--- Log opened Sat May 13 00:00:59 2023
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04:06 < hprmbridge> msnewgooty> Probably more feasibly: https://pubmed.ncbi.nlm.nih.gov/26351909/
04:07 < hprmbridge> msnewgooty> Interestingly, ancestral reconstruction tends to make things more thermo stable. The hypothesis is that the earth was hotter. Could be an artifact
04:07 < hprmbridge> msnewgooty> Useful for diversifying proteins. Luke/David did it for base editors
04:07 < hprmbridge> msnewgooty> https://pubmed.ncbi.nlm.nih.gov/29813047/
04:13 < kanzure> or maybe dino droppings floating around in space
04:13 < kanzure> unfortunately the half life of DNA is not so promising
04:13 < kanzure> on the other hand, there's one thing that organic lifeforms are good at, and that's the overproduction of DNA and spraying it around everywhere
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05:43 < superkuh> Reminds me of Kurt Vonegut's "The Big Space Fuck".
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07:08 < nsh> (DNA doesn't have a half-life because DNA does not decay exponentially)
07:09 < nsh> (and indeed is conspicuously otherwise characterised)
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08:09 < kanzure> "521 year half life" https://www.nature.com/articles/nature.2012.11555
08:14 < nsh> certainly reflective of the assumption, just not necessary the observation of the phenomenon being assumed, but i may indeed be wrong
08:15 < nsh> if i read that something that was dated twice as old as something had half the number of peptide links intact then yes, that would demonstrate the behaviour
08:16 < nsh> but unless i'm missing something that is a report of a single data point
08:16 < nsh> maybe worth reading the paper though
08:17 < nsh> sorry, it does say specimens
08:19 < nsh> of course that's not living DNA. DNA in organisms is self-evidently not subject to that kind of decay (due to replication)
08:20 < nsh> but you might be right about expected decay behaviour in space
09:05 < nsh> (plus sadly expecting scientists to do statistic right is not necessarily always a safe bet. the paper gives an r^2 value for the exponential decay model fit. https://statisticsbyjim.com/regression/r-squared-invalid-nonlinear-regression/)
09:06 < nsh> there was a recent R4 segment on how much of an uphill struggle it is to get people to engage even in civil discussion of possible scientific malpractice, let alone correct it 
09:06 < nsh> .t https://www.bbc.co.uk/programmes/m001lqvg
09:06 < EmmyNoether> BBC Radio 4 - The Truth Police
09:07 < nsh> otoh if the things that are causing the molecular links to decay are modelled exponentially (e.g. radiation) it's not a bad hypothesis 
09:08 < nsh> though i'm not even sure about that
09:17 < kanzure> could you decide if you believe in sent-day dino dna or not
09:19 < nsh> i'm relative confident about the existence of chicken :)
09:20 < nsh> and that things can be better or worse preserved that once were part of organisms that evolved into chicken
09:21 < nsh> and that aspiring to the ideal of the scientific method is a noble endeavour
09:21 < nsh> and that most do not attain that ideal, nor any others
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13:33 < hprmbridge> nmz787> Nsh DNA replication doesn't say anything about preventing degradation of the parent/original-DNA
13:34 < hprmbridge> nmz787> DNA in living organisms is also just as susceptible to degradation. The fact that cells expend energy is a testament to working against that entropy
13:35 < hprmbridge> nmz787> If the molecule gets repaired, I don't think it qualifies as being the original molecule anymore
13:53  * nsh nods
14:08 < muurkha> the Genome of Theseus
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17:02 < fenn> "the mains hum signal is treated as if it were a time-dependent digital watermark that can help identify when the recording was created, detect edits in the recording"
17:02 < fenn> .wik Electrical network frequency analysis
17:02 < EmmyNoether> "Electrical network frequency (ENF) analysis is an audio forensics technique for validating audio recordings by comparing frequency changes in background mains hum in the recording with long-term high-precision historical records of mains frequency changes from a database." - https://en.wikipedia.org/wiki/Electrical_network_frequency_analysis
17:04 < fenn> "ENF signatures from the visual stream and the ENF signature from the audio stream in a given video should match"
17:34 < nsh> heh, neat
17:35 < muurkha> nsh: sorry I didn't tell you about this earlier
17:36 < nsh> np :)
18:51 < kanzure> https://discourse.nixos.org/t/developing-a-system-that-replaces-nix-remote-build/22388
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--- Log closed Sun May 14 00:00:00 2023