--- Log opened Fri Nov 29 00:00:22 2019
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08:56 < kanzure> barseq > mapseq https://www.sciencedaily.com/releases/2019/10/191017141038.htm
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09:22 < kanzure> .scihub "DNA sequencing in high-throughput neuroanatomy"
09:22 < kanzure> "I see that Zador's genius Klebschull (now at Stanford, I'm trying to contact) has a full roadmap for Synaptome capture: "synaptic barcode localization with in situ barcode sequencing (Chen et al., 2018), and expansion microscopy (Chozinski et al., 2016; Chang et al., 2017; Chen et al., 2015; Wassie et al., 2019) (ExM) provides an alternative avenue for high-throughput synaptic connectomics. ...
09:22 < kanzure> ...Here, pre- and post-synaptically localized barcodes would be detected and read out by in situ sequencing in expanded tissue. The high effective resolution of ExM in combination with synaptic marker staining, or the restriction of in situ sequencing to synapses, would then allow to map synaptic connectivity by simply associating proximal barcodes with each other (compare also refs (Marblestone ...
09:22 < kanzure> ...et al., 2014; Yoon et al., 2017; Underwood, 2016; Mishchenko, 2010)). "
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15:41 < kanzure> "Feasibility of 3d reconstruction of neural morphology using extension microscopy and barcode-guided agglomeration" https://diyhpl.us/~bryan/papers2/neuro/Feasibility%20of%203d%20reconstruction%20of%20neural%20morphology%20using%20extension%20microscopy%20and%20barcode-guided%20agglomeration%20-%20Marblestone%20-%20Boyden%20-%202017.pdf (2017)
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16:42 < kanzure> https://www.capitalismmagazine.com/2005/08/the-animal-rights-movements-cruelty-to-humans/
16:42 < kanzure> https://www.capitalismmagazine.com/2004/02/to-ban-cloning-would-be-a-moral-abomination/
16:42 < kanzure> https://www.capitalismmagazine.com/2003/11/cloning-is-a-pro-life-technology/
16:42 < kanzure> https://www.capitalismmagazine.com/2015/12/ethics-of-human-genetic-engineering-and-cloning/
16:42 < kanzure> https://www.capitalismmagazine.com/2003/01/human-cloning-raelians-vs-reality/
16:42 < kanzure> https://www.capitalismmagazine.com/2002/04/cloning-in-a-free-society/
16:42 < kanzure> https://www.capitalismmagazine.com/2019/07/the-federal-death-agency-fda/
16:46 < kanzure> "The immorality of the FDA lies in its forbidding individual judgment. The FDA exists solely to arrest anyone who acts without permission. The FDA does not exist to provide expert opinion on medical substances and practices: private, non-governmental voluntary certification does that. What the FDA adds is the power to arrest and imprison those who dare to disagree with its medical opinions."
16:47 < kanzure> "And that takes us to the deepest point. The necessary result of throttling private judgments is: mass death. I don't mean just the deaths of those millions of diseased individuals who cannot get the life-saving drugs. Much worse is the fact that outlawing private judgment means a drastically shorter life-span for every one of us. Let me try to concretize the extent of this tragedy. If ...
16:47 < kanzure> ...America had continued through the 20th century the nearly laissez-faire system of the 19th, it's a good bet that Ayn Rand would be alive today at age 113, and would still be in good health. It is quite likely that, had we continued with almost-full capitalism, then the Millennials would have a lifespan of 200 years, or longer. The reason that sounds like fantasy is that the statism that has ...
16:47 < kanzure> ...hamstrung America for so long has lowered our expectations of progress."
16:48 < kanzure> "So why has U.S. life expectancy gone only to 78.7 in the 97 years since it hit 60? Why isn't life expectancy now over 100? In fact, since knowledge builds on knowledge and wealth builds on wealth, the rate of increase should have been accelerating! You might think that there's some inherent limit on the span of a human life. I don't think there is, and neither do lots of people better ...
16:48 < kanzure> ...informed than I. Especially not when there is the ability to re-program our DNA. The path to genetic cures and radical life extension begins with the abolition of that Servant of Death: the FDA."
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18:30 < kanzure> .wik interspecific pregnancy
18:30 < EmmyNoether> "Interspecific pregnancy (literally pregnancy between species, also called interspecies pregnancy or xenopregnancy) is the pregnancy involving an embryo or fetus belonging to another species than the carrier." - https://en.wikipedia.org/wiki/Interspecific_pregnancy
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21:24 < lsneff> Surprisingly bad essay published in aeon: https://aeon.co/essays/your-brain-does-not-process-information-and-it-is-not-a-computer
21:25 < lsneff> The author believes that the brain does not process information
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21:42 < jrayhawk> you see, the brain is just metaphor all the way down
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23:08 < fenn> the brain is a social construct
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--- Log closed Sat Nov 30 00:00:23 2019