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justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 05:54 < kanzure> .tw https://twitter.com/melanie_matheu/status/1009815147441844224 05:54 < yoleaux> Prellis Biologics aims to 3D print kidney vessels in 12 hours or less https://3dprintingindustry.com/news/prellis-biologics-aims-to-3d-print-kidney-vessels-in-12-hours-or-less-134947/?utm_source=twitter&utm_medium=social&utm_campaign=social-pug (@melanie_matheu) 05:55 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Read error: Connection reset by peer] 05:57 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 06:00 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Read error: Connection reset by peer] 06:02 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 06:03 -!- lewl [~lewl@ip-173-153-71-31.ekrgmd.spcsdns.net] has quit [Ping timeout: 268 seconds] 06:05 -!- jqtrde 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[~sektor@95.87.234.241] has joined ##hplusroadmap 13:03 -!- bluebear_ [~dluhos@80.95.97.194] has quit [Quit: Leaving.] 13:03 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 13:25 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 13:31 -!- Storyteller [~Storytell@unaffiliated/storyteller] has joined ##hplusroadmap 13:32 -!- Storyteller [~Storytell@unaffiliated/storyteller] has quit [Remote host closed the connection] 13:35 < nmz787> hmm, $150 for a 48" square HEPA filter and fan unit from a cleanroom ceiling 13:35 < nmz787> throw some sides on that and I'd have a laminar flow hood 13:38 < nmz787> anyone have any opinions against doing something like that? other than this thing would require a hefty amount of space (I was thinking of using it horiontally, though it was designed for vertical use) https://www.ebay.com/itm/DAW-TECHNOLOGIES-277-VAC-FFU-with-LAMINAR-FLOW-HEPA-FILTER-and-FAN-UNIT-47-1-8/322248760685 13:40 < nmz787> I was also eyeing these small chinese units, but it seems getting replacement filters is unheard of and seems pretty sketchy https://www.amazon.com/Mophorn-0-25-0-45m-Velocity-Laboratory-Horizontal/dp/B072LLK35Y/ref=sr_1_2?ie=UTF8&qid=1529656294&sr=8-2&keywords=hd-650+filter#customerReviews 13:53 -!- lewl [~lewl@pool-108-18-151-95.washdc.fios.verizon.net] has quit [Remote host closed the connection] 13:54 -!- lewl [~lewl@pool-108-18-151-95.washdc.fios.verizon.net] has joined ##hplusroadmap 13:59 -!- lewl [~lewl@pool-108-18-151-95.washdc.fios.verizon.net] has quit [Ping timeout: 256 seconds] 14:13 -!- vurtz [~vurtz@2a02:c7d:ba9:9b00:3d91:4b8f:f25:1c69] has quit [Ping timeout: 256 seconds] 14:20 -!- lewl [~lewl@pool-108-18-151-95.washdc.fios.verizon.net] has joined ##hplusroadmap 15:07 -!- drewbot [~cinch@54.205.131.214] has joined ##hplusroadmap 15:13 -!- bird_hops [~bird_hops@78-11-233-153.static.ip.netia.com.pl] has quit [Ping timeout: 248 seconds] 15:30 -!- lewl 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has joined ##hplusroadmap 19:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Remote host closed the connection] 19:55 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 20:00 < kanzure> hmph 20:07 < kanzure> .wik height and intelligence 20:07 < yoleaux> "The study of height and intelligence examines correlations between height and human intelligence. Some epidemiological research on the subject has shown that there is a small but statistically significant positive correlation between height and intelligence after controlling for socioeconomic class and parental education." — https://en.wikipedia.org/wiki/Height_and_intelligence 20:08 < l_wl_> And whats the relationship yoleaux 20:08 < kanzure> "Brain structure mediates the association between height and cognitive ability" https://www.biorxiv.org/content/early/2017/09/01/183525 https://www.sciencedaily.com/releases/2018/05/180514095539.htm 20:08 < l_wl_> Seems far more to due with secondary effects 20:08 < l_wl_> That height n shortness bring 20:17 -!- preview [~quassel@2407:7000:8423:b00::2] has quit [Ping timeout: 276 seconds] 20:31 < kanzure> alright are we generally sure about brain encephalization and increase in surface area as being generally smart things to go and do? 20:32 < kanzure> because i think you could do optogenetics (or anything else in a feedback loop) during in utero development to cause more encephalization and sulcri development 20:32 < kanzure> even if we don't know the actual polygenic contributions of different genes to typical encephalization 20:33 < kanzure> this is based on the concept that much of the adult body is planned during in utero development, so if you can temporarily influence in utero development then you should have a reasonably strong effect as if you knew all the umpteen thousand genes to modify to cause height or intelligence traits 20:35 < kanzure> also, while "more neurons == more smarterer" might not be generally true for human brain, it may true for certain types of neurons or certain areas of the brain 20:36 < kanzure> .wik encephalization quotient 20:36 < yoleaux> "Encephalization quotient (EQ) or encephalization level is a relative brain size measure that is defined as the ratio between actual brain mass and predicted brain mass for an animal of a given size, which may approximate intelligence level or cognition of the species." — https://en.wikipedia.org/wiki/Encephalization_quotient 20:37 < kanzure> oh that's not what i wanted. O_O. i thought it was a brain surface area to.. mass.. or something.. 