--- Log opened Mon Jul 25 00:00:30 2022
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05:09 < kanzure> hmph
05:36 < kanzure> .tw https://twitter.com/TheBlueMatt/status/1551418465466159104
05:36 < saxo> Finally gonna turn off one of the oldest Bitcoin v2 hidden services - http://nkf5e6b7pl4jfd4a.onion. It still gets a lot of traffic and various guides say to include it as an "addnode". Migrate to http://pcxlvkgabsowmrx54b5bgqglershgfchr6xavrhbfngridplzhf2pwqd.onion (mainnet) and http://gylbrk3wggb77slglnxwi3i5pwytnivzk4t4mvukybtffe2bfwfvb6yd.onion (testnet). (@TheBlueMatt)
06:35 < superkuh> RIP stable onion names worth having.
06:37 < superkuh> ~30% chance of any attempt to resolve an onion v2 address will fail these days, https://www.encryptionin.space/tracking-hsdirs-and-the-version-of-tor-they-run
06:50 < kanzure> 'starmanning' instead of steelmanning https://news.ycombinator.com/item?id=32222683
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08:03 < kanzure> https://www.amazon.com/RecZone-Reczone-Password-Vault-Return/dp/B003VV17DO
08:18 < kanzure> ah bunnie's precursor has a password manager mode https://www.crowdsupply.com/sutajio-kosagi/precursor/updates/xous-release-v0-9-9-vault-authentication-app-and-more
08:18 < kanzure> direct integration with bitwarden would be interesting
08:19 < kanzure> appear-as-usb-keyboard to type in passwords is useful but bluetooth keyboard would make more sense (if bluetooth is securable... i assume you can lay any encryption on top of it.)
08:25 < kanzure> oh that was posted a few days ago
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13:06 < ^ditto> [freenode] <tristan-roberts> hey... what is the main h+ channel on this server?
13:13 <+gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e1a4d650 Stacie Waleyko: Fix typo: transacton -> transaction >> http://diyhpl.us/diyhpluswiki/transcripts/scalingbitcoin/hong-kong/overview-of-bips-necessary-for-lightning/
13:13 <+gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=cdb5cee8 Bryan Bishop: Merge pull request #240 from satsie/master >> http://diyhpl.us/diyhpluswiki/
13:13 <+gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=74a14405 Bryan Bishop: Merge remote-tracking branch 'github/master' >> http://diyhpl.us/diyhpluswiki/
13:15 < kanzure> .tw https://twitter.com/szeloof/status/1551582929138192387?cn=ZmxleGlibGVfcmVjcw%3D%3D&refsrc=email
13:15 < saxo> Ends in 12 hours - transmission electron microscope TEM (wokring) // I'm gonna pass, one of you should get it, about 100x cheaper than MSRP 🤑🤑🤑 // https://www.govdeals.com/index.cfm?fa=Main.Item&itemid=1358&acctid=2687 https://pbs.twimg.com/media/FYhUAVvWQAAygot.jpg (@szeloof)
13:15 < kanzure> $5000.. anyone want it?
13:19 < muurkha> nice
13:19 < muurkha> Muaddib: how would you make diethyl ether without sulfuric acid?
13:19 < Muaddib> muurkha: I'd just make it with ethanol; that would work just fine.
13:19 < muurkha> Muaddib: sure, but how do you convert the ethanol to diethyl ether?
13:19 < Muaddib> muurkha: I'd just use a process called "sublimation" ;)
13:21 < muurkha> Muaddib: sublimation can purify a substance once you have made it, but it doesn't cause chemical changes like the one needed in this case
13:21 < Muaddib> muurkha: oh, you're right. I forgot about that.
13:24 < ^ditto> [freenode] <Damian> Anyone online right now?
13:26 < muurkha> uh, does "freenode" still exist?
13:27 < ^ditto> [freenode] <Damian> #freenode
13:45 < L29Ah> Muaddib: what is freenode?
13:45 < Muaddib> L29Ah: I'm not sure.
13:45 < L29Ah> Muaddib: me too
13:45 < Muaddib> L29Ah: yeah, maybe it's a secret you need to pay to know
13:47 < L29Ah> kanzure: so what happens if it times out?
