--- Log opened Wed May 10 00:00:56 2023
--- Day changed Wed May 10 2023
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02:52 < L29Ah> fenn: no need for a monastery for a lard candle
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05:55 < hprmbridge> kanzure> "birthgap" https://youtu.be/A6s8QlIGanA
05:55 < Muaddib> [A6s8QlIGanA] Birthgap - Childless World PART 1 (English Version) (50:29)
06:45 < kanzure> "international common mechanism for DNA synthesis screening" https://www.youtube.com/watch?v=_ykml6nmXmQ  (avoid)
06:56 < alethkit> kanzure: Do we actually *need* DNA synthesis, or is XNA enough for non-therapeutic purposes?
06:57 < alethkit> (I can actually get to a hackspace with hardware now, so if there's any wet work that needs to be done, I would like to know!)
06:58 < kanzure> yes we need dna synthesis
07:09 < alethkit> Is this for literal von neumann clones?
07:10 < kanzure> no you can do von neumann clones without much DNA synthesis
07:11 < kanzure> DNA synthesis can be used for all kinds of things- instead of doing 10,000 CRISPR edits, you can just do a single synthesis of DNA
07:11 < kanzure> imagine for each new line of code you wrote for your computer you had to pay $5,000 and wait 3 months? that's where we're at with biology right now.
08:46 < kanzure> an article proposing more regulation for human embryo work https://www.nature.com/articles/d41586-023-01550-8
08:54 < kanzure> https://a16z.com/2023/05/09/its-time-to-build-for-america-announcing-our-500m-commitment-to-companies-building-in-american-dynamism/
09:09 < alethkit> I guess my concern is that even if we do have DNA synthesis, there's probably a bunch of weird spooky effects that we get from a DNA base
09:09 < alethkit> but the methods for DNA and XNA synthesis would be similar, right?
09:11 < kanzure> i don't understand your concern yet
09:11 < kanzure> we should be building lots of synthetic genes and proteins and organisms
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10:09 < kanzure> we need a youtube poop/deepfake parody of this video- it's a hilarious post-modern take on molecular biology https://www.youtube.com/watch?v=W1_KEVaCyaA
10:10 < kanzure> (in case any mistakes this video as serious, there are several hundred obvious flaws in their reasoning and their insane interest in a specific 150aa protein)
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16:27 < hprmbridge> kanzure> more TSMC/ASML https://twitter.com/mayfer/status/1656166298806816769
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18:39 < fenn> it's not a postmodern take, it's a deliberately ignorant take
18:39 < hprmbridge> kanzure> are you sure? it might be someone's hilarious art project.
18:41 < fenn> sadly it's not
18:41 < fenn> i agree that it is hilarious
18:42 < hprmbridge> kanzure> the likelihood of someone like you stringing that sentence of words together through something like an electronic communication network is 10^4096 so therefore you didn't actually.
18:42 < fenn> "Biola University is a private, nondenominational, evangelical Christian university" ought to give you a hint why they put so much effort into this
18:43 < hprmbridge> kanzure> what's more interesting is the theory that a specific 150aa protein is specifically important; you could invalidate this by trying to find a functional mutant.
18:43 < fenn> their worldview is that everything is already perfect, so a functional mutant is an oxymoron
18:44 < hprmbridge> kanzure> yeah but how would you justify a specific protein other than post facto?
18:45 < hprmbridge> kanzure> if an amoeba transported just one atom of a star across the galaxy, it would take twenty billion trillion trillion trillion trillion trips to move a star. these are facts!
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18:52 < fenn> twenty million trillion trillion trillion trillion trillion trillion years
18:54 < fenn> twelve hundred million trillion trillion trillion trillion trips
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19:21 < hprmbridge> kanzure> that's a lot of trips
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--- Log closed Thu May 11 00:00:57 2023