--- Log opened Mon Apr 03 00:00:21 2023
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06:33 < docl> https://visualpde.com
06:33 < hprmbridge> kanzure> neat.
09:48 < stipa> https://english.elpais.com/science-tech/2023-04-02/one-of-the-worlds-most-cited-scientists-rafael-luque-suspended-without-pay-for-13-years.html
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13:10 < kanzure> https://markov.bio/biomedical-progress/
13:15 < kanzure> "just throw more compute at it"- maybe, but we can't do large-scale human experimentation fast enough, or they certainly won't let you do the interesting experimentation, and also you might run out of humans or animals (but for cells or lower scale objects like protein folding or other machine learning tasks it could probably work)
13:16 < kanzure> "To which the optimist says: we’ve been hamstrung by regulation and only recently developed the experimental tools necessary to do real biomedical research. But now that these tools have arrived, they will change the game. We might even dare to say these tools, combined with advances in software, enable a qualitatively different type of experimental biomedical research. Biomedicine will ...
13:16 < kanzure> ...become a “data-driven discipline”."
13:17 < kanzure> "But the optimist is begging the question. They assume progress in biological research will naturally lead to progress in biomedical outcomes, but we’ve repeatedly seen this isn’t the case: our biological research has (apparently) advanced tremendously over the past twenty years, yet this hasn’t translated into similarly tremendous medical results, despite all predictions to the ...
13:17 < kanzure> ...contrary."
13:17 < kanzure> "Yet the mechanistic mind is confident this will change. This is the mechanistic mind’s translational conceit: that accumulating experimental knowledge and building ever-more reductionistic models of biology will eventually lead to cures for disease. Once we carve nature at the joints (i.e., discover the ground-truth mechanistic structure of biological systems, expressible in human-legible ...
13:17 < kanzure> ...terms), the task of translation will become easy. Through understanding nature, we will learn how to control it."
13:19 < hprmbridge> kanzure>  https://cdn.discordapp.com/attachments/1064664282450628710/1092543964093096087/image.png
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16:18 < fenn> anywhere USA, 2024 (the electric state) https://64.media.tumblr.com/b404a3f45943a8a2a45164f55994715d/tumblr_opqea0Pklz1rc69zjo7_1280.jpg
16:36 < fenn> from ground level https://64.media.tumblr.com/384ab0f51dafee302387bb956b6e2f88/tumblr_o9f2tz2Ik31rc69zjo1_1280.jpg
16:40 < hprmbridge> kanzure> some rfdiffusion stuff https://mobile.twitter.com/sokrypton/status/1642923407200116738
17:39 < pasky> ahh I do have a thing for Simon Stalenhag
17:40 < hprmbridge> lachlan> very much recommend acquiring his books
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18:28 < hprmbridge> kanzure> "CaSCaDE: (Time-Based) Cryptography from Space Communications DElay" https://eprint.iacr.org/2023/405
18:37 < nsh> aha, ty kanzure 
18:37 < nsh> i've been waiting or this
18:37 < nsh> (since a conversation with zooko about 8 years ago)
18:56 < muurkha> heh
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--- Log closed Tue Apr 04 00:00:22 2023