--- Log opened Wed Jul 11 00:00:13 2018 00:06 -!- l_wl [~l_wl@2606:6000:6087:f00:de2:3ff0:1e53:b3f7] has joined ##hplusroadmap 00:38 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 01:10 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap 01:20 -!- l_wl [~l_wl@2606:6000:6087:f00:de2:3ff0:1e53:b3f7] has quit [Remote host closed the connection] 01:25 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Remote host closed the connection] 01:25 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap 02:00 -!- l_wl [~l_wl@2606:6000:6087:f00:f935:5afd:cc96:2c7c] has joined ##hplusroadmap 02:05 -!- l_wl [~l_wl@2606:6000:6087:f00:f935:5afd:cc96:2c7c] has quit [Ping timeout: 276 seconds] 02:06 -!- ShaKata [~ShaKata@77.139.218.69] has joined ##hplusroadmap 02:29 -!- ShaKata [~ShaKata@77.139.218.69] has quit [Ping timeout: 260 seconds] 02:48 -!- lewlking [~lewlking@2606:6000:6087:f00:7c11:69bb:2896:2427] has joined ##hplusroadmap 02:48 -!- l_wl [~l_wl@2606:6000:6087:f00:7c11:69bb:2896:2427] has joined ##hplusroadmap 02:49 -!- l_wl [~l_wl@2606:6000:6087:f00:7c11:69bb:2896:2427] has quit [Client Quit] 02:51 -!- lewlking [~lewlking@2606:6000:6087:f00:7c11:69bb:2896:2427] has quit [Client Quit] 02:54 -!- l_wl [~l_wl@2606:6000:6087:f00:84b0:3566:7196:751] has joined ##hplusroadmap 02:59 -!- l_wl [~l_wl@2606:6000:6087:f00:84b0:3566:7196:751] has quit [Ping timeout: 276 seconds] 03:11 -!- jtimon [~quassel@40.28.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 03:20 -!- bluebear_ [~dluhos@80.95.97.194] has joined ##hplusroadmap 03:34 -!- jtimon [~quassel@40.28.134.37.dynamic.jazztel.es] has quit [Read error: Connection reset by peer] 03:38 -!- FourFire [~FourFire@234.103.189.109.customer.cdi.no] has joined ##hplusroadmap 03:39 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Remote host closed the connection] 03:39 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap 03:44 -!- Malvolio is now known as Guest84986 03:44 -!- Guest84986 [~Malvolio@unaffiliated/malvolio] has quit [Killed (verne.freenode.net (Nickname regained by services))] 03:45 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 03:45 -!- ShaKata [~ShaKata@77.139.218.69] has joined ##hplusroadmap 03:53 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Ping timeout: 244 seconds] 04:17 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap 04:25 -!- ShaKata [~ShaKata@77.139.218.69] has quit [Quit: Leaving] 04:25 -!- ShaKata [~ShaKata@77.139.218.69] has joined ##hplusroadmap 04:30 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-zyzoynoeyldtbrsz] has joined ##hplusroadmap 05:56 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 260 seconds] 06:00 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 06:36 < kanzure> blort 06:52 < kanzure> .tw https://twitter.com/schneierblog/status/1016650967834488833 06:52 < yoleaux> Recovering Keyboard Inputs through Thermal Imaging https://www.schneier.com/blog/archives/2018/07/recovering_keyb.html (@schneierblog) 07:01 < kanzure> "is bitcoin as bad as "trading harvested baby brains," as Charlie Munger says?" hmm 07:05 -!- l_wl [~l_wl@206.181.83.18] has joined ##hplusroadmap 07:08 < kanzure> .tw https://twitter.com/bryan_johnson/status/1016710046288416768 07:08 < yoleaux> #2 of @osfund series: We're in the Golden Age of Information: 90% of all data was created in the past 2 yrs. But the Age has a limit: our ability to store it. @catalogdna has an unexpected solution: DNA. https://medium.com/future-literacy/beyond-the-hard-drive-encoding-data-in-dna-1d5c2bad5289 (@bryan_johnson) 07:11 < kanzure> https://singularityhub.com/2018/07/10/new-dna-synthesis-method-could-soon-build-a-genome-in-a-day/ 07:13 -!