--- Log opened Sat Sep 05 00:00:09 2020 00:25 -!- pompolic [~A@unaffiliated/pompolic] has quit [Ping timeout: 240 seconds] 00:29 -!- raegan [~raegan@2604:6000:cf89:ac00:8f11:d6fb:e564:417b] has quit [Quit: WeeChat 2.8] 00:32 -!- pompolic [~A@unaffiliated/pompolic] has joined ##hplusroadmap 02:23 -!- darsie [~kvirc@84-113-55-200.cable.dynamic.surfer.at] has joined ##hplusroadmap 02:54 -!- Urchin[emacs] [~user@unaffiliated/urchin] has quit [Quit: ERC (IRC client for Emacs 26.1)] 05:15 -!- CryptoDavid [uid14990@gateway/web/irccloud.com/x-lfmsmrdtvzvpefks] has joined ##hplusroadmap 05:32 -!- shawwwn [uid6132@gateway/web/irccloud.com/x-coufpbvbpeplwurd] has joined ##hplusroadmap 05:34 < kanzure> hmph 05:42 < darsie> . 06:49 -!- HumanG33k [~HumanG33k@62.147.242.8] has joined ##hplusroadmap 07:38 -!- yashgaroth [~ffffffff@172.58.19.253] has joined ##hplusroadmap 07:42 -!- shawwwn [uid6132@gateway/web/irccloud.com/x-coufpbvbpeplwurd] has quit [Quit: Connection closed for inactivity] 09:16 < kanzure> demonpore https://patents.google.com/patent/US20180328909A1/en 09:23 < yashgaroth> stanley huh 09:33 < kanzure> who knew 12:09 < kanzure> .title https://github.com/chriskiehl/Gooey 12:09 < saxo> GitHub - chriskiehl/Gooey: Turn (almost) any Python command line program into a full GUI application with one line 14:33 -!- Foxtrot[m] [mrrabbittr@gateway/shell/matrix.org/x-fintsgpviiwmbyvk] has joined ##hplusroadmap 14:34 < Foxtrot[m]> Whats up people, just here to spread the word on https://transhumanist.club slowly building more services on top of it. Cyberpunk/retrofuturist theme for services. Trying to build a community of likeminded people who are interested in building an internet to move us away from centralized services ran by massive corporations. 14:34 < Foxtrot[m]> Its not much at the moment but there's a few private community services as well once you talk with more people over at / T H E E N D / 14:58 < kanzure> i don't get it. why not just go join one of the other decentralized/federated communities community? 15:02 < kanzure> "Language models are few-shot learners" https://arxiv.org/pdf/2005.14165.pdf 15:03 < kanzure> "Ageing hallmarks exhibit organ-specific temporal signatures" https://www.nature.com/articles/s41586-020-2499-y 15:03 < Foxtrot[m]> Its a matter of making *more*, plus most I've seen don't seem to have much of a focus on providing anonymous/tor/i2p friendly mirrors of their services. The aim is to simply provide more alternatives and promote people moving from the regular internet to something like tor. Plus, its just fun. 15:04 < kanzure> "Engineered off-the-shelf therapeutic T cells resist host immune rejection" https://www.nature.com/articles/s41587-020-0601-5 15:06 < kanzure> "Imaging through highly scattering human skulls with ultrasound-modulated optical tomography" https://www.osapublishing.org/ol/abstract.cfm?uri=ol-45-11-2973 15:06 < kanzure> "Single-impulse panoramic photoacoustic computed tomography of small-animal whole-body dynamics at high spatiotemporal resolution" https://www.nature.com/articles/s41551-017-0071 15:06 < kanzure> https://chanzuckerberg.com/newsroom/czi-launches-new-effort-to-support-technology-development-in-imaging/ 15:09 < kanzure> "BRICseq (brain-wide individual animal connectome sequencing) which leverages DNA barcoding and sequencing to map connectivity" https://www.cell.com/cell/fulltext/S0092-8674(20)30624-3?rss=youwish 15:11 < kanzure> "Single cell in vivo brain optogenetic stimulation by two-photon excitation fluorescence transfer" https://www.biorxiv.org/content/10.1101/2020.06.29.179077v2 15:12 < kanzure> .tw https://twitter.com/Ben_Reinhardt/status/1277278667186544640 15:12 < saxo> I read the entire Endless Frontier Act so your eyes don't need to bleed. Thoughts here: https://benjaminreinhardt.com/the-endless-frontier-act/ // (The Endless Frontier Act is a bipartisan proposal to expand the NSF's budget by $100B over five years and explicitly add technology to its mandate.) (@Ben_Reinhardt) 15:12 < kanzure> .title https://keith.seas.harvard.edu/geoengineering-resources 15:12 < saxo> Solar Geoengineering Resources | The Keith Group 15:13 < kanzure> .tw https://twitter.com/kidd_brendan/status/1275033430422548480 15:13 < saxo> Wild to hear @a16z do a journal club on @erblabs fantastic synthetic chloroplast papers! Really fantastic discussion from @heyjudka and @lr_bio on the science and also future opportunities in #plantsynbio! #plantbioisthebestbio https://twitter.com/a16z/status/1274775078052470785 (@kidd_brendan) 15:15 < kanzure> "DreamCoder: Growing generalizable, interpretable knowledge with wake-sleep bayesian program learning" https://arxiv.org/pdf/2006.08381.pdf 15:15 < kanzure> .tw https://twitter.com/maxhkw/status/1274714943716089856 15:15 < saxo> New work from Kevin Ellis is a breakthrough for learning to synthesize programs. DreamCoder learns and extends a DSL and uses it to solve new problems faster. Rediscovers human-like languages: physical laws, vector algebra & functional programming: https://arxiv.org/pdf/2006.08381.pdf https://pbs.twimg.com/media/EbBOsspUcAIPGXV.jpg (@maxhkw) 15:15 < kanzure> .title https://www.youtube.com/watch?v=hJU5PBWCJoE 15:15 < saxo> Allen School Colloquium: Kevin Ellis (MIT) - YouTube 15:15 < kanzure> well anyway, it's a talk about that work 15:17 < kanzure> https://nintil.com/epigenetic-clocks 15:18 < kanzure> .tw https://twitter.com/davidasinclair/status/1270037664885084163 15:18 < saxo> The Conboy lab reports the ability of young blood transfusions to reverse 🐭 aging is mimicked by a simple replacement of blood with a neutral age fluid [saline + 5% albumin] with benefits in muscle, liver, and new brain cell formation (image)💪#aging https://tinyurl.com/y7y9eqmh https://pbs.twimg.com/media/EaAUYN8XYAIFCEC.jpg (@davidasinclair) 15:18 < kanzure> alright i think that means i'm caught up... 15:26 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 15:36 < fenn> .title https://judgestarling.tumblr.com/post/619829573132107776/a-short-story-by-martian-physicist-le%C3%B3-szil%C3%A1rd 15:36 < saxo> Judge Starling — A Short Story by “Martian” Physicist Leó Szilárd... 15:42 < fenn> “The Marla Gable Foundation,” a funding agency whose mission is the “retardation of scientific progress.” 15:44 < L29Ah> do sundays school qualify as an agency whose mission is the “retardation of scientific progress”? 15:44 < kanzure> all schools qualify 15:45 < Foxtrot[m]> lol 15:46 < L29Ah> kanzure: i'm not so sure: most people can't afford personalized education, and school lectures might be okay until you understand why and what do you need to aim for in your independent studies 15:47 < kanzure> if you can't afford personalized education then you probably can't afford education in the first place; but you get taxed anyway. 15:47 < L29Ah> i mean schools, not state schools 15:52 < lsneff> That's a very elitist view, kanzure 15:56 < kanzure> er, isn't it the opposite of elitist? 15:56 < kanzure> elitist would be "everyone can afford taxes and personalized education at the same time" 15:56 < kanzure> thanks for playing? 16:01 < lsneff> I'm not so sure about that 16:03 < Foxtrot[m]> This would be the view of someone absolutely out of touch with reality, not an elitist. Its definitely elitist to say if you can't get personalized education you can't be educated... 16:04 < lsneff> Thank you, Foxtrot[m] 16:08 < fenn> marblestone left Kernel.co for Google DeepMind 16:21 < fenn> http://web.mit.edu/amarbles/www/docs/fiberreflect.png 16:23 < L29Ah> wat 16:23 < L29Ah> this doesn't look like an action potential 16:28 < fenn> the electric field created during the neuron firing changes the local index of refraction in a nonlinear optical medium, and its position can be detected by the optical reflectometer 16:28 < fenn> you'd need several such fibers to get a 3D coordinate 16:29 < fenn> the fingerprint is more important than the exact coordinates anyway 16:29 < fenn> fibers are nice because they can be very narrow with no signal loss 16:29 < fenn> as opposed to wires 16:31 < fenn> probably the orange circle is the soma, and the arrows represent the traveling wave along the axon 16:34 < superkuh> Heh. The neuronal axon itself is just sucha non-linear optical medium and the scattering due to changes in refraction during the passage of the action potential were discovered back in the 1950s. 16:36 < fenn> the fiber must do total internal reflection 16:36 < fenn> that is interesting though 16:37 < superkuh> See I Tasaki for the old stuff, or T Heimberg for the modern reviews. /library/Neuroscience/Lipid Membrane/ 16:40 < fenn> it's so cool that i can just read these papers instantly 16:41 < fenn> fwiw the tasaki papers are from 1971 to 2005 16:43 < fenn> apparently there is a mechanical (acoustic) wave to go along with the electrical wave 16:44 < superkuh> Ah, I must have been thinking of the date when he discovered myelination. 16:44 < superkuh> Or, er, the method of action potential propagation in mylinated neurons. 17:01 -!