--- Log opened Sun Jul 22 00:00:17 2018 00:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 00:05 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 00:07 -!- jtimon [~quassel@213.28.134.37.dynamic.jazztel.es] has quit [Ping timeout: 260 seconds] 00:14 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 00:14 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 00:21 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-ibgcawouzxekzhez] has joined ##hplusroadmap 00:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 00:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 00:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 00:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 00:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 00:55 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 01:08 -!- strages [uid11297@gateway/web/irccloud.com/x-suwefdmsrahimatw] has joined ##hplusroadmap 01:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 01:25 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 01:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 01:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 02:08 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Remote host closed the connection] 02:08 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 02:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 02:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 02:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 02:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 03:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 03:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 03:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 03:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 03:44 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 03:44 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 03:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 03:55 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 03:58 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-ibgcawouzxekzhez] has quit [Quit: Connection closed for inactivity] 04:14 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 04:15 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 04:32 -!- rockboy [ac382a24@gateway/web/freenode/ip.172.56.42.36] has joined ##hplusroadmap 04:37 -!- rockboy [ac382a24@gateway/web/freenode/ip.172.56.42.36] has quit [Quit: Page closed] 04:55 -!- fluke` [~user@193.165.237.1] has quit [Read error: Connection reset by peer] 04:56 -!- fluke` [~user@193.165.237.1] has joined ##hplusroadmap 05:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 05:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 05:08 -!- sektor [~sektor@95.87.234.241] has quit [Remote host closed the connection] 05:18 < kanzure> maaku: who cares tho? mitochondrial damage is a real thing that occurs outside the lab. 05:21 -!- jtimon [~quassel@213.28.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 05:22 < kanzure> "But she warned that there could be unintended consequences if the law were changed to allow gene editing of human embryos. While the technology could potentially reduce the number of people affected by certain genetic disorders, it could leave those with the diseases feeling more marginalised and with less medical support." 05:22 < kanzure> O_O 05:28 -!- sektor [~sektor@95.87.234.241] has joined ##hplusroadmap 05:28 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 05:31 -!- Kacia [~kacia@95.87.234.241] has quit [Read error: Connection reset by peer] 05:35 < kanzure> Aach J, Lunshof J, Iyer E, Church GM (2017) Addressing the ethical issues raised by synthetic human entities with embryo-like features. Elife 05:35 -!- farmerwampum [~farmerwam@88.202.178.98] has quit [Read error: Connection reset by peer] 05:37 < kanzure> 2E. Busskamp et al. (2014) Rapid neurogenesis through transcriptional activation in stem cells. MSB 05:37 < kanzure> 2H. Ng, Khoshakhlagh et al. (2018) Programming cell fates [in prep] 05:39 < kanzure> various church things http://arep.med.harvard.edu/gmc/ppt/18Jul20_Hack_Church.pdf 05:42 < kanzure> .title https://pgp.med.harvard.edu/events/pgp-hackathon-1-0 05:42 < yoleaux> PGP Hackathon 1.0 – The Harvard Personal Genome Project (PGP) 05:43 < kanzure> solvespace in a browser https://files.whitequark.org/SolveSpace/solvespace.html 05:44 < kanzure> "Molecular Imprinting: The missing piece in the puzzle of abiogenesis?" https://arxiv.org/abs/1807.07065 05:44 < kanzure> ^drexler stuff 05:52 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 05:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 05:54 -!- Kacia [~kacia@95.87.234.241] has quit [Read error: Connection reset by peer] 05:55 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 05:59 -!- jabellz [~jake@host31-51-179-162.range31-51.btcentralplus.com] has joined ##hplusroadmap 06:03 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 06:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 06:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 06:11 < ebowden_> a better title would be "wrinkled skin and hair loss observed when mitochondrial function disrupted; skin and hair returns to normal following resumption of mitochondrial function" 06:11 < ebowden_> What paper is maaku talking about. 06:11 < ebowden_> What paper is maaku talking about? 06:18 < kanzure> https://www.nature.com/articles/s41419-018-0765-9 06:21 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 06:46 < kanzure> every year, the IQ required to destroy the galaxy decreases by one IQ point. 06:51 < kanzure> .title https://news.ycombinator.com/item?id=17586547 06:51 < yoleaux> Intel ME remote code execution vulnerability in all current processors | Hacker News 06:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 06:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 06:54 < archels> how does AMD stack up against the recent slew of Intel vulnerabilities? 07:03 -!- jake_ [~jake@host86-182-91-183.range86-182.btcentralplus.com] has joined ##hplusroadmap 07:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 07:05 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 07:06 -!