--- Log opened Wed Jul 20 00:00:25 2022
00:19 < lsneff> I fondly remember the before-times, when I could buy ICs without a care in the world
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10:17 < kanzure> https://github.com/petertodd/python-bitcoinlib/pull/276
10:37 < kanzure> https://dallery.gallery/wp-content/uploads/2022/07/The-DALL%C2%B7E-2-prompt-book-v1.01.pdf
12:53 < kanzure> "DNA origami rotary ratchet motor" https://www.nature.com/articles/s41586-022-04910-y
12:55 < kanzure> ".. we arrive at a maximum torque of approximately 10 pN nm, which may be compared with the 50 pN nm that F1F0-ATPase can generate ... The estimated maximum power of our motors dissipated in friction was 250 pN nm s^−1 (62 kBT s^−1), which corresponds to the equivalent of the free energy delivered by the hydrolysis of approximately 2.5 ATP molecules per second at cellular ...
12:55 < kanzure> ...conditions."
12:58 < kanzure> "... Our motor is thus designed to be operated as a ratchet under out-of-thermal-equilibrium conditions. To elicit an asymmetric, or biased, ratcheting effect, we apply a non-rotating electric alternating current (AC) field using electrodes immersed in the liquid chamber (Fig. 1f and see also Extended Data Fig. 1). The field causes an alternating ion current flowing through the sample chamber ...
12:58 < kanzure> ...along a fixed axis. The time-averaged net force created by this external modulation is zero. There is no information supplied by the external modulation that could dictate a rotation of the motor. Instead, depending on the nature and location of energetic minima in the motor relative to the axis of the electric field, the modulation can produce a kinetic asymmetry per field cycle that causes ...
12:58 < kanzure> ...the motor to move with a preferred rotation direction"
13:19 < kanzure> i wonder if the ion current would be strong enough to disrupt other biological processes you might want the motor to be engaging in (such as DNA synthesis)
13:32 < kanzure> https://astralcodexten.substack.com/p/criticism-of-criticism-of-criticism
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15:32 < nsh> if he wasn't so halfway clever he could make a much better point with logarithmically fewer words
15:32 < kanzure> glass windows and round stones, nsh
15:33 < nsh> indeed
15:34 < nsh> but whereas i err on the side of reticence pending insight, some try to feed others with the field rather than the bread that might come from the grain that might grow from the field if it were ploughed and tilled and watered
15:36 < kanzure> were i not possessed with a purpose beyond my own i had better be a ploughman than a philosopher, yadda yadda
15:47 < nsh> it might be worth noting that the third act in Man and Superman is often not played in theatres as it's considered extraneous and its ideas implicit in the drama of the first two acts
15:48 < nsh> which is the same point i was trying to make about doing ones working out and then presenting ones conclusion while leaving the many wandering paths taken to get there as optional to the audience
15:49 < nsh> then again i didn't even know about the play until you referenced it
16:05 < nsh> (and so thank you kindly)
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17:24 < kanzure> https://blog.archive.org/2022/07/08/internet-archive-seeks-summary-judgment-in-federal-lawsuit-filed-by-publishing-companies/
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17:41 < kanzure> looks like the library of congress doesn't scan "items that are protected by copyright" https://www.loc.gov/rr/loan/illscanhome.html
18:32 < fenn> the rockwell integrated brain plan: https://thehighestofthemountains.org/images/thehighestofthemountains_brain_map_rev117_image.pdf and some quotes https://thehighestofthemountains.org/images/thehighestofthemountains_brain_quotes_rev27_image.pdf from a buggy page https://thehighestofthemountains.org/images/brainmaps.html
18:36 < kanzure> https://diyhpl.us/~bryan/papers2/neuro/cognitiveconsilience/stitched-diagram.jpg
18:58 < kanzure> hippocampus system of nonlinear equations or.. something: https://en.wikipedia.org/wiki/Hippocampal_prosthesis
18:58 < kanzure> "In fact, the patterns would even identify when the rat was about to make an error in the task.[7] Over the following ten years, Deadwyler's laboratory refined the analysis to identify the 'codes' and improved the ability to predict correct and error responses, even to the point of being able to have untrained rats perform the memory task using hippocampal stimulation with codes obtained from ...
18:58 < kanzure> ...fully trained rats.[8]"
18:58 < kanzure> [8] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872745/
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22:07 < fenn> https://koniku.com/ "Our smell cyborgs are capable of autonomously and intelligently reading the air. We engineer proteins in biological neurons to create precise protein particle interactions. The biological cells function as sensors, amplifiers and biological signal processors."
22:13 < fenn> ok there's not much on the website. it's a chip with 640 electrodes and 128 "active" neurons, and 50,000 "hidden" neurons, and they're using them as smell sensors
22:13 < fenn> seems like they're going for general brain computer interfaces, and this is a minimum viable product
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23:25 < lsneff> I wonder how far they are
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--- Log closed Thu Jul 21 00:00:26 2022