--- Log opened Wed Oct 04 00:00:45 2023
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01:32 < sphertext_> the language police 
01:33 < sphertext_> sir do you hold a permit for using this word
01:34 < fenn> you have to trademark it and defend your trademark
01:35 < sphertext_> i think trademarks are only for proper names. not for definitions 
03:07 < jrayhawk> you just have to trade in the thing you've defined
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07:47 < muurkha> sphertext_: the Open Source Initiative did this, though their efforts to trademark "open source" were unsuccessful
07:48 < muurkha> eventually the sense will drift; look at "nice", "sturdy", "girl", and "very" for examples.  but 25 years is pretty good
07:54 < L29Ah> there are some longer-living examples, for instance Champagne wine can only be made in Champagne by the decree of friends of manufacturers who hate competition // https://en.wikipedia.org/wiki/Champagne#Right_to_the_name_Champagne
07:55 < L29Ah> ohhh there's Chimpagne!
07:56 < muurkha> L29Ah: champagne had been made outside Champagne for generations before those decrees
07:57 < muurkha> and if I go to the supermarket and buy a bottle of champagne, it is very unlikely to be from Champagne
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09:19 < ike8> muurkha, sphertext_: I picked up some alpha-galactosidase; will report back in a few weeks.
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13:05 < hprmbridge> kanzure> "Assembly theory" https://twitter.com/leecronin/status/1709613311879479349
13:05 < hprmbridge> kanzure> https://www.nature.com/articles/s41586-023-06600-9
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13:31 < fenn> .t https://www.science.org/doi/10.1126/sciadv.adh8508
13:31 < EmmyNoether> HTTPError: HTTP Error 403: Forbidden (title:75)
13:31 < fenn> really
13:31 < fenn> Ultrafast dense DNA functionalization of quantum dots and rods for scalable 2D array fabrication with nanoscale precision
13:31 < fenn> this kind of thing might make chip fabs obsolete, eventually
13:41 < fenn> they need to work on crystal defects in the DNA origami lattice. a predetermined assembly sequence with many identical tiles that only go together one way would stop large masses from aggregating all at once
13:44 < fenn> you could even do stuff like flow in labeled origami tiles with fluorophores attached, into a microwell, wait until it attaches and the crossover strand gets ligated and some sort of F-RET fluorescence indicates that it happened
13:45 < fenn> do that one tile at a time
13:45 < fenn> ... now scale up to a billion heh
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16:06 < hprmbridge> nmz787> mmmm, want me some CHIMPagne
16:20 < sphertext> ike8 that's pretty specific for only certain carbs, maybe i would have started with a mixture like https://en.wikipedia.org/wiki/Pancreatic_enzymes_(medication) then try to narrow it down. or maybe what you got will help, who knows 
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16:52 < ike8> sphertext: pre-formulated stacks are scary. Too many variables. One enzyme at a time. I chose this one because its not endogenous, so i'm hoping it won't downregulate with my body's natural enzyme production.
17:49 < hprmbridge> kanzure> a review of structural biology https://arxiv.org/abs/2310.01792
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--- Log closed Thu Oct 05 00:00:46 2023