--- Log opened Wed Mar 04 00:00:12 2020
00:04 < offseccat> I dont want any subsitutes actually, But sure thats one way.
00:12 < jrayhawk> Neither are intrinsically harmful, which is more than can be said for volatile particulate solids being deposited in the lungs.
00:14 < jrayhawk> Cholinergics, adrenergics, and MAOIs are common long-term treatments for a variety of psychiatric problems for which there aren't clear alternatives.
00:16 < jrayhawk> it might be prudent to be open to the possibility that you use these things habitually for a reason.
00:21 < jrayhawk> Which will also figure into any "biohacks" you'd want to think about.
00:22 < jrayhawk> such as e.g. phosphatidylcholine for dopamine upregulation https://en.wikipedia.org/wiki/Citicoline
00:28 < fltrz> offseccat, are you trying to quite smoking for coronavirus
00:29 < fltrz> is there a dependency DAG for human anabolism of amino acids
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00:43 < offseccat> fltrz actually no, not about coronavirus rather im sick of smoking, yet i cant seem to stop
00:47 < fltrz> offseccat, I have been repeatedly starting and stopping on purpose for a few weeks
00:47 < fltrz> offseccat, I also remembered it as very hard, but really its just 48 hours or so
00:47 < fltrz> the physical part
00:48 < fltrz> the reason I'm restarting intentionally is to associate the starting with smoking with having to kick off again
00:49 < fltrz> with alcohol I have zero problems with occasionally getting drunk when I want to, because of the hangover. the hangover spontaneously discourages me from drinking for a week or 2
00:49 < fltrz> smoking doesn't give me a hangover
00:50 < fltrz> but kicking off (the physical addiction of the first 48 hrs) feels like a hangover
00:50 < fltrz> I want to be able to occasionally smoke and then not smoke for a few weeks or months
00:50 < fltrz> but I have to psychologically associate starting to smoke again with having to kick off
00:51 < fltrz> all the smokers that get readdicted after a few weeks, months, years ... typically don't try to quit again for another year or so
00:52 < fltrz> so they are unable to associate smoking with the frustration of physically kicking off for 2 days
00:53 < fltrz> offseccat, it also rely improves your self-confidence about being able to quit smoking when you know you have repeatedly gone from regression to not smoking a cigarette for a day or three
00:54 < fltrz> now I can not at all identify with how hard I previously felt quiting smoking was during the first 24 hours
00:54 < fltrz> I actually believe it will be possible to become a casual smoker
00:54 < offseccat> Hmm, You got a solid point actually.
00:55 < fltrz> where I dont smoke for a month or two, and then smoke a lot, actually enjoy it, and then have my "smoking-hangover" for 2 days... just like the alcoholic hangover is the price you pay for the temporary joy...
00:57 < fltrz> but don't tell this to people who quite smoking and never touched one again, as they tend to get pissed off with the insinuation they remain at risk if they ever touch another cigarette
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02:32 < adlai> maaku: i spent a short while studying lojban, although my motivation dropped sharply after a few weeks.
02:33 < adlai> fltrz: you seem to be assigning agency to viral ensembles; perhaps you'd like to refactor statistical mechanics towards configuration space as described by heterogenously weighted graphs?
02:52 < fltrz> adlai, got to leave for work now, ... I am not sure I understand your proposal?
02:52 < fltrz> or rather I am sure I am misunderstanding
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05:47 < archels_> https://nextstrain.org/narratives/ncov/sit-rep/2020-01-30
05:47 < archels_> really beautifully done
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09:44 < kanzure> .title https://www.nytimes.com/2020/03/02/opinion/contributors/pharma-vaccines.html
09:44 < saxo> pharma-vaccines
09:45 < kanzure> "... That was undoubtedly the case the last time Congress approved a national vaccination program in 1976 for swine flu, when 45 million Americans were inoculated. For several months, four drug firms — Merck’s Sharp & Dohme, Merrell, Wyeth, and Parke-Davis — refused to sell to the government the 100 million doses they had manufactured until they got full liability indemnity and a ...
09:45 < kanzure> ...guaranteed profit."
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09:45 < kanzure> "While the four pharmaceutical companies got millions, the Department of Justice ultimately had to assign 10 attorneys to defend full time more than 4,000 legal claims for damages from Guillain-Barré, a rare but serious disorder in which the immune system assaults healthy nerve cells. Taxpayer-funded settlements and judgments eventually topped $100 million."
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09:50 < fenn> i want a guaranteed profit too
09:50 < fenn> can i sue the federal govt for that
09:50 < kanzure> this is america, you can sue for anything
09:51 < fenn> it's probably worth writing off $100m to make sure a vaccination program happens
09:51 < fenn> for a big one like swine flu especially
09:52 < fenn> not that you'd know ahead of time what that number would be
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10:44 < kanzure> hmph
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12:34 < kanzure> "Privacy-friendly Monero transaction signing on a hardware wallet, extended version" https://eprint.iacr.org/2020/281
13:15 < maaku> adlai: the 5-sentence summary of lojban sounds great. the implementation is a big pile of "wtf?"
13:15 < maaku> adlai: if you're truly interested, my project is really to create what loglan/lojban should have been
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13:55 < fenn> 12 years ago me would have been interested
13:55 < fenn> maybe once we get the borg cult up and running
14:10 < juri_> fenn: we are borg.
14:10 < juri_> just prototypes...
14:19 < maaku> I think there is practical relevance. Event semantics makes a good intermediate knowledgebase language for artificial intelligence and bayesian models generally
14:20 < maaku> And there's an application to the interface between smart contract programming and legal contracts
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15:19 < lsneff> This sounds really interesting mark
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19:14 < maaku> lsneff: I'll prioritize writing up a proposal .. in my copious spare time
19:14 < maaku> no snark meant, I will try to write something up. just might take a while
19:17 < lsneff> Ah yes, I relate. So many projects, so much uncertainty, so little time.
19:31 < kanzure> this is literally the only person to ever beat me at typing https://www.youtube.com/watch?v=zNhEfSTVm_M
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19:59 < fenn> add him to the cloning queue
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22:31 < heath> .title https://www.youtube.com/playlist?list=PLTW2MN17j-L12h8Jq5fGGt8VV1ISZT-De
22:32 < saxo> Setup Wars - YouTube
22:32 < heath> related: https://www.instagram.com/p/B9PRxyEHvmg/?utm_source=ig_web_copy_link
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--- Log closed Thu Mar 05 00:00:12 2020