13:48 < L29Ah> maybe one could wait patiently in a pickup truck near the dumpster
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14:20 < fenn> .title https://groups.google.com/g/diybio/c/tsN60rJ2rRA
14:20 < saxo> Looking for partner or group for DIY TPE
14:21 < fenn> therapeutic plasma exchange (plasmapheresis)
14:21 < fenn> .title https://www.aging-us.com/article/103418/text
14:21 < saxo> Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin | Aging
14:21 < fenn> conboy, conboy, et al.
14:24 < L29Ah> tl;dr, i'm considering doing this, but that means i have to bribe someone at the blood bank, and they will probably refuse as in my experience medical professionals are very anal about following their protocols
14:24 < L29Ah> the plasma removal thing
14:24 < muurkha> L29Ah: can't you get needles?
14:24 < L29Ah> or do it gradually as continuous plasma donations, but not sure if it makes as much sense
14:25 < fenn> blood donors do tend to live longer
14:25 < fenn> (matched controls)
14:25 < L29Ah> muurkha: i don't have problems with needles, i need a membrane to get back my blood cells
14:25 < muurkha> oh interesting, fenn
14:25 < L29Ah> fenn: survivor bias
14:25 < fenn> L29Ah: please explain?
14:25 < muurkha> L29Ah: hmm, does a centrifuge kill them?
14:26 < muurkha> I don't know anything about plasma donation
14:26 < L29Ah> fenn: sick people aren't allowed to do blood donations
14:26 < fenn> that's why it's important to have matched controls
14:26 < L29Ah> muurkha: doing a sterile centrifuge thing would be even more annoying
14:26 < L29Ah> not sure if unfeasible
14:27 < fenn> .title https://onlinelibrary.wiley.com/doi/abs/10.1111/trf.13205
14:27 < saxo> Just a moment...
14:27 < fenn> "Blood donation and blood donor mortality after adjustment for a healthy donor effect"
14:28 < L29Ah> fenn: nice, thanks
14:29 < L29Ah> so the bias is only 60%
14:29 < fenn> is 7.5% reduced mortality a big or small effect?
14:30 < fenn> regular exercise is ~10-40% depending on how much you do
14:31 < L29Ah> in five years?
14:31 < muurkha> 7.5% might be a result of imperfectly matched controls
14:32 < muurkha> if it's real it would surely be worth a lot
14:32 < fenn> let's call exercise a 30% reduction in mortality
14:33 < L29Ah> in five years?
14:33  * L29Ah doesn't quite understand the methodology or how it compares with hazard ratios of aging-associated diseases
14:35 < fenn> so and so speculates about iron level reduction due to blood donation
14:36 < L29Ah> blood donation sucks, it spends your adaptive immunity and oxygen-carrying capacity (and likely related hayflick stuff), among other things
14:36 < L29Ah> plasma donation, on the other hand, is much cheaper (but much more time consuming)
14:37 < fenn> tristan-roberts, Damian, we have moved to libera.irc.chat
14:37 < fenn> er.. derp
14:37 < fenn> tristan-roberts, Damian, we have moved to irc.libera.chat
14:38 < L29Ah> and you can't remove much plasma even if you do blood donations continuously as allowed by medical protocols, as the removed amount is tiny and replenishment periods are long
14:38 < L29Ah> s/plasma/aging-relevant & contents/
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17:13 < kanzure> http://www.cyclify.com/wiki/images/a/af/Von_Neumann_Probabilistic_Logics_and_the_Synthesis_of_Reliable_Organisms_from_Unreliable_Components.pdf
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17:40 < kanzure> https://www.cs.unm.edu/~saia/talks/reliable-from-unreliable.pdf
17:52 < kanzure> "In the old way of doing things, we treat our servers like pets, for example Bob the mail server. If Bob goes down, it’s all hands on deck. The CEO can’t get his email and it’s the end of the world. In the new way, servers are numbered, like cattle in a herd. For example, www001 to www100. When one server goes down, it’s taken out back, shot, and replaced on the line."
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--- Log closed Tue Jul 26 00:00:31 2022