20:37 < kanzure> sulcri-ization. i thought there was a word for that? 20:40 < kanzure> re: brain region specific overgrowth, at a lower resolution things like GRIN2B overexpression and tet-regulated NMDA receptor overexpression have been proposed to enhance learning 20:40 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 20:42 -!- preview [~quassel@2407:7000:8423:b00::2] has joined ##hplusroadmap 20:52 < nmz787> kanzure: well I guess it depends on how lasting the prenatal brain structure is... google says infants are born with 28% final max brain volume in adulthood 20:52 < nmz787> does it just expand during that time, or is it all sort of reconfiguring? 21:01 < kanzure> eh someone has probably studied this with in utero electroporation 21:05 < kanzure> .wik bone morphogenetic protein 21:05 < yoleaux> "Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body." — https://en.wikipedia.org/wiki/Bone_morphogenetic_protein 21:10 < nmz787> https://jamanetwork.com/journals/jamaneurology/fullarticle/1893442 21:10 < nmz787> .title 21:10 < yoleaux> Structural Growth Trajectories and Rates of Change in the First 3 Months of Infant Brain Development | Child Development | JAMA Neurology | JAMA Network 21:11 < nmz787> "The growth rate was approximately 1%/d, slowing to 0.4%/d by the end of the first 3 months, when the brain reached just more than half of elderly adult brain volume." 21:13 < kanzure> "Neuronal factors determining high intelligence" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685590/ 21:13 < kanzure> yeah but which parts grew and which didn't; i bet the plan was already set in motion by in utero development, not so much by genetics. 21:15 < kanzure> "Hippocampal volumes and neuron numbers increase along a gradient of environmental harshness: a large-scale comparison" http://rspb.royalsocietypublishing.org/content/276/1656/401 21:16 < kanzure> this 2004 study says hippocampus volume is not strongly correlated with superior memory https://www.ncbi.nlm.nih.gov/pubmed/15193947 21:19 < kanzure> "Hippocampal size positively correlates with verbal IQ in male children" https://onlinelibrary.wiley.com/doi/pdf/10.1002/hipo.20282 21:20 -!- preview [~quassel@2407:7000:8423:b00::2] has quit [Ping timeout: 255 seconds] 21:21 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Remote host closed the connection] 21:21 < kanzure> "Hippocampal (subfield) volume and shape in relation to cognitive performance across the adult lifespan" https://onlinelibrary.wiley.com/doi/abs/10.1002/hbm.22825 21:21 < kanzure> ... 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[~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 22:21 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Read error: Connection reset by peer] 22:23 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Remote host closed the connection] 22:23 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 22:23 < mrdata> lewl, please stop joining and quitting every couple minutes thanks 22:23 -!- lewl [~lewl@pool-173-66-205-23.washdc.fios.verizon.net] has quit [Read error: Connection reset by peer] 22:23 < l_wl_> I am? 22:23 < mrdata> YES 22:23 < l_wl_> Is it my ping? 22:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 22:24 < mrdata> i'm getting a wall of join/part messages from you 22:24 -!- l_wl_ [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has left ##hplusroadmap ["gone for now but not for good"] 22:26 -!- l_wl [~l_wl@pool-173-66-205-23.washdc.fios.verizon.net] has joined ##hplusroadmap 22:26 < l_wl> Has it stopped now? 22:28 < mrdata> hang on, i'll know in a few minutes 22:28 < l_wl> Ty it may have been my phone (sorry to distract) 22:30 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 240 seconds] 22:30 < l_wl> Also it seems that there are no good open source solutions for those who have hearing issues. They are confined to a small selection of hearing aids (that are implanted) and whats worse then those hearing aids only process sound using their own softwear 22:36 < mrdata> l_wl, seems to have stopped; thanks 22:45 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:31fb:bb59:abc5:961d] has quit [Quit: Leaving] 23:01 -!- ebowden [~ebowden@2001:8003:1065:c600:8001:c509:3b79:5254] has quit [Remote host closed the connection] 23:43 -!- ebowden [~ebowden@2001:8003:1014:2500:943b:8cb4:ba54:6ca4] has joined ##hplusroadmap 23:57 -!- ebowden [~ebowden@2001:8003:1014:2500:943b:8cb4:ba54:6ca4] has quit [Remote host closed the connection] 23:57 -!- ebowden_ [~ebowden@124.183.192.230] has joined ##hplusroadmap --- Log closed Sat Jun 23 00:00:54 2018