- jabellz [~jake@host31-51-179-162.range31-51.btcentralplus.com] has quit [Ping timeout: 276 seconds] 07:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 07:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 07:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 07:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 07:44 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 07:44 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 07:46 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 268 seconds] 07:47 < kanzure> .tw https://twitter.com/eboyden3/status/1020317871560364033 07:47 < yoleaux> Two-color activation of two populations of neurons, expressing (blue light-driven) Chronos and (red light-driven) Chrimson, enables in vivo induction of synaptic plasticity that alters alcohol consumption. https://www.nature.com/articles/s41593-018-0081-9 (@eboyden3) 07:48 < kanzure> "Automated in vivo patch clamp evaluation of extracellular multielectrode array spike recording capability" https://www.physiology.org/doi/abs/10.1152/jn.00650.2017?journalCode=jn https://twitter.com/eboyden3/status/1018218817007357955 07:49 < kanzure> "A suite of transgenic driver and reporter mouse lines with enhanced brain-cell-type targeting and functionality" https://www.cell.com/cell/fulltext/S0092-8674(18)30803-1 https://twitter.com/eboyden3/status/1017481845313810432 07:50 < kanzure> "Local protein synthesis in axon terminals and dendritic spines differentiates plasticity contexts" https://www.biorxiv.org/content/early/2018/07/05/363184 08:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 08:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 08:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 08:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 09:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 09:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 09:05 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 09:23 -!- fluke` [~user@193.165.237.1] has quit [Read error: Connection reset by peer] 09:24 -!- fluke` [~user@193.165.237.1] has joined ##hplusroadmap 09:45 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:9806:86bb:6140:6e4] has joined ##hplusroadmap 10:06 -!- fluke` [~user@193.165.237.1] has quit [Read error: Connection reset by peer] 10:07 < Jenda> archels: AMD does not have Meltdown, but Spectre have all powerful processors 10:08 -!- fluke` [~user@193.165.237.1] has joined ##hplusroadmap 10:09 < Jenda> archels: And regarding ME - AMD has PSP, which is kind of similar. See https://www.coreboot.org/Binary_situation#recent_AMD 10:16 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 10:18 -!- fluke` [~user@193.165.237.1] has quit [Read error: Connection reset by peer] 10:19 -!- fluke` [~user@193.165.237.1] has joined ##hplusroadmap 10:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 10:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 10:25 -!- nullniverse [~nullniver@unaffiliated/nullniverse] has joined ##hplusroadmap 10:30 -!- fluke` [~user@193.165.237.1] has quit [Ping timeout: 276 seconds] 10:32 -!- fluke` [~user@193.165.237.1] has joined ##hplusroadmap 10:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 10:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 10:40 -!- sivoais [~zaki@unaffiliated/sivoais] has quit [Ping timeout: 248 seconds] 10:44 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 10:44 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 10:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 10:54 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 11:11 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 11:14 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 11:15 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 11:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 11:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 12:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 12:04 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 12:24 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 12:25 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 12:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 12:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 12:44 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 12:44 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 13:09 -!- jake_ [~jake@host86-182-91-183.range86-182.btcentralplus.com] has quit [Quit: Leaving] 13:32 < kanzure> alright we need to kill redlegion 13:34 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Max SendQ exceeded] 13:35 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 13:35 -!- mode/##hplusroadmap [+o kanzure] by ChanServ 13:35 -!- mode/##hplusroadmap [+b redlegion!*@*] by kanzure 13:35 -!- redlegion was kicked from ##hplusroadmap by kanzure [redlegion] 13:35 -!- mode/##hplusroadmap [-o kanzure] by kanzure 13:54 < fenn> .title http://youtu.be/jAhjPd4uNFY 13:54 < yoleaux> Genetic Engineering Will Change Everything Forever – CRISPR - YouTube 13:54 < fenn> this is kurzgesagt, which has lots of entertaining science cartoons 14:10 -!- Burnin8 is now known as Burninate 14:16 -!- Kacia [~kacia@95.87.234.241] has quit [Ping timeout: 276 seconds] 14:17 -!- Kacia [~kacia@95.87.234.241] has joined ##hplusroadmap 14:52 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: Malvolio] 15:01 -!- red-001 [red@gateway/shell/elitebnc/x-beumrsfyqynmybit] has quit [Ping timeout: 240 seconds] 15:06 -!- red-001 [red@gateway/shell/elitebnc/x-byxcwjckiqpmtbel] has joined ##hplusroadmap 16:01 < kanzure> hmph 16:01 < kanzure> this is cheating, red 16:09 -!- nullniverse [~nullniver@unaffiliated/nullniverse] has quit [Quit: Undertaking stack overflow prevention] 18:41 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 276 seconds] 18:42 -!- mgxm [~mgxm@unaffiliated/mgxm] has quit [Read error: Connection reset by peer] 18:42 -!- mgxm_ [~mgxm@unaffiliated/mgxm] has joined ##hplusroadmap 18:42 -!- mgxm_ is now known as mgxm 19:06 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 19:55 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has quit [Quit: ...and all my responses they stay the same.] 20:50 -!- ebowden_ [~ebowden@128.250.0.202] has quit [Read error: Connection reset by peer] 20:50 -!- ebowden [~ebowden@128.250.0.202] has joined ##hplusroadmap 21:09 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 256 seconds] 21:23 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:9806:86bb:6140:6e4] has quit [Ping timeout: 260 seconds] --- Log closed Mon Jul 23 00:00:18 2018