--- Log opened Fri Oct 07 00:00:40 2022 00:21 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has quit [Read error: Connection reset by peer] 02:46 -!- qnexvr [~darsie@84-113-55-200.cable.dynamic.surfer.at] has joined #hplusroadmap 03:03 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has joined #hplusroadmap 04:44 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has quit [Ping timeout: 268 seconds] 05:00 -!- yashgaroth [~ffffffff@2601:5c4:c780:6aa0::1909] has joined #hplusroadmap 07:04 < jrayhawk> https://simonwillison.net/2022/Sep/30/action-transcription/ should i implement something like this for gnusha 07:25 < kanzure> it would dump a text file somewhere for a video? 07:26 < kanzure> .tw https://twitter.com/chaosprime/status/1578258851077541888 07:26 < saxo> Ethics Anonymous // the first step is admitting you have a trolley problem (@chaosprime) 07:26 < kanzure> .tw https://twitter.com/kanzure/status/1578385340456386562 07:26 < saxo> @chaosprime I don't have a trolley problem, I have a trolley solution. (@kanzure, in reply to tw:1578258851077541888) 07:26 < kanzure> computer, earl grey tea, award winning, top tea on tea station, tea of the year, london times voted best tea, hot 07:47 < muurkha> haha 08:13 < jrayhawk> yeah, i would probably just shove it in a fork of the diyhpl.us wiki that you can rebase into the main one 08:15 < kanzure> might be a fun little project, but it might also take away my transcripts gimmick, so go for it 08:16 < jrayhawk> i wonder if i should prioritize youtube captions or whisper 08:17 < jrayhawk> por qué no los dos 09:00 -!- luna__ [~luna@82-132-229-235.dab.02.net] has joined #hplusroadmap 09:02 -!- luna__ [~luna@82-132-229-235.dab.02.net] has quit [Read error: Connection reset by peer] 09:03 -!- luna__ [~luna@2a01:4c8:46:b1ff:459b:cbb0:9e9d:73d5] has joined #hplusroadmap 09:03 -!- luna_ [~luna@user/luna/x-4729771] has quit [Ping timeout: 250 seconds] 09:27 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has joined #hplusroadmap 10:25 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has quit [Read error: Connection reset by peer] 10:40 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has joined #hplusroadmap 11:23 -!- spaceangel [~spaceange@ip-78-102-216-202.bb.vodafone.cz] has joined #hplusroadmap 12:48 -!- oxphi [~oxphi@107.181.189.45] has joined #hplusroadmap 14:25 -!- codaraxis__ [~codaraxis@user/codaraxis] has joined #hplusroadmap 14:29 -!- codaraxis [~codaraxis@user/codaraxis] has quit [Ping timeout: 260 seconds] 15:37 -!- luna__ is now known as luna_ 15:37 -!- luna_ [~luna@2a01:4c8:46:b1ff:459b:cbb0:9e9d:73d5] has quit [Changing host] 15:37 -!- luna_ [~luna@user/luna/x-4729771] has joined #hplusroadmap 15:42 -!- spaceangel [~spaceange@ip-78-102-216-202.bb.vodafone.cz] has quit [Remote host closed the connection] 15:52 -!- oxphi [~oxphi@107.181.189.45] has quit [Quit: Client closed] 16:08 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has quit [Read error: Connection reset by peer] 16:09 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has joined #hplusroadmap 16:28 < muurkha> hey, https://simplifier.neocities.org/index.html is a lot like fenn's Made from Scratch wiki 16:59 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has quit [Read error: Connection reset by peer] 17:06 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has joined #hplusroadmap 17:16 -!- codaraxis___ [~codaraxis@user/codaraxis] has joined #hplusroadmap 17:20 -!- codaraxis__ [~codaraxis@user/codaraxis] has quit [Ping timeout: 268 seconds] 17:23 -!- qnexvr [~darsie@84-113-55-200.cable.dynamic.surfer.at] has quit [Ping timeout: 268 seconds] 18:27 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has quit [Read error: Connection reset by peer] 18:39 -!