- Kacia [~kacia@95.87.234.241] has quit [Ping timeout: 240 seconds] 07:17 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 260 seconds] 07:26 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 07:40 < kanzure> "angr is a python framework for analyzing binaries. It combines both static and dynamic symbolic ("concolic") analysis, making it applicable to a variety of tasks." 08:03 -!- l_wl [~l_wl@206.181.83.18] has quit [Remote host closed the connection] 08:16 -!- ShaKata [~ShaKata@77.139.218.69] has quit [Ping timeout: 240 seconds] 08:24 -!- ShaKata [~ShaKata@77.139.218.69] has joined ##hplusroadmap 08:41 -!- strages [uid11297@gateway/web/irccloud.com/x-ocnbakfyytowgllq] has joined ##hplusroadmap 08:43 -!- ShaKata [~ShaKata@77.139.218.69] has quit [Ping timeout: 248 seconds] 08:54 < fenn> where does that "90% of all data was created in the past 2 yrs" statistic come from? 08:57 -!- ShaKata [~ShaKata@77.139.218.69] has joined ##hplusroadmap 08:58 < kanzure> from https://www.forbes.com/sites/bernardmarr/2018/05/21/how-much-data-do-we-create-every-day-the-mind-blowing-stats-everyone-should-read/#5d1f836560ba 09:00 < fenn> it's just people repeating the same thing over and over until it becomes fact 09:02 -!- l_wl [~l_wl@206.181.83.18] has joined ##hplusroadmap 09:04 -!- l_wl [~l_wl@206.181.83.18] has quit [Remote host closed the connection] 09:05 < fenn> there are 10x more tinder swipes this year than last year! checkmate atheist 09:07 < fenn> supposedly this was the first instance of the claim, however it provides no explanation and has a very narrow view of what counts as "data" (primarily online social network interactions) https://www.sintef.no/en/latest-news/big-data-for-better-or-worse/ 09:09 < fenn> it makes me feel like an old person when i have to say "no, in 2015 we had digital cameras" 09:10 < fenn> and i don't think there's _that_ much DNA sequencing data 09:11 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:2cd8:f2a2:3866:b488] has joined ##hplusroadmap 09:12 -!- ShaKata [~ShaKata@77.139.218.69] has quit [Read error: Connection reset by peer] 09:17 < archels> [ ] I hereby declare, that the intended or end use of computers and software is not related to weapons of mass destruction, missile technology, nuclear technology or for military purposes. 09:20 < fenn> the statement is worded in general? 09:21 < fenn> wow this is crazy https://www.theregister.co.uk/2018/05/16/exploding_ecig_kills/ 09:21 < fenn> the explosion fired two pieces of the vaping device into his head, causing death by "projectile wound of head." 09:22 -!- ShaKata [~ShaKata@77.139.218.69] has joined ##hplusroadmap 09:24 < fenn> i guess it had no pressure relief valve and was tightly sealed 09:29 -!- l_wl [~l_wl@206.181.83.18] has joined ##hplusroadmap 09:38 < kanzure> .botsnack 09:38 < yoleaux> :D 09:39 < fenn> you'll spoil it 09:41 -!- nicedice [~nicedice@unaffiliated/nicedice] has joined ##hplusroadmap 09:46 -!- l_wl [~l_wl@206.181.83.18] has quit [Remote host closed the connection] 09:46 -!- nicedice [~nicedice@unaffiliated/nicedice] has quit [Quit: Leaving] 09:59 -!- aeiousomething [aeiousomet@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Quit: brb] 10:19 -!- ShaKata [~ShaKata@77.139.218.69] has quit [Ping timeout: 260 seconds] 10:29 < archels> fenn: this was on an actual web form, encountered while signing up for a computer science course in Germany 10:29 < archels> it's kind of a shame that "nuclear technology" is in there 10:30 < fenn> welcome to germany 10:32 < fenn> the original intended use for computers was in fact for missile technology, so it'd be hard to answer the question honestly in any case 10:32 < archels> haha 10:32 < archels> also ironic, given that there's an experimental nuclear reactor on site here 10:57 -!- ShaKata [~ShaKata@77.139.218.69] has joined ##hplusroadmap 11:02 -!