 -!- WeirdTolkienishF [~Weird@204.48.46.11] has joined ##hplusroadmap 08:20 -!- WeirdTolkienishF [~Weird@204.48.46.11] has quit [Changing host] 08:20 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has joined ##hplusroadmap 08:22 < kanzure> .tw https://twitter.com/albertcardona/status/979056639687962624 08:22 < yoleaux> That lung fish have potentially a 3-layered cortex means that the cerebral cortex likely existed already over 400 million years ago (that's close to the Cambrian explosion), and has been evolving ever since. https://en.wikipedia.org/wiki/Lungfish https://pbs.twimg.com/media/DZZOf5vX0AA6kYC.jpg (@albertcardona, in reply to tw:979035886204739584) 08:27 < kanzure> "Cameo: A python library for computer aided metabolic engineering and optimization of cell factories" https://pubs.acs.org/doi/10.1021/acssynbio.7b00423 https://twitter.com/DrLeoRios/status/976556923498704897 08:27 < kanzure> http://try.cameo.bio/ 08:28 < kanzure> "Cell-free approaches in synthetic biology utilizing microfluidics" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867865/ 08:30 < kanzure> "Chemical communication between bacteria and cell-free gene expression systems within linear chains of emulsion droplets" http://pubs.rsc.org/en/Content/ArticleLanding/2016/IB/C5IB00301F https://twitter.com/jimhaseloff/status/970357333841928194 08:47 -!- cpc26 [~cpc26@104-185-77-31.lightspeed.rlghnc.sbcglobal.net] has joined ##hplusroadmap 08:47 -!- cpc26 [~cpc26@104-185-77-31.lightspeed.rlghnc.sbcglobal.net] has quit [Changing host] 08:47 -!- cpc26 [~cpc26@fsf/member/cpc26] has joined ##hplusroadmap 08:51 -!- cpc26 [~cpc26@fsf/member/cpc26] has quit [Client Quit] 09:28 -!- cpc26_ [~cpc26@2600:1700:f90:4320:79da:30a0:a28f:a37b] has joined ##hplusroadmap 09:33 -!- cpc26_ [~cpc26@2600:1700:f90:4320:79da:30a0:a28f:a37b] has quit [Client Quit] 09:42 -!- cpc26 [~cpc26@2600:1700:f90:4320:7c66:42c4:6466:3eda] has joined ##hplusroadmap 09:42 -!- cpc26 [~cpc26@2600:1700:f90:4320:7c66:42c4:6466:3eda] has quit [Changing host] 09:42 -!- cpc26 [~cpc26@fsf/member/cpc26] has joined ##hplusroadmap 09:45 -!- bsm117532 [~mcelrath@173-9-124-61-NewEngland.hfc.comcastbusiness.net] has joined ##hplusroadmap 10:18 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:9c4d:9fb6:d795:18f7] has joined ##hplusroadmap 10:40 -!- jtimon [~quassel@142.29.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 11:05 -!- mrdata_ [~mrdata@unaffiliated/mrdata] has joined ##hplusroadmap 11:07 -!- mrdata [~mrdata@unaffiliated/mrdata] has quit [Ping timeout: 248 seconds] 11:12 * nmz787 re-arranged my garage last night to get a bit closer to attempting to setup FIB 11:14 < kanzure> ever hear of the tragedy of the yak shaver? 11:14 -!- ebowden [~ebowden@2001:8003:103d:2e00:2d6c:4bc5:b9b7:3c9e] has quit [Ping timeout: 260 seconds] 11:14 < nmz787> I know of yak shaving 11:14 < nmz787> not sure i've heard of 'the tragedy' 11:15 < kanzure> well it ought to be a tragedy 11:15 < nmz787> I was thinking I might send my tax return towards construction of a garage-extension 11:16 < nmz787> err, s/return/refund/ 11:18 -!- mrdata_ is now known as mrdata 11:41 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 12:22 -!- void3301 is now known as voidnullvoid3301 12:22 -!- voidnullvoid3301 is now known as void3301 12:25 -!- aeiousomething [~aeiousome@124.123.14.99] has joined ##hplusroadmap 13:00 < kanzure> "Planning chemical syntheses with deep neural networks and symbolic AI" https://www.nature.com/articles/nature25978 13:06 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 13:16 -!- Gurkenglas_ is now known as Gurkengla 13:17 -!- Gurkengla is now known as Gurkenglas 13:40 -!- aeiousomething [~aeiousome@124.123.14.99] has quit [Ping timeout: 255 seconds] 14:25 < kanzure> "... and a filter network to pre-select the most promising retrosynthetic steps. These deep neural networks were trained on essentially all reactions ever published in organic chemistry" 14:25 < kanzure> hmm but what details does it have about each of the organic chemistry reactions? 