- yashgaroth [~ffffffff@2601:5c4:c780:6aa0::1909] has quit [Quit: Leaving] 18:46 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has quit [Ping timeout: 268 seconds] 18:51 -!- codaraxis__ [~codaraxis@user/codaraxis] has joined #hplusroadmap 18:54 -!- codaraxis___ [~codaraxis@user/codaraxis] has quit [Ping timeout: 268 seconds] 19:53 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has joined #hplusroadmap 22:10 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has joined #hplusroadmap 23:17 < nmz787> .title https://platform.efabless.com/projects/1268 23:17 < saxo> Project Detail | Efabless 23:18 < nmz787> "Nanopore-based DNA sequencing is a unique, scalable technology, utilized to identify nucleotides (i.e., A, C, G, T) according to the pico-ampere-sized current fluctuations induced by the passage of a DNA strand through a like-sized molecular sensor (i.e. a “nanopore”). This approach, a so-called “3rd Generation” sequencing technology, entered the market in 2014, and is, by certain key 23:18 < nmz787> measures, at least 1000X better than incumbent methods. For example, its main components fit in the palm of one’s hand (a volumetric footprint about 1000X smaller than established machines) and it has demonstrated the ability to process contiguous DNA strands well in excess of 100,000 nucleotides in length. Critical to the success and improvement of nanopore-based DNA sequencing machines are 23:18 < nmz787> improvements in the semiconductor systems that process the pico-ampere-sized currents that they generate. There are at least two key parts to this, i) a multi-channel digital readout integrated circuit (DROIC), that amplifies, filters, and digitizes the current measurements from multitudes of arrayed nanopore sensors, and ii) a bioinformatics processing unit (BPU) that processes the gathered data in 23:18 < nmz787> order to extract biologically relevant information. In this proposal we endeavor to produce a chip that has both a DROIC and BPU in the same substrate. The intent of this effort is to introduce a technology that, by virtue of even more aggressive miniaturization will make DNA sequencing more mobile, cheaper, and more applicable to a broader array of applications." 23:18 < nmz787> https://github.com/EMIL-YORKU/SensSeq 23:18 < nmz787> .title 23:18 < saxo> GitHub - EMIL-YORKU/SensSeq: A mixed-signal system on chip for nanopore-based DNA sequencing 23:20 < nmz787> This design contains a mixed-signal readout array and a Bioinformatics Processing Unit that: Amplifies the pico-ampere-range current signals; Filters high frequecy contents; Samples the analog input; Digitizes the samples with SAR ADCs; Stores the digital data in a memory; Read the memory and analyse the data to identify the DNA sequence 23:21 -!- Malvolio [~Malvolio@idlerpg/player/Malvolio] has quit [Read error: Connection reset by peer] 23:25 < nmz787> "The proposed DROIC, consumes an area of 3×2 mm2 with 30 parallel-operated channels. The size of each channel is 320×220 μm2 in 130-nm CMOS Technology. Besides, the respective chip size of BPU RISC-V core, I$, and D$ cache is about 3.36×2.83 mm2, 3.06×2.4 mm2 and 3.108×3.06 mm2 in 130-nm CMOS. The DROIC and BPU share approximately 332 I/O pads that their size is 0.3×0.27 mm2. Figure. 4 23:25 < nmz787> illustrates the detailed sizing of the system, touched upon earlier." 23:25 < nmz787> hmm, something needs done about the IO pad count 23:30 < nmz787> kanzure: there's your chip team/project to fund 23:34 < nmz787> the lead professor https://www.eecs.yorku.ca/~magiero/ 23:56 < nmz787> https://arxiv.org/pdf/2110.01937.pdf 23:56 < nmz787> https://arxiv.org/pdf/2110.01937.pdf 23:56 < nmz787> Nanopore-Based DNA Sequencing Sensors and CMOS Readout Approaches --- Log closed Sat Oct 08 00:00:41 2022