- darsie [~kvirc@84-113-55-200.cable.dynamic.surfer.at] has quit [Ping timeout: 258 seconds] 17:47 < lsneff> .t https://venturebeat.com/2020/09/03/were-entering-the-ai-twilight-zone-between-narrow-and-general-ai/ 17:47 < saxo> We're entering the AI twilight zone between narrow and general AI | VentureBeat 18:24 -!- CryptoDavid [uid14990@gateway/web/irccloud.com/x-lfmsmrdtvzvpefks] has quit [Quit: Connection closed for inactivity] 18:34 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [] 18:51 < kanzure> https://www.nytimes.com/2020/09/01/science/covid-19-vaccine-diy.html 19:02 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 19:06 < kanzure> .tw https://twitter.com/TetsuyaIshii/status/1301347934210932737 19:06 < saxo> 米中英のアカデミーが #ゲノム編集 児作出を認める報告書を出す。国々が倣って解禁するとは思えないが、お墨付きを与えて第二の中国事件を生みかねない。https://www.nap.edu/catalog/25665/heritable-human-genome-editing?mc_cid=f51695d329&mc_eid=91d5144415 (@TetsuyaIshii) 19:09 < kanzure> .tw https://twitter.com/biohackinfo/status/1297984008626806784 19:09 < saxo> Bioethicists are getting out of control with their anti-CRISPR Babies propaganda. 😠 https://video.twimg.com/ext_tw_video/1297983904117329921/pu/vid/640x360/sDvSq5W1tqC9YozZ.mp4?tag=10 (@biohackinfo) 19:14 < kanzure> https://biohackinfo.com/news-alexandra-elbakyan-elon-musk-scihub-neuralink-bci/ 19:15 < kanzure> https://engineuring.wordpress.com/2010/04/25/consciousness-in-mixed-systems-merging-artificial-and-biological-minds-via-brain-machine-interface/ 19:15 < kanzure> .tw https://twitter.com/Sci_Hub/status/1283671299559239680 19:15 < saxo> fun fact: Elon Musk's Neuralink ideas about brain-machine and transhumanism is a close copy to the ideas of Sci-Hub founder Alexandra Elbakyan, that I have published in 2010: http://wp.me/pyerf-2M and http://wp.me/pyerf-3f proud to have such a prominent successor! (@Sci_Hub) 19:15 < kanzure> hmmm 19:16 < kanzure> this is the same sort of reaction that reviewer 2's have ("you didn't cite my work! you didn't do it right!") 19:16 < kanzure> or similar to it at least 19:27 < fenn> wow two people came up with the same idea, amazing! 19:27 < lsneff> Literally, people have had that idea for decades 19:27 < fenn> clearly we should have some sort of globally enforced patent system to make sure this can never happen again 19:42 < L29Ah> but Shura is anti-patent 19:48 < lsneff> Have you all noticed that the ability to problem solve is a strangely niche skill? 19:48 < L29Ah> is it a skill? 19:49 < lsneff> I'd say so 19:49 < lsneff> What would you call it instead? 19:49 < L29Ah> event 19:51 < lsneff> Well, a problem being solved is an event, sure. 19:51 < fenn> it's a skill 19:52 < fenn> it transfers between domains too 19:52 < fenn> or maybe a set of skills 19:53 < fenn> .wik TRIZ 19:53 < saxo> "TRIZ (/ˈtriːz/; Russian: теория решения изобретательских задач, teoriya resheniya izobretatelskikh zadatch, literally: 'theory of the resolution of invention-related tasks') is 'a problem-solving, analysis and forecasting tool derived [...]" - https://en.wikipedia.org/wiki/TRIZ 19:54 < fenn> this is less about debugging and more about creativity, but it's similar to what i'd call problem solving 19:54 < L29Ah> 05:52:04] it transfers between domains too 19:54 < L29Ah> [citation needed] 19:54 < fenn> ok 19:55 < fenn> i want to be clear i'm not talking about raw IQ, but rather a set of techniques such as "try changing one thing and doing it again" 19:56 < lsneff> It seems pretty clear to me that problem solving's domain _is_ between domains 19:56 < L29Ah> i'm aware of TRIZ, but it seems to be pretty much impossible to evaluate 19:56 < lsneff> Yes, that is also what I'm talking about 19:56 < L29Ah> lsneff: it seems pretty clear that "problem solving" is a class of events, while the existance of the cross-domain skill is unclear 19:58 < lsneff> How can problem solving be a class of events, other than in a lexical context? 19:58 < fenn> lsneff: i attribute it's nicheness to the educational system spoon feeding students made up bullshit "problems" where the goal is to show you paid attention in class, not to actually solve any problems 20:04 < lsneff> fenn: that seems plausible to me. 20:06 < lsneff> I can confirm that much of K-12 was unnecessary work. 20:06 < lsneff> University, slightly less so, but still the case over all. 21:44 -!- yashgaroth [~ffffffff@172.58.19.253] has quit [Quit: Leaving] 23:30 -!- darsie [~kvirc@84-113-55-200.cable.dynamic.surfer.at] has joined ##hplusroadmap --- Log closed Sun Sep 06 00:00:10 2020