14:31 < kanzure> follow-up on the frenzy of crispr-cas9 papers about off-target effects https://gizmodo.com/the-scientists-who-sparked-crispr-panic-couldnt-reprodu-1824181703 14:35 < kanzure> .tw https://twitter.com/antonioregalado/status/979353046789640192 14:35 < yoleaux> USDA has no plans to regulate CRISPR plants (thread). So long as the plant reate with gene editing *could* have been arrived at with breeding, no regulation. Big day for plant engineers. Statement from the USDA Sect Purdue https://www.usda.gov/media/press-releases/2018/03/28/secretary-perdue-issues-usda-statement-plant-breeding-innovation (@antonioregalado) 14:41 < Douhet> kanzure, that's awesome 14:41 -!- Gurkenglas [~Gurkengla@dslb-188-103-223-018.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 14:44 < kanzure> classroom thing https://www.skypeascientist.com/ 15:34 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 15:38 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 256 seconds] 15:50 < kanzure> not sure how to think about this https://en.wikipedia.org/wiki/Net_capital_rule something about assuming all positions should be liquid.. and that liabilities can only be paid in dollars? 16:29 -!- Gurkenglas [~Gurkengla@dslb-188-103-223-018.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 16:35 -!- wrldpc1 [~ben@hcccbcac120.bai.ne.jp] has joined ##hplusroadmap 17:02 < kanzure> why don't open-source software licenses have stronger requirements about reputational reporting (e.g. reporting where the software is being used as a license condition) 17:03 -!- wrldpc1 [~ben@hcccbcac120.bai.ne.jp] has quit [Quit: wrldpc1] 17:05 -!- wrldpc1 [~ben@hcccbcac120.bai.ne.jp] has joined ##hplusroadmap 17:25 < kanzure> "Investigating the benefits of automated negotiations in enhancing people's negotiation skills" https://pdfs.semanticscholar.org/92a7/8a7fb0ed81cb4597562496b14379666c03f6.pdf 17:35 -!- wrldpc1 [~ben@hcccbcac120.bai.ne.jp] has quit [Quit: wrldpc1] 17:36 -!- drewbot [~cinch@54.81.78.2] has quit [Remote host closed the connection] 17:51 -!- gabbar1947 [uid205515@gateway/web/irccloud.com/x-wuaaakzqcmfiimhv] has quit [Quit: Connection closed for inactivity] 18:14 -!- CaptHindsight [~2020@unaffiliated/capthindsight] has quit [Ping timeout: 255 seconds] 18:18 < kanzure> "Unified pragmatic models for generating and following instructions" https://arxiv.org/pdf/1711.04987.pdf 18:30 -!- CaptHindsight [~2020@c-73-208-96-129.hsd1.il.comcast.net] has joined ##hplusroadmap 18:30 -!- CaptHindsight [~2020@c-73-208-96-129.hsd1.il.comcast.net] has quit [Changing host] 18:30 -!- CaptHindsight [~2020@unaffiliated/capthindsight] has joined ##hplusroadmap 18:52 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds] 19:00 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 19:04 -!- Guest59512 [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 256 seconds] 19:17 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 19:39 < fenn> wow, an actual win for genetic engineering 20:02 -!- balrog [~balrog@unaffiliated/balrog] has quit [Quit: Bye] 20:11 -!- balrog [~balrog@unaffiliated/balrog] has joined ##hplusroadmap 20:22 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined 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[~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 21:28 -!- jtimon [~quassel@142.29.134.37.dynamic.jazztel.es] has quit [Ping timeout: 264 seconds] 21:47 -!- ebowden [~ebowden@2001:8003:103d:2e00:bc55:66e2:4c68:57f6] has quit [Ping timeout: 260 seconds] 21:55 -!- ebowden [~ebowden@2001:8003:103d:2e00:bc55:66e2:4c68:57f6] has joined ##hplusroadmap 22:25 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 22:36 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 22:38 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 268 seconds] 22:41 -!- aeiousomething [~aeiousome@124.123.14.99] has quit [Ping timeout: 240 seconds] 22:44 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: ICE AGE NEAR, SCIENTISTS WARN] 22:44 -!- aeiousomething [~aeiousome@124.123.14.99] has joined ##hplusroadmap 23:16 < kanzure> hmph 23:26 -!- ebowden 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