--- Log opened Sun Feb 03 00:00:39 2019 00:09 -!- hard [~hard@105.235.131.248] has quit [Ping timeout: 240 seconds] 01:24 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 01:28 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 244 seconds] 02:15 -!- spaceangel [~spaceange@ip-86-49-16-65.net.upcbroadband.cz] has joined ##hplusroadmap 02:19 -!- jtimon [~quassel@92.28.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 02:41 -!- CryptoDavid [uid14990@gateway/web/irccloud.com/x-vqxkluwlhqapexpw] has joined ##hplusroadmap 03:48 -!- uniera [uniera@gateway/vpn/privateinternetaccess/uniera] has joined ##hplusroadmap 04:50 -!- CryptoDavid [uid14990@gateway/web/irccloud.com/x-vqxkluwlhqapexpw] has quit [Quit: Connection closed for inactivity] 04:55 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 05:17 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 246 seconds] 06:27 -!- uniera [uniera@gateway/vpn/privateinternetaccess/uniera] has quit [Quit: Leaving...] 07:36 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 08:08 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 08:16 < kanzure> nmz787: wonder if mRNA delivery could make a spicy tomato without germline edits 08:16 -!- Mediphira [~Mediphira@136.0.0.107] has joined ##hplusroadmap 08:16 -!- Mediphira [~Mediphira@136.0.0.107] has left ##hplusroadmap [] 08:57 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:50aa:1d33:44a6:4246] has joined ##hplusroadmap 09:00 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 268 seconds] 09:06 -!- jtimon [~quassel@92.28.134.37.dynamic.jazztel.es] has quit [Ping timeout: 268 seconds] 09:17 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 245 seconds] 09:53 -!- sachy [~sachy@91.146.121.5] has joined ##hplusroadmap 10:00 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 10:51 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 246 seconds] 11:05 -!- CryptoDavid [uid14990@gateway/web/irccloud.com/x-xvuryaugqzgtcvrr] has joined ##hplusroadmap 11:16 < nmz787> kanzure: hmm, that seems plausible, though I wonder if it would be a lasting cascade effect, or just stop local to the cells that got the mRNA dose 11:39 -!- jtimon [~quassel@92.28.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 11:39 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 11:56 -!- sachy [~sachy@91.146.121.5] has quit [Read error: Connection reset by peer] 11:57 -!- sachy [~sachy@91.146.121.5] has joined ##hplusroadmap 13:14 -!- CryptoDavid [uid14990@gateway/web/irccloud.com/x-xvuryaugqzgtcvrr] has quit [Quit: Connection closed for inactivity] 13:52 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 14:00 -!- Jay_Dugger [~jwdugger@47.185.249.138] has joined ##hplusroadmap 14:00 -!- Jay_Dugger [~jwdugger@47.185.249.138] has quit [Client Quit] 14:14 < justanotheruser> how can you do a dna test without the company selling your dna to the fbi? 14:15 < justanotheruser> sequence it diy then plug it into some FOSS analysis tool? 14:23 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 15:24 < nmz787> justanotheruser: that'd work 15:25 < justanotheruser> what is the best tool/database for this? 15:27 < nmz787> been half a decade since I really checked, but it depends on what you're after 15:28 < nmz787> BLAST is one tool 15:28 < nmz787> that will just show the diff between old fogeys that were the first guys to be sequenced mainly 15:28 < nmz787> (or any other reference you might get your hands on) 15:37 < fenn> justanotheruser: https://www.snpedia.com/ 15:37 < fenn> i thought promethease was open source but now it seems to be a paid for service 15:39 < justanotheruser> tyvm, checking BLAST and snpedia 15:40 < fenn> BLAST is for finding sequence similarity and probably not what you want 15:40 < fenn> it'll be like, "your gene is similar to that found in humans, chimpanzees, yeast" etc 15:41 < justanotheruser> I see. Still worth checking it out once I already have the sequence 15:42 < fenn> so you can find exactly where you were bitten by the radioactive spider 15:46 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 246 seconds] 16:19 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 250 seconds] 16:32 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 16:36 < nmz787> SNPedia search will really just compare your genome SNPs versus known SNPs 16:36 < nmz787> so it's sort of BLAST against specific chunks 16:37 < nmz787> but also show what's known about those chunks when they differ at that location 16:38 < nmz787> but like, if you were doing a paternity test or something, you could use BLAST to check overlap of you and the supposed father 16:38 < nmz787> even though in practice RFLP is used, just because it is cheaper and faster than whole genome seq 16:38 < nmz787> .wik rflp 16:38 < yoleaux> "In molecular biology, restriction fragment length polymorphism (RFLP) is a technique that exploits variations in homologous DNA sequences. It refers to a difference between samples of homologous DNA molecules from differing locations of restriction enzyme sites, and to a related laboratory technique by which these segments can be illustrated." — https://en.wikipedia.org/wiki/Rflp 16:39 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 17:25 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 268 seconds] 17:44 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 18:38 -!- spaceangel [~spaceange@ip-86-49-16-65.net.upcbroadband.cz] has quit [Remote host closed the connection] 20:36 -!- Proteus [~Proteus@unaffiliated/proteus] has quit [Quit: Leaving.] 21:09 -!- jtimon [~quassel@92.28.134.37.dynamic.jazztel.es] has quit [Ping timeout: 268 seconds] 21:49 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:50aa:1d33:44a6:4246] has quit [Quit: Leaving] --- Log closed Mon Feb 04 00:00:39 2019