--- Log opened Tue Mar 19 00:00:06 2019 --- Day changed Tue Mar 19 2019 00:00 -!- juul [~juul@juul.io] has joined ##hplusroadmap 00:06 -!- anonnumberanon [~anonnumbe@unaffiliated/anonnumberanon] has joined ##hplusroadmap 00:15 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 00:18 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 246 seconds] 02:09 -!- darsie [~kvirc@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap 03:05 -!- pompolic [~A@unaffiliated/pompolic] has quit [Ping timeout: 245 seconds] 03:36 -!- midnightmagic [~midnightm@unaffiliated/midnightmagic] has quit [Ping timeout: 264 seconds] 04:44 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 04:47 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 268 seconds] 04:56 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 04:56 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 05:14 < nsh> nmz787_, nice! 05:57 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has joined ##hplusroadmap 06:21 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has quit [Ping timeout: 272 seconds] 06:33 < kanzure> someone applied tomography to baking? alright. 06:56 < kanzure> glims seeks validation for biohackers https://www.facebook.com/gabriel.licina/posts/10157054049929603 06:56 < kanzure> https://medium.com/@notgrubles/completely-offline-bitcoin-transactions-4e58324637bd 07:00 < nsh> .head https://medium.com/@notgrubles/completely-offline-bitcoin-transactions-4e58324637bd Last-Modified 07:00 < yoleaux> Sorry, there was no Last-Modified header in the response. 07:01 < nsh> i hate things that don't have a visible date in the top line or so 07:01 < nsh> ah Feb 7, of some year 07:02 < kanzure> air gap + commodity hardware seems to be the way to go; i am having trouble justifying "secure elements" on connected devices. 07:02 < kanzure> or even "secure elements" on airgapped devices 07:03 < kanzure> regretfully the material i covered when teaching the smartcustody.com workshop did not include multisig setups 07:09 < kanzure> .wik genethics 07:09 < yoleaux> "The Institute for Science, Ethics and Innovation (iSEI) is a research institute founded at the University of Manchester in 2007 with a mission to examine the role and moral responsibilities of science, technology and innovation in the contemporary world." — https://en.wikipedia.org/wiki/Institute_for_Science,_Ethics_and_Innovation 07:09 < kanzure> hmph 07:09 < kanzure> more james hughes i guess. 07:20 < kanzure> i thought of a way to make human embryo modification available to everyone "for free" (and it's not infecting the human population with viral gene therapy for once) but it has a pretty big downside. 07:32 -!- pompolic [~A@unaffiliated/pompolic] has joined ##hplusroadmap 07:43 < nsh> decoding linear B is available to everyone 07:43 < nsh> i doubt anyone is going to do it 07:44 < nsh> anytime soon :) 07:45 < nsh> (which is to say it's a conceit to think that universal franchise even when made more likely is not going to actualise into a very limited franchise due to the fact that not everybody can or wants or (indeed especially) should act on that franchise) 07:45 < nsh> (point ventured without explicit implicit criticism) 07:45 < nsh> +or 08:15 -!- strages [uid11297@gateway/web/irccloud.com/x-mkmemmttghoqtzyc] has joined ##hplusroadmap 08:24 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has joined ##hplusroadmap 08:43 -!- yashgaroth [~yashgarot@2606:6000:ca81:3100:9018:9211:5c11:660b] has joined ##hplusroadmap 09:01 -!- midnightmagic [~midnightm@unaffiliated/midnightmagic] has joined ##hplusroadmap 09:10 < kanzure> http://nautil.us/issue/18/genius/super_intelligent-humans-are-coming 09:11 < von-strauss> hi 09:19 < kanzure> https://cdn1.sph.harvard.edu/wp-content/uploads/sites/94/2016/01/STAT-Harvard-Poll-Jan-2016-Genetic-Technology.pdf 09:21 < nsh> sufficiently super-intelligent beings once they exist exist at all times :) 09:21 < nsh> so coming is a function of the sub-intelligent human's understanding of time 09:48 < von-strauss> hi nsh 09:48 < nsh> h2u 09:54 < von-strauss> i have a phone interview later today 09:54 < von-strauss> any tips 09:56 < kanzure> interview for what? 10:00 -!- delinquentme [~delinquen@c-73-15-72-140.hsd1.ca.comcast.net] has joined ##hplusroadmap 10:02 < von-strauss> kanzure, java dev 10:03 < von-strauss> i like designing finite state machines and doing automated reasoning in ML 10:03 < von-strauss> but thats not what they want 10:18 < kanzure> talk about gradle and maven a lot and you'll be fine 10:20 < von-strauss> i wouldnt be prepared to discuss those 10:20 < von-strauss> as ive never used them 10:20 < von-strauss> in fact, i would never choose java for any personal project 10:21 < von-strauss> either homoiconicity or a good type system obviate the need for ridiculous "oop sound design patterns" 10:22 < von-strauss> oop is a political, corporate, authoritarian idea 10:36 -!- NikopolSohru [~Nikopol_@185.217.171.8] has joined ##hplusroadmap 10:57 -!- NikopolSohru [~Nikopol_@185.217.171.8] has quit [Changing host] 10:57 -!