--- Log opened Mon May 29 00:00:14 2023
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15:42 < kanzure> hmph
16:14 < kanzure> https://www.npr.org/sections/health-shots/2023/05/27/1177191913/sperm-or-egg-in-lab-breakthrough-in-reproduction-designer-babies-ivg
16:15 < kanzure> https://www.fda.gov/news-events/press-announcements/fda-approves-first-its-kind-intentional-genomic-alteration-line-domestic-pigs-both-human-food
16:16 < kanzure> alpha-gal "galsafe" pigs
16:17 < kanzure> "Generation of functional oocytes from male mice in vitro" https://www.nature.com/articles/s41586-023-05834-x
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17:40 < rumdumpster> Hello. Hope I'm not interrupting any chats or frustrating anyone by coming in to ask questions that aren't directly related to the channel topic, but this is the closest place I can think of.
17:42 < rumdumpster> I've been curious about neuronal adaptation and a friend's (who is a biology major and worked in a lab) claim that most neurons are "designed" (genetically) to respond to certain stimuli, thereby creating "places" in the brain for processing certain things.
17:43 < rumdumpster> My question is basically this: Is the genetic component really about being a set of neuronal structures that respond to a specific stimulus, or is it really that genetically, those neurons form in that area, which happens to be spatially related between two other parts of the network, and therefore it receives signals and specializes on those signals because of the spatial variation to the
17:43 < rumdumpster> sources and sinks of those signals?
17:45 < rumdumpster> Do neurons respond morphologically to all connections, not just "sources," or is there even a directional aspect to synapses? If places in the brain were really little factory workers (like fordist psychology believed) with little jobs to pass down to each other, or if places in the brain were computational engines (like modern psychologists suspiciously believe--see the pattern?), then
17:45 < rumdumpster> directionality would absolutely matter, and "results" would be in one point for the next, right?
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18:25 < muurkha> dunno
18:35 < kanzure> rumdumpster: all of the above. there are indeed certain types of neurons that exhibit certain behavior and you can physiologically characterize them (field of neurophysiology).
18:37 < muurkha> we do know that once a synapse is in existence it does have a directionality
18:39 < muurkha> axons can carry action potentials in either direction but any particular axon generally carries them in only one direction
18:41 < kanzure> .gpt4 -c is it true that synaptic vesicles don't transport backwards like muurkha says?
18:42 < kanzure> yeah pretty sure this is a thing
18:43 < muurkha> I didn't say anything about synaptic vesicles
18:44 < muurkha> possibly because I don't know what they are
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21:01 < fenn> rumdumpster: as far as the cortex goes, it's mostly the latter: "neurons form in that area, which happens to be spatially related between two other parts"
21:01 < fenn> you can surgically rewire eyes and ears in an embryo to be swapped and they still work fine
21:03 < fenn> the individual neurons don't know what "kind" of signal they're processing
21:04 < fenn> i don't know how instincts works
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23:26 < rumdumpster> fenn: do you have a link to that paper? my friend is a stickler. ;P I am really interested in those, and I literally thought I read that paper as well, and that's why I think the same you do
23:26 < rumdumpster> So I would like to know where I get that
--- Log closed Tue May 30 00:00:15 2023