--- Log opened Tue Mar 24 00:00:31 2020 00:18 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 240 seconds] 00:30 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 01:00 -!- HEx1 [~HEx@hexwab.plus.com] has joined ##hplusroadmap 01:58 -!- helleshin [~talinck@98.29.27.253] has joined ##hplusroadmap 02:00 -!- hehelleshin [~talinck@98.29.27.253] has quit [Ping timeout: 240 seconds] 03:19 < fenn> i suppose it was inevitable, https://nypost.com/2020/03/24/polish-residents-can-send-government-selfies-to-prove-quarantine-compliance/ 03:20 < fenn> "randomly prompted throughout the day to submit more selfies. If the users fail to respond within 20 minutes, the authorities are alerted." 03:21 < fenn> i shouldn't need to point out how this can be abused 03:39 < mrdata> indeed 04:02 -!- darsie [~kvirc@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap 04:08 < nsh> heh 04:09 < nsh> someone should give that app a security audit 04:54 -!- balrog [~balrog@unaffiliated/balrog] has quit [Ping timeout: 256 seconds] 04:56 -!- balrog [~balrog@unaffiliated/balrog] has joined ##hplusroadmap 05:01 -!- urkk [~urkk@144.243.17.95.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 05:05 -!- urkk [~urkk@27.134.239.188.dynamic.jazztel.es] has joined ##hplusroadmap 05:34 < fltrz> fenn, I hope they don't do this here, since I have smartphone compatible with european data network, I do have a cell phone but its the SMS and calling only type 05:34 < fltrz> here = Belgium 05:34 < fltrz> since I *don't* have ... 05:35 < fltrz> it's japanese, but I use it as a tablet for watching movies 05:44 < fenn> superkuh: thoughts about extracting the zinc ionophore pyrithione from shampoo as a stopgap coronavirus treatment? 05:46 < fenn> should i be telling people to start shampooing with head & shoulders? 05:47 < fenn> maybe that's a waste of precious shampoo 06:20 < nsh> what does this do? 06:27 < fenn> zinc ionophores increase the intraceullular zinc levels, and zinc ions inhibit coronavirus RNA-dependent RNA polymerase. it's one possible mechanism for why chloroquine has an antiviral effect 06:46 < fenn> .title https://www.ncbi.nlm.nih.gov/pubmed/29471083 06:46 < saxo> Imaging the penetration and distribution of zinc and zinc species after topical application of zinc pyrithione to human skin. - PubMed - NCBI 06:46 < fenn> 250x increase in skin cell zinc levels after 48hr 06:51 < fenn> seems to cause oxidative damage by inducing mitochondrial malfunction 06:51 < fenn> pretreatment with antioxidants afforded protection (in vitro) 06:56 < fenn> smearing shampoo all over your skin might increase blood levels of pyrithione enough to raise zinc levels in mucous membrane and lung epithelial cells, or it may just stay in the skin and suck away all available zinc 06:57 < fenn> best to do it only if you're also taking a zinc supplement 07:00 -!- filipepe [uid362247@gateway/web/irccloud.com/x-uidiajyisikexgcd] has joined ##hplusroadmap 07:15 -!- jenelizabeth [~jenelizab@cpc155793-brmb11-2-0-cust474.1-3.cable.virginm.net] has quit [Read error: No route to host] 07:18 -!- jenelizabeth [~jenelizab@cpc155793-brmb11-2-0-cust474.1-3.cable.virginm.net] has joined ##hplusroadmap 07:22 < nsh> ty fenn 07:23 -!- jenelizabeth [~jenelizab@cpc155793-brmb11-2-0-cust474.1-3.cable.virginm.net] has quit [Ping timeout: 250 seconds] 07:23 < nsh> a lot of folk suggestions of taking zinc, surprised this is the one that maybekinda makes sense 07:25 < fenn> zinc is also useful against influenza, another RNA respiratory virus 07:25 < fenn> everywhere i look zinc lozenges are out of stock 07:26 < fenn> and most zinc supplements 07:26 < fenn> if things get desperate we can start melting pennies and dissolving them in lemon juice :D 07:27 < fenn> i haven't seen anyone talking about flavonoids such as quercetin or EGCG 07:27 < fenn> eat your kale and red onions 07:28 -!- jenelizabeth [~jenelizab@cpc155793-brmb11-2-0-cust474.1-3.cable.virginm.net] has joined ##hplusroadmap 07:35 -!- superjen96 [~jenelizab@185.92.25.51] has joined ##hplusroadmap 07:37 -!- yashgaroth [~ffffffff@172.58.19.145] has joined ##hplusroadmap 07:39 -!- jenelizabeth [~jenelizab@cpc155793-brmb11-2-0-cust474.1-3.cable.virginm.net] has quit [Ping timeout: 256 seconds] 07:42 < nsh> speaking of flavonoids, someone sent me some cannabis oil, which i should now try, having nominally finished working 07:54 < fenn> finished nominally working* 07:55 < nsh> indeed 08:22 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 246 seconds] 08:39 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 09:15 < superkuh> https://www.brainstimjrnl.com/article/S1935-861X(20)30063-2/fulltext "Rotational field TMS: Comparison with conventional TMS based on motor evoked potentials and thresholds in the hand and leg motor cortices" 09:15 < superkuh> "...conventional TMS configurations affect primarily neurons that are aligned parallel to the induced electric field by a fixed coil, making the activation orientation-specific. A novel method termed rotational field TMS (rfTMS), where two orthogonal coils are operated with a 90° phase shift, produces rotation of the electric field vector over almost a complete cycle, and may stimulate larger portion of the neuronal population within a g 09:15 < superkuh> iven brain area." 09:29 -!