- ShaKata [~ShaKata@77.139.218.69] has quit [Ping timeout: 240 seconds] 11:07 -!- FourFire [~FourFire@234.103.189.109.customer.cdi.no] has quit [Ping timeout: 256 seconds] 11:44 -!- bluebear_ [~dluhos@80.95.97.194] has quit [Quit: Leaving.] 11:56 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 12:12 < kanzure> "Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069638/ 12:12 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=3c84c2b6 Bryan Bishop: add lin28a overgrowth stuff >> http://diyhpl.us/diyhpluswiki/genetic-modifications/ 12:21 < kanzure> .wik gigantopithecus 12:21 < yoleaux> "" — https://en.wikipedia.org/wiki/Gigantopithecus 12:21 < kanzure> "The primate fossil record suggests that the species Gigantopithecus blacki were the largest known primates that ever lived, standing up to 3 m (9.8 ft) and weighing as much as 540–600 kg (1,190–1,320 lb),[2][5][6][7]" 12:30 < kanzure> https://i.redd.it/erv950swio611.jpg 12:42 < kanzure> what's the difference between horse metallothionein and human metallothionein? 12:42 < kanzure> the hormone one. 12:44 < kanzure> "Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes" https://www.nature.com/articles/300611a0 12:49 < yashgaroth> I don't think there is a metallothionein that functions as a hormone, they use the MT promoter in that paper as it's inducible by metals 12:49 < kanzure> oh. 12:52 < yashgaroth> works well if you're willing to dose mice with zinc, tet induction was discovered after 1982 13:02 < archels> clicking for the pics 13:02 -!- ShaKata [~ShaKata@bzq-79-179-90-156.red.bezeqint.net] has joined ##hplusroadmap 13:03 < archels> pics very disappointing 13:04 < archels> no giant mice pushing up against the inside of their cages 13:06 -!- sektor [~sektor@95.87.234.241] has quit [Ping timeout: 260 seconds] 13:07 -!- sektor [~sektor@95.87.234.241] has joined ##hplusroadmap 13:10 < archels> http://www.iearobotics.com/blog/2012/09/10/enhancing-openscad-with-the-attach-library/ 13:10 < archels> any tips on essential OpenSCAD libraries? 13:11 < archels> http://www.iearobotics.com/blog/2012/09/13/enhancing-openscad-ii-bevel-library/ 13:18 -!- FourFire [~FourFire@234.103.189.109.customer.cdi.no] has joined ##hplusroadmap 13:55 -!- ShaKata [~ShaKata@bzq-79-179-90-156.red.bezeqint.net] has quit [Ping timeout: 244 seconds] 14:05 -!- l_wl [~l_wl@2601:640:8480:1e8e:e07e:872d:d364:37ba] has joined ##hplusroadmap 14:05 -!- l_wl [~l_wl@2601:640:8480:1e8e:e07e:872d:d364:37ba] has quit [Client Quit] 14:23 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: Malvolio] 15:08 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 240 seconds] 15:09 < fenn> .title http://psyarxiv.com/kymhp/ 15:09 < yoleaux> fenn: Sorry, that doesn't appear to be an HTML page. 15:10 < fenn> hrm 15:10 < fenn> .title https://psyarxiv.com/kymhp/ 15:10 < yoleaux> fenn: Sorry, that doesn't appear to be an HTML page. 15:10 < fenn> bastards 15:11 < fenn> paper claiming education increases IQ 1-5 points per year of education 15:31 < jrayhawk> haha what 15:32 < jrayhawk> that must be some extreme observational fuckery 15:55 -!- FourFire [~FourFire@234.103.189.109.customer.cdi.no] has quit [Ping timeout: 256 seconds] 16:09 < streety> I hadn't even thought of libraries for openSCAD. I've nothing to suggest but thanks for the pointer, I've been doing everything with just the basics 16:09 < streety> with "everything" being less than I would like, or at least slower than I would like 16:35 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has joined ##hplusroadmap 17:08 -!- l_wl [~l_wl@2601:640:8480:1e8e:5f9:5e7:ce77:87] has joined ##hplusroadmap 17:18 -!- strages [uid11297@gateway/web/irccloud.com/x-ocnbakfyytowgllq] has quit [Quit: Connection closed for inactivity] 17:51 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has quit [Quit: ...and all my responses they stay the same.] 18:03 -!