--- Log opened Fri Aug 25 00:00:39 2023
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05:12 < hprmbridge> kanzure> https://blog.torproject.org/introducing-proof-of-work-defense-for-onion-services/
05:20 < hprmbridge> kanzure> https://blog.opdup.com/2023/08/22/frost-for-braidpool.html
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07:04 < kanzure> .gpt describe the possible structure of the resulting protein from amino acid structures like RELLEVVEPEVLQDSL, GVLMEVEEPEVLQDSL, QELPEVKEQEIPEDSV, QELLEVEEQEVPENSL, RNLQESEEEEAPQESW, RNLQESEEEEAPQESW
07:04 < gptpaste> ​It is not possible to accurately predict the structure of a protein based solely on its amino acid sequence. The final structure of a protein is determined by various factors such as the folding pattern, interactions with other molecules, and environmental conditions. However, it can be inferred that these amino acid sequences may contain alpha-helices and beta-sheets due t - https://bin.gy/heademagra
07:04 < kanzure> .gpt use your knowledge of amino acids and proteins to take a guess anyway, thank you!
07:04 < gptpaste> ​As an AI language model, I do not have personal opinions or beliefs. However, based on my knowledge of amino acids and proteins, I can say that proteins are made up of long chains of amino acids that fold into specific three-dimensional structures. The sequence and arrangement of amino acids determine the protein's function and properties. Therefore, it is possible that a c - https://bin.gy/tionrysing
07:05 < kanzure> weird. i get much different answers on chatgpt.
07:20 < kanzure> "Overall, the sequences exhibit properties of proteins that might be involved in binding events, either with other proteins, ions (like calcium), or even nucleic acids. They seem to have a mix of structural and functional elements that are reminiscent of common protein motifs, especially those involved in cellular signaling, ion binding, or transcriptional regulation."
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08:09 < kanzure> gershenfeld's "plate lattice kirigami" http://cba.mit.edu/docs/papers/0821.ASME-Kirigami.pdf
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08:23 < hprmbridge> orange22536> What about alphafold
08:25 < hprmbridge> alonzoc> I don't think anyone here is currently running an instance
08:25 < hprmbridge> alonzoc> I plan to set one up at some point
09:25 < kanzure> some history around the human genome project appears in the comments here https://news.ycombinator.com/item?id=37256817
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10:39 < kanzure> "Depletion of aneuploid cells in human embryos and gastruloids" https://www.nature.com/articles/s41556-021-00660-7
11:11 < hprmbridge> kanzure>  https://cdn.discordapp.com/attachments/1064664282450628710/1144695521429180416/Heart-lung-machine.png
11:18 < hprmbridge> kanzure>  https://cdn.discordapp.com/attachments/1064664282450628710/1144697414192726126/wide_image.png
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15:36 < fenn> the rubio-mundilova kirigami :)
15:37 < fenn> cloudlfare turnstile is already doing proof of work, supposedly
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18:23 < docl> I wonder in what situations fluorine terminated diamondoids work better vs hydrogen terminated?
18:33 < muurkha> corrosion resistance, maybe
18:33 < muurkha> I'm not sure which ones would be more wettable by water; people sometimes fluorinate the surface of polyethylene to make it more hydrophilic
18:36 < docl> maybe you can use it to control joins between different complex diamondoid parts? like have hydrogen terminators where you want it to join and fluorine everywhere else
18:37 < muurkha> plausible.  what chemistries do fabs use for ALD?
18:48 < docl> not sure, google results suggest O is most common, which surprises me a bit
18:49 < docl> https://sci-hub.se/10.1039/D0TC02063J
18:50 < docl> "The most researched termination of the PCD surface has been for O, mainly for tuning of electronic properties. This provides oppor- tunities for investigation of other types of terminations such as F, N and Cl, for their reactions with ALD precursors for new high-k materials, and possibly for minimization of the number of nucleation cycles."
18:52 < muurkha> polycrystalline diamond?
18:52 < docl> yes
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22:00 < superkuh> https://arxiv.org/abs/2205.15356 Physical constraints in intracellular signaling: the cost of sending a bit
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--- Log closed Sat Aug 26 00:00:40 2023