--- Log opened Mon Aug 14 00:00:28 2023
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12:30 < fenn> PSA: keep SAM-e in heat sealed bags because ziploc isn't good enough to block moisture
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12:42 < muurkha> SAM-e?
12:42 < muurkha> I don't think heat sealing really addresses the problem
12:42 < muurkha> the water is presumably diffusing in through the thin plastic walls, not through the enormously longer and narrower path through the ziploc seal
12:43 < muurkha> if you heat-seal a ziploc bag, which is a thing you can do with enough care at setting the temperature, you'll have exactly the same problem
12:45 < muurkha> what you need is a material that more effectively blocks the diffusion of water.  aluminum is the usual choice, but some "filled resin systems" (aka plastics) use bentonite instead
12:55 < fenn> you could be right
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12:55 < fenn> there are other heat sealable polymers that block moisture much better than polyethylene
12:59 < fenn> i guess you are talking about something like this https://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra10333a
12:59 < fenn> but some polymers are just less permeable to start with
13:00 < muurkha> yes, exactly
13:00 < muurkha> polyethylene is indeed unusually bad but you will be hard pressed to find a heat-sealable polymer that is *good* at blocking moisture
13:00 < muurkha> what's SAM-e?
13:01 < fenn> a vitamin involved in methylation
13:01 < muurkha> aha
13:51 < CNOT> during surgery with narcosis, 1/3 of all patients could be awake, but not remember it afterwards. only about 0.2% say they remember anything afterwards. it gives paralysis and forgetfulness, and only maybe puts the mind into 'sleep'
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14:10 < fenn> do they also do local anesthetic just in case?
14:11 < fenn> or do we all pretend that torture doesn't matter because you forget that it happened?
14:13 < fenn> i'm pretty sure you could easily detect with EEG the difference between a body that's aware of being stabbed and burned repeatedly, and one that's not aware
15:51 < muurkha> it's an interesting question
15:53 < muurkha> more nightmare-inducing: sometimes muscle relaxants produce paralysis, so the patient can't say or do anything even though they're acutely aware of what's happening
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17:18 < fenn> there is A LOT of chinese AI stuff
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20:26 < hprmbridge> Eli> You could try doy packs. Works for hygroscopic substances. How do you like the SAMe?
20:26 < hprmbridge> Eli> Couldn’t you detect this with a heart rate monitor?
21:13 < fenn> anesthesia directly affects heart rate
21:14 < fenn> i only tried the SAMe once. it made me have no appetite all day, and no other noticeable effect
21:14 < fenn> i sampled a few pills from a friend, so i didn't lose much. they're about a dollar each
21:19 < jrayhawk> appetite loss is common with dopaminergics; just gotta get in the habit of eating anyway
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--- Log closed Tue Aug 15 00:00:29 2023