--- Log opened Mon Dec 24 00:00:00 2018
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08:05 < kanzure> "A computational framework for DNA sequencing-based microscopy" https://www.biorxiv.org/content/early/2018/11/21/476200.1
08:05 < kanzure> "We describe a method whereby micro-scale spatial information such as the relative positions of biomolecules on a surface can be transferred to a sequence-based format and reconstructed into images without the use of conventional optics. The principle is based on the pairwise association of uniquely tagged and spatially adjacenct polonies. The network of polonies connected by shared borders ...
08:06 < kanzure> ...forms a graph whose topology can be reconstructed from a set of edges derived from pairs of barcodes associated with each other during a polony crosslinking phase, the sequences of which could be determined by isolation of the DNA and next-gen sequencing. We developed a mathematical and computational framework for this principle called Polony Adjacency Reconstruction for Spatial Inference and ...
08:06 < kanzure> ...Topology and show that Euclidean spatial data may be partially stored and transmitted in the form of untethered graph topology. This effect may be exploited to form images by transferring molecular information from a surface of interest, which we demonstrated in silico by reconstructing images formed from stochastic transfer of hypothetical red, green, and blue molecular markers. The theory ...
08:06 < kanzure> ...developed here could serve as a guide for a highly automated, multiplexable, and potentially super resolution imaging method based on molecular information encoding and transmission."
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09:52 < kanzure> "3d character animation from a single photo" https://grail.cs.washington.edu/projects/wakeup/
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11:06 < fenn> literally nightmare fuel
11:06 < fenn> this research paper is probably the beginning of a horror movie
11:21 < nmz787> i've been waiting for this to become a reality for a long time
11:22 < Urchin> fenn: what paper?
11:23 < jrayhawk> http://gnusha.org/logs
11:26 < Urchin> photo wakeup or?
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--- Log closed Tue Dec 25 00:00:01 2018