- filipepe [uid362247@gateway/web/irccloud.com/x-uidiajyisikexgcd] has quit [Quit: Connection closed for inactivity] 09:31 -!- mode/##hplusroadmap [+o fenn] by ChanServ 09:31 -!- mode/##hplusroadmap [-b redlegion!*@*] by fenn 09:32 -!- redlegion [sid429547@gateway/web/irccloud.com/x-pwycrqarmydxgzbk] has joined ##hplusroadmap 09:32 -!- mode/##hplusroadmap [-o fenn] by fenn 10:45 -!- Netsplit *.net <-> *.split quits: fltrz, faceface, dingo, agile_prg3, kanzure 10:45 -!- faceface_ [~faceface@unaffiliated/faceface] has joined ##hplusroadmap 10:45 -!- Netsplit over, joins: kanzure, fltrz, agile_prg3, dingo 10:49 < kanzure> hmph 11:13 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:e9f4:57b2:ae91:a2c1] has joined ##hplusroadmap 11:33 -!- Codaraxis [~Codaraxis@ip68-5-175-208.oc.oc.cox.net] has joined ##hplusroadmap 11:35 -!- Codaraxis__ [~Codaraxis@ip68-5-175-208.oc.oc.cox.net] has quit [Ping timeout: 265 seconds] 11:58 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:e9f4:57b2:ae91:a2c1] has quit [] 12:20 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Remote host closed the connection] 12:22 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:e9f4:57b2:ae91:a2c1] has joined ##hplusroadmap 12:32 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:e9f4:57b2:ae91:a2c1] has quit [] 12:33 -!- filipepe [uid362247@gateway/web/irccloud.com/x-bhovddpurzpeertg] has joined ##hplusroadmap 12:34 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:e9f4:57b2:ae91:a2c1] has joined ##hplusroadmap 12:57 -!- mauz555 [~mauz555@2a01:e0a:56d:9090:e9f4:57b2:ae91:a2c1] has quit [] 13:28 < fenn> .title http://ncbi.nlm.nih.gov/pubmed/25050823 13:28 < saxo> Zinc ionophore activity of quercetin and epigallocatechin-gallate: from Hepa 1-6 cells to a liposome model. - PubMed - NCBI 14:16 -!- aeiousom1thing [~aeiousome@unaffiliated/aeiousomething] has joined ##hplusroadmap 14:16 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Read error: Connection reset by peer] 14:17 -!- _0bitcount [~Big_Byte@90.162.105.206] has joined ##hplusroadmap 14:47 < dingo> ugh 14:49 -!- dingo [~jq@c-71-198-233-28.hsd1.ca.comcast.net] has quit [Quit: real life wants me off irc] 15:56 < lsneff> "Here's a Blueprint for a Practical Quantum Computer" (https://spectrum.ieee.org/computing/hardware/heres-a-blueprint-for-a-practical-quantum-computer) 16:16 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 264 seconds] 16:30 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 16:32 -!- _0bitcount [~Big_Byte@90.162.105.206] has quit [Quit: Leaving] 16:45 -!- helleshin [~talinck@98.29.27.253] has quit [Read error: Connection reset by peer] 16:46 -!- helleshin [~talinck@98.29.27.253] has joined ##hplusroadmap 17:02 -!- hehelleshin [~talinck@98.29.27.253] has joined ##hplusroadmap 17:05 -!- helleshin [~talinck@98.29.27.253] has quit [Ping timeout: 246 seconds] 18:22 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 18:58 -!- darsie [~kvirc@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 250 seconds] 19:46 -!- justan0theruser [~justanoth@2600:8804:980:523:b996:c6a6:556:cf14] has joined ##hplusroadmap 19:46 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 260 seconds] 20:25 -!- yashgaroth [~ffffffff@172.58.19.145] has quit [Quit: Leaving] 20:34 -!- justan0theruser [~justanoth@2600:8804:980:523:b996:c6a6:556:cf14] has quit [Quit: WeeChat 2.7.1] 20:34 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 21:01 -!- CRM114 [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 21:05 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 264 seconds] 21:21 -!- TC [~talinck@98.29.27.253] has joined ##hplusroadmap 21:21 -!- TC is now known as Guest77698 21:22 -!- filipepe [uid362247@gateway/web/irccloud.com/x-bhovddpurzpeertg] has quit [Quit: Connection closed for inactivity] 21:24 -!- hehelleshin [~talinck@98.29.27.253] has quit [Ping timeout: 256 seconds] 21:28 -!- filipepe [uid362247@gateway/web/irccloud.com/x-ydxtyseqzojieace] has joined ##hplusroadmap 21:50 -!- hehelleshin [~talinck@98.29.27.253] has joined ##hplusroadmap 21:53 -!- Guest77698 [~talinck@98.29.27.253] has quit [Ping timeout: 256 seconds] 22:57 -!- TC [~talinck@98.29.27.253] has joined ##hplusroadmap 22:57 -!- TC is now known as Guest51849 23:02 -!- hehelleshin [~talinck@98.29.27.253] has quit [Ping timeout: 264 seconds] 23:38 -!- Livestradamus [~quassel@unaffiliated/livestradamus] has quit [Quit: I'm out.] 23:39 -!- Livestradamus [~quassel@unaffiliated/livestradamus] has joined ##hplusroadmap 23:41 -!- CRM114 is now known as Urchin --- Log closed Wed Mar 25 00:00:33 2020