- NikopolSohru [~Nikopol_@unaffiliated/nikopolsohru] has joined ##hplusroadmap 11:05 -!- NikopolSohru [~Nikopol_@unaffiliated/nikopolsohru] has quit [Quit: Leaving] 11:05 -!- NikopolSohru [~Nikopol_@185.217.171.8] has joined ##hplusroadmap 11:05 -!- NikopolSohru [~Nikopol_@185.217.171.8] has quit [Changing host] 11:05 -!- NikopolSohru [~Nikopol_@unaffiliated/nikopolsohru] has joined ##hplusroadmap 11:51 -!- yashgaroth [~yashgarot@2606:6000:ca81:3100:9018:9211:5c11:660b] has quit [Read error: Connection reset by peer] 11:52 -!- yashgaroth [~yashgarot@cpe-76-176-31-235.san.res.rr.com] has joined ##hplusroadmap 12:01 -!- yashgaroth [~yashgarot@cpe-76-176-31-235.san.res.rr.com] has quit [Read error: Connection reset by peer] 12:04 -!- yashgaroth [~yashgarot@cpe-76-176-31-235.san.res.rr.com] has joined ##hplusroadmap 12:22 < kanzure> https://www.statnews.com/2019/03/19/who-advisers-call-for-registry-of-human-genome-editing/ 12:23 < kanzure> "A World Health Organization advisory committee on editing human DNA will ask the United Nations agency to establish a global registry of all such research, recommend that editors of scientific journals not publish any unregistered studies, and ask science funders to require that their grantees register their studies, committee co-chair Dr. Margaret Hamburg told reporters on Tuesday. The ... 12:23 < kanzure> ...registry would include studies that edit the DNA of eggs, sperm, and early embryos, called germline editing, and those that edit adult cells for the purpose of curing disease, which is much less controversial and is the focus of all genome-editing companies." 12:23 < kanzure> "Even before such mechanisms are in place, Hamburg said at the close of the group’s first meeting, “the committee agrees that it is irresponsible for anyone to proceed with human germline genome editing.” The committee did not, however, explicitly recommend a moratorium on germline editing for reproduction." 13:06 < von-strauss> i got the job kanzure 13:29 < nsh> well done! <3 13:48 < von-strauss> i thought it was a second round but it was just an offer 14:02 -!- delinquentme [~delinquen@c-73-15-72-140.hsd1.ca.comcast.net] has quit [Quit: Leaving] 14:10 < nmz787_> kanzure: interesting re: free mods for all... would like to hear more deets 14:20 < von-strauss> hi nmz787_ 15:05 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has quit [Remote host closed the connection] 15:05 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has joined ##hplusroadmap 15:10 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has quit [Ping timeout: 250 seconds] 15:47 -!- yashgaroth [~yashgarot@cpe-76-176-31-235.san.res.rr.com] has quit [Read error: Connection reset by peer] 15:54 -!- yashgaroth [~yashgarot@cpe-76-176-31-235.san.res.rr.com] has joined ##hplusroadmap 16:10 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 250 seconds] 16:17 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has joined ##hplusroadmap 16:23 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 16:26 -!- spaceangel [~spaceange@ip-86-49-16-65.net.upcbroadband.cz] has quit [Remote host closed the connection] 16:31 -!- LeoTal [~Adium@201.170.86.79.rev.sfr.net] has quit [Ping timeout: 246 seconds] 16:54 -!- NikopolSohru [~Nikopol_@unaffiliated/nikopolsohru] has quit [Quit: Leaving] 18:01 < fenn> just wear this badge on your arm at all times. what's the problem, it's just a badge! 18:15 < kanzure> .tw https://twitter.com/RLCscienceboss/status/1104991257514950656 18:15 < yoleaux> Yang Hui, a Chinese #CRISPR scientist who led the base editor off-target mutation published in Science a week and a half ago, is "...said his group was racing to develop a new gene editor that would be safe for everyone." https://www.scmp.com/news/china/science/article/2189395/chinas-race-test-mutation-free-gene-editing-technology-cancer (@RLCscienceboss) 18:38 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has quit [Remote host closed the connection] 18:38 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has joined ##hplusroadmap 18:49 -!- von-strauss [~von-strau@unaffiliated/pineaucharentais] has quit [Ping timeout: 250 seconds] 18:51 -!- strages [uid11297@gateway/web/irccloud.com/x-mkmemmttghoqtzyc] has quit [Quit: Connection closed for inactivity] 19:15 -!- Gurkenglas [~Gurkengla@unaffiliated/gurkenglas] has quit [Ping timeout: 250 seconds] 19:47 -!- l_wl [~l_wl@pool-108-45-141-95.washdc.fios.verizon.net] has quit [Remote host closed the connection] 19:48 -!- l_wl [~l_wl@pool-108-45-141-95.washdc.fios.verizon.net] has joined ##hplusroadmap 20:16 -!- darsie [~kvirc@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 245 seconds] 21:29 -!- LeoTal [~Adium@201.170.86.79.rev.sfr.net] has joined ##hplusroadmap 22:41 -!- yashgaroth [~yashgarot@cpe-76-176-31-235.san.res.rr.com] has quit [Quit: Leaving] 23:19 < mrdata_> fenn, a badge like this one? http://cdn.shopify.com/s/files/1/1371/9221/products/Resize_Badges_0018_Mutant_grande.jpg?v=1523344116 23:47 < mrdata_> or maybe https://pallbearerpress.com/wp-content/uploads/2016/01/MUTANT.jpg --- Log closed Wed Mar 20 00:00:20 2019