- mrdata- [~mrdata@unaffiliated/mrdata] has joined ##hplusroadmap 18:18 -!- l_wl [~l_wl@2601:640:8480:1e8e:5f9:5e7:ce77:87] has quit [Remote host closed the connection] 18:22 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has joined ##hplusroadmap 18:38 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 19:05 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:2cd8:f2a2:3866:b488] has quit [Read error: Connection reset by peer] 19:08 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-zyzoynoeyldtbrsz] has quit [Quit: Connection closed for inactivity] 19:17 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:d971:8b3e:d5c2:1872] has joined ##hplusroadmap 19:21 -!- l_wl [~l_wl@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 19:25 < nmz787> yashgaroth: yo 19:25 < yashgaroth> sup 19:26 < nmz787> yashgaroth: is there an enzyme that you can load a primer with, that will then go off and attach to a hybrid of the primer, but only if it's located at an end? 19:28 < nmz787> I was thinking something like maybe what they used in the 'hot start' pcr mixes 19:28 < nmz787> but I can't remember what that is, or how it worked and haven't looked it up 19:28 < yashgaroth> the closest would be uvsx, but you'd have to engineer it somehow to only stick to the end of a strand 19:28 < nmz787> (just remembered to ask you) 19:28 < yashgaroth> hot start is just an antibody that blocks the polymerase from working until the heat denatures it 19:28 -!- l_wl [~l_wl@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 19:29 -!- l_wl [~l_wl@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 19:29 < nmz787> ah 19:30 < nmz787> maybe a loop in the end of the primer? 19:36 < yashgaroth> could help, but generally if someone found a way to reduce incorrect primer annealing it'd be widely used 19:41 -!- fluke` [~user@193.165.237.1] has quit [Read error: Connection reset by peer] 19:42 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 268 seconds] 19:43 -!- fluke` [~user@193.165.237.1] has joined ##hplusroadmap 19:55 < nmz787> well not really incorrect annealing, rather end-only annealing 19:55 < nmz787> i.e. if the sequence contained the complement in the middle, I am thinking of a way to prevent binding there, and only allow if present on the end of the fragment 20:04 < yashgaroth> possibly some bigass molecule attached at the 5' end of the primer, seems crude tho 20:07 < l_wl> how do I get all qualcom libraries for all their chipsets (current) 20:07 < l_wl> 20:00 l_wl: to import into eagle 20:07 < nmz787> get a job there, obviously 20:08 < nmz787> yashgaroth: even with a big-honkin molecule attached at 5', seems like it could still prime most of the primer, and just have that end peeled off a bit (if in the middle of a fragment) 20:11 < yashgaroth> you can try to mitigate it with higher annealing temperatures, there should be a significant difference between fully and partially bound primer if the attachment's big enough...still not 100% but that's biology 20:14 -!- mrdata- [~mrdata@unaffiliated/mrdata] has quit [Read error: Connection reset by peer] 20:14 < nmz787> hmm 20:15 < nmz787> maybe good enough 22:10 -!- ebowden [~ebowden@128.250.0.195] has quit [Ping timeout: 265 seconds] 22:13 -!- ebowden [~ebowden@128.250.0.195] has joined ##hplusroadmap 22:15 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:d971:8b3e:d5c2:1872] has quit [Quit: Leaving] 22:35 -!- aeiousom1thing [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 22:37 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 240 seconds] 23:32 -!- l_wl [~l_wl@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] --- Log closed Thu Jul 12 00:00:14 2018