--- Log opened Sat Feb 25 00:00:54 2023
00:32 -!- stipa_ [~stipa@user/stipa] has joined #hplusroadmap
00:34 -!- stipa [~stipa@user/stipa] has quit [Ping timeout: 265 seconds]
00:34 -!- stipa_ is now known as stipa
00:35 -!- cthlolo [~lorogue@77.33.23.154.dhcp.fibianet.dk] has joined #hplusroadmap
02:18 -!- stipa_ [~stipa@user/stipa] has joined #hplusroadmap
02:20 -!- stipa [~stipa@user/stipa] has quit [Ping timeout: 255 seconds]
02:20 -!- stipa_ is now known as stipa
02:30 -!- stipa_ [~stipa@user/stipa] has joined #hplusroadmap
02:32 -!- stipa [~stipa@user/stipa] has quit [Ping timeout: 252 seconds]
02:32 -!- stipa_ is now known as stipa
07:04 -!- o-90 [~o-90@gateway/tor-sasl/o-90] has joined #hplusroadmap
07:06 -!- o-90 [~o-90@gateway/tor-sasl/o-90] has quit [Client Quit]
12:38 < Mabel> https://www.youtube.com/watch?v=Z_ZGq8Tah0k
12:39 < Mabel> .t
12:39 < Mabel> .title
12:40 < Mabel> This Machine Grows Living Flesh!! | The Thought Emporium | 13:16
13:09 -!- cthlolo [~lorogue@77.33.23.154.dhcp.fibianet.dk] has quit [Read error: Connection reset by peer]
14:43 < kanzure> another emscripten port of opencascade https://github.com/kovacsv/occt-import-js
14:44 < kanzure> "occt-import-js that compiles only a minimal set of code from OCCT to open step, iges and brep files"
16:09 -!- luna_ [~luna@2a01:4c8:66:155f:d8ef:24a9:4955:9057] has joined #hplusroadmap
16:09 -!- luna_ [~luna@2a01:4c8:66:155f:d8ef:24a9:4955:9057] has quit [Changing host]
16:09 -!- luna_ [~luna@user/luna/x-4729771] has joined #hplusroadmap
16:14 < kanzure> looks like conjecture is working on human brain simulation (not emulation) https://www.lesswrong.com/posts/ngEvKav9w57XrGQnb/cognitive-emulation-a-naive-ai-safety-proposal  or i might be misunderstanding
17:00 < kanzure> cool to see this still online but it looks very broken https://internal-www.frontiersin.org/files/cognitiveconsilience/index.html
17:09 < kanzure> https://en.wikipedia.org/wiki/Axo-axonic_synapse
17:35 < kanzure> https://www.lesswrong.com/posts/vJFdjigzmcXMhNTsx/simulators#Simulators
18:06 < kanzure> https://longevity.technology/news/gameto-licenses-wyss-technology-for-growing-human-ovaries/
18:09 < kanzure> "Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression" https://elifesciences.org/articles/83291
18:19 < kanzure> "... Whereas efficient protocols exist for generating human primordial germ cell-like cells (hPGCLCs) from human induced pluripotent stem cells (hiPSCs), a method of generating granulosa cells has been elusive. Here, we report that simultaneous overexpression of two transcription factors (TFs) can direct the differentiation of hiPSCs to granulosa-like cells. We elucidate the regulatory effects ...
18:19 < kanzure> ...of several granulosa-related TFs and establish that overexpression of NR5A1 and either RUNX1 or RUNX2 is sufficient to generate granulosa-like cells."
18:19 < kanzure> doesn't look like any oocytes generated tho
18:39 -!- Mabel [~Malvolio@idlerpg/player/Malvolio] has quit [Ping timeout: 255 seconds]
19:15 -!- Mabel [~Malvolio@idlerpg/player/Malvolio] has joined #hplusroadmap
19:35 < fenn> why is it always george church
19:46 < kanzure> nobody else bothers
20:01 -!- codaraxis [~codaraxis@user/codaraxis] has joined #hplusroadmap
22:56 -!- Mabel is now known as PLUFISCT
23:03 -!- PLUFISCT is now known as SNRGTTLL
23:33 -!- codaraxis [~codaraxis@user/codaraxis] has quit [Quit: Leaving]
23:50 -!- SNRGTTLL is now known as CVDFNSTR
--- Log closed Sun Feb 26 00:00:55 2023